Inhibition of xanthine oxidase by purpurogallin and silymarin group

Anticancer Research

Volumn 18, Issue 1 A, 1998, Pages 263-267

  Sheu, Shiow Yunn ^a   Lai, Chih Hao ^b   Chiang, Hsüch Ching ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Antihepatotoxic principle; Antitumor; Phenolic compounds; Purpurogallin; Silymarin group; Xanthine oxidase inhibitors

Indexed keywords

HYPOXANTHINE; PURPUROGALLIN; SILYMARIN; UNCLASSIFIED DRUG; URIC ACID; XANTHINE; XANTHINE OXIDASE; XANTHINE OXIDASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; OXIDATION; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ANTIOXIDANTS; BENZOCYCLOHEPTENES; CELL-FREE SYSTEM; ENZYME INHIBITORS; KINETICS; PHENOLS; SILYMARIN; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHINE OXIDASE;

EID: 0031947695     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Chang WS, Lee YJ, Lu FJ and Chiang HC: Inhibitory effects of flavonoids on xanthine oxidase. Anticancer Res 13: 2165-2170, 1993.
2. Chang WS, Chang YH, Lu FJ and Chiang HC: Inhibitory effects of phenolics on xanthine oxidase. Anticancer Res 14: 501-506, 1994.
3. Chang WS, Wen PC and Chinag HC: Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition. Anticancer Res 15: 703-708, 1995.
4. Chang WS and Chiang HC: Structure-activity relationship of coumarins in xanthine oxidase inhibition. Anticancer Res 15: 1969-1974, 1995.
5. Chang WS, Yan GF and Chiang HC: Inhibitory effects of phenolic carboxylic acid analogues on xanthine oxidase. Anticancer Res 15: 2097-2100, 1995.
6. Chiang HC, Lo YJ and Lu FJ: Xanthine oxidase inhibitors from the leaves of Alsophila spinulosa (Hook) Tryon. J Enzyme Inhibit 8(1): 61-71, 1994.
7. Sheu SY and Chiang HC: Inhibitory effects of plant growth regulators on xanthine oxidase. Anticancer Res 16: 311-315, 1996.
8. Sheu SY, Lin YC and Chiang HC: Inhibition of xanhtine oxidase by cytokinins and related substances. Anticancer Res 16: 3571-3576, 1996.
9. Sheu SY, Lin YC and Chiang HC: Inhibition of xanthine oxidase by synthetic cytokinin analogues. Anticancer Res 17: 1043-1050, 1997.
10. Colowick SP and Kaplan NO: Methods in Enzymology. Vol. 74. Immunochemical Techniques. Part C edited by Langone JJ and Vanakis HV. In: (Halfman CJ ed), Section II. Data analysis. Chapter 32. Concentrations of binding proteins and labeled analyte that are appropriate for measuring at any analyte concentration range in radioimmunoassays. pp. 481-497, and (Ukraincik K and Piknosh W eds), Chapter 33, Microprocessor-based radioimmunoassay data analysis. New York; Academic Press Inc 1981, pp.497-508.
11. Colowick SP and Kaplan NO: Methods in Enzymology. Vol. 74. Immunochemical Techniques. Part C edited by Langone JJ and Vanakis HV. In: (Halfman CJ ed), Section II. Data analysis. Chapter 32. Concentrations of binding proteins and labeled analyte that are appropriate for measuring at any analyte concentration range in radioimmunoassays. pp. 481-497, and (Ukraincik K and Piknosh W eds), Chapter 33, Microprocessor-based radioimmunoassay data analysis. New York; Academic Press Inc 1981, pp.497-508.
12. Lineweaver H and Burk D: The determination of enzyme dissociation constants. J Am Chem Soc 56: 658-666, 1934.
13. Segel IH: Biochemical Calculations. 2nd ed. In: Chapter 4. Enzyme. Enzyme inhibition, p. 250, competitive inhibition; p. 260, uncompetitive inhibition; p. 261, mixed type inhibition. New York, John Wiley and Sons, 1976.
14. Wu TW, Zeng LH, Fung KP, Richard D Weisel, Andrew Temple and Norman Camerman: Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells. Biochem Pharmacol 52: 1073-1080, 1996.
15. Fung KP, WU TW and Lui CP: Purpurogallinm inhibits DNA synthesis of murine fibrosarcoma L-929 and U-87MG glioblastoma cell in vitro. Chemotherapy 42: 199-205, 1996.
16. Rootman DS, Bindish R, Zeng LH, Hasany SM and Wu TW: Purpurogallin as a cytoprotector of cultured rabbit corneal endothelium. Can J Ophthalmol 29: 220-223, 1994.
17. Sugiyama H, Fung KP and Wu TW: Purpurogallin, as an antioxidant protector of human erythrocytes against lysis by peroxyl radicals. Life Sci 53: PL39-43, 1993.
18. Wu TW, Wu J, Zeng LH, Au JX, Carey D and Fung KP: Purpurogallin: in vivo evidence of a novel and effective cardioprotector. Life Sei 54: PL23-28, 1994.
19. th edition. pp.8283, 1976 or Aldrich 25492-4.
20. Sanhueza J, Valdes J, Campos R, Garrido A and Valenzuela A: Changes in the xanthine dehydrogenase/ xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress. Res Comms in Chem Pathol Pharmacol 78: 211-218, 1992.
21. Greimel A and Koch H: Silymarin- an inhibitor of horseradish peroxidase. Experientia 33: 1417-1418, 1977.
22. Fiebrich F and Koch H: Silymarin, an inhibitor of lipoxygenase. Experientia 35: 1548-1550, 1979.
23. Fiebrich F and Koch H: Silymarin, an inhibitor of prostaglandin synthetase. Experientia 35: 1550-1552, 1979.
24. Al-Khalidi UAS and Geha RS: The sensitivity of serum xanthine oxidase and serum glutamic pyruvic transaminase in detecting liver damage. Clin Chim Acta 14: 833-835, 1966
25. Shamma'A MH, Nasrallah S, Chaglassian T, Kachadurian AK and Al-khalidi UAS: Serum xanthine oxidase: A sensitive test of acute liver injury. Gastroenterology 48: 226-230, 1965.
26. Ramboer CRH: A sensitive and nonradioactive assay for serum and tissue xanthine oxidase. J Lab and Clin Med 74: 828-835, 1969.
27. Chan PH, Schimidley JW, Fishman RA and Longar SM: Brain injury, edema and vascular permeability changes induced by oxygen-derived free radicals. Neurology, 34: 315-320, 1984.
28. Elks J and Ganellin CR: Dictionary of Drugs. P.1100, S-00069-S-00071. London and New York Chapman and Hall, 1990.