메뉴 건너뛰기




Volumn 48, Issue 1, 2011, Pages 106-114

Optical advances in skeletal imaging applied to bone metastases

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; BIOLUMINESCENCE; BONE METASTASIS; BONE RADIOGRAPHY; CANCER RESEARCH; DIAGNOSTIC IMAGING; FLUORESCENCE IMAGING; HUMAN; IMAGING SYSTEM; INFLAMMATION; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 78650309923     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.07.027     Document Type: Review
Times cited : (25)

References (105)
  • 1
    • 37049201118 scopus 로고
    • Rontgen rays
    • Pupin M.I. Rontgen rays. Science 1896, 3:231-235.
    • (1896) Science , vol.3 , pp. 231-235
    • Pupin, M.I.1
  • 2
    • 0007015743 scopus 로고
    • On a new kind of rays
    • Rontgen W.C. On a new kind of rays. Science 1896, 3:227-231.
    • (1896) Science , vol.3 , pp. 227-231
    • Rontgen, W.C.1
  • 3
    • 9444230176 scopus 로고
    • Experiments on the rontgen x-rays
    • Goodspeed A.W. Experiments on the rontgen x-rays. Science 1896, 3:236-237.
    • (1896) Science , vol.3 , pp. 236-237
    • Goodspeed, A.W.1
  • 4
    • 0015622338 scopus 로고
    • Computerized transverse axial tomography
    • Ambrose J., Hounsfield G. Computerized transverse axial tomography. Br J Radiol 1973, 46:148-149.
    • (1973) Br J Radiol , vol.46 , pp. 148-149
    • Ambrose, J.1    Hounsfield, G.2
  • 5
    • 0015911128 scopus 로고
    • Computerized transverse axial scanning (tomography). 1. Description of system
    • Hounsfield G.N. Computerized transverse axial scanning (tomography). 1. Description of system. Br J Radiol 1973, 46:1016-1022.
    • (1973) Br J Radiol , vol.46 , pp. 1016-1022
    • Hounsfield, G.N.1
  • 7
    • 0041736619 scopus 로고    scopus 로고
    • Evaluation of effector cell fate and function by in vivo bioluminescence imaging
    • Edinger M., Hoffmann P., Contag C.H., Negrin R.S. Evaluation of effector cell fate and function by in vivo bioluminescence imaging. Methods 2003, 31:172-179.
    • (2003) Methods , vol.31 , pp. 172-179
    • Edinger, M.1    Hoffmann, P.2    Contag, C.H.3    Negrin, R.S.4
  • 8
    • 25844461626 scopus 로고    scopus 로고
    • The multiple uses of fluorescent proteins to visualize cancer in vivo
    • Hoffman R.M. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 2005, 5:796-806.
    • (2005) Nat Rev Cancer , vol.5 , pp. 796-806
    • Hoffman, R.M.1
  • 11
    • 39049096552 scopus 로고    scopus 로고
    • Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening
    • Michelini E., Cevenini L., Mezzanotte L., Ablamsky D., Southworth T., Branchini B., et al. Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening. Anal Chem 2008, 80:260-267.
    • (2008) Anal Chem , vol.80 , pp. 260-267
    • Michelini, E.1    Cevenini, L.2    Mezzanotte, L.3    Ablamsky, D.4    Southworth, T.5    Branchini, B.6
  • 13
    • 0037039437 scopus 로고    scopus 로고
    • Optical imaging of Renilla luciferase reporter gene expression in living mice
    • Bhaumik S., Gambhir S.S. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci USA 2002, 99:377-382.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 377-382
    • Bhaumik, S.1    Gambhir, S.S.2
  • 14
    • 0029939559 scopus 로고    scopus 로고
    • Chemistries and colors of bioluminescent reactions: a review
    • Hastings J.W. Chemistries and colors of bioluminescent reactions: a review. Gene 1996, 173:5-11.
    • (1996) Gene , vol.173 , pp. 5-11
    • Hastings, J.W.1
  • 15
    • 1242342217 scopus 로고    scopus 로고
    • Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine
    • Pichler A., Prior J.L., Piwnica-Worms D. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc Natl Acad Sci USA 2004, 101:1702-1707.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1702-1707
    • Pichler, A.1    Prior, J.L.2    Piwnica-Worms, D.3
  • 16
    • 14044250981 scopus 로고    scopus 로고
    • Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
    • Tannous B.A., Kim D.E., Fernandez J.L., Weissleder R., Breakefield X.O. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 2005, 11:435-443.
    • (2005) Mol Ther , vol.11 , pp. 435-443
    • Tannous, B.A.1    Kim, D.E.2    Fernandez, J.L.3    Weissleder, R.4    Breakefield, X.O.5
  • 17
    • 77954062987 scopus 로고    scopus 로고
    • Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases
    • Chung E., Yamashita H., Au P., Tannous B.A., Fukumura D., Jain R.K. Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases. PLoS ONE 2009, 4:e8316.
    • (2009) PLoS ONE , vol.4
    • Chung, E.1    Yamashita, H.2    Au, P.3    Tannous, B.A.4    Fukumura, D.5    Jain, R.K.6
  • 18
    • 13444268127 scopus 로고    scopus 로고
    • Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
    • Minn A.J., Kang Y., Serganova I., Gupta G.P., Giri D.D., Doubrovin M., et al. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest 2005, 115:44-55.
    • (2005) J Clin Invest , vol.115 , pp. 44-55
    • Minn, A.J.1    Kang, Y.2    Serganova, I.3    Gupta, G.P.4    Giri, D.D.5    Doubrovin, M.6
  • 19
    • 0008662621 scopus 로고
    • Measurement of photoluminescence quantum yields. A review
    • Demas J.N., Crosby G.A. Measurement of photoluminescence quantum yields. A review. J Phys Chem 1971, 75:991-1024.
    • (1971) J Phys Chem , vol.75 , pp. 991-1024
    • Demas, J.N.1    Crosby, G.A.2
  • 20
    • 0037236238 scopus 로고    scopus 로고
    • Shedding light onto live molecular targets
    • Weissleder R., Ntziachristos V. Shedding light onto live molecular targets. Nat Med 2003, 9:123-128.
    • (2003) Nat Med , vol.9 , pp. 123-128
    • Weissleder, R.1    Ntziachristos, V.2
  • 22
    • 33645798851 scopus 로고    scopus 로고
    • The fluorescent toolbox for assessing protein location and function
    • Giepmans B.N., Adams S.R., Ellisman M.H., Tsien R.Y. The fluorescent toolbox for assessing protein location and function. Science 2006, 312:217-224.
    • (2006) Science , vol.312 , pp. 217-224
    • Giepmans, B.N.1    Adams, S.R.2    Ellisman, M.H.3    Tsien, R.Y.4
  • 25
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
    • Shaner N.C., Campbell R.E., Steinbach P.A., Giepmans B.N., Palmer A.E., Tsien R.Y. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 2004, 22:1567-1572.
    • (2004) Nat Biotechnol , vol.22 , pp. 1567-1572
    • Shaner, N.C.1    Campbell, R.E.2    Steinbach, P.A.3    Giepmans, B.N.4    Palmer, A.E.5    Tsien, R.Y.6
  • 26
    • 10044227172 scopus 로고    scopus 로고
    • Evolution of new nonantibody proteins via iterative somatic hypermutation
    • Wang L., Jackson W.C., Steinbach P.A., Tsien R.Y. Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci USA 2004, 101:16745-16749.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16745-16749
    • Wang, L.1    Jackson, W.C.2    Steinbach, P.A.3    Tsien, R.Y.4
  • 27
    • 65649113981 scopus 로고    scopus 로고
    • Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome
    • Shu X., Royant A., Lin M.Z., Aguilera T.A., Lev-Ram V., Steinbach P.A., et al. Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome. Science 2009, 324:804-807.
    • (2009) Science , vol.324 , pp. 804-807
    • Shu, X.1    Royant, A.2    Lin, M.Z.3    Aguilera, T.A.4    Lev-Ram, V.5    Steinbach, P.A.6
  • 28
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • Weissleder R., Tung C.H., Mahmood U., Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 1999, 17:375-378.
    • (1999) Nat Biotechnol , vol.17 , pp. 375-378
    • Weissleder, R.1    Tung, C.H.2    Mahmood, U.3    Bogdanov, A.4
  • 31
    • 84934434915 scopus 로고    scopus 로고
    • Validation of bioluminescent imaging techniques
    • Virostko J., Jansen E.D. Validation of bioluminescent imaging techniques. Methods Mol Biol 2009, 574:15-23.
    • (2009) Methods Mol Biol , vol.574 , pp. 15-23
    • Virostko, J.1    Jansen, E.D.2
  • 32
    • 72449167429 scopus 로고    scopus 로고
    • Adaptive improved element free Galerkin method for quasi- or multi-spectral bioluminescence tomography
    • Qin C., Yang X., Feng J., Liu K., Liu J., Yan G., et al. Adaptive improved element free Galerkin method for quasi- or multi-spectral bioluminescence tomography. Opt Express 2009, 17:21925-21934.
    • (2009) Opt Express , vol.17 , pp. 21925-21934
    • Qin, C.1    Yang, X.2    Feng, J.3    Liu, K.4    Liu, J.5    Yan, G.6
  • 33
    • 39049121564 scopus 로고    scopus 로고
    • Quantitative bioluminescence tomography guided by diffuse optical tomography
    • Zhang Q., Yin L., Tan Y., Yuan Z., Jiang H. Quantitative bioluminescence tomography guided by diffuse optical tomography. Opt Express 2008, 16:1481-1486.
    • (2008) Opt Express , vol.16 , pp. 1481-1486
    • Zhang, Q.1    Yin, L.2    Tan, Y.3    Yuan, Z.4    Jiang, H.5
  • 34
    • 73249116830 scopus 로고    scopus 로고
    • Pre-clinical whole-body fluorescence imaging: review of instruments, methods and applications
    • Leblond F., Davis S.C., Valdes P.A., Pogue B.W. Pre-clinical whole-body fluorescence imaging: review of instruments, methods and applications. J Photochem Photobiol B 2010, 98:77-94.
    • (2010) J Photochem Photobiol B , vol.98 , pp. 77-94
    • Leblond, F.1    Davis, S.C.2    Valdes, P.A.3    Pogue, B.W.4
  • 36
    • 29944432176 scopus 로고    scopus 로고
    • Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging
    • Mansfield J.R., Gossage K.W., Hoyt C.C., Levenson R.M. Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging. J Biomed Opt 2005, 10:41207.
    • (2005) J Biomed Opt , vol.10 , pp. 41207
    • Mansfield, J.R.1    Gossage, K.W.2    Hoyt, C.C.3    Levenson, R.M.4
  • 38
    • 56749107194 scopus 로고    scopus 로고
    • The tumor microenvironment and its contribution to tumor evolution toward metastasis
    • Lorusso G., Ruegg C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol 2008, 130:1091-1103.
    • (2008) Histochem Cell Biol , vol.130 , pp. 1091-1103
    • Lorusso, G.1    Ruegg, C.2
  • 39
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: causes, consequences and therapeutic opportunities
    • Mundy G.R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002, 2:584-593.
    • (2002) Nat Rev Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 40
    • 33747181617 scopus 로고    scopus 로고
    • Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation
    • Voorzanger-Rousselot N., Juillet F., Mareau E., Zimmermann J., Kalebic T., Garnero P. Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation. Br J Cancer 2006, 95:506-514.
    • (2006) Br J Cancer , vol.95 , pp. 506-514
    • Voorzanger-Rousselot, N.1    Juillet, F.2    Mareau, E.3    Zimmermann, J.4    Kalebic, T.5    Garnero, P.6
  • 41
    • 0142250340 scopus 로고    scopus 로고
    • Transforming growth factor-beta in osteolytic breast cancer bone metastases
    • Guise T.A., Chirgwin J.M. Transforming growth factor-beta in osteolytic breast cancer bone metastases. Clin Orthop Relat Res 2003, S32-S38.
    • (2003) Clin Orthop Relat Res
    • Guise, T.A.1    Chirgwin, J.M.2
  • 42
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin W.W., Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 2007, 117:1175-1183.
    • (2007) J Clin Invest , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 44
  • 45
    • 78650309913 scopus 로고    scopus 로고
    • Effective bone labeling for in vivo NIR noninvasive imaging in nude mice
    • Providence, Rhode Island. 9-9-2007.Ref Type: Abstract.
    • Kovar JL, Xu X, Simpson MA, and Olive DM. Effective bone labeling for in vivo NIR noninvasive imaging in nude mice. Joint Molecular Imaging Conference-Sept. 2007, Providence, Rhode Island. 9-9-2007.Ref Type: Abstract.
    • (2007) Joint Molecular Imaging Conference-Sept
    • Kovar, J.L.1    Xu, X.2    Simpson, M.A.3    Olive, D.M.4
  • 47
    • 77955736518 scopus 로고    scopus 로고
    • Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo
    • Kozloff K.M., Volakis L.I., Marini J.C., Caird M.S. Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo. J Bone Miner Res 2010.
    • (2010) J Bone Miner Res
    • Kozloff, K.M.1    Volakis, L.I.2    Marini, J.C.3    Caird, M.S.4
  • 48
    • 0024262906 scopus 로고
    • A murine model of experimental metastasis to bone and bone marrow
    • Arguello F., Baggs R.B., Frantz C.N. A murine model of experimental metastasis to bone and bone marrow. Cancer Res 1988, 48:6876-6881.
    • (1988) Cancer Res , vol.48 , pp. 6876-6881
    • Arguello, F.1    Baggs, R.B.2    Frantz, C.N.3
  • 49
    • 34248594553 scopus 로고    scopus 로고
    • Metastasis: recent discoveries and novel treatment strategies
    • Eccles S.A., Welch D.R. Metastasis: recent discoveries and novel treatment strategies. Lancet 2007, 369:1742-1757.
    • (2007) Lancet , vol.369 , pp. 1742-1757
    • Eccles, S.A.1    Welch, D.R.2
  • 50
    • 33748331308 scopus 로고    scopus 로고
    • The mighty mouse: genetically engineered mouse models in cancer drug development
    • Sharpless N.E., Depinho R.A. The mighty mouse: genetically engineered mouse models in cancer drug development. Nat Rev Drug Discov 2006, 5:741-754.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 741-754
    • Sharpless, N.E.1    Depinho, R.A.2
  • 51
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: mechanistic insights and clinical challenges
    • Steeg P.S. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006, 12:895-904.
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 52
    • 0036118348 scopus 로고    scopus 로고
    • Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease
    • Wetterwald A., van der Pluijm G., Que I., Sijmons B., Buijs J., Karperien M., et al. Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease. Am J Pathol 2002, 160:1143-1153.
    • (2002) Am J Pathol , vol.160 , pp. 1143-1153
    • Wetterwald, A.1    van der Pluijm, G.2    Que, I.3    Sijmons, B.4    Buijs, J.5    Karperien, M.6
  • 53
    • 79960785065 scopus 로고    scopus 로고
    • In vivo visualization of metastatic prostate cancer and quantitation of disease progression in immunocompromised mice
    • Kalikin L.M., Schneider A., Thakur M.A., Fridman Y., Griffin L.B., Dunn R.L., et al. In vivo visualization of metastatic prostate cancer and quantitation of disease progression in immunocompromised mice. Cancer Biol Ther 2003, 2:656-660.
    • (2003) Cancer Biol Ther , vol.2 , pp. 656-660
    • Kalikin, L.M.1    Schneider, A.2    Thakur, M.A.3    Fridman, Y.4    Griffin, L.B.5    Dunn, R.L.6
  • 55
    • 58149354373 scopus 로고    scopus 로고
    • A redshifted codon-optimized firefly luciferase is a sensitive reporter for bioluminescence imaging
    • Caysa H., Jacob R., Muther N., Branchini B., Messerle M., Soling A. A redshifted codon-optimized firefly luciferase is a sensitive reporter for bioluminescence imaging. Photochem Photobiol Sci 2009, 8:52-56.
    • (2009) Photochem Photobiol Sci , vol.8 , pp. 52-56
    • Caysa, H.1    Jacob, R.2    Muther, N.3    Branchini, B.4    Messerle, M.5    Soling, A.6
  • 56
    • 77949652141 scopus 로고    scopus 로고
    • Non-invasive detection of a small number of bioluminescent cancer cells in vivo
    • Kim J.B., Urban K., Cochran E., Lee S., Ang A., Rice B., et al. Non-invasive detection of a small number of bioluminescent cancer cells in vivo. PLoS ONE 2010, 5:e9364.
    • (2010) PLoS ONE , vol.5
    • Kim, J.B.1    Urban, K.2    Cochran, E.3    Lee, S.4    Ang, A.5    Rice, B.6
  • 57
    • 0034999898 scopus 로고    scopus 로고
    • Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases
    • van der Pluijm G., Sijmons B., Vloedgraven H., Deckers M., Papapoulos S., Lowik C. Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases. J Bone Miner Res 2001, 16:1077-1091.
    • (2001) J Bone Miner Res , vol.16 , pp. 1077-1091
    • van der Pluijm, G.1    Sijmons, B.2    Vloedgraven, H.3    Deckers, M.4    Papapoulos, S.5    Lowik, C.6
  • 58
    • 33845891067 scopus 로고    scopus 로고
    • Purification method directly influences effectiveness of an epidermal growth factor-coupled targeting agent for noninvasive tumor detection in mice
    • Kovar J.L., Volcheck W.M., Chen J., Simpson M.A. Purification method directly influences effectiveness of an epidermal growth factor-coupled targeting agent for noninvasive tumor detection in mice. Anal Biochem 2007, 361:47-54.
    • (2007) Anal Biochem , vol.361 , pp. 47-54
    • Kovar, J.L.1    Volcheck, W.M.2    Chen, J.3    Simpson, M.A.4
  • 59
    • 56949097880 scopus 로고    scopus 로고
    • Characterization and performance of a near-infrared 2-deoxyglucose optical imaging agent for mouse cancer models
    • Kovar J.L., Volcheck W., Sevick-Muraca E., Simpson M.A., Olive D.M. Characterization and performance of a near-infrared 2-deoxyglucose optical imaging agent for mouse cancer models. Anal Biochem 2009, 384:254-262.
    • (2009) Anal Biochem , vol.384 , pp. 254-262
    • Kovar, J.L.1    Volcheck, W.2    Sevick-Muraca, E.3    Simpson, M.A.4    Olive, D.M.5
  • 61
    • 76749085636 scopus 로고    scopus 로고
    • In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore
    • Gong H., Kovar J., Little G., Chen H., Olive D.M. In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore. Neoplasia 2010, 12:139-149.
    • (2010) Neoplasia , vol.12 , pp. 139-149
    • Gong, H.1    Kovar, J.2    Little, G.3    Chen, H.4    Olive, D.M.5
  • 62
    • 77951214012 scopus 로고    scopus 로고
    • Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice
    • Zhou H., Luby-Phelps K., Mickey B.E., Habib A.A., Mason R.P., Zhao D. Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice. PLoS ONE 2009, 4:e8051.
    • (2009) PLoS ONE , vol.4
    • Zhou, H.1    Luby-Phelps, K.2    Mickey, B.E.3    Habib, A.A.4    Mason, R.P.5    Zhao, D.6
  • 63
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R., Akhurst R.J., Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001, 29:117-129.
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 64
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J. TGFbeta in Cancer. Cell 2008, 134:215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 65
    • 0032918414 scopus 로고    scopus 로고
    • TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
    • Yin J.J., Selander K., Chirgwin J.M., Dallas M., Grubbs B.G., Wieser R., et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 1999, 103:197-206.
    • (1999) J Clin Invest , vol.103 , pp. 197-206
    • Yin, J.J.1    Selander, K.2    Chirgwin, J.M.3    Dallas, M.4    Grubbs, B.G.5    Wieser, R.6
  • 66
    • 33644534795 scopus 로고    scopus 로고
    • The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells
    • Deckers M., van Dinther M., Buijs J., Que I., Lowik C., van der Pluijm G., et al. The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells. Cancer Res 2006, 66:2202-2209.
    • (2006) Cancer Res , vol.66 , pp. 2202-2209
    • Deckers, M.1    van Dinther, M.2    Buijs, J.3    Que, I.4    Lowik, C.5    van der Pluijm, G.6
  • 67
    • 25444479744 scopus 로고    scopus 로고
    • Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
    • Kang Y., He W., Tulley S., Gupta G.P., Serganova I., Chen C.R., et al. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proc Natl Acad Sci USA 2005, 102:13909-13914.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13909-13914
    • Kang, Y.1    He, W.2    Tulley, S.3    Gupta, G.P.4    Serganova, I.5    Chen, C.R.6
  • 69
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum S.L. Bone resorption by osteoclasts. Science 2000, 289:1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 70
    • 15844422855 scopus 로고    scopus 로고
    • Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts
    • Drake F.H., Dodds R.A., James I.E., Connor J.R., Debouck C., Richardson S., et al. Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts. J Biol Chem 1996, 271:12511-12516.
    • (1996) J Biol Chem , vol.271 , pp. 12511-12516
    • Drake, F.H.1    Dodds, R.A.2    James, I.E.3    Connor, J.R.4    Debouck, C.5    Richardson, S.6
  • 71
    • 0033610853 scopus 로고    scopus 로고
    • The collagenolytic activity of cathepsin K is unique among mammalian proteinases
    • Garnero P., Borel O., Byrjalsen I., Ferreras M., Drake F.H., McQueney M.S., et al. The collagenolytic activity of cathepsin K is unique among mammalian proteinases. J Biol Chem 1998, 273:32347-32352.
    • (1998) J Biol Chem , vol.273 , pp. 32347-32352
    • Garnero, P.1    Borel, O.2    Byrjalsen, I.3    Ferreras, M.4    Drake, F.H.5    McQueney, M.S.6
  • 72
    • 0142169545 scopus 로고    scopus 로고
    • Probing cathepsin K activity with a selective substrate spanning its active site
    • Lecaille F., Weidauer E., Juliano M.A., Bromme D., Lalmanach G. Probing cathepsin K activity with a selective substrate spanning its active site. Biochem J 2003, 375:307-312.
    • (2003) Biochem J , vol.375 , pp. 307-312
    • Lecaille, F.1    Weidauer, E.2    Juliano, M.A.3    Bromme, D.4    Lalmanach, G.5
  • 73
    • 58249120523 scopus 로고    scopus 로고
    • Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo
    • Kozloff K.M., Quinti L., Patntirapong S., Hauschka P.V., Tung C.H., Weissleder R., et al. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone 2009, 44:190-198.
    • (2009) Bone , vol.44 , pp. 190-198
    • Kozloff, K.M.1    Quinti, L.2    Patntirapong, S.3    Hauschka, P.V.4    Tung, C.H.5    Weissleder, R.6
  • 74
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer C., Tung C.H., Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001, 7:743-748.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3
  • 75
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: regulators of the tumor microenvironment
    • Kessenbrock K., Plaks V., Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010, 141:52-67.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 76
    • 33746223025 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo
    • Deguchi J.O., Aikawa M., Tung C.H., Aikawa E., Kim D.E., Ntziachristos V., et al. Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Circulation 2006, 114:55-62.
    • (2006) Circulation , vol.114 , pp. 55-62
    • Deguchi, J.O.1    Aikawa, M.2    Tung, C.H.3    Aikawa, E.4    Kim, D.E.5    Ntziachristos, V.6
  • 77
    • 77957363988 scopus 로고    scopus 로고
    • Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live Fibulin-4 mice
    • Kaijzel E.L., van Heijningen P., Wielopolski P., Vermeij M., Koning G., van Cappellen W.A., et al. Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live Fibulin-4 mice. Circ Cardiovasc Imaging 2010, 3:567-577.
    • (2010) Circ Cardiovasc Imaging , vol.3 , pp. 567-577
    • Kaijzel, E.L.1    van Heijningen, P.2    Wielopolski, P.3    Vermeij, M.4    Koning, G.5    van Cappellen, W.A.6
  • 78
    • 0036066218 scopus 로고    scopus 로고
    • Fluorescence molecular tomography resolves protease activity in vivo
    • Ntziachristos V., Tung C.H., Bremer C., Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo. Nat Med 2002, 8:757-760.
    • (2002) Nat Med , vol.8 , pp. 757-760
    • Ntziachristos, V.1    Tung, C.H.2    Bremer, C.3    Weissleder, R.4
  • 80
    • 33644825565 scopus 로고    scopus 로고
    • Dynamic imaging of protease activity with fluorescently quenched activity-based probes
    • Blum G., Mullins S.R., Keren K., Fonovic M., Jedeszko C., Rice M.J., et al. Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nat Chem Biol 2005, 1:203-209.
    • (2005) Nat Chem Biol , vol.1 , pp. 203-209
    • Blum, G.1    Mullins, S.R.2    Keren, K.3    Fonovic, M.4    Jedeszko, C.5    Rice, M.J.6
  • 81
    • 68149166462 scopus 로고    scopus 로고
    • Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity
    • Blum G., Weimer R.M., Edgington L.E., Adams W., Bogyo M. Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity. PLoS ONE 2009, 4:e6374.
    • (2009) PLoS ONE , vol.4
    • Blum, G.1    Weimer, R.M.2    Edgington, L.E.3    Adams, W.4    Bogyo, M.5
  • 82
    • 34548666006 scopus 로고    scopus 로고
    • Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
    • Blum G., von Degenfeld G., Merchant M.J., Blau H.M., Bogyo M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol 2007, 3:668-677.
    • (2007) Nat Chem Biol , vol.3 , pp. 668-677
    • Blum, G.1    von Degenfeld, G.2    Merchant, M.J.3    Blau, H.M.4    Bogyo, M.5
  • 83
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer B., Wizigmann-Voos S., Schnurch H., Martinez R., Moller N.P., Risau W., et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993, 72:835-846.
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6
  • 84
    • 0030938919 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries
    • Couffinhal T., Kearney M., Witzenbichler B., Chen D., Murohara T., Losordo D.W., et al. Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and atherosclerotic human arteries. Am J Pathol 1997, 150:1673-1685.
    • (1997) Am J Pathol , vol.150 , pp. 1673-1685
    • Couffinhal, T.1    Kearney, M.2    Witzenbichler, B.3    Chen, D.4    Murohara, T.5    Losordo, D.W.6
  • 85
    • 0036105785 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration
    • Rissanen T.T., Vajanto I., Hiltunen M.O., Rutanen J., Kettunen M.I., Niemi M., et al. Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration. Am J Pathol 2002, 160:1393-1403.
    • (2002) Am J Pathol , vol.160 , pp. 1393-1403
    • Rissanen, T.T.1    Vajanto, I.2    Hiltunen, M.O.3    Rutanen, J.4    Kettunen, M.I.5    Niemi, M.6
  • 86
    • 0036200384 scopus 로고    scopus 로고
    • Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2
    • Vajkoczy P., Farhadi M., Gaumann A., Heidenreich R., Erber R., Wunder A., et al. Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2. J Clin Invest 2002, 109:777-785.
    • (2002) J Clin Invest , vol.109 , pp. 777-785
    • Vajkoczy, P.1    Farhadi, M.2    Gaumann, A.3    Heidenreich, R.4    Erber, R.5    Wunder, A.6
  • 87
    • 0036289044 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia
    • Witmer A.N., Dai J., Weich H.A., Vrensen G.F., Schlingemann R.O. Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia. J Histochem Cytochem 2002, 50:767-777.
    • (2002) J Histochem Cytochem , vol.50 , pp. 767-777
    • Witmer, A.N.1    Dai, J.2    Weich, H.A.3    Vrensen, G.F.4    Schlingemann, R.O.5
  • 88
    • 0942298606 scopus 로고    scopus 로고
    • Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse
    • Zhang N., Fang Z., Contag P.R., Purchio A.F., West D.B. Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse. Blood 2004, 103:617-626.
    • (2004) Blood , vol.103 , pp. 617-626
    • Zhang, N.1    Fang, Z.2    Contag, P.R.3    Purchio, A.F.4    West, D.B.5
  • 89
    • 0030058001 scopus 로고    scopus 로고
    • Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoter
    • Ronicke V., Risau W., Breier G. Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoter. Circ Res 1996, 79:277-285.
    • (1996) Circ Res , vol.79 , pp. 277-285
    • Ronicke, V.1    Risau, W.2    Breier, G.3
  • 90
    • 33746265319 scopus 로고    scopus 로고
    • Surface immobilization of active vascular endothelial growth factor via a cysteine-containing tag
    • Backer M.V., Patel V., Jehning B.T., Claffey K.P., Backer J.M. Surface immobilization of active vascular endothelial growth factor via a cysteine-containing tag. Biomaterials 2006, 27:5452-5458.
    • (2006) Biomaterials , vol.27 , pp. 5452-5458
    • Backer, M.V.1    Patel, V.2    Jehning, B.T.3    Claffey, K.P.4    Backer, J.M.5
  • 91
    • 84934442275 scopus 로고    scopus 로고
    • Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins
    • Backer M.V., Levashova Z., Levenson R., Blankenberg F.G., Backer J.M. Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins. Methods Mol Biol 2008, 494:275-294.
    • (2008) Methods Mol Biol , vol.494 , pp. 275-294
    • Backer, M.V.1    Levashova, Z.2    Levenson, R.3    Blankenberg, F.G.4    Backer, J.M.5
  • 93
    • 44349154751 scopus 로고    scopus 로고
    • Direct site-specific labeling of the Cys-tag moiety in scVEGF with technetium 99m
    • Levashova Z., Backer M., Backer J.M., Blankenberg F.G. Direct site-specific labeling of the Cys-tag moiety in scVEGF with technetium 99m. Bioconjug Chem 2008, 19:1049-1054.
    • (2008) Bioconjug Chem , vol.19 , pp. 1049-1054
    • Levashova, Z.1    Backer, M.2    Backer, J.M.3    Blankenberg, F.G.4
  • 94
    • 73349132018 scopus 로고    scopus 로고
    • Imaging vascular endothelial growth factor (VEGF) receptors in turpentine-induced sterile thigh abscesses with radiolabeled single-chain VEGF
    • Levashova Z., Backer M., Backer J.M., Blankenberg F.G. Imaging vascular endothelial growth factor (VEGF) receptors in turpentine-induced sterile thigh abscesses with radiolabeled single-chain VEGF. J Nucl Med 2009, 50:2058-2063.
    • (2009) J Nucl Med , vol.50 , pp. 2058-2063
    • Levashova, Z.1    Backer, M.2    Backer, J.M.3    Blankenberg, F.G.4
  • 95
    • 34147191481 scopus 로고    scopus 로고
    • Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes
    • Backer M.V., Levashova Z., Patel V., Jehning B.T., Claffey K., Blankenberg F.G., et al. Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes. Nat Med 2007, 13:504-509.
    • (2007) Nat Med , vol.13 , pp. 504-509
    • Backer, M.V.1    Levashova, Z.2    Patel, V.3    Jehning, B.T.4    Claffey, K.5    Blankenberg, F.G.6
  • 96
    • 0034090097 scopus 로고    scopus 로고
    • Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
    • Griffioen A.W., Molema G. Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000, 52:237-268.
    • (2000) Pharmacol Rev , vol.52 , pp. 237-268
    • Griffioen, A.W.1    Molema, G.2
  • 97
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks P.C., Clark R.A., Cheresh D.A. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994, 264:569-571.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 98
    • 0037023363 scopus 로고    scopus 로고
    • Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
    • Xiong J.P., Stehle T., Zhang R., Joachimiak A., Frech M., Goodman S.L., et al. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 2002, 296:151-155.
    • (2002) Science , vol.296 , pp. 151-155
    • Xiong, J.P.1    Stehle, T.2    Zhang, R.3    Joachimiak, A.4    Frech, M.5    Goodman, S.L.6
  • 99
    • 33746864082 scopus 로고    scopus 로고
    • Near-infrared fluorescence imaging of tumor integrin alpha v beta 3 expression with Cy7-labeled RGD multimers
    • Wu Y., Cai W., Chen X. Near-infrared fluorescence imaging of tumor integrin alpha v beta 3 expression with Cy7-labeled RGD multimers. Mol Imaging Biol 2006, 8:226-236.
    • (2006) Mol Imaging Biol , vol.8 , pp. 226-236
    • Wu, Y.1    Cai, W.2    Chen, X.3
  • 100
    • 33646394346 scopus 로고    scopus 로고
    • Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects
    • Cai W., Shin D.W., Chen K., Gheysens O., Cao Q., Wang S.X., et al. Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett 2006, 6:669-676.
    • (2006) Nano Lett , vol.6 , pp. 669-676
    • Cai, W.1    Shin, D.W.2    Chen, K.3    Gheysens, O.4    Cao, Q.5    Wang, S.X.6
  • 101
    • 7444235966 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
    • Chen X., Conti P.S., Moats R.A. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res 2004, 64:8009-8014.
    • (2004) Cancer Res , vol.64 , pp. 8009-8014
    • Chen, X.1    Conti, P.S.2    Moats, R.A.3
  • 102
    • 34250708569 scopus 로고    scopus 로고
    • Whole-body optical imaging in animal models to assess cancer development and progression
    • Kaijzel E.L., van der Pluijm G., Lowik C.W. Whole-body optical imaging in animal models to assess cancer development and progression. Clin Cancer Res 2007, 13:3490-3497.
    • (2007) Clin Cancer Res , vol.13 , pp. 3490-3497
    • Kaijzel, E.L.1    van der Pluijm, G.2    Lowik, C.W.3
  • 103
    • 78049350167 scopus 로고    scopus 로고
    • Dual in vivo quantification of integrin-targeted and protease-activated agents in cancer using fluorescence molecular tomography (FMT)
    • Kossodo S., Pickarski M., Lin S.A., Gleason A., Gaspar R., Buono C., et al. Dual in vivo quantification of integrin-targeted and protease-activated agents in cancer using fluorescence molecular tomography (FMT). Mol Imaging Biol 2009.
    • (2009) Mol Imaging Biol
    • Kossodo, S.1    Pickarski, M.2    Lin, S.A.3    Gleason, A.4    Gaspar, R.5    Buono, C.6
  • 104
    • 77955647641 scopus 로고    scopus 로고
    • 'In vivo' optical approaches to angiogenesis imaging
    • Snoeks T.J., Lowik C.W., Kaijzel E.L. 'In vivo' optical approaches to angiogenesis imaging. Angiogenesis 2010, 13:135-147.
    • (2010) Angiogenesis , vol.13 , pp. 135-147
    • Snoeks, T.J.1    Lowik, C.W.2    Kaijzel, E.L.3
  • 105
    • 0030223057 scopus 로고    scopus 로고
    • Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice
    • Pettaway C.A., Pathak S., Greene G., Ramirez E., Wilson M.R., Killion J.J., et al. Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res 1996, 2:1627-1636.
    • (1996) Clin Cancer Res , vol.2 , pp. 1627-1636
    • Pettaway, C.A.1    Pathak, S.2    Greene, G.3    Ramirez, E.4    Wilson, M.R.5    Killion, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.