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Volumn 58, Issue 9, 1998, Pages 1920-1929

A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells1

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; SILYMARIN;

EID: 0032080609     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (187)

References (75)
  • 1
    • 0029849017 scopus 로고    scopus 로고
    • Essential fatty acids and prostate cancer: An emerging hypothesis?
    • Hsing, A. W. Essential fatty acids and prostate cancer: an emerging hypothesis? Cancer Epidemiol. Biomark. Prev., 5: 859-860, 1996.
    • (1996) Cancer Epidemiol. Biomark. Prev. , vol.5 , pp. 859-860
    • Hsing, A.W.1
  • 4
    • 0028774982 scopus 로고
    • Do diet and androgens alter prostate cancer risk via a common etiologic pathway?
    • Ross, R. K., and Henderson, B. E. Do diet and androgens alter prostate cancer risk via a common etiologic pathway? J. Natl. Cancer Inst., 86: 252-254, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 252-254
    • Ross, R.K.1    Henderson, B.E.2
  • 7
    • 0027981518 scopus 로고
    • Nutrition and prostate cancer: A proposal for dietary intervention
    • Wynder, E. L., Rose, D. P., and Cohen, L. A. Nutrition and prostate cancer: a proposal for dietary intervention. Nutr. Cancer, 22: 1-10, 1994.
    • (1994) Nutr. Cancer , vol.22 , pp. 1-10
    • Wynder, E.L.1    Rose, D.P.2    Cohen, L.A.3
  • 8
    • 0029753765 scopus 로고    scopus 로고
    • Prostate cancer prevention: Investigational approaches and opportunities
    • Karp, J. E., Chiarodo, A., Brawley, O., and Kelloff, G. J. Prostate cancer prevention: investigational approaches and opportunities. Cancer Res., 56: 5547-5556, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 5547-5556
    • Karp, J.E.1    Chiarodo, A.2    Brawley, O.3    Kelloff, G.J.4
  • 9
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Washington DC
    • Levitzki, A., and Gazit, A. Tyrosine kinase inhibition: an approach to drug development. Science (Washington DC), 267: 1782-1788, 1995.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 11
    • 0028762944 scopus 로고
    • c-erbB-2 oncogene expression in proslatic intraepithelial neoplasia: Mounting evidence for a precursor role
    • Bostwick, D. G. c-erbB-2 oncogene expression in proslatic intraepithelial neoplasia: mounting evidence for a precursor role. J. Natl. Cancer Inst., 86: 1108-1110, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1108-1110
    • Bostwick, D.G.1
  • 12
    • 0028170155 scopus 로고
    • Expression of p160erbB3 and p185erbB2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    • Myers, R. B., Srivastava, S., Oelschlager, D. K., and Grizzle, W. E. Expression of p160erbB3 and p185erbB2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. J. Natl. Cancer Inst., 86: 1140-1145, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1140-1145
    • Myers, R.B.1    Srivastava, S.2    Oelschlager, D.K.3    Grizzle, W.E.4
  • 13
    • 0002633382 scopus 로고
    • Biochemistry of prostatic carcinoma
    • T. G. Pretlow and T. P. Pretlow (eds.), San Diego: Academic Press
    • Pretlow, T. G., Pelley, R. J., and Pretlow, T. P. Biochemistry of prostatic carcinoma. In: T. G. Pretlow and T. P. Pretlow (eds.), Biochemical and Molecular Aspects of Selected Cancers, pp. 169-237, San Diego: Academic Press, 1994.
    • (1994) Biochemical and Molecular Aspects of Selected Cancers , pp. 169-237
    • Pretlow, T.G.1    Pelley, R.J.2    Pretlow, T.P.3
  • 14
    • 0030513962 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia (PIN) and other prostatic lesions as risk factors and surrogate endpoints for cancer chemoprevention trials
    • Bostwick, D. G., and Aquilina, J. W. Prostatic intraepithelial neoplasia (PIN) and other prostatic lesions as risk factors and surrogate endpoints for cancer chemoprevention trials. J. Cell. Biochem., 25 (Suppl.): 156-164, 1996.
    • (1996) J. Cell. Biochem. , vol.25 , Issue.SUPPL. , pp. 156-164
    • Bostwick, D.G.1    Aquilina, J.W.2
  • 15
    • 0027481970 scopus 로고
    • Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer
    • Ware, J. L. Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer. Cancer Metastasis Rev., 12: 287-301, 1993.
    • (1993) Cancer Metastasis Rev. , vol.12 , pp. 287-301
    • Ware, J.L.1
  • 16
    • 0025773426 scopus 로고
    • Autonomous growth of androgen-independent human prostatic carcinoma cells: Role of transforming growth factor α
    • Hofer, D. R., Sherwood, E. R., Bromberg, W. D., Mendelsohn, J., Lee, C., and Kozlowski, J. M. Autonomous growth of androgen-independent human prostatic carcinoma cells: role of transforming growth factor α. Cancer Res., 51: 2780-2785, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 2780-2785
    • Hofer, D.R.1    Sherwood, E.R.2    Bromberg, W.D.3    Mendelsohn, J.4    Lee, C.5    Kozlowski, J.M.6
  • 17
    • 0026453540 scopus 로고
    • Epidermal growth factor receptor monoclonal antibody inhibits constitutive receptor phosphorylation, reduces autonomous growth, and sensitizes androgen-independent prostatic carcinoma cells to tumor necrosis factor α
    • Fong, C. J., Sherwood, E. R., Mendelsohn, J., Lee, C., and Kozlowski, J. M. Epidermal growth factor receptor monoclonal antibody inhibits constitutive receptor phosphorylation, reduces autonomous growth, and sensitizes androgen-independent prostatic carcinoma cells to tumor necrosis factor α. Cancer Res., 52: 5887-5892, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 5887-5892
    • Fong, C.J.1    Sherwood, E.R.2    Mendelsohn, J.3    Lee, C.4    Kozlowski, J.M.5
  • 20
    • 0025021731 scopus 로고
    • Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials
    • Boone, C. W., Kelloff, G. J., and Malone, W. E. Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials. Cancer Res., 50: 2-9, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2-9
    • Boone, C.W.1    Kelloff, G.J.2    Malone, W.E.3
  • 21
    • 0028340482 scopus 로고
    • Current strategies of cancer chemoprevention: 13th Sapporo Cancer Seminar
    • Boone, C. W., and Wattenberg, L. W. Current strategies of cancer chemoprevention: 13th Sapporo Cancer Seminar. Cancer Res., 54: 3315-3318, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3315-3318
    • Boone, C.W.1    Wattenberg, L.W.2
  • 22
    • 0026590679 scopus 로고
    • Inhibition of carcinogenesis by minor dietary constituents
    • Wattenberg, L. W. Inhibition of carcinogenesis by minor dietary constituents. Cancer Res., 52 (Suppl.): 2085s-2091s, 1992.
    • (1992) Cancer Res. , vol.52 , Issue.SUPPL.
    • Wattenberg, L.W.1
  • 23
    • 0027527396 scopus 로고
    • Cancer chemoprevention: Principles and prospects
    • Lond.
    • Morse, M. A., and Stoner, G. D. Cancer chemoprevention: principles and prospects. Carcinogenesis (Lond.), 14: 1737-1746, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1737-1746
    • Morse, M.A.1    Stoner, G.D.2
  • 26
    • 0027033606 scopus 로고
    • Chemoprevention of premalignant and early malignant lesions of the prostate
    • Bostwick, D. G., Scardino, P. T., Kelloff, G. J., and Boone, C. W. Chemoprevention of premalignant and early malignant lesions of the prostate. J. Cell. Biochem. Suppl., 16H: 1-145, 1992.
    • (1992) J. Cell. Biochem. Suppl. , vol.16 H , pp. 1-145
    • Bostwick, D.G.1    Scardino, P.T.2    Kelloff, G.J.3    Boone, C.W.4
  • 27
    • 1942487575 scopus 로고
    • Qualitative pathology in chemoprevention trails: Standardization and quality control of surrogate endpoint biomarker assays for colon, breast, and prostate
    • Boone, C. W., and Kelloff, G. J. Qualitative pathology in chemoprevention trails: standardization and quality control of surrogate endpoint biomarker assays for colon, breast, and prostate. J. Cell. Biochem. Suppl., 19: 1-294, 1994.
    • (1994) J. Cell. Biochem. Suppl. , vol.19 , pp. 1-294
    • Boone, C.W.1    Kelloff, G.J.2
  • 29
    • 0028906653 scopus 로고
    • Chemoprevention for prostate cancer
    • Brawer, M. K., and Ellis, W. J. Chemoprevention for prostate cancer. Cancer (Phila.) Suppl., 75: 1783-1789, 1995.
    • (1995) Cancer (Phila.) Suppl. , vol.75 , pp. 1783-1789
    • Brawer, M.K.1    Ellis, W.J.2
  • 31
    • 0025811591 scopus 로고
    • Protection against microcystin-LR-induced hepatotoxicity by silymarin: Biochemistry, histopathology, and lethality
    • Mereish, K. A., Bunner, D. L., Ragland, D. R., and Creasia, D. A. Protection against microcystin-LR-induced hepatotoxicity by silymarin: biochemistry, histopathology, and lethality. Pharmacol. Res., 8: 273-277, 1991.
    • (1991) Pharmacol. Res. , vol.8 , pp. 273-277
    • Mereish, K.A.1    Bunner, D.L.2    Ragland, D.R.3    Creasia, D.A.4
  • 32
    • 0025310518 scopus 로고
    • Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice
    • Letteron, P., Labbe, G., Degott, C., Berson, A., Fromenty, B., Delaforge, M., Larrey, D., and Pessayre, D. Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice. Biochem. Pharmacol., 39: 2027-2034, 1990.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 2027-2034
    • Letteron, P.1    Labbe, G.2    Degott, C.3    Berson, A.4    Fromenty, B.5    Delaforge, M.6    Larrey, D.7    Pessayre, D.8
  • 35
    • 0016433509 scopus 로고
    • Studies on the pharmacodynamics, including site and mode of action, of silymarin: The antihepatotoxic principle from Silybum mar. (L) Gaertn
    • Vogel, G., Trost, W., and Braatz, R. Studies on the pharmacodynamics, including site and mode of action, of silymarin: the antihepatotoxic principle from Silybum mar. (L) Gaertn. Arzneim. Forsch., 25: 82-89, 1975.
    • (1975) Arzneim. Forsch. , vol.25 , pp. 82-89
    • Vogel, G.1    Trost, W.2    Braatz, R.3
  • 36
    • 0014294313 scopus 로고
    • Pharmacology and toxicology of silymarin, the anti-hepatotoxic agent of Silybum marianum (L.) Gaertn
    • Hahn, V. G., Lehmann, H. D., Kurten, M., Uebel, H., and Vogel, G. Pharmacology and toxicology of silymarin, the anti-hepatotoxic agent of Silybum marianum (L.) Gaertn. Arzneim. Forsch., 18: 698-704, 1968.
    • (1968) Arzneim. Forsch. , vol.18 , pp. 698-704
    • Hahn, V.G.1    Lehmann, H.D.2    Kurten, M.3    Uebel, H.4    Vogel, G.5
  • 37
    • 0024552331 scopus 로고
    • Dermatologic therapies you've probably never heard of
    • Ely, H. Dermatologic therapies you've probably never heard of. Derm. Clinics, 7: 19-35, 1989.
    • (1989) Derm. Clinics , vol.7 , pp. 19-35
    • Ely, H.1
  • 38
    • 0014295202 scopus 로고
    • The chemistry of silymarin (silybin), the active principle of the fruits of Silybum marianum (L.) Gaertn (Carduus marianus (L))
    • Wagner, H., Seligmann, O., Horhammer, L., and Munster, R. The chemistry of silymarin (silybin), the active principle of the fruits of Silybum marianum (L.) Gaertn (Carduus marianus (L)). Arzneim. Forsch., 18: 688-696, 1968.
    • (1968) Arzneim. Forsch. , vol.18 , pp. 688-696
    • Wagner, H.1    Seligmann, O.2    Horhammer, L.3    Munster, R.4
  • 39
    • 0026532350 scopus 로고
    • Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes
    • Bosisio, E., Benelli, C., and Pirola, O. Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. Pharmacol. Res., 25: 147-154, 1992.
    • (1992) Pharmacol. Res. , vol.25 , pp. 147-154
    • Bosisio, E.1    Benelli, C.2    Pirola, O.3
  • 40
    • 0026643016 scopus 로고
    • Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016
    • Carini, R., Comoglio, A., Albano, E., and Poli, G. Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016. Biochem. Pharmacol., 43: 2111-2115, 1992.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 2111-2115
    • Carini, R.1    Comoglio, A.2    Albano, E.3    Poli, G.4
  • 41
    • 0025190226 scopus 로고
    • An antioxidant drug, silibinin, modulates steroid secretion in human pathological adrenocortical cells
    • Racz, K., Feher, J., Csomos, G., Varga, I., Kiss, R., and Glaz, E. An antioxidant drug, silibinin, modulates steroid secretion in human pathological adrenocortical cells. J. Endocrinol., 124: 341-345, 1990.
    • (1990) J. Endocrinol. , vol.124 , pp. 341-345
    • Racz, K.1    Feher, J.2    Csomos, G.3    Varga, I.4    Kiss, R.5    Glaz, E.6
  • 42
    • 0022872988 scopus 로고
    • Antioxidant properties of the flavonoids silybin and (+)-cyanidanol-3: Comparison with butylated hydroxyanisole and butylated hydroxytoluene
    • Valenzuela, A., Guerra, R., and Videla, L. A. Antioxidant properties of the flavonoids silybin and (+)-cyanidanol-3: comparison with butylated hydroxyanisole and butylated hydroxytoluene. Planta Med., 5: 438-440, 1986.
    • (1986) Planta Med. , vol.5 , pp. 438-440
    • Valenzuela, A.1    Guerra, R.2    Videla, L.A.3
  • 44
    • 0026006786 scopus 로고
    • Effect of the bioflavonoid silymarin on the in vitro activity and expression of superoxide dismutase (SOD) enzyme
    • Muzes, G., Deak, G., Lang, I., Nekam, K., Gergely, P., and Feher, J. Effect of the bioflavonoid silymarin on the in vitro activity and expression of superoxide dismutase (SOD) enzyme. Acta Phys. Hung., 78: 3-9, 1991.
    • (1991) Acta Phys. Hung. , vol.78 , pp. 3-9
    • Muzes, G.1    Deak, G.2    Lang, I.3    Nekam, K.4    Gergely, P.5    Feher, J.6
  • 45
    • 0028283883 scopus 로고
    • Inhibitory effect of silymarin, an anti-hepatotoxic flavonoid, on 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and mRNA in SENCAR mice
    • Lond.
    • Agarwal, R., Katiyar, S. K., Lundgren, D. W., and Mukhtar, H. Inhibitory effect of silymarin, an anti-hepatotoxic flavonoid, on 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and mRNA in SENCAR mice. Carcinogenesis (Lond.), 15: 1099-1103, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1099-1103
    • Agarwal, R.1    Katiyar, S.K.2    Lundgren, D.W.3    Mukhtar, H.4
  • 46
    • 0030903321 scopus 로고    scopus 로고
    • Protective effects of silymarin against photocarcinogenesis in mouse skin model
    • Katiyar, S. K., Korman, N. J., Mukhtar, H., and Agarwal, R. Protective effects of silymarin against photocarcinogenesis in mouse skin model. J. Natl. Cancer Inst., 89: 556-566, 1997.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 556-566
    • Katiyar, S.K.1    Korman, N.J.2    Mukhtar, H.3    Agarwal, R.4
  • 47
    • 0031561420 scopus 로고    scopus 로고
    • Novel cancer chemopreventive effects of a flavonoid antioxidant silymarin: Inhibition of mRNA expression of an endogenous tumor promoter TNFα
    • Zi, X., Mukhtar, H., and Agarwal, R. Novel cancer chemopreventive effects of a flavonoid antioxidant silymarin: inhibition of mRNA expression of an endogenous tumor promoter TNFα. Biochem. Biophys. Res. Commun., 239: 334-339, 1997.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 334-339
    • Zi, X.1    Mukhtar, H.2    Agarwal, R.3
  • 48
    • 0025741216 scopus 로고
    • Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol
    • Mehta, R. G., and Moon, R. C. Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol. Anticancer Res., 11: 593-596, 1991.
    • (1991) Anticancer Res. , vol.11 , pp. 593-596
    • Mehta, R.G.1    Moon, R.C.2
  • 50
    • 0030597239 scopus 로고    scopus 로고
    • Three paths of stress relief
    • Canman, C. E., and Kastan, M. B. Three paths of stress relief. Nature (Lond.), 384: 213-214, 1996.
    • (1996) Nature (Lond.) , vol.384 , pp. 213-214
    • Canman, C.E.1    Kastan, M.B.2
  • 51
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Washington DC
    • Rosette, C., and Karin, M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science (Washington DC), 274: 1194-1197, 1996.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 53
    • 0025321157 scopus 로고
    • Epidermal growth factor
    • Carpenter, G., and Cohen, S. Epidermal growth factor. J. Biol. Chem., 265: 7709-7712, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7709-7712
    • Carpenter, G.1    Cohen, S.2
  • 54
    • 0029834929 scopus 로고    scopus 로고
    • Involvement of SHC, GRB2, SOS and RAS in prolactin signal transduction in mammary epithelial cells
    • Das, R., and Vonderhaar, B. K. Involvement of SHC, GRB2, SOS and RAS in prolactin signal transduction in mammary epithelial cells. Oncogene, 13: 1139-1145, 1996.
    • (1996) Oncogene , vol.13 , pp. 1139-1145
    • Das, R.1    Vonderhaar, B.K.2
  • 55
    • 0029809187 scopus 로고    scopus 로고
    • N-Shc: A neural-specific adapter molecule that mediates signaling from neurotrophin/ Trk to Ras/MAPK pathway
    • Nakamura, T., Sanokawa, R., Sasaki, Y., Ayusawa, D., Oishi, M., and Mori, N. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/ Trk to Ras/MAPK pathway. Oncogene, 13: 1111-1121, 1996.
    • (1996) Oncogene , vol.13 , pp. 1111-1121
    • Nakamura, T.1    Sanokawa, R.2    Sasaki, Y.3    Ayusawa, D.4    Oishi, M.5    Mori, N.6
  • 56
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter, T., and Pines, J. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell, 79: 573-582, 1994.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 57
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D. O. Principles of CDK regulation. Nature (Lond.), 374: 131-134, 1995.
    • (1995) Nature (Lond.) , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 58
    • 0029664395 scopus 로고    scopus 로고
    • Regulation of p21WAF1/ CIP1 expression through mitogen-activated protein kinase signaling pathway
    • Liu, Y., Martindale, J. L., Gorospe, M., and Holbrook, N. J. Regulation of p21WAF1/ CIP1 expression through mitogen-activated protein kinase signaling pathway. Cancer Res., 56: 31-35, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 31-35
    • Liu, Y.1    Martindale, J.L.2    Gorospe, M.3    Holbrook, N.J.4
  • 59
    • 0030614514 scopus 로고    scopus 로고
    • WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells
    • WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. Cancer Res., 57: 320-325, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 320-325
    • Blagosklonny, M.V.1    Prabhu, N.S.2    El-Deiry, W.S.3
  • 60
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs)
    • Grana, X., and Reddy, P. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs). Oncogene, 11: 211-219, 1995.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, P.2
  • 61
    • 0029456024 scopus 로고
    • Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer
    • Barnes, S., Peterson, T. G., and Coward, L. Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer. J. Cell. Biochem. Suppl., 22: 181-187, 1995.
    • (1995) J. Cell. Biochem. Suppl. , vol.22 , pp. 181-187
    • Barnes, S.1    Peterson, T.G.2    Coward, L.3
  • 62
    • 0028216956 scopus 로고
    • Soy intake and cancer risk: A review of the in vitro and in vivo data
    • Messina, M. J., Persky, V., Setchell, K. D. R., and Barnes, S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr. Cancer, 21: 113-131, 1994.
    • (1994) Nutr. Cancer , vol.21 , pp. 113-131
    • Messina, M.J.1    Persky, V.2    Setchell, K.D.R.3    Barnes, S.4
  • 63
    • 0029859580 scopus 로고    scopus 로고
    • Human prostate tumor growth in athymic mice: Inhibition by androgens and stimulation by finasteride
    • Umekita, Y., Hiipakka, R. A., Kokontis, J. M., and Liao, S. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride. Proc. Natl. Acad. Sci. USA, 93: 11802-11807, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11802-11807
    • Umekita, Y.1    Hiipakka, R.A.2    Kokontis, J.M.3    Liao, S.4
  • 64
    • 0031020769 scopus 로고    scopus 로고
    • Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells
    • Ripple, M. O., Henry, W. F., Rago, R. P., and Wilding, G. Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells. J. Natl. Cancer Inst., 89: 40-48, 1997.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 40-48
    • Ripple, M.O.1    Henry, W.F.2    Rago, R.P.3    Wilding, G.4
  • 65
    • 0030967371 scopus 로고    scopus 로고
    • Androgen deprivation as a strategy for prostate cancer chemoprevention
    • Aquilina, J. W., Lipsky, J. J., and Bostwick, D. G. Androgen deprivation as a strategy for prostate cancer chemoprevention. J. Natl. Cancer Inst., 89: 689-696, 1997.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 689-696
    • Aquilina, J.W.1    Lipsky, J.J.2    Bostwick, D.G.3
  • 66
    • 0025045495 scopus 로고
    • Androgen receptor gene expression in human prostate carcinoma cell lines
    • Tilley, W. D., Wilson, C. M., Marcelli, M., and McPhaul, M. J. Androgen receptor gene expression in human prostate carcinoma cell lines. Cancer Res., 50: 5382-5386, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 5382-5386
    • Tilley, W.D.1    Wilson, C.M.2    Marcelli, M.3    McPhaul, M.J.4
  • 67
    • 0029049891 scopus 로고
    • Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor α in the progression of prostatic neoplasms
    • Scher, H., Sarkis, A., Reuter, V., Cohen, D., Netto, G., Petrylak, D., Lianes, P., Fuks, Z., Mendelsohn, J., and Cordon-Cardo, C. Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor α in the progression of prostatic neoplasms. Clin. Cancer Res., 1: 545-550, 1995.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 545-550
    • Scher, H.1    Sarkis, A.2    Reuter, V.3    Cohen, D.4    Netto, G.5    Petrylak, D.6    Lianes, P.7    Fuks, Z.8    Mendelsohn, J.9    Cordon-Cardo, C.10
  • 68
    • 0030337951 scopus 로고    scopus 로고
    • Relevance of cyclin D1 and other molecular markers to cancer chemoprevention
    • Weinstein, I. B. relevance of cyclin D1 and other molecular markers to cancer chemoprevention. J. Cell. Biochem., 25S: 23-28, 1996.
    • (1996) J. Cell. Biochem. , vol.25 S , pp. 23-28
    • Weinstein, I.B.1
  • 69
    • 0025033793 scopus 로고
    • Cell cycle control in eukaryotes: Molecular mechanisms of cdc2 activation
    • Draetta, G. Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation. Trends Biochem. Sci., 15: 378-383, 1990.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 378-383
    • Draetta, G.1
  • 70
    • 0025090934 scopus 로고
    • Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B
    • Pines, J., and Hunter, T. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (Lond.), 346: 760-763, 1990.
    • (1990) Nature (Lond.) , vol.346 , pp. 760-763
    • Pines, J.1    Hunter, T.2
  • 71
    • 0028171292 scopus 로고
    • 1 phase progression: Cycling on cue
    • 1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.