메뉴 건너뛰기




Volumn 22, Issue 4, 2010, Pages 1111-1122

BACE1 mRNA expression in Alzheimer's disease postmortem brain tissue

Author keywords

Amyloid protein precursor; Braak staging; gene expression; Lewy body disease; Parkinson's disease; protease; qPCR; reference gene; reverse transcriptase polymerase chain reaction

Indexed keywords

BETA SECRETASE 1; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; NEURON SPECIFIC ENOLASE;

EID: 78650233443     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-101254     Document Type: Article
Times cited : (57)

References (40)
  • 5
    • 34250847115 scopus 로고    scopus 로고
    • The proteins BACE1 and BACE2 and β-secretase activity in normal and Alzheimer's disease brain
    • DOI 10.1042/BST0350574
    • Stockley JH, O'Neill C (2007) The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain. Biochem Soc Trans 35, 574-576. (Pubitemid 46975079)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.3 , pp. 574-576
    • Stockley, J.H.1    O'Neill, C.2
  • 6
    • 63949088562 scopus 로고    scopus 로고
    • Function, regulation and therapeutic properties of beta-secretase (BACE1)
    • Willem M, Lammich S, Haass C (2009) Function, regulation and therapeutic properties of beta-secretase (BACE1). Semin Cell Dev Biol 20, 175-182.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 175-182
    • Willem, M.1    Lammich, S.2    Haass, C.3
  • 7
    • 77953193048 scopus 로고    scopus 로고
    • Changes with Age in the Activities of beta-secretase and the Abeta-degrading Enzymes Neprilysin, Insulin-degrading Enzyme and Angiotensin-converting Enzyme
    • Miners JS, van Helmond Z, Kehoe PG, Love S (2010) Changes with Age in the Activities of beta-secretase and the Abeta-degrading Enzymes Neprilysin, Insulin-degrading Enzyme and Angiotensin-converting Enzyme. Brain Pathol 20, 794-802.
    • (2010) Brain Pathol , vol.20 , pp. 794-802
    • Miners, J.S.1    Van Helmond, Z.2    Kehoe, P.G.3    Love, S.4
  • 8
    • 34147120073 scopus 로고    scopus 로고
    • β-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: Implications for Alzheimer's disease pathogenesis
    • DOI 10.1523/JNEUROSCI.4396-06.2007
    • Zhao J, Fu Y, Yasvoina M, Shao P, Hitt B, O'Connor T, Logan S, Maus E, Citron M, Berry R, Binder L, Vassar R (2007) Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis. J Neurosci 27, 3639-3649. (Pubitemid 46557686)
    • (2007) Journal of Neuroscience , vol.27 , Issue.14 , pp. 3639-3649
    • Zhao, J.1    Fu, Y.2    Yasvoina, M.3    Shao, P.4    Hitt, B.5    O'Connor, T.6    Logan, S.7    Maus, E.8    Citron, M.9    Berry, R.10    Binder, L.11    Vassar, R.12
  • 9
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
    • DOI 10.1002/ana.10208
    • Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G (2002) Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 51, 783-786. (Pubitemid 34568861)
    • (2002) Annals of Neurology , vol.51 , Issue.6 , pp. 783-786
    • Holsinger, R.M.D.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 10
    • 0035900189 scopus 로고    scopus 로고
    • Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain
    • DOI 10.1016/S0006-8993(01)03008-6, PII S0006899301030086
    • Yasojima K, McGeer EG, McGeer PL (2001) Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain. Brain Res 919, 115-121. (Pubitemid 33016594)
    • (2001) Brain Research , vol.919 , Issue.1 , pp. 115-121
    • Yasojima, K.1    McGeer, E.G.2    McGeer, P.L.3
  • 14
    • 0036668567 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): Trends and problems
    • DOI 10.1677/jme.0.0290023
    • Bustin SA (2002) Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J Mol Endocrinol 29, 23-39. (Pubitemid 34965744)
    • (2002) Journal of Molecular Endocrinology , vol.29 , Issue.1 , pp. 23-39
    • Bustin, S.A.1
  • 15
    • 0033836029 scopus 로고    scopus 로고
    • Control selection for RNA quantitation
    • Suzuki T, Higgins PJ, Crawford DR (2000) Control selection for RNA quantitation. BioTechniques 29, 332-337. (Pubitemid 30658285)
    • (2000) BioTechniques , vol.29 , Issue.2 , pp. 332-337
    • Suzuki, T.1    Higgins, P.J.2    Crawford, D.R.3
  • 16
    • 21344471138 scopus 로고    scopus 로고
    • Real-time RT-PCR normalisation; strategies and considerations
    • DOI 10.1038/sj.gene.6364190
    • Huggett J, Dheda K, Bustin S, Zumla A (2005) Real-time RT-PCR normalisation; strategies and considerations. Genes Immun 6, 279-284. (Pubitemid 40903399)
    • (2005) Genes and Immunity , vol.6 , Issue.4 , pp. 279-284
    • Huggett, J.1    Dheda, K.2    Bustin, S.3    Zumla, A.4
  • 18
    • 0027490614 scopus 로고
    • Staging of Alzheimer-related cortical destruction
    • Braak H, Braak E, Bohl J (1993) Staging of Alzheimer-related cortical destruction. Eur Neurol 33, 403-408. (Pubitemid 23358066)
    • (1993) European Neurology , vol.33 , Issue.6 , pp. 403-408
    • Braak, H.1    Braak, E.2    Bohl, J.3
  • 19
    • 0026619925 scopus 로고
    • Brain banking and the human hypothalamus - Factors to match for, pitfalls and potentials
    • Ravid R, Van Zwieten EJ, Swaab DF (1992) Brain banking and the human hypothalamus - factors to match for, pitfalls and potentials. Prog Brain Res 93, 83-95. (Pubitemid 23008658)
    • (1992) Progress in Brain Research , vol.93 , pp. 83-95
    • Ravid, R.1    Van Zwieten, E.J.2    Swaab, D.F.3
  • 20
    • 43449119536 scopus 로고    scopus 로고
    • Standard Operating Procedures, ethical and legal regulations in BTB (Brain/Tissue/Bio) banking: What is still missing?
    • Ravid R (2008) Standard Operating Procedures, ethical and legal regulations in BTB (Brain/Tissue/Bio) banking: what is still missing? Cell Tissue Bank 9, 121-137.
    • (2008) Cell Tissue Bank , vol.9 , pp. 121-137
    • Ravid, R.1
  • 21
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944. (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 22
    • 0028845078 scopus 로고
    • The relative importance of premortem acidosis and postmortem interval for human braingene expression studies: Selective mRNA vulnerability and comparison with their encoded proteins
    • Harrison PJ, Heath PR, Eastwood SL, Burnet PW, McDonald B, Pearson RC (1995) The relative importance of premortem acidosis and postmortem interval for human braingene expression studies: selective mRNA vulnerability and comparison with their encoded proteins. Neurosci Lett 200, 151-154.
    • (1995) Neurosci Lett , vol.200 , pp. 151-154
    • Harrison, P.J.1    Heath, P.R.2    Eastwood, S.L.3    Burnet, P.W.4    McDonald, B.5    Pearson, R.C.6
  • 23
    • 0141957335 scopus 로고    scopus 로고
    • Quantifying mRNA in postmortem human brain: Influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance
    • DOI 10.1016/S0169-328X(03)00337-1
    • Preece P, Cairns NJ (2003) Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance. Brain Res Mol Brain Res 118, 60-71. (Pubitemid 37238988)
    • (2003) Molecular Brain Research , vol.118 , Issue.1-2 , pp. 60-71
    • Preece, P.1    Cairns, N.J.2
  • 26
    • 45449087921 scopus 로고    scopus 로고
    • QBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
    • Hellemans J, Mortier G, De Paepe A, Speleman F, Vandes-ompele J (2007) qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol 8, R19.
    • (2007) Genome Biol , vol.8
    • Hellemans, J.1    Mortier, G.2    De Paepe, A.3    Speleman, F.4    Vandes-Ompele, J.5
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 72949089907 scopus 로고    scopus 로고
    • Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloido-genesis: Implications for neuritic plaque development
    • Zhang XM, Cai Y, Xiong K, Cai H, Luo XG, Feng JC, Clough RW, Struble RG, Patrylo PR, Yan XX (2009) Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloido-genesis: implications for neuritic plaque development. Eur J Neurosci 30, 2271-2283.
    • (2009) Eur J Neurosci , vol.30 , pp. 2271-2283
    • Zhang, X.M.1    Cai, Y.2    Xiong, K.3    Cai, H.4    Luo, X.G.5    Feng, J.C.6    Clough, R.W.7    Struble, R.G.8    Patrylo, P.R.9    Yan, X.X.10
  • 29
    • 24644441051 scopus 로고    scopus 로고
    • Measuring morphological and cellular changes in Alzheimer's dementia: A review emphasizing stereology
    • DOI 10.2174/156720505774330528
    • Stark AK, Pelvig DP, Jorgensen AM, Andersen BB, Pakken-berg B (2005) Measuring morphological and cellular changes in Alzheimer's dementia: a review emphasizing stereology. Curr Alzheimer Res 2, 449-481. (Pubitemid 41277759)
    • (2005) Current Alzheimer Research , vol.2 , Issue.4 , pp. 449-481
    • Stark, A.K.1    Pelvig, D.P.2    Jorgensen, A.-M.B.3    Andersen, B.B.4    Pakkenberg, B.5
  • 30
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • DOI 10.1016/S0140-6736(94)92338-8
    • West MJ, Coleman PD, Flood DG, Troncoso JC (1994) Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344, 769-772. (Pubitemid 24283954)
    • (1994) Lancet , vol.344 , Issue.8925 , pp. 769-772
    • West, M.J.1    Coleman, P.D.2    Flood, D.G.3    Troncoso, J.C.4
  • 32
    • 0028271519 scopus 로고
    • Decreased neuronal activity in the nucleus basalis of Meynert in Alzheimer's disease as suggested by the size of the Golgi apparatus
    • DOI 10.1016/0306-4522(94)90291-7
    • SalehiA, Lucassen PJ, Pool CW, Gonatas NK, Ravid R, Swaab DF (1994) Decreased neuronal activity in the nucleus basalis of Meynert in Alzheimer's disease as suggested by the size of the Golgi apparatus. Neuroscience 59, 871-880. (Pubitemid 24149097)
    • (1994) Neuroscience , vol.59 , Issue.4 , pp. 871-880
    • Salehi, A.1    Lucassen, P.J.2    Pool, C.W.3    Gonatas, N.K.4    Ravid, R.5    Swaab, D.F.6
  • 33
    • 0019494341 scopus 로고
    • Some morphometric aspects of the brain in senile dementia of the Alzheimer type
    • DOI 10.1002/ana.410100209
    • Terry RD, Peck A, DeTeresa R, Schechter R, Horoupian DS (1981) Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 10, 184-192. (Pubitemid 11053105)
    • (1981) Annals of Neurology , vol.10 , Issue.2 , pp. 184-192
    • Terry, R.D.1    Peck, A.2    DeTeresa, R.3
  • 34
    • 77049085956 scopus 로고    scopus 로고
    • Astro-cyte phenotype in relation to Alzheimer-type pathology in the ageing brain
    • MRC Cognitive Function and Ageing Neuropathology Study Group
    • Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB, MRC Cognitive Function and Ageing Neuropathology Study Group (2010) Astro-cyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiol Aging 31, 578-590.
    • (2010) Neurobiol Aging , vol.31 , pp. 578-590
    • Simpson, J.E.1    Ince, P.G.2    Lace, G.3    Forster, G.4    Shaw, P.J.5    Matthews, F.6    Savva, G.7    Brayne, C.8    Wharton, S.B.9
  • 35
    • 13244264935 scopus 로고    scopus 로고
    • Alzheimer's disease β-secretase BACE1 is not a neuron-specific enzyme
    • DOI 10.1111/j.1471-4159.2004.02857.x
    • Rossner S, Lange-Dohna C, Zeitschel U, Perez-Polo JR (2005) Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme. J Neurochem 92, 226-234. (Pubitemid 40194014)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.2 , pp. 226-234
    • Rossner, S.1    Lange-Dohna, C.2    Zeitschel, U.3    Perez-Polo, J.R.4
  • 37
    • 74049090496 scopus 로고    scopus 로고
    • Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain
    • Ye JT, Pi RB, Mao XX, Chen XH, Qin J, Xu SW, Liu PQ (2009) Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain. Neuroreport 20, 1456-1460.
    • (2009) Neuroreport , vol.20 , pp. 1456-1460
    • Ye, J.T.1    Pi, R.B.2    Mao, X.X.3    Chen, X.H.4    Qin, J.5    Xu, S.W.6    Liu, P.Q.7
  • 39
    • 27544475345 scopus 로고    scopus 로고
    • Is there a role of the cyclin-dependent kinase 5 activator p25 in Alzheimer's disease?
    • DOI 10.1097/01.wnr.0000185019.67434.d2
    • Giese KP, Ris L, Plattner F (2005) Is there a role of the cyclin-dependent kinase 5 activator p25in Alzheimer's disease? Neu-roreport 16, 1725-1730. (Pubitemid 41547036)
    • (2005) NeuroReport , vol.16 , Issue.16 , pp. 1725-1730
    • Giese, K.P.1    Ris, L.2    Plattner, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.