New synthesis of tic-hydantoins sigma-1 ligands and pharmacological evaluation on cocaine-induced stimulant effects

Medicinal Chemistry

Volumn 6, Issue 6, 2010, Pages 355-373

  Toussaint, M ^a,b   Debreu Fontaine, M A ^a,b   Maurice, T ^c,d,e   Melnyk, P ^a,b,f  

^a INSTITUT DE BIOLOGIE DE LILLE   (France)

^b UNIV LILLE   (France)

^c University of Montpellier   (France)

^d UNIV MONTPELLIER   (France)

^e PSL RESEARCH UNIVERSITY   (France)

^f EA 4481GRIIOT   (France)

Author keywords

1 protein; Addiction.; Agonist; Cocaine; Hydantoin; Isoquinoline

Indexed keywords

10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 10,10A DIHYDRO 5H OXAZOLO[3,4 B]ISOQUINOLINE 1,3 DIONE; 2 (2 [1,3]DIOXOLAN 2 YL ETHYL) 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 (3 AMINOPROPYL) 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 (3 DIETHYLAMINOPROPYL) 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 (3 DIISOBUTYLAMINOPROPYL) 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 (3 DIMETHYLAMINOPROPYL) 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 (4 NITROBENZYLAMINO)PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 (4 TERT BUTYLBENZYLAMINO)PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 [(4 FLUOROBENZYL)METHYLAMINO]PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 [(4 METHOXYBENZYL)METHYLAMINO]PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 [(4 TERT BUTYLBENZYL)METHYLAMINO]PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 [BIS(4 FLUOROBENZYL)AMINO]PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 2 [3 [METHYL(4 METHYLBENZYL)AMINO]PROPYL] 10,10A DIHYDRO 5H IMIDAZO[1,5 B]ISOQUINOLINE 1,3 DIONE; 3 (1,3 DIOXO 1,5,10,10A TETRAHYDROIMIDAZO[1,5 B]ISOQUINOLINE 2 YL) PROPIONALDEHYDE; CHAPERONE; COCAINE; DRUGS USED IN THE TREATMENT OF ADDICTION; HYDANTOIN; HYDANTOIN DERIVATIVE; IMIDAZOLE DERIVATIVE; ISOQUINOLINE; TERT BUTYL N {3 [(1,2,3,4 TETRAHYDROISOQUINOLINE 3 CARBOMOYL)AMINO]PROPYL}CARBAMATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; DRUG TARGETING; HYPERACTIVITY; IN VITRO STUDY; LOCOMOTION; PRIORITY JOURNAL;

CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; HUMANS; HYDANTOINS; LIGANDS; MOTOR ACTIVITY; RECEPTORS, SIGMA;

EID: 78650204000     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340610793563956     Document Type: Article

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