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Volumn 91, Issue 2, 2011, Pages 218-225

Protective effect of dried safflower petal aqueous extract and its main constituent, carthamus yellow, against lipopolysaccharide-induced inflammation in RAW264.7 macrophages

Author keywords

Carthamus tinctorius L.; Carthamus yellow; Cyclooxygenase 2; Inducible nitric oxide synthase; Lipopolysaccharide; Safflower

Indexed keywords

AUTACOID; CARTHAMUS YELLOW; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHENOL DERIVATIVE; PLANT EXTRACT;

EID: 78650207634     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.4172     Document Type: Article
Times cited : (64)

References (50)
  • 1
    • 4644359359 scopus 로고    scopus 로고
    • Regulation of the expression of inducible nitric oxide synthase
    • Kleinert H, Pautz A, Linker K Schwarz PM, Regulation of the expression of inducible nitric oxide synthase. Eur J Pharmacol 500: 255-266 (2004).
    • (2004) Eur J Pharmacol , vol.500 , pp. 255-266
    • Kleinert, H.1    Pautz, A.2    Linker, K.3    Schwarz, P.M.4
  • 2
    • 0036229078 scopus 로고    scopus 로고
    • Role of nitric oxide in inflammatory conditions
    • Blantz RC Munger K, Role of nitric oxide in inflammatory conditions. Nephron 90: 3773-3378 (2002).
    • (2002) Nephron , vol.90 , pp. 3773-3378
    • Blantz, R.C.1    Munger, K.2
  • 4
    • 33750840014 scopus 로고    scopus 로고
    • Macrophage activation: role of toll-like receptors, nitric oxide, and nuclear factor kappa B
    • Billack B, Macrophage activation: role of toll-like receptors, nitric oxide, and nuclear factor kappa B. Am J Pharm Educ 70: 102 (2006).
    • (2006) Am J Pharm Educ , vol.70 , pp. 102
    • Billack, B.1
  • 5
    • 0035793684 scopus 로고    scopus 로고
    • NF-κB activation and IκB: a dynamism involved in iNOS and chemokine induction in astroglial cells
    • Nomura Y, NF-κB activation and IκB: a dynamism involved in iNOS and chemokine induction in astroglial cells. Life Sci 68: 1695-1701 (2001).
    • (2001) Life Sci , vol.68 , pp. 1695-1701
    • Nomura, Y.1
  • 6
    • 7044262053 scopus 로고
    • Evolution of Crop Plants
    • in (2nd edn), ed. by Smartt J, Simmonds NW. Longman, Harlow, UK
    • Knowles PF Ashri A, Safflower: Carthamus tinctorius (Compositae), in Evolution of Crop Plants (2nd edn), ed. by Smartt J, Simmonds NW. Longman, Harlow, UK, pp. 47-50 (1995).
    • (1995) Safflower: Carthamus tinctorius (Compositae) , pp. 47-50
    • Knowles, P.F.1    Ashri, A.2
  • 7
    • 59649124165 scopus 로고
    • Clinical application of safflower (Carthamus tinctorius)
    • Wang G Li Y, Clinical application of safflower (Carthamus tinctorius). Zhejiang Trad Chin Med Sci J 20: 42-43 (1985).
    • (1985) Zhejiang Trad Chin Med Sci J , vol.20 , pp. 42-43
    • Wang, G.1    Li, Y.2
  • 8
    • 78650206313 scopus 로고
    • Effects of some herbs on microcirculation of blood of rat's mesentery
    • Qi M, Li C, Lu H Liu W, Effects of some herbs on microcirculation of blood of rat's mesentery. J Chin Trad Med 25: 65-67 (1984).
    • (1984) J Chin Trad Med , vol.25 , pp. 65-67
    • Qi, M.1    Li, C.2    Lu, H.3    Liu, W.4
  • 9
    • 0027034779 scopus 로고
    • Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma rennin activity and angiotensin II level
    • Liu F, Yang XZ, Li FG, Hu J Cheng RF, Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma rennin activity and angiotensin II level. Acta Pharm Suec 27: 785-787 (1992).
    • (1992) Acta Pharm Suec , vol.27 , pp. 785-787
    • Liu, F.1    Yang, X.Z.2    Li, F.G.3    Hu, J.4    Cheng, R.F.5
  • 10
    • 84992448933 scopus 로고
    • Studies on pharmacology of safflower and saffron crocus
    • Sun S, Studies on pharmacology of safflower and saffron crocus. J Chin Med Sci 5: 443-448 (1995).
    • (1995) J Chin Med Sci , vol.5 , pp. 443-448
    • Sun, S.1
  • 11
    • 78650200263 scopus 로고
    • Effects of safflower yellow pigment on the blood fat and liver function of rabbits
    • Qi W, Zheng Y, Wei D, Zhang Y Yang J, Effects of safflower yellow pigment on the blood fat and liver function of rabbits. J Lanzh Coll Med Sci 3: 57-60 (1987).
    • (1987) J Lanzh Coll Med Sci , vol.3 , pp. 57-60
    • Qi, W.1    Zheng, Y.2    Wei, D.3    Zhang, Y.4    Yang, J.5
  • 12
    • 78650196938 scopus 로고
    • Effects of safflower on blood coagulation function of big rat
    • Li C, Yan S, Zhao F Yan D, Effects of safflower on blood coagulation function of big rat. Trad Chin Med 14: 27-28 (1983).
    • (1983) Trad Chin Med , vol.14 , pp. 27-28
    • Li, C.1    Yan, S.2    Zhao, F.3    Yan, D.4
  • 13
    • 39149131033 scopus 로고    scopus 로고
    • Selection of component drug in activating blood flow and removing blood stasis of Chinese herbal medicinal formula for dairy cow mastitis by hemorheological method
    • Lu Y, Hu YL, Kong XF Wang DY, Selection of component drug in activating blood flow and removing blood stasis of Chinese herbal medicinal formula for dairy cow mastitis by hemorheological method. J Ethnopharmacol 116: 313-317 (2008).
    • (2008) J Ethnopharmacol , vol.116 , pp. 313-317
    • Lu, Y.1    Hu, Y.L.2    Kong, X.F.3    Wang, D.Y.4
  • 14
    • 77957702225 scopus 로고
    • An analysis on the clinical treatment of male sterility of 300 cases by kidney-benefited and invigorating blood-circulation decoction
    • Qin Y, An analysis on the clinical treatment of male sterility of 300 cases by kidney-benefited and invigorating blood-circulation decoction. Jiangxi Trad Chin Med 21: 21-22 (1990).
    • (1990) Jiangxi Trad Chin Med , vol.21 , pp. 21-22
    • Qin, Y.1
  • 15
    • 77957693095 scopus 로고
    • Clinical observation on dead sperm excess disease of 182 cases
    • Qu C, Clinical observation on dead sperm excess disease of 182 cases. Shanghai Trad Chin Med J 5: 28-29 (1990).
    • (1990) Shanghai Trad Chin Med J , vol.5 , pp. 28-29
    • Qu, C.1
  • 16
    • 78650209466 scopus 로고    scopus 로고
    • The treatment of thorax rheumatism of 800 cases with milkvetch-peach-safflower, etc. decoction
    • Zheng Y, The treatment of thorax rheumatism of 800 cases with milkvetch-peach-safflower, etc. decoction. Liaoning Trad Chin Med Sci J 12: 19-20 (1998).
    • (1998) Liaoning Trad Chin Med Sci J , vol.12 , pp. 19-20
    • Zheng, Y.1
  • 17
    • 45749149638 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action
    • Tian J, Li G, Liu Z Fu F, Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action. Pharmacology 82: 121-126 (2008).
    • (2008) Pharmacology , vol.82 , pp. 121-126
    • Tian, J.1    Li, G.2    Liu, Z.3    Fu, F.4
  • 18
    • 58849091706 scopus 로고    scopus 로고
    • Effect of hydroxysafflor yellow A on human umbilical vein endothelial cells under hypoxia
    • Ji DB, Zhang LY, Li CL, Ye J Zhu HB, Effect of hydroxysafflor yellow A on human umbilical vein endothelial cells under hypoxia. Pharmacology 50: 137-145 (2009).
    • (2009) Pharmacology , vol.50 , pp. 137-145
    • Ji, D.B.1    Zhang, L.Y.2    Li, C.L.3    Ye, J.4    Zhu, H.B.5
  • 19
    • 56149108015 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax
    • Ji DB, Zhu MC, Zhu B, Zhu YZ, Li CL, Ye J, et al, Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax. J Cardiovasc Pharmacol 52: 191-202 (2008).
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 191-202
    • Ji, D.B.1    Zhu, M.C.2    Zhu, B.3    Zhu, Y.Z.4    Li, C.L.5    Ye, J.6
  • 20
    • 37349053781 scopus 로고    scopus 로고
    • Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis Draconis, a dragon's blood resin, in RAW 264.7 cells
    • Choy CS, Hu CM, Chiu WT, Lam CSK, Ting Y, Tsai SH, et al, Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis Draconis, a dragon's blood resin, in RAW 264.7 cells. J Ethnopharmacol 115: 455-462 (2008).
    • (2008) J Ethnopharmacol , vol.115 , pp. 455-462
    • Choy, C.S.1    Hu, C.M.2    Chiu, W.T.3    Lam, C.S.K.4    Ting, Y.5    Tsai, S.H.6
  • 21
    • 0032041067 scopus 로고    scopus 로고
    • Triclosan: cytotoxicity, mode of action, and induction of apoptosis in human gingival cells in vitro
    • Zuckerbraun HL, Babich H, May R Sinensky MC, Triclosan: cytotoxicity, mode of action, and induction of apoptosis in human gingival cells in vitro. Eur J Oral Sci 106: 628-636 (1998).
    • (1998) Eur J Oral Sci , vol.106 , pp. 628-636
    • Zuckerbraun, H.L.1    Babich, H.2    May, R.3    Sinensky, M.C.4
  • 22
    • 58049109655 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide
    • Hu CM, Liu YH, Cheah KP, Li JS, Lam CSK, Yu WY, et al, Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide. J Ethnopharmacol 121: 79-85 (2009).
    • (2009) J Ethnopharmacol , vol.121 , pp. 79-85
    • Hu, C.M.1    Liu, Y.H.2    Cheah, K.P.3    Li, J.S.4    Lam, C.S.K.5    Yu, W.Y.6
  • 23
    • 0020047061 scopus 로고
    • Mutagenicity screening of crude drugs with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay
    • Morimoto I, Watanabe F Osawa T, Okitsu T Kada T, Mutagenicity screening of crude drugs with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay. Mutat Res 97: 81-102 (1982).
    • (1982) Mutat Res , vol.97 , pp. 81-102
    • Morimoto, I.1    Watanabe, F.2    Osawa, T.3    Okitsu, T.4    Kada, T.5
  • 24
    • 0025757070 scopus 로고
    • A study on the mutagenicity of 102 raw pharmaceuticals used in Chinese traditional medicine
    • Yin XJ, Liu D, Wang H Zhou Y, A study on the mutagenicity of 102 raw pharmaceuticals used in Chinese traditional medicine. Mutat Res 260: 73-82 (1991).
    • (1991) Mutat Res , vol.260 , pp. 73-82
    • Yin, X.J.1    Liu, D.2    Wang, H.3    Zhou, Y.4
  • 27
  • 29
    • 26444535295 scopus 로고    scopus 로고
    • The kinase inhibitor imatinib mesylate inhibits TNF-α production in vitro and prevents TNF-dependent acute hepatic inflammation
    • Wolf AM, Wolf D, Rumpold H, Ludwiczek S, Enrich B, Gastl G, et al, The kinase inhibitor imatinib mesylate inhibits TNF-α production in vitro and prevents TNF-dependent acute hepatic inflammation. Proc Natl Acad Sci USA 20: 13622-13627 (2005).
    • (2005) Proc Natl Acad Sci USA , vol.20 , pp. 13622-13627
    • Wolf, A.M.1    Wolf, D.2    Rumpold, H.3    Ludwiczek, S.4    Enrich, B.5    Gastl, G.6
  • 30
    • 0034450123 scopus 로고    scopus 로고
    • Molecular mechanisms of NF-κB activation induced by bacterial lipopolysaccharide through Toll-like receptors
    • Zhang G Ghosh S, Molecular mechanisms of NF-κB activation induced by bacterial lipopolysaccharide through Toll-like receptors. J Endotoxin Res 6: 453-457 (2000).
    • (2000) J Endotoxin Res , vol.6 , pp. 453-457
    • Zhang, G.1    Ghosh, S.2
  • 31
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh S Karin M, Missing pieces in the NF-κB puzzle. Cell 109: 81-96 (2002).
    • (2002) Cell , vol.109 , pp. 81-96
    • Ghosh, S.1    Karin, M.2
  • 32
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: new discoveries and insights
    • Baldwin ASJ, The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol 14: 649-683 (1996).
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, A.S.J.1
  • 33
    • 0032217267 scopus 로고    scopus 로고
    • IκB-NF-κB structures: at the interface of inflammation control
    • Baeuerle PA, IκB-NF-κB structures: at the interface of inflammation control. Cell 95: 729-731 (1998).
    • (1998) Cell , vol.95 , pp. 729-731
    • Baeuerle, P.A.1
  • 34
    • 33646270305 scopus 로고
    • An Illustrated Pharmacognosy
    • SMC Publishing, Taipei
    • Yen KY, An Illustrated Pharmacognosy. SMC Publishing, Taipei, p. 78 (1992).
    • (1992) , pp. 78
    • Yen, K.Y.1
  • 35
    • 62349128877 scopus 로고    scopus 로고
    • Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne)
    • Hiramatsu M, Takahashi T, Komatsu M, Kido T Kasahara Y, Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne). Neurochem Res 34: 795-805 (2009).
    • (2009) Neurochem Res , vol.34 , pp. 795-805
    • Hiramatsu, M.1    Takahashi, T.2    Komatsu, M.3    Kido, T.4    Kasahara, Y.5
  • 36
    • 51849102480 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats
    • Ye SY Gao WY, Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats. Arch Pharm Res 31: 1010-1015 (2008).
    • (2008) Arch Pharm Res , vol.31 , pp. 1010-1015
    • Ye, S.Y.1    Gao, W.Y.2
  • 37
    • 49049095526 scopus 로고    scopus 로고
    • Inhibitory action of hydroxysafflor yellow A on inflammatory signal transduction pathway related factors in rats with cerebral cortex ischemia
    • Chen TT, Du YJ, Liu XL Zhu HB, Inhibitory action of hydroxysafflor yellow A on inflammatory signal transduction pathway related factors in rats with cerebral cortex ischemia. Yao Xue Xue Bao 43: 570-575 (2008).
    • (2008) Yao Xue Xue Bao , vol.43 , pp. 570-575
    • Chen, T.T.1    Du, Y.J.2    Liu, X.L.3    Zhu, H.B.4
  • 38
    • 21344450534 scopus 로고    scopus 로고
    • Therapeutic effects of hydroxysafflor yellow A on focal cerebral ischemic injury in rats and its primary mechanisms
    • Zhu HB, Zhang L, Wang ZH, Tian JW, Fu FH, Liu K, et al, Therapeutic effects of hydroxysafflor yellow A on focal cerebral ischemic injury in rats and its primary mechanisms. J Asian Nat Prod Res 7: 607-613 (2005).
    • (2005) J Asian Nat Prod Res , vol.7 , pp. 607-613
    • Zhu, H.B.1    Zhang, L.2    Wang, Z.H.3    Tian, J.W.4    Fu, F.H.5    Liu, K.6
  • 39
    • 31644434141 scopus 로고    scopus 로고
    • Protective effect of hydroxysafflor yellow A on experimental cerebral ischemia in rats
    • Zhu HB, Wang ZH, Tian JW, Fu FH, Liu K Li CL, Protective effect of hydroxysafflor yellow A on experimental cerebral ischemia in rats. Yao Xue Xue Bao 40: 1144-1146 (2005).
    • (2005) Yao Xue Xue Bao , vol.40 , pp. 1144-1146
    • Zhu, H.B.1    Wang, Z.H.2    Tian, J.W.3    Fu, F.H.4    Liu, K.5    Li, C.L.6
  • 40
    • 22544451583 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action
    • Wei X, Liu H, Sun X, Fu F, Zhang X, Wang J, et al, Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action. Neurosci Lett 386: 58-62 (2005).
    • (2005) Neurosci Lett , vol.386 , pp. 58-62
    • Wei, X.1    Liu, H.2    Sun, X.3    Fu, F.4    Zhang, X.5    Wang, J.6
  • 41
    • 0038095439 scopus 로고    scopus 로고
    • Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies
    • Zhu H, Wang Z, Ma C, Tian J, Fu F, Li C, et al, Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. Planta Med 69: 429-433 (2003).
    • (2003) Planta Med , vol.69 , pp. 429-433
    • Zhu, H.1    Wang, Z.2    Ma, C.3    Tian, J.4    Fu, F.5    Li, C.6
  • 42
    • 33847408504 scopus 로고    scopus 로고
    • Neuroprotective effects of safflor yellow B on brain ischemic injury
    • Wang C, Zhang D, Li G, Liu J, Tian J, Fu F, et al, Neuroprotective effects of safflor yellow B on brain ischemic injury. Exp Brain Res 177: 533-539 (2007).
    • (2007) Exp Brain Res , vol.177 , pp. 533-539
    • Wang, C.1    Zhang, D.2    Li, G.3    Liu, J.4    Tian, J.5    Fu, F.6
  • 43
    • 0034211285 scopus 로고    scopus 로고
    • Influence of safflower injection on hemorheology of patients of chronic cor pulmonale during acute attack
    • Jin Y, Xu D Xu W, Influence of safflower injection on hemorheology of patients of chronic cor pulmonale during acute attack. Zhongguo Zhong Xi Yi Jie He Za Zhi 20: 430-432 (2000).
    • (2000) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.20 , pp. 430-432
    • Jin, Y.1    Xu, D.2    Xu, W.3
  • 44
    • 38049002019 scopus 로고    scopus 로고
    • Changes of ICAM-1 and P-selectin in rats with pulmonary thromboembolism and the effect of safflower injection
    • Zhang JC, Xia L Bai M, Changes of ICAM-1 and P-selectin in rats with pulmonary thromboembolism and the effect of safflower injection. Zhongguo Zhong Xi Yi Jie He Za Zhi 26: 629-632 (2006).
    • (2006) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.26 , pp. 629-632
    • Zhang, J.C.1    Xia, L.2    Bai, M.3
  • 45
    • 69849091816 scopus 로고    scopus 로고
    • Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes on human aortic endothelial cells
    • Piga R, Naito Y, Kokura S, Handa O Yoshikawa T, Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes on human aortic endothelial cells. Br J Nutr 102: 264-272 (2009).
    • (2009) Br J Nutr , vol.102 , pp. 264-272
    • Piga, R.1    Naito, Y.2    Kokura, S.3    Handa, O.4    Yoshikawa, T.5
  • 46
    • 0025953609 scopus 로고
    • Suppressive effects of safflower yellow on immune functions
    • Lu ZW, Liu F, Hu J, Bian D Li FG, Suppressive effects of safflower yellow on immune functions. Zhongguo Yao Li Xue Bao 12: 537-542 (1991).
    • (1991) Zhongguo Yao Li Xue Bao , vol.12 , pp. 537-542
    • Lu, Z.W.1    Liu, F.2    Hu, J.3    Bian, D.4    Li, F.G.5
  • 47
    • 0031425441 scopus 로고    scopus 로고
    • Immunomodulating activities of polysaccharide fractions from dried safflower petals
    • Wakabayashi T, Hirokawa S, Yamauhi N, Kataoka T, Woo J-T Nagai K, Immunomodulating activities of polysaccharide fractions from dried safflower petals. Cytotechnology 25: 205-211 (1997).
    • (1997) Cytotechnology , vol.25 , pp. 205-211
    • Wakabayashi, T.1    Hirokawa, S.2    Yamauhi, N.3    Kataoka, T.4    Woo, J.5    Nagai, K.6
  • 48
    • 0035993218 scopus 로고    scopus 로고
    • Safflower polysaccharides activate the transcription factor NF-κB via Toll-like receptor 4 and induce cytokine production by macrophages
    • Ando I, Tsukumo Y, Wakabayashi T, Akashi S, Miyake K, Kataoka T, et al, Safflower polysaccharides activate the transcription factor NF-κB via Toll-like receptor 4 and induce cytokine production by macrophages. Int Immunopharmacol 2: 1155-1162 (2002).
    • (2002) Int Immunopharmacol , vol.2 , pp. 1155-1162
    • Ando, I.1    Tsukumo, Y.2    Wakabayashi, T.3    Akashi, S.4    Miyake, K.5    Kataoka, T.6
  • 49
    • 60349116264 scopus 로고    scopus 로고
    • Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector
    • Fan L, Zhao HY, Xu M, Zhou L, Guo H, Han J, et al, Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector. J Chromatogr A 1216: 2063-2070 (2009).
    • (2009) J Chromatogr A , vol.1216 , pp. 2063-2070
    • Fan, L.1    Zhao, H.Y.2    Xu, M.3    Zhou, L.4    Guo, H.5    Han, J.6
  • 50
    • 33746504920 scopus 로고    scopus 로고
    • Serotonin derivatives, major safflower (Carthamus tinctorius L.) seed antioxidants, inhibit low-density lipoprotein (LDL) oxidation and atherosclerosis in apolipoprotein E-deficient mice
    • Koyama N, Kuribayashi K, Seki T, Kobayashi K, Furuhata Y, Suzuki K, et al, Serotonin derivatives, major safflower (Carthamus tinctorius L.) seed antioxidants, inhibit low-density lipoprotein (LDL) oxidation and atherosclerosis in apolipoprotein E-deficient mice. J Agric Food Chem 54: 4970-4976 (2006).
    • (2006) J Agric Food Chem , vol.54 , pp. 4970-4976
    • Koyama, N.1    Kuribayashi, K.2    Seki, T.3    Kobayashi, K.4    Furuhata, Y.5    Suzuki, K.6


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