메뉴 건너뛰기




Volumn 84, Issue 1, 2011, Pages 39-44

Adult rat hippocampal slices as in vitro models for neurodegeneration: Studies on cell viability and apoptotic processes

Author keywords

Apoptosis; Caspase 3; Hippocampus; Neurodegeneration; Slice culture; Trypan blue

Indexed keywords

CASPASE 3;

EID: 78650304196     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2010.10.008     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 33646115813 scopus 로고    scopus 로고
    • An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons
    • Ahboucha S., Coyne L., Hirakawa R., Butterworth R.F., Halliwell R.F. An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochem. Int. 2006, 48:703-707.
    • (2006) Neurochem. Int. , vol.48 , pp. 703-707
    • Ahboucha, S.1    Coyne, L.2    Hirakawa, R.3    Butterworth, R.F.4    Halliwell, R.F.5
  • 2
    • 0000968097 scopus 로고
    • Academic Press, New York, G. Paxinos (Ed.)
    • Amaral D.G., Witter M.P. The Rat Nervous System 1995, 443-493. Academic Press, New York. 2nd ed. G. Paxinos (Ed.).
    • (1995) The Rat Nervous System , pp. 443-493
    • Amaral, D.G.1    Witter, M.P.2
  • 4
    • 69449088403 scopus 로고    scopus 로고
    • Genomic analysis of ischemic preconditioning in adult rat hippocampal slice cultures
    • Benardete E.A., Bergold P.J. Genomic analysis of ischemic preconditioning in adult rat hippocampal slice cultures. Brain Res. 2009, 1292:107-122.
    • (2009) Brain Res. , vol.1292 , pp. 107-122
    • Benardete, E.A.1    Bergold, P.J.2
  • 5
    • 0042626611 scopus 로고    scopus 로고
    • Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures
    • Benninger F., Beck H., Wernig M., Tucker K.L., Brustle O., Scheffler B. Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures. J. Neurosci. 2003, 23:7075-7083.
    • (2003) J. Neurosci. , vol.23 , pp. 7075-7083
    • Benninger, F.1    Beck, H.2    Wernig, M.3    Tucker, K.L.4    Brustle, O.5    Scheffler, B.6
  • 6
    • 22544483518 scopus 로고    scopus 로고
    • Modulator effects of interleukin 1β and tumor necrosis factor-α on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures
    • Bernardino L., Xapelli S., Silva A.P., Jakobsen B., Poulsen F.R., Oliveira C.R., Vezzani A., Malva J.O., Zimmer J. Modulator effects of interleukin 1β and tumor necrosis factor-α on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J. Neurosci. 2005, 25:6734-6744.
    • (2005) J. Neurosci. , vol.25 , pp. 6734-6744
    • Bernardino, L.1    Xapelli, S.2    Silva, A.P.3    Jakobsen, B.4    Poulsen, F.R.5    Oliveira, C.R.6    Vezzani, A.7    Malva, J.O.8    Zimmer, J.9
  • 8
    • 33750412882 scopus 로고    scopus 로고
    • Temporal development of hippocampal cell death is dependent on tissue strain but not strain rate
    • Cater H.L., Sundstrom L.E., Morrison B. Temporal development of hippocampal cell death is dependent on tissue strain but not strain rate. J. Biomech. 2006, 39:2810-2818.
    • (2006) J. Biomech. , vol.39 , pp. 2810-2818
    • Cater, H.L.1    Sundstrom, L.E.2    Morrison, B.3
  • 10
    • 1842737533 scopus 로고    scopus 로고
    • Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures
    • Cho S., Liu D., Fairman D., Li P., Jenkins L., McGonigle P., Wood A. Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures. Neurochem. Int. 2004, 45:117-127.
    • (2004) Neurochem. Int. , vol.45 , pp. 117-127
    • Cho, S.1    Liu, D.2    Fairman, D.3    Li, P.4    Jenkins, L.5    McGonigle, P.6    Wood, A.7
  • 11
    • 33846071143 scopus 로고    scopus 로고
    • Protective effect of (4-methoxybenzylidene)-(3-methoxynophenyl)amine against neuronal cell death induced by oxygen and glucose deprivation in rat organotypic hippocampal slice culture
    • Choi S.Y., Kim S., Son D., Lee P., Lee J., Lee S., Kim D.S., Park Y., Kim S.Y. Protective effect of (4-methoxybenzylidene)-(3-methoxynophenyl)amine against neuronal cell death induced by oxygen and glucose deprivation in rat organotypic hippocampal slice culture. Biol. Pharmacol. Bull. 2007, 30:189-192.
    • (2007) Biol. Pharmacol. Bull. , vol.30 , pp. 189-192
    • Choi, S.Y.1    Kim, S.2    Son, D.3    Lee, P.4    Lee, J.5    Lee, S.6    Kim, D.S.7    Park, Y.8    Kim, S.Y.9
  • 12
  • 13
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U., Iadecola C., Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999, 22:391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 15
    • 0033787417 scopus 로고    scopus 로고
    • Age-dependent pre-and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain
    • Fabian-Fine R., Volknandt W., Fine A., Stewart M.G. Age-dependent pre-and postsynaptic distribution of AMPA receptors at synapses in CA3 stratum radiatum of hippocampal slice cultures compared with intact brain. Eur. J. Neurosci. 2000, 12:3687-3700.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3687-3700
    • Fabian-Fine, R.1    Volknandt, W.2    Fine, A.3    Stewart, M.G.4
  • 16
    • 0030970350 scopus 로고    scopus 로고
    • Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus
    • Figiel I., Kaczmarek L. Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus. Neurochem. Int. 1997, 31:229-240.
    • (1997) Neurochem. Int. , vol.31 , pp. 229-240
    • Figiel, I.1    Kaczmarek, L.2
  • 17
    • 1242292444 scopus 로고    scopus 로고
    • Functional validation of adult hippocampal organotypic cultures as an in vitro model of brain injury
    • Finley M., Fairman D., Liu D., Li P., Wood A., Cho S. Functional validation of adult hippocampal organotypic cultures as an in vitro model of brain injury. Brain Res. 2004, 1001:125-132.
    • (2004) Brain Res. , vol.1001 , pp. 125-132
    • Finley, M.1    Fairman, D.2    Liu, D.3    Li, P.4    Wood, A.5    Cho, S.6
  • 19
    • 2342604385 scopus 로고    scopus 로고
    • Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: effect of diazepam
    • Galeffi F., Sah R., Pond B.B., George A., Schwartz-Bloom R.D. Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: effect of diazepam. J. Neurosci. 2004, 24:4478-4488.
    • (2004) J. Neurosci. , vol.24 , pp. 4478-4488
    • Galeffi, F.1    Sah, R.2    Pond, B.B.3    George, A.4    Schwartz-Bloom, R.D.5
  • 21
    • 3543148361 scopus 로고    scopus 로고
    • A new model of ischemic preconditioning using young adult hippocampal slice cultures
    • Hassen G.W., Tian D., Ding D., Bergold P.J. A new model of ischemic preconditioning using young adult hippocampal slice cultures. Brain Res. Protoc. 2004, 13:135-143.
    • (2004) Brain Res. Protoc. , vol.13 , pp. 135-143
    • Hassen, G.W.1    Tian, D.2    Ding, D.3    Bergold, P.J.4
  • 22
    • 29144533824 scopus 로고    scopus 로고
    • Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity
    • Holopainen I.E. Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity. Neurochem. Res. 2005, 30:1521-1528.
    • (2005) Neurochem. Res. , vol.30 , pp. 1521-1528
    • Holopainen, I.E.1
  • 24
    • 49049092393 scopus 로고    scopus 로고
    • Development and characterization of an adult retinal explant organotypic tissue culture system as an in vitro intraocular stem cell transplantation model
    • Johnson T.V., Martin K.R. Development and characterization of an adult retinal explant organotypic tissue culture system as an in vitro intraocular stem cell transplantation model. Invest. Ophthalmol. Vis. Sci. 2008, 49:3503-3512.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3503-3512
    • Johnson, T.V.1    Martin, K.R.2
  • 25
    • 67649361953 scopus 로고    scopus 로고
    • Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro
    • Kajta M., Makarewicz D., Zieminska E., Jantas D., Domin H., Lason W., Kutner A., Lazarewicz J.W. Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro. Neurochem. Int. 2009, 55:265-274.
    • (2009) Neurochem. Int. , vol.55 , pp. 265-274
    • Kajta, M.1    Makarewicz, D.2    Zieminska, E.3    Jantas, D.4    Domin, H.5    Lason, W.6    Kutner, A.7    Lazarewicz, J.W.8
  • 26
    • 17144418578 scopus 로고    scopus 로고
    • Presynaptic axonal amyloid-beta induces caspase-3 activation and neurodegeneration in the postsynaptic neuron
    • Kasa P., Papp H., Beke Z., Vadasz D., Zombori J. Presynaptic axonal amyloid-beta induces caspase-3 activation and neurodegeneration in the postsynaptic neuron. Acta Biol. Szeged 2004, 48:1-6.
    • (2004) Acta Biol. Szeged , vol.48 , pp. 1-6
    • Kasa, P.1    Papp, H.2    Beke, Z.3    Vadasz, D.4    Zombori, J.5
  • 27
    • 69349094657 scopus 로고    scopus 로고
    • Evidence for neuroprotection by the fenamate NSAID, mefenamic acid
    • Khansari P.S., Halliwell R.F. Evidence for neuroprotection by the fenamate NSAID, mefenamic acid. Neurochem. Int. 2009, 55:683-688.
    • (2009) Neurochem. Int. , vol.55 , pp. 683-688
    • Khansari, P.S.1    Halliwell, R.F.2
  • 28
    • 18144394140 scopus 로고
    • Oxford University Press, Oxford, J. Cohen, G.P. Wilkin (Eds.)
    • Lillien L. Neural Cell Culture. A Practical Approach 1995, 55-67. Oxford University Press, Oxford. J. Cohen, G.P. Wilkin (Eds.).
    • (1995) Neural Cell Culture. A Practical Approach , pp. 55-67
    • Lillien, L.1
  • 29
    • 0034662989 scopus 로고    scopus 로고
    • Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis
    • Maeno E., Ishizaki Y., Kanaseki T., Hazama A., Okada Y. Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:9487-9492.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 9487-9492
    • Maeno, E.1    Ishizaki, Y.2    Kanaseki, T.3    Hazama, A.4    Okada, Y.5
  • 30
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G., Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am. J. Pathol. 1995, 146:3-15.
    • (1995) Am. J. Pathol. , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 31
    • 0032125488 scopus 로고    scopus 로고
    • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis
    • Martin L.J., Al-Abdulla N.A., Brambrink A.M., Kirsch J.R., Sieber F.E., Portera-Cailliau C. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis. Brain Res. Bull. 1998, 46:281-309.
    • (1998) Brain Res. Bull. , vol.46 , pp. 281-309
    • Martin, L.J.1    Al-Abdulla, N.A.2    Brambrink, A.M.3    Kirsch, J.R.4    Sieber, F.E.5    Portera-Cailliau, C.6
  • 32
    • 0027529578 scopus 로고
    • Time course of synaptic development in hippocampal organotypic cultures
    • Muller D., Buchs P.A., Stoppini L. Time course of synaptic development in hippocampal organotypic cultures. Dev. Brain Res. 1993, 71:93-100.
    • (1993) Dev. Brain Res. , vol.71 , pp. 93-100
    • Muller, D.1    Buchs, P.A.2    Stoppini, L.3
  • 33
    • 33750683984 scopus 로고    scopus 로고
    • Dithranol abolishes UCH-L1 immunoreactivity in the nerve fibers of the rat orofacial skin
    • Orojan I., Szigeti C., Varszegi S., Dobo E., Gulya K. Dithranol abolishes UCH-L1 immunoreactivity in the nerve fibers of the rat orofacial skin. Brain Res. 2006, 1121:216-220.
    • (2006) Brain Res. , vol.1121 , pp. 216-220
    • Orojan, I.1    Szigeti, C.2    Varszegi, S.3    Dobo, E.4    Gulya, K.5
  • 36
    • 78649997930 scopus 로고    scopus 로고
    • The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities
    • (Epub ahead of print)
    • Rohn T.T. The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities. Apoptosis 2010, (Epub ahead of print). 10 1007/s10495-010r-r0463-2.
    • (2010) Apoptosis
    • Rohn, T.T.1
  • 37
    • 0032530577 scopus 로고    scopus 로고
    • Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism
    • Runden E., Seglen P.O., Haug F.M., Ottersen O.P., Wieloch T., Shamloo M., Laake J.H. Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism. J. Neurosci. 1998, 18:7296-7305.
    • (1998) J. Neurosci. , vol.18 , pp. 7296-7305
    • Runden, E.1    Seglen, P.O.2    Haug, F.M.3    Ottersen, O.P.4    Wieloch, T.5    Shamloo, M.6    Laake, J.H.7
  • 38
    • 64949186536 scopus 로고    scopus 로고
    • Diazepam neuroprotection in excitotoxic and oxidative stress involves a mitochondrial mechanism additional to the GABAAR and hypothermic effects
    • Sarnowska A., Beresewicz M., Zablocka B., Domanska-Janik K. Diazepam neuroprotection in excitotoxic and oxidative stress involves a mitochondrial mechanism additional to the GABAAR and hypothermic effects. Neurochem. Int. 2009, 55:164-173.
    • (2009) Neurochem. Int. , vol.55 , pp. 164-173
    • Sarnowska, A.1    Beresewicz, M.2    Zablocka, B.3    Domanska-Janik, K.4
  • 39
    • 54549111959 scopus 로고    scopus 로고
    • The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors
    • Shen H., Yuan Y., Ding F., Liu J., Gu X. The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors. Brain Res. Bull. 2008, 77:274-281.
    • (2008) Brain Res. Bull. , vol.77 , pp. 274-281
    • Shen, H.1    Yuan, Y.2    Ding, F.3    Liu, J.4    Gu, X.5
  • 40
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L., Buchs P.A., Muller D. A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods 1991, 37:173-182.
    • (1991) J. Neurosci. Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 41
    • 61449215012 scopus 로고    scopus 로고
    • Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke
    • Sun M., Zhao Y., Gu Y., Xu C. Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke. Neurochem. Int. 2009, 54:339-346.
    • (2009) Neurochem. Int. , vol.54 , pp. 339-346
    • Sun, M.1    Zhao, Y.2    Gu, Y.3    Xu, C.4
  • 42
    • 77549083105 scopus 로고    scopus 로고
    • Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke
    • Sun M., Zhao Y., Gu Y., Xu C. Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke. Neurochem. Int. 2010, 56:634-641.
    • (2010) Neurochem. Int. , vol.56 , pp. 634-641
    • Sun, M.1    Zhao, Y.2    Gu, Y.3    Xu, C.4
  • 43
    • 0028990125 scopus 로고
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M., Quan T.L., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995, 81:801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, T.L.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 44
    • 0037097439 scopus 로고    scopus 로고
    • Estradiol enhances Akt activation in cortical explant cultures following neuronal injury
    • Wilson M.E., Liu Y., Wise P.M. Estradiol enhances Akt activation in cortical explant cultures following neuronal injury. Mol. Brain Res. 2002, 102:48-54.
    • (2002) Mol. Brain Res. , vol.102 , pp. 48-54
    • Wilson, M.E.1    Liu, Y.2    Wise, P.M.3
  • 47
    • 0037448054 scopus 로고    scopus 로고
    • Neuroprotective effects of bone marrow stromal cells on rat organotypic hippocampal slice culture model of cerebral ischemia
    • Zhong C., Qin Z., Zhong C.-J., Wang Y., Shen X.-Y. Neuroprotective effects of bone marrow stromal cells on rat organotypic hippocampal slice culture model of cerebral ischemia. Neurosci. Lett. 2003, 342:93-96.
    • (2003) Neurosci. Lett. , vol.342 , pp. 93-96
    • Zhong, C.1    Qin, Z.2    Zhong, C.-J.3    Wang, Y.4    Shen, X.-Y.5
  • 48
    • 0034747307 scopus 로고    scopus 로고
    • TGF-β1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures
    • Zhu Y., Ahlemeyer B., Bauerbach E., Krieglstein J. TGF-β1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures. Neurochem. Int. 2001, 38(2001):227-235.
    • (2001) Neurochem. Int. , vol.38 , Issue.2001 , pp. 227-235
    • Zhu, Y.1    Ahlemeyer, B.2    Bauerbach, E.3    Krieglstein, J.4
  • 49
    • 33751190327 scopus 로고    scopus 로고
    • A death-promoting role of extracellular signal-regulated kinase
    • Zhuang S., Schnellmann R.G. A death-promoting role of extracellular signal-regulated kinase. J. Pharm. Exp. Therap. 2006, 319:991-997.
    • (2006) J. Pharm. Exp. Therap. , vol.319 , pp. 991-997
    • Zhuang, S.1    Schnellmann, R.G.2
  • 50
    • 77249122078 scopus 로고    scopus 로고
    • Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
    • Zou J., Wang Y.X., Dou F.F., Lü H.Z., Ma Z.W., Lu P.H., Xu X.M. Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons. Neurochem. Int. 2010, 56:577-584.
    • (2010) Neurochem. Int. , vol.56 , pp. 577-584
    • Zou, J.1    Wang, Y.X.2    Dou, F.F.3    Lü, H.Z.4    Ma, Z.W.5    Lu, P.H.6    Xu, X.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.