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Volumn 39, Issue 40, 1998, Pages 7373-7376

Rational design and synthesis of unsaturated 2,5-dioxopiperazine derivatives as potential protein tyrosine kinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

PIPERAZINE DERIVATIVE; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 0032190784     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01599-8     Document Type: Article
Times cited : (36)

References (18)
  • 6
    • 85038548961 scopus 로고    scopus 로고
    • note
    • 6. Energy minimizations were accomplished according to MacroModel v3.1X Program using MM2 force field. The superimposition RMS (overlap deviation) is 0.021 Å, which showed an obviously good fit.
  • 15
    • 85038543098 scopus 로고    scopus 로고
    • note
    • 15. Chiral HPLC analysis of the 2,5-dioxopiperazines from solution and solid phase method indicated only slight racemization. HPLC analytical separation achieved using a CHIRALCEL OJ column, eluting with ethanol at 1 ml/min.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.