Polymeric micelles as carriers of diagnostic agents

Advanced Drug Delivery Reviews

Volumn 37, Issue 1-3, 1999, Pages 81-88

  Trubetskoy, Vladimir S ^a  

^a Mirus Bio Corporation   (United States)

Author keywords

Amphiphilic block copolymers; Contrast agents; Drug carriers; Imaging; Micelles; Particulates

Indexed keywords

AGENTS; BLOCK COPOLYMERS; COMPUTERIZED TOMOGRAPHY; CONTROLLED DRUG DELIVERY; DIAGNOSTIC RADIOGRAPHY; GAMMA RADIOGRAPHY; MAGNETIC RESONANCE IMAGING; MICELLES;

AMPHIPHILIC BLOCK COPOLYMERS; DRUG CARRIERS; GAMMA SCINTIGRAPHY; POLYMERIC MICELLES;

BIOPOLYMERS;

AMPHOPHILE; COPOLYMER; DIAGNOSTIC AGENT; DRUG CARRIER; GADOLINIUM; GADOLINIUM PENTETATE; INDIUM 111; IODINE; MACROGOL; OCTADECYLAMINE; PENTETIC ACID; PHOSPHATIDYLETHANOLAMINE; POLYMER;

ANIMAL EXPERIMENT; BLOOD POOL SCINTISCANNING; COMPUTER ASSISTED TOMOGRAPHY; CONJUGATE; DIAGNOSTIC IMAGING; GAMMA SCINTIGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; LIVER; LYMPHOGRAPHY; MICELLE; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PARTICULATE MATTER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0344958777     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00100-8     Document Type: Review

References (35)

1. S.S. Illum, Davis, Effect of nonionic surfactant Poloxamer 338 on the fate and deposition of polystyrene microspheres following intravenous administration, J. Pharm. Sci. 72 (1983) 1086-1090.
2. Gref, Y. Minamitake, M.T. Peracchia, V.S. Trubetskoy, V.P. Torchilin, R. Langer, Biodegradable long-circulating nanospheres, Science 263 (1994) 1600-1603.
3. H. Bader, B. Ringsdorf, Schmid, Water-soluble polymers in medicine, Angew. Makromol. Chem. 123-124 (1984) 457-485.
4. C. Tilcock, Q.F. Ahkong, D. Fisher, Polymer-derivatized technetium-99m-labeled liposomal blood pool agents for nuclear medicine applications, Biochim. Biophys. Acta 1148 (1993) 77-84.
5. C. Tilcock, Q.F. Ahkong, D. Fisher, 99mTc-labeling of lipid vesicles containing the lipophilic chelator PE-DTTA: effect of tin-to-chelate ratio, chelate content and surface polymer on labeling efficiency and biodistribution behavior, Nucl. Med. Biol. 21 (1994) 89-96.
6. K. Kataoka, G.S. Kwon, M. Yokoyama, T. Okano, Y. Sakurai, Block copolymer micelles as vehicles for drug delivery, J. Control. Release 24 (1993) 119-132.
7. H.G. Enoch, P. Strittmatter, Formation and properties of 1000-A-diameter, single-bilayer phospholipid vesicles, Proc. Natl. Acad. Sci. USA 76 (1979) 145-149.
8. Z. Tuzar, P. Kratochvil, Micelles of block- and graft-copolymers in solutions, in: E. Matijevic (Ed.), Surface and Colloid Science, vol. 15, Plenum Press, New York, 1993, pp. 1-83.
9. L. Zhang, K. Yu, A. Bisenberg, Ion-induced morphological changes in crew-cut aggregates of amphiphilic block copolymers, Science 272 (1996) 1777-1779.
10. Z. Zhou, B. Chu, Light scattering study on the association behavior of triblock polymers of ethylene oxide and propylene oxide in aqueous solution, J. Colloid Interface Sci. 126 (1988) 171-180.
11. C.L. Zhao, M.A. Winnik, G. Riess, M.D. Croucher, Fluorescence probe techniques used to study micelle formation in water-soluble block copolymers, Langmuir 6 (1990) 514-516.
12. M. Wilhelm, C.L. Zhao, Y. Wang, R. Xu, M.A. Winnik, J.L. Mura, G. Riess, M.D. Croucher, Poly(styrene-ethyleneoxide) block copolymer micelle formation in water: a fluorescence probe study, Macromolecules 24 (1991) 1033-1040.
13. J.H. Collet, E.A. Tobin, Relationships between poloxamer structure and the solubilization of some para-substituted acetanilides, J. Pharm. Pharmacol. 31 (1979) 174-177.
14. S.-Y. Lin, Y. Kawashima, The influence of poly(oxyethylene) poly(oxypropylene) surface-active block copolymers on the solubility behavior of indomethacin, Pharm. Acta Helv. 60 (1985) 339-344.
15. A. Sparreboom, O. van Tellingen, W.J. Nooijen, J.H. Beijnen, Preclinical pharmacokinetics of paclitaxel and docetaxel, Anticancer Drugs 9 (1998) 1-17.
16. A. Haberland, W. Henke, T. Grune, W. Siems, K. Jung, I. Schimke, Differential response of oxygen radical metabolism in rat heart, liver and kidney to cyclosporine A treatment, Inflamm. Res. 46 (1997) 452-454.
17. G.S. Kwon, M. Naito, M. Yokoyama, T. Okano, Y. Sakurai, K. Kataoka, Physical entrapment of adriamycin in AB block copolymer micelles, Pharm. Res. 12 (1995) 192-195.
18. M. Yokoyama, Block copolymers as drug carriers, Crit. Rev. Ther. Drug Carrier Syst. 9 (1992) 213-248.
19. G.L. Wolf, Targeted delivery of imaging agents: an overview, in: V.P. Torchilin (Ed.), Targeted Delivery of Imaging Agents, CRC Press, Boca Raton, FL, 1995, pp. 3-22.
20. P.D. Stein, Diagnosis of pulmonary embolism, Curr. Opin. Pulm. Med. 2 (1996) 295-299.
21. G.D. Rubin, Helical CT angiography of the thoracic aorta, J. Thorac. Imaging 12 (1997) 128-149.
22. C. Tilcock, Q.F. Ahkong, S.H. Koenig, R.D. Brown III, M. Davis, G. Kabalka, The design of liposomal paramagnetic MR agents: effect of vesicle size upon the relaxivity of surface-incorporated lipophilic chelates, Magn. Res. Med. 27 (1992) 44-51.
23. V.S. Trubetskoy, V.P. Torchilin, New approaches in the chemical design of Gd-containing liposomes for use in magnetic resonance imaging of lymph nodes, J. Liposome Res. 4 (1994) 961-980.
24. D.J. Hnatowich, W.W. Layne, R.L. Childs, D. Lanteigne, M.A. Davis, T.W. Griffin, P.W. Doherty, Radioactive labeling of antibody: a simple and efficient method, Science 220 (1983) 613-615.
25. R.B. Lauffer, Mechanisms of magnetic resonance contrast enhancement by relaxivity and magnetic susceptibility agents, Invest. Radiol. 25 (1990) S32-S33.
26. C.W.M. Grant, S. Karlik, E.A. Flono, Liposomal MRI contrast agent: phosphatidyl ethanolamine, Magn. Res. Med. 11 (1989) 236-243.
27. G. Kabalka, E. Buonocore, K. Hubner, M. Davis, L. Huang, Gadolinium-labeled liposomes containing paramagnetic amphipathic agents: targeted MRI contrast agent for the liver, Magn. Res. Med. 8 (1988) 89-95.
28. E. Unger, D. Shen, T. Fritz, G.L. Wu, B. Kulik, T. New, T. Matsunaga, R. Ramaswami, Liposomes bearing membrane-bound complexes of manganese as magnetic resonance contrast agents, Invest. Radiol. 29 (1994) S168-S169.
29. P. Dawson, The non-ionic isotonic contrast agents. Perspectives and controversies, Eur. Radiol. 6 (1996) S20-S24.
30. L. Lauteala, M. Kormano, M.R. Violante, Uptake and dissolution of particulate iodipamide ethyl ester in the spleen, Invest. Radiol. 22 (1987) 829-835.
31. C. Li, D. Yu, Z. Kan, D.J. Yang, W. Tansey, L.R. Kuang, S. Wallace, Biodistribution of cyclic carbonate of ioxilan: a radiopaque particulate macrophage imaging a gent, Acad. Radiol. 3 (1996) 500-506.
32. D.D. Lasic, M.C. Woodle, F.J. Martin, T. Valentincic, Phase behavior of stealth-lipid-lecithin mixtures, Period. Biol. 93 (1991) 287-290.
33. V.S. Trubetskoy, M.D. Frank-Kamenetsky, V.P. Torchilin, Polyoxyethylene-lipid micelles loaded with solubilized amphiphilic compounds, Proc. Int. Symp. Control. Release Bioact. Mater. 23 (1996) 781-782.
34. V.S. Trubetskoy, M.D. Frank-Kamenetsky, K.R. Whitheman, V.P. Torchilin, Stable polymeric micelles: lymphangiographic contrast media for gamma scintigraphy and magnetic resonance imaging, Acad. Radiol. 3 (1996) 232-238.
35. V.S. Trubetskoy, G.S. Gazelle, G.L. Wolf, V.P. Torchilin, Block-copolymer of polyethylene glycol and polylysine as a carrier of organic iodine: design of long-circulating particulate contrast medium for X-ray computed tomography, J. Drug Targeting 4 (1997) 381-388.