Induction of apoptosis by the oolong tea polyphenol theasinensin A through cytochrome c release and activation of caspase-9 and caspase-3 in human u937 cells

Journal of Agricultural and Food Chemistry

Volumn 48, Issue 12, 2000, Pages 6337-6346

  Pan, Min Hsiung ^a   Liang, Yu Chih ^a   Lin Shiau, Shoei Yn ^a   Zhu, Nan Qun ^b   Ho, Chi Tang ^b   Lin, Jen Kun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Apoptosis; Caspase; Oolong tea; Theasinensin A; U937 cells

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DEOXYRIBONUCLEASE; EPIGALLOCATECHIN GALLATE; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOCORTIN 5; MITOCHONDRIAL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYPHENOL; REACTIVE OXYGEN METABOLITE; THEAFLAVIN; THEAFLAVIN 3,3' DIGALLATE; THEASINENSIN A; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE POTENTIAL; CELL STRAIN U937; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INDUCTION; ENZYME RELEASE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE; TEA;

APOPTOSIS; CASPASE 3; CASPASE 9; CASPASES; CYTOCHROME C GROUP; FLAVONOIDS; HUMANS; PHENOLS; POLYMERS; TEA; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0034524815     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf000777b     Document Type: Article

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