Antioxidant and neuroprotective activities of mogami-benibana (safflower, carthamus tinctorius linne)

Neurochemical Research

Volumn 34, Issue 4, 2009, Pages 795-805

  Hiramatsu, Midori ^a   Takahashi, Tomoko ^a   Komatsu, Makiko ^b   Kido, Toshitaka ^c   Kasahara, Yoshimasa ^d  

^a Tohoku University of Community Services and Science   (Japan)

^b Yamagata Technopolis Foundation   (Japan)

^c TSUMURA AND CO   (Japan)

^d YAMAGATA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Brain oxidative damage; Carthamin; Free radical; Mice; Mogami benibana (safflower, Carthamus tinctorius Linne); Petals; Polyphenol; Rats

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 8 HYDROXYDEOXYGUANOSINE; CARTHAMIN; HYDROXYL RADICAL; MALONALDEHYDE; POLYPHENOL DERIVATIVE; SAFFLOWER EXTRACT; SCAVENGER; SINGLET OXYGEN; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; GLIA CELL; LIPID PEROXIDATION; MALE; MOTOR CORTEX; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PETAL; PLANT LEAF; PLANT ROOT; PLANT SEED; PLANT STEM; PRIORITY JOURNAL; RAT; SENSORY CORTEX;

ANIMALS; ANTIOXIDANTS; BRAIN; CARTHAMUS TINCTORIUS; CELL DEATH; CELL LINE; CHALCONE; DEOXYGUANOSINE; FREE RADICAL SCAVENGERS; FREE RADICALS; GLUCOSIDES; LIPID PEROXIDATION; MALE; MICE; NEUROGLIA; NEUROPROTECTIVE AGENTS; PLANT COMPONENTS; PLANT EXTRACTS; PLANT PREPARATIONS; RATS; RATS, WISTAR; SINGLET OXYGEN;

ANIMALIA; CARTHAMUS TINCTORIUS; MUS; RATTUS;

EID: 62349128877     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9884-5     Document Type: Article

References (21)

1. M Hiramatsu 2006
2. Packer L, Hiramatsu M, Yoshikawa T (eds) (1996) Free radicals in brain physiology and disorders. Academic Press, London
3. K Todoki E Okabe H Ogawa 1983 The increase in peripheral blood flow induced by Carthamus t. and Arnica m. Kanagawa Shigaku 18 64 69 (in Japansese)
4. K Ogata T Kimura E Hosoya T Sato 1990 Mutagenicity and antibacterial activity of Carthamus tinctorius L. I Yamagata Eiken-Shoho 23 43 48
5. H Kutsuna S Fujii K Kitamura 1988 Identification and determination of platelet aggregation inhibitor from safflower (Carthamus tinctorius Linne) Yakugaku Zasshi 108 1101 1103
6. X Huang M Hattori T Namba 1992 Effects of a carthami flos extract and its constituents on the beating amplitude of cultured myocardial cells sheets Shoyakugaku Zasshi 46 210 216
7. Y Kasahara 1988 Studies on physiologically active, natural products in Yamagata prefecture-pharamacological actions of Carthamus tinctrius Yamagata Eiken-Shoho 21 9 15
8. Y Kasahara 1991 Pharmacological studies on flower petals of Carthamus tinctrius (II) antiinflammatory effect Shoyakugaku Zasshi 45 306 315
9. Y Kasahara K Kumaki S Katagiri 1994 Carthamin flos extract and its component, stigmasterol, inhibit tumour promotion in mouse skin two-stage carcinogenesis Phyther Res 8 327 331 10.1002/ptr.2650080603
10. K Yasukawa T Akihisa T Kasahara 1996 Inhibitory effect of alkane-6, 8-diols, the components of safflower, on tumor promotion by 12-o- tetradecanoylphorbol -13-acetate in two-stage carcinogenesis in mouse skin Oncology 53 133 136
11. I Ando Y Tsukumo T Wakabayashi 2002 Safflower polysaccharides activate the transcription factor NF-kappa B via toll-like receptor 4 and induce cytokine production by macrophages Int Immunopharmacol 2 1155 1162 10.1016/S1567- 5769(02)00076-0
12. T Wakabayashi S Hirokawa N Yamauchi 1997 Immunomodulating activities of polysaccharide fractions from dried safflower petals Cytotechnology 25 205 211 10.1023/A:1007947329496
13. H Obara J Onodera S Sato 1993 Carthamin, the red pigment of safflower Bull Yamagata Univ 22 91 104
14. MVR Kumari T Yoneda M Hiramatsu 1996 Scavenging activity of "βcatechin" on reactive oxygen species generated by photosensitization of riboflavin Biochem Mol Biol Int 38 1163 1170
15. LJ Willmore GW Sypert JB Munson 1978 Chronic focal epileptiform discharges induced by injections of iron into rat and cat cortex Science 200 1501 1503 10.1126/science.96527
16. H Ohkawa N Onishi K Yagi 1979 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 351 358 10.1016/0003-2697(79) 90738-3
17. M Hiramatsu M Komatsu K Imao 2001
18. S Landau S Friedman S Brenner 2004 The value of safflower (Carthamus tinctorius) hay and silage grown under mediterranean conditions as forage for dairy cattle Livest Prod Sci 88 263 271 10.1016/j.livprodsci.2003.11.011
19. S Landau G Molle N Fois 2005 Safflower (Carthamus tinctorius L.) as a novel pasture species for dairy sheep in the mediterranean conditions of Sardiian and Israel Small Rumin Res 59 239 249 10.1016/j.smallrumres.2005.05.008
20. N Koyama K Kuribayashi T Seki 2006 Serotonin derivatives, major safflower (Carthamus tinctorius L.) seed antioxidants, inhibit low-density lipoprotein (LDL) oxidation and atherosclerosis in apolipoprotein E-deficient mice J Agric Food Chem 12 4970 4976 10.1021/jf060254p
21. DW Choi 1988 Glutamate neurotoxicity and disease of the nervous system Neuron 1 623 634 10.1016/0896-6273(88)90162-6