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Volumn 83, Issue 3, 2011, Pages 1345-1354

Biodegradable pH-responsive alginate-poly (lactic-co-glycolic acid) nano/micro hydrogel matrices for oral delivery of silymarin

Author keywords

Alginate; Hydrogels; Nanoparticles; Oral drug delivery; Silymarin

Indexed keywords

AFM; ANALYTICAL TECHNIQUES; BIODEGRADABLE CARRIERS; DRYING METHODS; DRYING TECHNIQUE; FTIR; IN-VITRO; MICRO-PARTICLES; MOISTURE CONTENTS; NEW APPROACHES; ORAL DELIVERY; ORAL DRUG DELIVERY; PH VALUE; PH-RESPONSIVE; PH-RESPONSIVE HYDROGELS; POLY(D , L-LACTIC-CO-GLYCOLIC ACID); POLY(LACTIC-CO-GLYCOLIC ACID); SEM; SILYBUM MARIANUM; SILYMARIN; SODIUM ALGINATES; SUSTAINED RELEASE; SWELLING CHARACTERISTICS; UV- AND;

EID: 78650272586     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2010.09.055     Document Type: Article
Times cited : (82)

References (36)
  • 6
    • 0036497985 scopus 로고    scopus 로고
    • Effects of aldehydes and methods of cross-linking on properties of calcium alginate microspheres prepared by emulsification
    • L.W. Chan, and P.W. Heng Effects of aldehydes and methods of cross-linking on properties of calcium alginate microspheres prepared by emulsification Biomaterials 23 2002 1319 1326
    • (2002) Biomaterials , vol.23 , pp. 1319-1326
    • Chan, L.W.1    Heng, P.W.2
  • 7
    • 33646844410 scopus 로고    scopus 로고
    • Optimized preparation of silymarin dripping pills by a central composite design-response surface method
    • W. Chen, H. Xia, and W. Wu Optimized preparation of silymarin dripping pills by a central composite design-response surface method Chinese Traditional Herbal Drug 36 2005 679 683
    • (2005) Chinese Traditional Herbal Drug , vol.36 , pp. 679-683
    • Chen, W.1    Xia, H.2    Wu, W.3
  • 8
    • 77950367760 scopus 로고    scopus 로고
    • Enhanced pH-responsive carrier system based on alginate and chemically modified carboxymethyl chitosan for oral delivery of protein drugs: Preparation and in vitro assessment
    • I.M. El-Sherbiny Enhanced pH-responsive carrier system based on alginate and chemically modified carboxymethyl chitosan for oral delivery of protein drugs: Preparation and in vitro assessment Carbohydrate Polymers 80 2010 1125 1136
    • (2010) Carbohydrate Polymers , vol.80 , pp. 1125-1136
    • El-Sherbiny, I.M.1
  • 9
    • 73949120200 scopus 로고    scopus 로고
    • Preparation and in vitro evaluation of new pH-sensitive hydrogel beads for oral delivery of protein drugs
    • I.M. El-Sherbiny, E.M. Abdel-Bary, and D.R.K. Harding Preparation and in vitro evaluation of new pH-sensitive hydrogel beads for oral delivery of protein drugs Journal of Applied Polymer Science 115 2010 2828 2837
    • (2010) Journal of Applied Polymer Science , vol.115 , pp. 2828-2837
    • El-Sherbiny, I.M.1    Abdel-Bary, E.M.2    Harding, D.R.K.3
  • 10
    • 0032008339 scopus 로고    scopus 로고
    • Milk thistle (Silybum marianum) for the therapy of liver disease
    • DOI 10.1111/j.1572-0241.1998.00139.x, PII S0002927097000828
    • K. Flora, M. Hahn, H. Rosen, and K. Benner Milk thistle (Silybum marianum) for the therapy of liver disease The American Journal of Gastroenterology 93 1998 139 143 (Pubitemid 29063954)
    • (1998) American Journal of Gastroenterology , vol.93 , Issue.2 , pp. 139-143
    • Flora, K.1    Hahn, M.2    Rosen, H.3    Benner, K.4
  • 12
    • 0024745220 scopus 로고
    • N-acetylation in chitosan and the rate of its enzymic hydrolysis
    • S. Hirano, H. Tsuchida, and N. Nagao N-acetylation in chitosan and the rate of its enzymic hydrolysis Biomaterials 10 1989 574 576
    • (1989) Biomaterials , vol.10 , pp. 574-576
    • Hirano, S.1    Tsuchida, H.2    Nagao, N.3
  • 13
    • 14844359964 scopus 로고    scopus 로고
    • Alterations of mast cells and TGF-beta1 on the silymarin treatment for CCl4-induced hepatic fibrosis
    • D.H. Jeong, G.P. Lee, W.I. Jeong, S.H. Do, H.J. Yang, and D.W. Yuan Alterations of mast cells and TGF-beta1 on the silymarin treatment for CCl4-induced hepatic fibrosis World Journal of Gastroenterology 11 2005 1141 1148
    • (2005) World Journal of Gastroenterology , vol.11 , pp. 1141-1148
    • Jeong, D.H.1    Lee, G.P.2    Jeong, W.I.3    Do, S.H.4    Yang, H.J.5    Yuan, D.W.6
  • 14
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • R.A. Jain The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices Biomaterials 21 2000 2475 2490
    • (2000) Biomaterials , vol.21 , pp. 2475-2490
    • Jain, R.A.1
  • 15
    • 0034843656 scopus 로고    scopus 로고
    • Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen α1(I) and TIMP-1
    • DOI 10.1016/S0168-8278(01)00148-9, PII S0168827801001489
    • J.D. Jia, M. Bauer, J.J. Cho, M. Ruehl, S. Milani, and G. Boigk Antifibrotic effect of silymarin in rat secondary biliary fobrosis is mediated by downregulation of procollagen alphal(I)and TIMP-1 Journal of Hepatology 35 2001 392 398 (Pubitemid 32844194)
    • (2001) Journal of Hepatology , vol.35 , Issue.3 , pp. 392-398
    • Jia, J.-D.1    Bauer, M.2    Cho, J.J.3    Ruehl, M.4    Milani, S.5    Boigk, G.6    Riecken, E.O.7    Schuppan, D.8
  • 16
    • 0344687228 scopus 로고    scopus 로고
    • Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1β and prostaglandin E2 synthesis by silymarin
    • J.S. Kang, Y.J. Jeon, S.K. Park, K.H. Yang, and H.M. Kim Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1β and prostaglandin E2 synthesis by silymarin Biochemical Pharmacology 67 2004 175 181
    • (2004) Biochemical Pharmacology , vol.67 , pp. 175-181
    • Kang, J.S.1    Jeon, Y.J.2    Park, S.K.3    Yang, K.H.4    Kim, H.M.5
  • 17
    • 0141974905 scopus 로고    scopus 로고
    • Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum)
    • N.C. Kim, T.N. Graf, C.M. Sparacino, M.C. Wani, and M.E. Wall Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum) Organic Biomolecular Chemistry 1 2003 1684 1689
    • (2003) Organic Biomolecular Chemistry , vol.1 , pp. 1684-1689
    • Kim, N.C.1    Graf, T.N.2    Sparacino, C.M.3    Wani, M.C.4    Wall, M.E.5
  • 18
    • 0033082440 scopus 로고    scopus 로고
    • A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model
    • M. Lahiri-Chatterjee, S.K. Katiyar, R.R. Mohan, and R. Agarwal A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model Cancer Research 59 1999 622 632 (Pubitemid 29076060)
    • (1999) Cancer Research , vol.59 , Issue.3 , pp. 622-632
    • Lahiri-Chatterjee, M.1    Katiyar, S.K.2    Mohan, R.R.3    Agarwal, R.4
  • 19
    • 11244259256 scopus 로고    scopus 로고
    • Effects of alginate coated on PLGA microspheres for delivery tetracycline hydrochloride to periodontal pockets
    • D.Z. Liu, W.P. Chen, C.P. Lee, S.L. Wu, Y.C. Wang, and T.W. Chung Effects of alginate coated on PLGA microspheres for delivery tetracycline hydrochloride to periodontal pockets Journal of Microencapsulation 21 2004 643 652
    • (2004) Journal of Microencapsulation , vol.21 , pp. 643-652
    • Liu, D.Z.1    Chen, W.P.2    Lee, C.P.3    Wu, S.L.4    Wang, Y.C.5    Chung, T.W.6
  • 20
    • 33751224468 scopus 로고    scopus 로고
    • Novel polymeric microspheres containing norcantharidin for chemoembolization
    • DOI 10.1016/j.jconrel.2006.08.022, PII S0168365906004275
    • X. Liu, W.S.H. Paul, Q. Li, and L.W. Chan Novel polymeric microspheres containing norcantharidin for chemoembolization Journal of Controlled Release 116 2006 35 41 (Pubitemid 44792296)
    • (2006) Journal of Controlled Release , vol.116 , Issue.1 , pp. 35-41
    • Liu, X.1    Heng, W.S.2    Paul3    Li, Q.4    Chan, L.W.5
  • 21
    • 0032239998 scopus 로고    scopus 로고
    • A Review of Plants Used in the Treatment of Liver Disease: Part 1
    • S. Luper A review of plants used in the treatment of liver disease: Part 1 Alternative Medicine Review 3 1998 410 421 (Pubitemid 128709687)
    • (1998) Alternative Medicine Review , vol.3 , Issue.6 , pp. 410-421
    • Luper, S.1
  • 23
    • 0028956461 scopus 로고
    • Silybum marianum (Carduus marianus)
    • P. Morazzoni, and E. Bombardelli Silybum marianum (Carduus marianus) Fitoterapia 46 1995 3 42
    • (1995) Fitoterapia , vol.46 , pp. 3-42
    • Morazzoni, P.1    Bombardelli, E.2
  • 26
    • 33847369164 scopus 로고    scopus 로고
    • Handling and processing of food powders and particulates
    • E. Ortega-Rivas Handling and processing of food powders and particulates C. Onwulata, Encapsulated and powdered foods 2005 CRC Press, Taylor & Francis G. Boca Raton 78 81
    • (2005) Encapsulated and Powdered Foods , pp. 78-81
    • Ortega-Rivas, E.1
  • 28
    • 0026776782 scopus 로고
    • Pharmacokinetics of silybin in bile following administration of silipide and silymarin in cholecystectomy patients
    • R. Schandalik, G. Gatti, and E. Perucca Pharmacokinetics of silybin in bile following administration of silipide and silymarin in cholecystectomy patients Arzneimittelforschung 42 1992 964 968
    • (1992) Arzneimittelforschung , vol.42 , pp. 964-968
    • Schandalik, R.1    Gatti, G.2    Perucca, E.3
  • 29
    • 0031947695 scopus 로고    scopus 로고
    • Inhibition of xanthine oxidase by purpurogallin and silymarin group
    • S.Y. Sheu, C.H. Lai, and H.C. Chiang Inhibition of xanthine oxidase by purpurogallin and silymarin group Anticancer Research 18 1998 263 267
    • (1998) Anticancer Research , vol.18 , pp. 263-267
    • Sheu, S.Y.1    Lai, C.H.2    Chiang, H.C.3
  • 32
    • 0344958777 scopus 로고    scopus 로고
    • Polymeric micelles as carriers of diagnostic agents
    • DOI 10.1016/S0169-409X(98)00100-8, PII S0169409X98001008
    • V.S. Trubetskoy Polymeric micelles as carriers of diagnostic agents Advanced Drug Delivery Reviews 37 1999 81 88 (Pubitemid 29164501)
    • (1999) Advanced Drug Delivery Reviews , vol.37 , Issue.1-3 , pp. 81-88
    • Trubetskoy, V.S.1
  • 33
    • 33646854907 scopus 로고    scopus 로고
    • Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system
    • DOI 10.1016/j.ejpb.2005.12.005, PII S0939641105003383
    • W. Wu, Y. Wang, and L. Que Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system European Journal of Pharmaceutics and Biopharmaceutics 63 2006 288 294 (Pubitemid 43776222)
    • (2006) European Journal of Pharmaceutics and Biopharmaceutics , vol.63 , Issue.3 , pp. 288-294
    • Wu, W.1    Wang, Y.2    Que, L.3
  • 34
    • 25144447412 scopus 로고    scopus 로고
    • Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis
    • DOI 10.1016/j.ijantimicag.2005.07.012, PII S0924857905002050
    • A. Zahoor, S. Sharma, and G.K. Khuller Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis International Journal of Antimicrobial Agents 26 2005 298 303 (Pubitemid 41338657)
    • (2005) International Journal of Antimicrobial Agents , vol.26 , Issue.4 , pp. 298-303
    • Zahoor, A.1    Sharma, S.2    Khuller, G.K.3
  • 35
    • 0031921546 scopus 로고    scopus 로고
    • 1 arrest through an increase in Cipl/p21 concomitant with a decrease in kinase activity of cyclin- dependent kinases and associated cyclins
    • X. Zi, D.K. Feyes, and R. Agarwal Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: Induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins Clinical Cancer Research 4 1998 1055 1064 (Pubitemid 28183409)
    • (1998) Clinical Cancer Research , vol.4 , Issue.4 , pp. 1055-1064
    • Zi, X.1    Feyes, D.K.2    Agarwal, R.3
  • 36
    • 0032080609 scopus 로고    scopus 로고
    • 1
    • X. Zi, A.W. Grasso, H.J. Kung, and R. Agarwal A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells Cancer Research 58 1998 1920 1929 (Pubitemid 28217468)
    • (1998) Cancer Research , vol.58 , Issue.9 , pp. 1920-1929
    • Zi, X.1    Grasso, A.W.2    Kung, H.-J.3    Agarwal, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.