-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Initial sequencing and analysis of the human genome. Nature. 2001;409: 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Han-nenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Francesco VD, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji R-R, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang ZY, Wang A, Wang X, Wang J, Wei M-H, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu SC, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers Y-H, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigo R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang Y-H, Coyne M, Dahlke C, Mays AD, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X. The sequence of the human genome. Science. 2001;291:1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
Broder, S.26
Clark, A.G.27
Nadeau, J.28
McKusick, V.A.29
Zinder, N.30
Levine, A.J.31
Roberts, R.J.32
Simon, M.33
Slayman, C.34
Hunkapiller, M.35
Bolanos, R.36
Delcher, A.37
Dew, I.38
Fasulo, D.39
Flanigan, M.40
Florea, L.41
Halpern, A.42
Han-Nenhalli, S.43
Kravitz, S.44
Levy, S.45
Mobarry, C.46
Reinert, K.47
Remington, K.48
Abu-Threideh, J.49
Beasley, E.50
Biddick, K.51
Bonazzi, V.52
Brandon, R.53
Cargill, M.54
Chandramouliswaran, I.55
Charlab, R.56
Chaturvedi, K.57
Deng, Z.58
Francesco, V.D.59
Dunn, P.60
Eilbeck, K.61
Evangelista, C.62
Gabrielian, A.E.63
Gan, W.64
Ge, W.65
Gong, F.66
Gu, Z.67
Guan, P.68
Heiman, T.J.69
Higgins, M.E.70
Ji, R.-R.71
Ke, Z.72
Ketchum, K.A.73
Lai, Z.74
Lei, Y.75
Li, Z.76
Li, J.77
Liang, Y.78
Lin, X.79
Lu, F.80
Merkulov, G.V.81
Milshina, N.82
Moore, H.M.83
Naik, A.K.84
Narayan, V.A.85
Neelam, B.86
Nusskern, D.87
Rusch, D.B.88
Salzberg, S.89
Shao, W.90
Shue, B.91
Sun, J.92
Wang, Z.Y.93
Wang, A.94
Wang, X.95
Wang, J.96
Wei, M.-H.97
Wides, R.98
Xiao, C.99
more..
-
3
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium. A haplotype map of the human genome. Nature. 2005;437:1299-1320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
4
-
-
69549110333
-
Health care provider and consumer awareness perceptions and use of direct-to-consumer personal genomic tests United States 2008
-
Kolor K, Liu T, St Pierre J, Khoury MJ. Health care provider and consumer awareness, perceptions, and use of direct-to-consumer personal genomic tests, United States, 2008. Genet Med. 2009;11:595.
-
(2009)
Genet Med
, vol.11
, pp. 595
-
-
Kolor, K.1
Liu, T.2
St Pierre, J.3
Khoury, M.J.4
-
5
-
-
72949132104
-
Factors of risk in the development of coronary heart disease: Six year follow-up experience: The Framingham Study
-
Kannel WB, Dawber TR, Kagan A, Revotskie N, Stokes J III. Factors of risk in the development of coronary heart disease: six year follow-up experience: the Framingham Study. Ann Intern Med. 1961;55:33-50.
-
(1961)
Ann Intern Med
, vol.55
, pp. 33-50
-
-
Kannel, W.B.1
Dawber, T.R.2
Kagan, A.3
Revotskie, N.4
Stokes Iii, J.5
-
6
-
-
34447619161
-
Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: Prospective open cohort study
-
Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, May M, Brindle P. Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study. BMJ. 2007;335:136.
-
(2007)
BMJ
, vol.335
, pp. 136
-
-
Hippisley-Cox, J.1
Coupland, C.2
Vinogradova, Y.3
Robson, J.4
May, M.5
Brindle, P.6
-
7
-
-
67649516627
-
Predicting the 30-year risk of cardiovascular disease: The Framingham Heart Study
-
Pencina MJ, D'Agostino RB Sr, Larson MG, Massaro JM, Vasan RS. Predicting the 30-year risk of cardiovascular disease: the Framingham Heart Study. Circulation. 2009;119:3078-3084.
-
(2009)
Circulation
, vol.119
, pp. 3078-3084
-
-
Pencina, M.J.1
Larson, M.G.2
Massaro, J.M.3
Vasan, R.S.4
-
8
-
-
57749210419
-
C-reactive protein and parental history improve global cardiovascular risk prediction: The Reynolds Risk Score for men
-
Ridker PM, Paynter NP, Rifai N, Gaziano JM, Cook NR. C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation. 2008;118: 2243-2251.
-
(2008)
Circulation
, vol.118
, pp. 2243-2251
-
-
Ridker, P.M.1
Paynter, N.P.2
Rifai, N.3
Gaziano, J.M.4
Cook, N.R.5
-
9
-
-
0032510639
-
Prediction of coronary heart disease using risk factor categories
-
Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97:1837-1847.
-
(1998)
Circulation
, vol.97
, pp. 1837-1847
-
-
Wilson, P.W.1
D'Agostino, R.B.2
Levy, D.3
Belanger, A.M.4
Silbershatz, H.5
Kannel, W.B.6
-
10
-
-
66649130580
-
Advances in measuring the effect of individual predictors of cardiovascular risk: The role of reclassification measures
-
Cook NR, Ridker PM. Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures. Ann Intern Med. 2009;150:795-802.
-
(2009)
Ann Intern Med
, vol.150
, pp. 795-802
-
-
Cook, N.R.1
Ridker, P.M.2
-
11
-
-
58749085039
-
Adverse consequences of the 50% misconception
-
Kannel WB, Vasan RS. Adverse consequences of the 50% misconception. Am J Cardiol. 2009;103:426-427.
-
(2009)
Am J Cardiol
, vol.103
, pp. 426-427
-
-
Kannel, W.B.1
Vasan, R.S.2
-
12
-
-
4444382796
-
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
-
INTERHEART Study Investigators
-
Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364:937-952.
-
(2004)
Lancet
, vol.364
, pp. 937-952
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
Dans, T.4
Avezum, A.5
Lanas, F.6
McQueen, M.7
Budaj, A.8
Pais, P.9
Varigos, J.10
Lisheng, L.11
-
13
-
-
0042697063
-
Prevalence of conventional risk factors in patients with coronary heart disease
-
Khot UN, Khot MB, Bajzer CT, Sapp SK, Ohman EM, Brener SJ, Ellis SG, Lincoff AM, Topol EJ. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA. 2003;290:898-904.
-
(2003)
JAMA
, vol.290
, pp. 898-904
-
-
Khot, U.N.1
Khot, M.B.2
Bajzer, C.T.3
Sapp, S.K.4
Ohman, E.M.5
Brener, S.J.6
Ellis, S.G.7
Lincoff, A.M.8
Topol, E.J.9
-
14
-
-
72249113124
-
Assessment of claims of improved prediction beyond the Framingham risk score
-
Tzoulaki I, Liberopoulos G, Ioannidis JP. Assessment of claims of improved prediction beyond the Framingham risk score. JAMA. 2009; 302:2345-2352.
-
(2009)
JAMA
, vol.302
, pp. 2345-2352
-
-
Tzoulaki, I.1
Liberopoulos, G.2
Ioannidis, J.P.3
-
15
-
-
66349111734
-
Criteria for evaluation of novel markers of cardiovascular risk: A scientific statement from the American Heart Association [published correction appears
-
American Heart Association Expert Panel on Subclinical Atherosclerotic Diseases and Emerging Risk Factors and the Stroke Council 119:e606] Circulation
-
Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, Go AS, Harrell FE Jr, Hong Y, Howard BV, Howard VJ, Hsue PY, Kramer CM, McConnell JP, Normand SL, O'Donnell CJ, Smith SC Jr, Wilson PW; American Heart Association Expert Panel on Subclinical Atherosclerotic Diseases and Emerging Risk Factors and the Stroke Council. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association [published correction appears in Circulation. 2009;119:e606]. Circulation. 2009; 119:2408-2416.
-
(2009)
Circulation
, vol.119
, pp. 2408-2416
-
-
Hlatky, M.A.1
Greenland, P.2
Arnett, D.K.3
Ballantyne, C.M.4
Criqui, M.H.5
Elkind, M.S.6
Go, A.S.7
Harrell Jr., F.E.8
Hong, Y.9
Howard, B.V.10
Howard, V.J.11
Hsue, P.Y.12
Kramer, C.M.13
McConnell, J.P.14
Normand, S.L.15
O'Donnell, C.J.16
Smith Jr., S.C.17
Wilson, P.W.18
-
16
-
-
33846996345
-
Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: The Reynolds Risk Score
-
Ridker PM, Buring JE, Rifai N, Cook NR. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA. 2007;297:611-619.
-
(2007)
JAMA
, vol.297
, pp. 611-619
-
-
Ridker, P.M.1
Buring, J.E.2
Rifai, N.3
Cook, N.R.4
-
17
-
-
77952499034
-
General Cardiovascular Risk Profile identifies advanced coronary artery calcium and is improved by family history: The Multiethnic Study of Atherosclerosis
-
Scheuner MT, Setodji CM, Pankow JS, Blumenthal RS, Keeler E. General Cardiovascular Risk Profile identifies advanced coronary artery calcium and is improved by family history: the Multiethnic Study of Atherosclerosis. Circ Cardiovasc Genet. 2010;3:97-105.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 97-105
-
-
Scheuner, M.T.1
Setodji, C.M.2
Pankow, J.S.3
Blumenthal, R.S.4
Keeler, E.5
-
18
-
-
2342486731
-
Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: A prospective study of parents and offspring
-
Lloyd-Jones DM, Nam BH, D'Agostino RB Sr, Levy D, Murabito JM, Wang TJ, Wilson PW, O'Donnell CJ. Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring. JAMA. 2004;291:2204-2211.
-
(2004)
JAMA
, vol.291
, pp. 2204-2211
-
-
Lloyd-Jones, D.M.1
Nam, B.H.2
Levy, D.3
Murabito, J.M.4
Wang, T.J.5
Wilson, P.W.6
O'Donnell, C.J.7
-
19
-
-
29544440820
-
Sibling cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults
-
Murabito JM, Pencina MJ, Nam BH, D'Agostino RB Sr, Wang TJ, Lloyd-Jones D, Wilson PW, O'Donnell CJ. Sibling cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults. JAMA. 2005;294:3117-3123.
-
(2005)
JAMA
, vol.294
, pp. 3117-3123
-
-
Murabito, J.M.1
Pencina, M.J.2
Nam, B.H.3
Wang, T.J.4
Lloyd-Jones, D.5
Wilson, P.W.6
O'Donnell, C.J.7
-
20
-
-
20044382611
-
Distinct heritable patterns of angiographic coronary artery disease in families with myo-cardial infarction
-
Fischer M, Broeckel U, Holmer S, Baessler A, Hengstenberg C, Mayer B, Erdmann J, Klein G, Riegger G, Jacob HJ, Schunkert H. Distinct heritable patterns of angiographic coronary artery disease in families with myo-cardial infarction. Circulation. 2005 111 855-862.
-
(2005)
Circulation
, vol.111
, pp. 855-862
-
-
Fischer, M.1
Broeckel, U.2
Holmer, S.3
Baessler, A.4
Hengstenberg, C.5
Mayer, B.6
Erdmann, J.7
Klein, G.8
Riegger, G.9
Jacob, H.J.10
Schunkert, H.11
-
21
-
-
0018901060
-
Genetic- e-pidemiologic study of early-onset ischemic heart disease
-
Nora JJ, Lortscher RH, Spangler RD, Nora AH, Kimberling WJ. Genetic- e-pidemiologic study of early-onset ischemic heart disease. Circulation. 1980; 61:503-508.
-
(1980)
Circulation
, vol.61
, pp. 503-508
-
-
Nora, J.J.1
Lortscher, R.H.2
Spangler, R.D.3
Nora, A.H.4
Kimberling, W.J.5
-
22
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, Hinds DA, Pennacchio LA, Tybjaerg-Hansen A, Folsom AR, Boer-winkle E, Hobbs HH, Cohen JC. A common allele on chromosome 9 associated with coronary heart disease. Science. 2007;316:1488-1491.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
Cox, D.R.6
Hinds, D.A.7
Pennacchio, L.A.8
Tybjaerg-Hansen, A.9
Folsom, A.R.10
Boer-Winkle, E.11
Hobbs, H.H.12
Cohen, J.C.13
-
23
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T, Jonasdottir A, Sigurdsson A, Baker A, Palsson A, Masson G, Gudb-jartsson DF, Magnusson KP, Andersen K, Levey AI, Backman VM, Matthiasdottir S, Jonsdottir T, Palsson S, Einarsdottir H, Gunnarsdottir S, Gylfason A, Vaccarino V, Hooper WC, Reilly MP, Granger CB, Austin H, Rader DJ, Shah SH, Quyyumi AA, Gulcher JR, Thorgeirsson G, Thorsteinsdottir U, Kong A, Stefansson K. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science. 2007; 316:1491-1493.
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
Gretarsdottir, S.4
Blondal, T.5
Jonasdottir, A.6
Sigurdsson, A.7
Baker, A.8
Palsson, A.9
Masson, G.10
Gudb-Jartsson, D.F.11
Magnusson, K.P.12
Andersen, K.13
Levey, A.I.14
Backman, V.M.15
Matthiasdottir, S.16
Jonsdottir, T.17
Palsson, S.18
Einarsdottir, H.19
Gunnarsdottir, S.20
Gylfason, A.21
Vaccarino, V.22
Hooper, W.C.23
Reilly, M.P.24
Granger, C.B.25
Austin, H.26
Rader, D.J.27
Shah, S.H.28
Quyyumi, A.A.29
Gulcher, J.R.30
Thorgeirsson, G.31
Thorsteinsdottir, U.32
Kong, A.33
Stefansson, K.34
more..
-
24
-
-
41649085340
-
Repeated Replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease
-
for the Cardiogenics Consortium
-
Schunkert H, Gotz A, Braund P, McGinnis R, Tregouet D-A, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJR, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann H-E, Konig IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ; for the Cardiogenics Consortium. Repeated Replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation. 2008;117:1675-1684.
-
(2008)
Circulation
, vol.117
, pp. 1675-1684
-
-
Schunkert, H.1
Gotz, A.2
Braund, P.3
McGinnis, R.4
Tregouet, D.-A.5
Mangino, M.6
Linsel-Nitschke, P.7
Cambien, F.8
Hengstenberg, C.9
Stark, K.10
Blankenberg, S.11
Tiret, L.12
Ducimetiere, P.13
Keniry, A.14
Mjr, G.15
Schreiber, S.16
El Mokhtari, N.E.17
Hall, A.S.18
Dixon, R.J.19
Goodall, A.H.20
Liptau, H.21
Pollard, H.22
Schwarz, D.F.23
Hothorn, L.A.24
Wichmann, H.-E.25
Konig, I.R.26
Fischer, M.27
Meisinger, C.28
Ouwehand, W.29
Deloukas, P.30
Thompson, J.R.31
Erdmann, J.32
Ziegler, A.33
Samani, N.J.34
more..
-
25
-
-
77949775636
-
Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
-
Visel A, Zhu Y, May D, Afzal V, Gong E, Attanasio C, Blow MJ, Cohen JC, Rubin EM, Pennacchio LA. Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature. 2010;464:409-412.
-
(2010)
Nature
, vol.464
, pp. 409-412
-
-
Visel, A.1
Zhu, Y.2
May, D.3
Afzal, V.4
Gong, E.5
Attanasio, C.6
Blow, M.J.7
Cohen, J.C.8
Rubin, E.M.9
Pennacchio, L.A.10
-
26
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
27
-
-
61349177857
-
New susceptibility locus for coronary artery disease on chromosome 3q22.3
-
Erdmann J, Groszhennig A, Braund PS, Konig IR, Hengstenberg C, Hall AS, Linsel-Nitschke P, Kathiresan S, Wright B, Tregouet D-A, Cambien F, Bruse P, Aherrahrou Z, Wagner AK, Stark K, Schwartz SM, Salomaa V, Elosua R, Melander O, Voight BF, O'Donnell CJ, Peltonen L, Sis-covick DS, Altshuler D, Merlini PA, Peyvandi F, Bernardinelli L, Ard-issino D, Schillert A, Blankenberg S, Zeller T, Wild P, Schwarz DF, Tiret L, Perret C, Schreiber S, Mokhtari NEE, Schafer A, Marz W, Renner W, Bugert P, Kluter H, Schrezenmeir J, Rubin D, Ball SG, Balmforth AJ, Wichmann HE, Meitinger T, Fischer M, Meisinger C, Baumert J, Peters A, Ouwehand WH, Deloukas P, Thompson JR, Ziegler A, Samani NJ, Schunkert H. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet. 2009;41:280-282.
-
(2009)
Nat Genet
, vol.41
, pp. 280-282
-
-
Erdmann, J.1
Groszhennig, A.2
Braund, P.S.3
Konig, I.R.4
Hengstenberg, C.5
Hall, A.S.6
Linsel-Nitschke, P.7
Kathiresan, S.8
Wright, B.9
Tregouet, D.-A.10
Cambien, F.11
Bruse, P.12
Aherrahrou, Z.13
Wagner, A.K.14
Stark, K.15
Schwartz, S.M.16
Salomaa, V.17
Elosua, R.18
Melander, O.19
Voight, B.F.20
O'Donnell, C.J.21
Peltonen, L.22
Sis-Covick, D.S.23
Altshuler, D.24
Merlini, P.A.25
Peyvandi, F.26
Bernardinelli, L.27
Ard-Issino, D.28
Schillert, A.29
Blankenberg, S.30
Zeller, T.31
Wild, P.32
Schwarz, D.F.33
Tiret, L.34
Perret, C.35
Schreiber, S.36
Nee, M.37
Schafer, A.38
Marz, W.39
Renner, W.40
Bugert, P.41
Kluter, H.42
Schrezenmeir, J.43
Rubin, D.44
Ball, S.G.45
Balmforth, A.J.46
Wichmann, H.E.47
Meitinger, T.48
Fischer, M.49
Meisinger, C.50
Baumert, J.51
Peters, A.52
Ouwehand, W.H.53
Deloukas, P.54
Thompson, J.R.55
Ziegler, A.56
Samani, N.J.57
Schunkert, H.58
more..
-
28
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Myocardial Infarction Genetics Consortium; Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M, Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Yee J, Friedlander Y, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Meigs JB, Williams G, Nathan DM, MacRae CA, Havulinna AS, Berglund G, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Daly MJ, Nemesh J, Korn JM, McCarroll SA, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, Thompson JR, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Hall AS; Wellcome Trust Case Control Consortium; Linsel-Nitschke P, Lieb W, Ziegler A, Konig I, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Ouwehand W, Deloukas P, Scholz M, Cambien F, Li M, Chen Z, Wilensky R, Matthai W, Qasim A, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein SE, Scheffold T, Berger K, Huge A, Martinelli N, Olivieri O, Corrocher R, McKeown P, Erdmann E, Konig IR, Holm H, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Do R, Xie C, Siscovick D. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009;41:334-341.
-
(2009)
Nat Genet
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
Voight, B.F.2
Purcell, S.3
Musunuru, K.4
Ardissino, D.5
Mannucci, P.M.6
Anand, S.7
Engert, J.C.8
Samani, N.J.9
Schunkert, H.10
Erdmann, J.11
Reilly, M.P.12
Rader, D.J.13
Morgan, T.14
Spertus, J.A.15
Stoll, M.16
Girelli, D.17
McKeown, P.P.18
Patterson, C.C.19
Siscovick, D.S.20
O'Donnell, C.J.21
Elosua, R.22
Peltonen, L.23
Salomaa, V.24
Schwartz, S.M.25
Melander, O.26
Altshuler, D.27
Merlini, P.A.28
Berzuini, C.29
more..
-
29
-
-
34547623750
-
WTCCC and the Cardiogenics Consortium. Genomewide association analysis of coronary artery disease
-
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann H-E, Barrett JH, Konig IR, Stevens SE, Szymczak S, Tregouet D-A, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H; WTCCC and the Cardiogenics Consortium. Genomewide association analysis of coronary artery disease. N Engl J Med. 2007;357:443-453.
-
(2007)
N Engl J Med
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
Dixon, R.J.7
Meitinger, T.8
Braund, P.9
Wichmann, H.-E.10
Barrett, J.H.11
Konig, I.R.12
Stevens, S.E.13
Szymczak, S.14
Tregouet, D.-A.15
Iles, M.M.16
Pahlke, F.17
Pollard, H.18
Lieb, W.19
Cambien, F.20
Fischer, M.21
Ouwehand, W.22
Blankenberg, S.23
Balmforth, A.J.24
Baessler, A.25
Ball, S.G.26
Strom, T.M.27
Braenne, I.28
Gieger, C.29
Deloukas, P.30
Tobin, M.D.31
Ziegler, A.32
Thompson, J.R.33
Schunkert, H.34
more..
-
30
-
-
61349137526
-
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
-
Wellcome Trust Case Control Consortium; Cardiogenics Consortium Ziegler
-
Tregouet DA, Konig IR, Erdmann J, Munteanu A, Braund PS, Hall AS, Grosshennig A, Linsel-Nitschke P, Perret C, DeSuremain M, Meitinger T, Wright BJ, Preuss M, Balmforth AJ, Ball SG, Meisinger C, Germain C, Evans A, Arveiler D, Luc G, Ruidavets JB, Morrison C, van der Harst P, Schreiber S, Neureuther K, Schafer A, Bugert P, El Mokhtari NE, Schre-zenmeir J, Stark K, Rubin D, Wichmann HE, Hengstenberg C, Ouwehand W, Wellcome Trust Case Control Consortium; Cardiogenics Consortium, Ziegler A, Tiret L, Thompson JR, Cambien F, Schunkert H, Samani NJ. Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet. 2009;41:283-285.
-
(2009)
Nat Genet
, vol.41
, pp. 283-285
-
-
Tregouet, D.A.1
Konig, I.R.2
Erdmann, J.3
Munteanu, A.4
Braund, P.S.5
Hall, A.S.6
Grosshennig, A.7
Linsel-Nitschke, P.8
Perret, C.9
Desuremain, M.10
Meitinger, T.11
Wright, B.J.12
Preuss, M.13
Balmforth, A.J.14
Ball, S.G.15
Meisinger, C.16
Germain, C.17
Evans, A.18
Arveiler, D.19
Luc, G.20
Ruidavets, J.B.21
Morrison, C.22
Van Der Harst, P.23
Schreiber, S.24
Neureuther, K.25
Schafer, A.26
Bugert, P.27
El Mokhtari, N.E.28
Schre-Zenmeir, J.29
Stark, K.30
Rubin, D.31
Wichmann, H.E.32
Hengstenberg, C.33
Ouwehand, W.34
more..
-
31
-
-
61349089164
-
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
-
Gudbjartsson DF, Bjornsdottir US, Halapi E, Helgadottir A, Sulem P, Jonsdottir GM, Thorleifsson G, Helgadottir H, Steinthorsdottir V, Ste-fansson H, Williams C, Hui J, Beilby J, Warrington NM, James A, Palmer LJ, Koppelman GH, Heinzmann A, Krueger M, Boezen HM, Wheatley A, Altmuller J, Shin HD, Uh S-T, Cheong HS, Jonsdottir B, Gislason D, Park C-S, Rasmussen LM, Porsbjerg C, Hansen JW, Backer V, Werge T, Janson C, Jonsson U-B, Ng MCY, Chan J, So WY, Ma R, Shah SH, Granger CB, Quyyumi AA, Levey AI, Vaccarino V, Reilly MP, Rader DJ, Williams MJA, van Rij AM, Jones GT, Trabetti E, Malerba G, Pignatti PF, Boner A, Pescollderungg L, Girelli D, Olivieri O, Martinelli N, Ludviksson BR, Ludviksdottir D, Eyjolfsson GI, Arnar D, Thor-geirsson G, Deichmann K, Thompson PJ, Wjst M, Hall IP, Postma DS, Gislason T, Gulcher J, Kong A, Jonsdottir I, Thorsteinsdottir U, Ste-fansson K. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet. 2009;41:342-347.
-
(2009)
Nat Genet
, vol.41
, pp. 342-347
-
-
Gudbjartsson, D.F.1
Bjornsdottir, U.S.2
Halapi, E.3
Helgadottir, A.4
Sulem, P.5
Jonsdottir, G.M.6
Thorleifsson, G.7
Helgadottir, H.8
Steinthorsdottir, V.9
Ste-Fansson, H.10
Williams, C.11
Hui, J.12
Beilby, J.13
Warrington, N.M.14
James, A.15
Palmer, L.J.16
Koppelman, G.H.17
Heinzmann, A.18
Krueger, M.19
Boezen, H.M.20
Wheatley, A.21
Altmuller, J.22
Shin, H.D.23
Uh, S.-T.24
Cheong, H.S.25
Jonsdottir, B.26
Gislason, D.27
Park, C.-S.28
Rasmussen, L.M.29
Porsbjerg, C.30
Hansen, J.W.31
Backer, V.32
Werge, T.33
Janson, C.34
Jonsson, U.-B.35
McY, N.36
Chan, J.37
So, W.Y.38
Ma, R.39
Shah, S.H.40
Granger, C.B.41
Quyyumi, A.A.42
Levey, A.I.43
Vaccarino, V.44
Reilly, M.P.45
Rader, D.J.46
Mja, W.47
Van Rij, A.M.48
Jones, G.T.49
Trabetti, E.50
Malerba, G.51
Pignatti, P.F.52
Boner, A.53
Pescollderungg, L.54
Girelli, D.55
Olivieri, O.56
Martinelli, N.57
Ludviksson, B.R.58
Ludviksdottir, D.59
Eyjolfsson, G.I.60
Arnar, D.61
Thor-Geirsson, G.62
Deichmann, K.63
Thompson, P.J.64
Wjst, M.65
Hall, I.P.66
Postma, D.S.67
Gislason, T.68
Gulcher, J.69
Kong, A.70
Jonsdottir, I.71
Thorsteinsdottir, U.72
Ste-Fansson, K.73
more..
-
32
-
-
68249107559
-
A genome-wide association study of hypertension and blood pressure in African Americans
-
Adeyemo A, Gerry N, Chen G, Herbert A, Doumatey A, Huang H, Zhou J, Lashley K, Chen Y, Christman M, Rotimi C. A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet. 2009;5:e1000564.
-
(2009)
PLoS Genet
, vol.5
-
-
Adeyemo, A.1
Gerry, N.2
Chen, G.3
Herbert, A.4
Doumatey, A.5
Huang, H.6
Zhou, J.7
Lashley, K.8
Chen, Y.9
Christman, M.10
Rotimi, C.11
-
33
-
-
67349208839
-
Genome-wide association study of blood pressure and hypertension
-
Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Kottgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FUS, Smith AV, Taylor K, Scharpf RB, Hwang S-J, Sijbrands EJG, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JCM, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009;41:677-687.
-
(2009)
Nat Genet
, vol.41
, pp. 677-687
-
-
Levy, D.1
Ehret, G.B.2
Rice, K.3
Verwoert, G.C.4
Launer, L.J.5
Dehghan, A.6
Glazer, N.L.7
Morrison, A.C.8
Johnson, A.D.9
Aspelund, T.10
Aulchenko, Y.11
Lumley, T.12
Kottgen, A.13
Vasan, R.S.14
Rivadeneira, F.15
Eiriksdottir, G.16
Guo, X.17
Arking, D.E.18
Mitchell, G.F.19
Fus, M.20
Smith, A.V.21
Taylor, K.22
Scharpf, R.B.23
Hwang, S.-J.24
Ejg, S.25
Bis, J.26
Harris, T.B.27
Ganesh, S.K.28
O'Donnell, C.J.29
Hofman, A.30
Rotter, J.I.31
Coresh, J.32
Benjamin, E.J.33
Uitterlinden, A.G.34
Heiss, G.35
Fox, C.S.36
Jcm, W.37
Boerwinkle, E.38
Wang, T.J.39
Gudnason, V.40
Larson, M.G.41
Chakravarti, A.42
Psaty, B.M.43
Van Duijn, C.M.44
more..
-
34
-
-
67349085063
-
Genome-wide association study identifies eight loci associated with blood pressure
-
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw K-T, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan Ja, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Doring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen A-L, McCarthy MI, O'Reilly PF,Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvanen A-C, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dorr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Volker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Volzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin M-R, Mooser V, Melander O, Loos RJF, Elliott P, Abecasis GR, Caulfield M, Munroe PB. Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet. 2009;41:666-676.
-
(2009)
Nat Genet
, vol.41
, pp. 666-676
-
-
Newton-Cheh, C.1
Johnson, T.2
Gateva, V.3
Tobin, M.D.4
Bochud, M.5
Coin, L.6
Najjar, S.S.7
Zhao, J.H.8
Heath, S.C.9
Eyheramendy, S.10
Papadakis, K.11
Voight, B.F.12
Scott, L.J.13
Zhang, F.14
Farrall, M.15
Tanaka, T.16
-
35
-
-
58149161560
-
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Doring A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L; ENGAGE Consortium. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet. 2009;41: 47-55.
-
(2009)
Nat Genet
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
Ripatti, S.2
Lindqvist, I.3
Boomsma, D.4
Heid, I.M.5
Pramstaller, P.P.6
Penninx, B.W.7
Janssens, A.C.8
Wilson, J.F.9
Spector, T.10
Martin, N.G.11
Pedersen, N.L.12
Kyvik, K.O.13
Kaprio, J.14
Hofman, A.15
Freimer, N.B.16
Jarvelin, M.R.17
Gyllensten, U.18
Campbell, H.19
Rudan, I.20
Johansson, A.21
Marroni, F.22
Hayward, C.23
Vitart, V.24
Jonasson, I.25
Pattaro, C.26
Wright, A.27
Hastie, N.28
Pichler, I.29
Hicks, A.A.30
Falchi, M.31
Willemsen, G.32
Hottenga, J.J.33
De Geus, E.J.34
Montgomery, G.W.35
Whitfield, J.36
Magnusson, P.37
Saharinen, J.38
Perola, M.39
Silander, K.40
Isaacs, A.41
Sijbrands, E.J.42
Uitterlinden, A.G.43
Witteman, J.C.44
Oostra, B.A.45
Elliott, P.46
Ruokonen, A.47
Sabatti, C.48
Gieger, C.49
Meitinger, T.50
Kronenberg, F.51
Doring, A.52
Wichmann, H.E.53
Smit, J.H.54
McCarthy, M.I.55
Van Duijn, C.M.56
Peltonen, L.57
more..
-
36
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet. 2009;41:56-65.
-
(2009)
Nat Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
Demissie, S.4
Musunuru, K.5
Schadt, E.E.6
Kaplan, L.7
Bennett, D.8
Li, Y.9
Tanaka, T.10
Voight, B.F.11
Bonnycastle, L.L.12
Jackson, A.U.13
Crawford, G.14
Surti, A.15
Guiducci, C.16
Burtt, N.P.17
Parish, S.18
Clarke, R.19
Zelenika, D.20
Kubalanza, K.A.21
Morken, M.A.22
Scott, L.J.23
Stringham, H.M.24
Galan, P.25
Swift, A.J.26
Kuusisto, J.27
Bergman, R.N.28
Sundvall, J.29
Laakso, M.30
Ferrucci, L.31
Scheet, P.32
Sanna, S.33
Uda, M.34
Yang, Q.35
Lunetta, K.L.36
Dupuis, J.37
De Bakker, P.I.38
O'Donnell, C.J.39
Chambers, J.C.40
Kooner, J.S.41
Hercberg, S.42
Meneton, P.43
Lakatta, E.G.44
Scuteri, A.45
Schlessinger, D.46
Tuomilehto, J.47
Collins, F.S.48
Groop, L.49
Altshuler, D.50
Collins, R.51
Lathrop, G.M.52
Melander, O.53
Salomaa, V.54
Peltonen, L.55
Orho-Melander, M.56
Ordovas, J.M.57
Boehnke, M.58
Abecasis, G.R.59
Mohlke, K.L.60
Cupples, L.A.61
more..
-
37
-
-
58149159573
-
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
-
Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA, Varilo T, Kaakinen M, Sovio U, Ruokonen A, Laitinen J, Jakkula E, Coin L, Hoggart C, Collins A, Turunen H, Gabriel S, Elliot P, McCarthy MI, Daly MJ, Jarvelin MR, Freimer NB, Peltonen L. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet. 2009;41:35-46.
-
(2009)
Nat Genet
, vol.41
, pp. 35-46
-
-
Sabatti, C.1
Service, S.K.2
Hartikainen, A.L.3
Pouta, A.4
Ripatti, S.5
Brodsky, J.6
Jones, C.G.7
Zaitlen, N.A.8
Varilo, T.9
Kaakinen, M.10
Sovio, U.11
Ruokonen, A.12
Laitinen, J.13
Jakkula, E.14
Coin, L.15
Hoggart, C.16
Collins, A.17
Turunen, H.18
Gabriel, S.19
Elliot, P.20
McCarthy, M.I.21
Daly, M.J.22
Jarvelin, M.R.23
Freimer, N.B.24
Peltonen, L.25
more..
-
39
-
-
34247144499
-
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
-
Morgan TM, Krumholz HM, Lifton RP, Spertus JA. Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA. 2007;297:1551-1561.
-
(2007)
JAMA
, vol.297
, pp. 1551-1561
-
-
Morgan, T.M.1
Krumholz, H.M.2
Lifton, R.P.3
Spertus, J.A.4
-
40
-
-
34247147948
-
Genetic effects versus bias for candidate polymorphisms in myocardial infarction: Case study and overview of large-scale evidence
-
Ntzani EE, Rizos EC, Ioannidis JP. Genetic effects versus bias for candidate polymorphisms in myocardial infarction: case study and overview of large-scale evidence. Am J Epidemiol. 2007;165:973-984.
-
(2007)
Am J Epidemiol
, vol.165
, pp. 973-984
-
-
Ntzani, E.E.1
Rizos, E.C.2
Ioannidis, J.P.3
-
41
-
-
65949107547
-
Common genetic variation and human traits
-
Goldstein DB. Common genetic variation and human traits. N Engl J Med. 2009;360:1696-1698.
-
(2009)
N Engl J Med
, vol.360
, pp. 1696-1698
-
-
Goldstein, D.B.1
-
42
-
-
77149120471
-
Association between a literature-based genetic risk score and cardiovascular events in women
-
Paynter NP, Chasman DI, Pare G, Buring JE, Cook NR, Miletich JP, Ridker PM. Association between a literature-based genetic risk score and cardiovascular events in women. JAMA.303:631-637.
-
JAMA.303
, pp. 631-637
-
-
Paynter, N.P.1
Chasman, D.I.2
Pare, G.3
Buring, J.E.4
Cook, N.R.5
Miletich, J.P.6
Ridker, P.M.7
-
43
-
-
58749087343
-
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3
-
Paynter NP, Chasman DI, Buring JE, Shiffman D, Cook NR, Ridker PM. Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3. Ann Intern Med. 2009;150: 65-72.
-
(2009)
Ann Intern Med
, vol.150
, pp. 65-72
-
-
Paynter, N.P.1
Chasman, D.I.2
Buring, J.E.3
Shiffman, D.4
Cook, N.R.5
Ridker, P.M.6
-
44
-
-
70449513058
-
Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study
-
Brautbar A, Ballantyne CM, Lawson K, Nambi V, Chambless L, Folsom AR, Willerson JT, Boerwinkle E. Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study. Circ Cardiovasc Genet. 2009;2: 279-285.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 279-285
-
-
Brautbar, A.1
Ballantyne, C.M.2
Lawson, K.3
Nambi, V.4
Chambless, L.5
Folsom, A.R.6
Willerson, J.T.7
Boerwinkle, E.8
-
45
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
Kathiresan S, Melander O, Anevski D, Guiducci C, Burtt NP, Roos C, Hirschhorn JN, Berglund G, Hedblad B, Groop L, Altshuler DM, Newton-Cheh C, Orho-Melander M. Polymorphisms associated with cholesterol and risk of cardiovascular events. N Engl J Med. 2008;358: 1240-1249.
-
(2008)
N Engl J Med
, vol.358
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
Roos, C.6
Hirschhorn, J.N.7
Berglund, G.8
Hedblad, B.9
Groop, L.10
Altshuler, D.M.11
Newton-Cheh, C.12
Orho-Melander, M.13
-
46
-
-
40449095630
-
Chromosome 9p21.3 coronary heart disease locus geno-type and prospective risk of CHD in healthy middle-aged men
-
Talmud PJ, Cooper JA, Palmen J, Lovering R, Drenos F, Hingorani AD, Humphries SE. Chromosome 9p21.3 coronary heart disease locus geno-type and prospective risk of CHD in healthy middle-aged men. Clin Chem. 2008;54:467-474.
-
(2008)
Clin Chem
, vol.54
, pp. 467-474
-
-
Talmud, P.J.1
Cooper, J.A.2
Palmen, J.3
Lovering, R.4
Drenos, F.5
Hingorani, A.D.6
Humphries, S.E.7
-
47
-
-
34547555885
-
Prediction of coronary heart disease risk using a genetic risk score: The Atherosclerosis Risk in Communities Study
-
Morrison AC, Bare LA, Chambless LE, Ellis SG, Malloy M, Kane JP, Pankow JS, Devlin JJ, Willerson JT, Boerwinkle E. Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol. 2007;166:28-35.
-
(2007)
Am J Epidemiol
, vol.166
, pp. 28-35
-
-
Morrison, A.C.1
Bare, L.A.2
Chambless, L.E.3
Ellis, S.G.4
Malloy, M.5
Kane, J.P.6
Pankow, J.S.7
Devlin, J.J.8
Willerson, J.T.9
Boerwinkle, E.10
-
48
-
-
33846032339
-
Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men
-
Humphries SE, Cooper JA, Talmud PJ, Miller GJ. Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men. Clin Chem. 2007; 53:8-16.
-
(2007)
Clin Chem
, vol.53
, pp. 8-16
-
-
Humphries, S.E.1
Cooper, J.A.2
Talmud, P.J.3
Miller, G.J.4
-
49
-
-
77549087690
-
A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study
-
Junyent M, Tucker KL, Shen J, Lee YC, Smith CE, Mattei J, Lai CQ, Parnell LD, Ordovas JM. A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study. Nutr Metab Cardiovasc Dis. 2010;20: 157-164.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, pp. 157-164
-
-
Junyent, M.1
Tucker, K.L.2
Shen, J.3
Lee, Y.C.4
Smith, C.E.5
Mattei, J.6
Lai, C.Q.7
Parnell, L.D.8
Ordovas, J.M.9
-
50
-
-
42949160705
-
Genetic predisposition, nongenetic risk factors, and coronary infarct
-
Trichopoulou A, Yiannakouris N, Bamia C, Benetou V, Trichopoulos D, Ordovas JM. Genetic predisposition, nongenetic risk factors, and coronary infarct. Arch Intern Med. 2008;168:891-896.
-
(2008)
Arch Intern Med
, vol.168
, pp. 891-896
-
-
Trichopoulou, A.1
Yiannakouris, N.2
Bamia, C.3
Benetou, V.4
Trichopoulos, D.5
Ordovas, J.M.6
-
51
-
-
0037069779
-
Prediction of the risk of myocardial infarction from polymorphisms in candidate genes
-
Yamada Y, Izawa H, Ichihara S, Takatsu F, Ishihara H, Hirayama H, Sone T, Tanaka M, Yokota M. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med. 2002; 347:1916-1923.
-
(2002)
N Engl J Med
, vol.347
, pp. 1916-1923
-
-
Yamada, Y.1
Izawa, H.2
Ichihara, S.3
Takatsu, F.4
Ishihara, H.5
Hirayama, H.6
Sone, T.7
Tanaka, M.8
Yokota, M.9
-
52
-
-
71849106791
-
Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers
-
Ioannidis JP. Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers. Circ Cardiovasc Genet. 2009;2:7-15.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 7-15
-
-
Ioannidis, J.P.1
-
53
-
-
70350183757
-
Genetic scoring analysis a way forward in genome wide association studies?
-
Amin N, van Duijn CM, Janssens AC. Genetic scoring analysis: a way forward in genome wide association studies? Eur J Epidemiol. 2009;24: 585-587.
-
(2009)
Eur J Epidemiol
, vol.24
, pp. 585-587
-
-
Amin, N.1
Van Duijn, C.M.2
Janssens, A.C.3
-
54
-
-
2342571696
-
Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker
-
Pepe MS, Janes H, Longton G, Leisenring W, Newcomb P. Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker. Am J Epidemiol. 2004;159:882-890.
-
(2004)
Am J Epidemiol
, vol.159
, pp. 882-890
-
-
Pepe, M.S.1
Janes, H.2
Longton, G.3
Leisenring, W.4
Newcomb, P.5
-
55
-
-
50549104256
-
Why most discovered true associations are inflated
-
Ioannidis JP. Why most discovered true associations are inflated. Epidemiology. 2008;19:640-648.
-
(2008)
Epidemiology
, vol.19
, pp. 640-648
-
-
Ioannidis, J.P.1
-
56
-
-
34147119077
-
Overcoming the winner's curse: Estimating penetrance parameters from case-control data
-
Zollner S, Pritchard JK. Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet. 2007; 80:605-615.
-
(2007)
Am J Hum Genet
, vol.80
, pp. 605-615
-
-
Zollner, S.1
Pritchard, J.K.2
-
57
-
-
41049087605
-
Heterogeneity in meta-anal-yses of genome-wide association investigations
-
Ioannidis JP, Patsopoulos NA, Evangelou E. Heterogeneity in meta-anal-yses of genome-wide association investigations. PLoS One. 2007;2:e841.
-
(2007)
PLoS One
, vol.2
-
-
Ioannidis, J.P.1
Patsopoulos, N.A.2
Evangelou, E.3
-
58
-
-
68949191441
-
Genome-based prediction of common diseases: Methodological considerations for future research
-
Janssens AC, van Duijn CM. Genome-based prediction of common diseases: methodological considerations for future research. Genome Med. 2009;1:20.
-
(2009)
Genome Med
, vol.1
, pp. 20
-
-
Janssens, A.C.1
Van Duijn, C.M.2
-
59
-
-
0021399798
-
Biased selection of controls for case-control analyses of cohort studies
-
Lubin JH, Gail MH. Biased selection of controls for case-control analyses of cohort studies. Biometrics. 1984;40:63-75.
-
(1984)
Biometrics
, vol.40
, pp. 63-75
-
-
Lubin, J.H.1
Gail, M.H.2
-
60
-
-
64549114613
-
A simulation study of control sampling methods for nested case-control studies of genetic and molecular biomarkers and prostate cancer progression
-
Wang MH, Shugart YY, Cole SR, Platz EA. A simulation study of control sampling methods for nested case-control studies of genetic and molecular biomarkers and prostate cancer progression. Cancer Epidemiol Biomarkers Prev. 2009;18:706-711.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 706-711
-
-
Wang, M.H.1
Shugart, Y.Y.2
Cole, S.R.3
Platz, E.A.4
-
61
-
-
70349089738
-
Lowering mortality in ST-elevation myocardial infarction and non-ST-elevation myocardial infarction: Key prehospital and emergency room treatment strategies
-
Goldstein P, Lapostolle F, Steg G, Danchin N, Assez N, Montalescot G, Charpentier S, Wiel E, Juliard JM. Lowering mortality in ST-elevation myocardial infarction and non-ST-elevation myocardial infarction: key prehospital and emergency room treatment strategies. Eur J Emerg Med. 2009;16:244-255.
-
(2009)
Eur J Emerg Med
, vol.16
, pp. 244-255
-
-
Goldstein, P.1
Lapostolle, F.2
Steg, G.3
Danchin, N.4
Assez, N.5
Montalescot, G.6
Charpentier, S.7
Wiel, E.8
Juliard, J.M.9
-
62
-
-
0032481832
-
Fatality outside hospital from acute coronary events in three British health districts 1994-5
-
United Kingdom Heart Attack Study Collaborative Group
-
Norris RM. Fatality outside hospital from acute coronary events in three British health districts, 1994-5: United Kingdom Heart Attack Study Collaborative Group. BMJ. 1998;316:1065-1070.
-
(1998)
BMJ
, vol.316
, pp. 1065-1070
-
-
Norris, R.M.1
-
63
-
-
60449094498
-
Heart disease and stroke statistics-2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Lloyd-Jones D. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:e21-e181.
-
(2009)
Circulation
, vol.119
-
-
Lloyd-Jones, D.1
-
64
-
-
58149156386
-
Cohort studies and the genetics of complex disease
-
Manolio TA. Cohort studies and the genetics of complex disease. Nat Genet. 2009;41:5-6.
-
(2009)
Nat Genet
, vol.41
, pp. 5-6
-
-
Manolio, T.A.1
-
65
-
-
33847109797
-
Use and misuse of the receiver operating characteristic curve in risk prediction
-
Cook NR. Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation. 2007;115:928-935.
-
(2007)
Circulation
, vol.115
, pp. 928-935
-
-
Cook, N.R.1
-
66
-
-
33747881836
-
Predictive testing for complex diseases using multiple genes: Fact or fiction?
-
Janssens AC, Aulchenko YS, Elefante S, Borsboom GJ, Steyerberg EW, van Duijn CM. Predictive testing for complex diseases using multiple genes: fact or fiction? Genet Med. 2006;8:395-400.
-
(2006)
Genet Med
, vol.8
, pp. 395-400
-
-
Janssens, A.C.1
Aulchenko, Y.S.2
Elefante, S.3
Borsboom, G.J.4
Steyerberg, E.W.5
Van Duijn, C.M.6
-
68
-
-
77649209124
-
The genetic interpretation of area under the ROC curve in genomic profiling
-
Wray NR, Yang J, Goddard ME, Visscher PM. The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet. 2010;6: e1000864.
-
(2010)
PLoS Genet
, vol.6
-
-
Wray, N.R.1
Yang, J.2
Goddard, M.E.3
Visscher, P.M.4
-
69
-
-
34948877698
-
Prediction of individual genetic risk to disease from genome-wide association studies
-
Wray NR, Goddard ME, Visscher PM. Prediction of individual genetic risk to disease from genome-wide association studies. Genome Res. 2007;17:1520-1528.
-
(2007)
Genome Res
, vol.17
, pp. 1520-1528
-
-
Wray, N.R.1
Goddard, M.E.2
Visscher, P.M.3
-
70
-
-
70349956433
-
Finding the missing heri-tability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Gutt-macher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM. Finding the missing heri-tability of complex diseases. Nature. 2009;461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
Cho, J.H.11
Gutt-Macher, A.E.12
Kong, A.13
Kruglyak, L.14
Mardis, E.15
Rotimi, C.N.16
Slatkin, M.17
Valle, D.18
Whittemore, A.S.19
Boehnke, M.20
Clark, A.G.21
Eichler, E.E.22
Gibson, G.23
Haines, J.L.24
MacKay, T.F.25
McCarroll, S.A.26
Visscher, P.M.27
more..
-
71
-
-
84984932946
-
Population genetics: Making sense out of sequence
-
Chakravarti A. Population genetics: making sense out of sequence. Nat Genet. 1999;21:56-60.
-
(1999)
Nat Genet
, vol.21
, pp. 56-60
-
-
Chakravarti, A.1
-
73
-
-
60149102060
-
Size matters: Just how big is BIG? Quantifying realistic sample size requirements for human genome epidemiology
-
Burton PR, Hansell AL, Fortier I, Manolio TA, Khoury MJ, Little J, Elliott P. Size matters: just how big is BIG? Quantifying realistic sample size requirements for human genome epidemiology. Int J Epidemiol. 2009;38:263-273.
-
(2009)
Int J Epidemiol
, vol.38
, pp. 263-273
-
-
Burton, P.R.1
Hansell, A.L.2
Fortier, I.3
Manolio, T.A.4
Khoury, M.J.5
Little, J.6
Elliott, P.7
-
74
-
-
57649243614
-
Genome-based prediction of common diseases: Advances and prospects
-
Janssens AC, van Duijn CM. Genome-based prediction of common diseases: advances and prospects. Hum Mol Genet. 2008;17:R166-R173.
-
(2008)
Hum Mol Genet
, vol.17
-
-
Janssens, A.C.1
Van Duijn, C.M.2
-
75
-
-
69449102525
-
Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk
-
Evans DM, Visscher PM, Wray NR. Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk. Hum Mol Genet. 2009;18:3525-3531.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3525-3531
-
-
Evans, D.M.1
Visscher, P.M.2
Wray, N.R.3
-
76
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-752.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O'Donovan, M.C.5
Sullivan, P.F.6
Sklar, P.7
-
77
-
-
40849097776
-
Heritability in the genomics era: Concepts and misconceptions
-
Visscher PM, Hill WG, Wray NR. Heritability in the genomics era: concepts and misconceptions. Nat Rev Genet. 2008;9:255-266.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 255-266
-
-
Visscher, P.M.1
Hill, W.G.2
Wray, N.R.3
-
78
-
-
33645760679
-
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings
-
Visscher PM, Medland SE, Ferreira MA, Morley KI, Zhu G, Cornes BK, Montgomery GW, Martin NG. Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet. 2006;2:e41.
-
(2006)
PLoS Genet
, vol.2
-
-
Visscher, P.M.1
Medland, S.E.2
Ferreira, M.A.3
Morley, K.I.4
Zhu, G.5
Cornes, B.K.6
Montgomery, G.W.7
Martin, N.G.8
-
79
-
-
58449085469
-
Invited commentary: From genome-wide association studies to gene-environment-wide interaction studies: Challenges and opportunities
-
Khoury MJ, Wacholder S. Invited commentary: from genome-wide association studies to gene-environment-wide interaction studies: challenges and opportunities. Am J Epidemiol. 2009;169:227-230.
-
(2009)
Am J Epidemiol
, vol.169
, pp. 227-230
-
-
Khoury, M.J.1
Wacholder, S.2
-
80
-
-
41649111313
-
Why study gene-environment interactions?
-
Ordovas JM, Tai ES. Why study gene-environment interactions? Curr Opin Lipidol. 2008;19:158-167.
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 158-167
-
-
Ordovas, J.M.1
Tai, E.S.2
-
81
-
-
67349166946
-
Detecting gene-gene interactions that underlie human diseases
-
Cordell HJ. Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet. 2009;10:392-404.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 392-404
-
-
Cordell, H.J.1
-
82
-
-
72849144434
-
Sequencing technologies: The next generation
-
Metzker ML. Sequencing technologies: the next generation. Nat Rev Genet. 2010;11:31-46.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 31-46
-
-
Metzker, M.L.1
-
83
-
-
52949141845
-
Integrated detection and population-genetic analysis of SNPs and copy number variation
-
McCarroll SA, Kuruvilla FG, Korn JM, Cawley S, Nemesh J, Wysoker A, Shapero MH, de Bakker PI, Maller JB, Kirby A, Elliott AL, Parkin M, Hubbell E, Webster T, Mei R, Veitch J, Collins PJ, Handsaker R, Lincoln S, Nizzari M, Blume J, Jones KW, Rava R, Daly MJ, Gabriel SB, Altshuler D. Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet. 2008;40:1166-1174.
-
(2008)
Nat Genet
, vol.40
, pp. 1166-1174
-
-
McCarroll, S.A.1
Kuruvilla, F.G.2
Korn, J.M.3
Cawley, S.4
Nemesh, J.5
Wysoker, A.6
Shapero, M.H.7
De Bakker, P.I.8
Maller, J.B.9
Kirby, A.10
Elliott, A.L.11
Parkin, M.12
Hubbell, E.13
Webster, T.14
Mei, R.15
Veitch, J.16
Collins, P.J.17
Handsaker, R.18
Lincoln, S.19
Nizzari, M.20
Blume, J.21
Jones, K.W.22
Rava, R.23
Daly, M.J.24
Gabriel, S.B.25
Altshuler, D.26
more..
-
84
-
-
76349083132
-
Large, rare chromosomal deletions associated with severe early-onset obesity
-
Bochukova EG, Huang N, Keogh J, Henning E, Purmann C, Blaszczyk K, Saeed S, Hamilton-Shield J, Clayton-Smith J, O'Rahilly S, Hurles ME, Farooqi IS. Large, rare chromosomal deletions associated with severe early-onset obesity. Nature. 2009;463:666-670.
-
(2009)
Nature
, vol.463
, pp. 666-670
-
-
Bochukova, E.G.1
Huang, N.2
Keogh, J.3
Henning, E.4
Purmann, C.5
Blaszczyk, K.6
Saeed, S.7
Hamilton-Shield, J.8
Clayton-Smith, J.9
O'Rahilly, S.10
Hurles, M.E.11
Farooqi, I.S.12
-
85
-
-
34047177395
-
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL
-
Romeo S, Pennacchio LA, Fu Y, Boerwinkle E, Tybjaerg-Hansen A, Hobbs HH, Cohen JC. Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet. 2007;39:513-516.
-
(2007)
Nat Genet
, vol.39
, pp. 513-516
-
-
Romeo, S.1
Pennacchio, L.A.2
Fu, Y.3
Boerwinkle, E.4
Tybjaerg-Hansen, A.5
Hobbs, H.H.6
Cohen, J.C.7
-
86
-
-
33947393565
-
Mapping the cancer genome: Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies
-
Collins FS, Barker AD. Mapping the cancer genome: pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies. Sci Am. 2007;296:50-57.
-
(2007)
Sci Am
, vol.296
, pp. 50-57
-
-
Collins, F.S.1
Barker, A.D.2
-
88
-
-
41649090385
-
"Deep phenotyping" characterizing populations in the era of genomics and systems biology
-
Tracy RP. "Deep phenotyping": characterizing populations in the era of genomics and systems biology. Curr Opin Lipidol. 2008;19:151-157.
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 151-157
-
-
Tracy, R.P.1
-
89
-
-
33745600563
-
Commentary: Grading the credibility of molecular evidence for complex diseases
-
Ioannidis JPA. Commentary: grading the credibility of molecular evidence for complex diseases. Int J Epidemiol. 2006;35:572-578.
-
(2006)
Int J Epidemiol
, vol.35
, pp. 572-578
-
-
Jpa, I.1
-
91
-
-
70349969413
-
Population-wide generalizability of genome-wide discovered associations
-
Ioannidis JP. Population-wide generalizability of genome-wide discovered associations. J Natl Cancer Inst. 2009;101:1297-1299.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1297-1299
-
-
Ioannidis, J.P.1
-
92
-
-
38849183343
-
The need for reorientation toward cost-effective prediction: Comments on "evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond"
-
by M.J. Pencina et al
-
Greenland S. The need for reorientation toward cost-effective prediction: comments on "Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond" by M.J. Pencina et al., Statistics in Medicine. Stat Med. 2008;27:199-206.
-
(2008)
Statistics in Medicine. Stat Med
, vol.27
, pp. 199-206
-
-
Greenland, S.1
-
93
-
-
65949099120
-
Genetic risk prediction are we there yet?
-
Kraft P, Hunter DJ. Genetic risk prediction: are we there yet? N Engl J Med. 2009;360:1701-1703.
-
(2009)
N Engl J Med
, vol.360
, pp. 1701-1703
-
-
Kraft, P.1
Hunter, D.J.2
-
94
-
-
0036578764
-
Polygenic susceptibility to breast cancer and implications for prevention
-
Pharoah PD, Antoniou A, Bobrow M, Zimmern RL, Easton DF, Ponder BA. Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet. 2002;31:33-36.
-
(2002)
Nat Genet
, vol.31
, pp. 33-36
-
-
Pharoah, P.D.1
Antoniou, A.2
Bobrow, M.3
Zimmern, R.L.4
Easton, D.F.5
Ponder, B.A.6
-
95
-
-
67649732906
-
Challenges of translating genetic tests into clinical and public health practice
-
Rogowski WH, Grosse SD, Khoury MJ. Challenges of translating genetic tests into clinical and public health practice. Nat Rev Genet. 2009;10: 489-495.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 489-495
-
-
Rogowski, W.H.1
Grosse, S.D.2
Khoury, M.J.3
-
96
-
-
15744374441
-
Clinical trial designs for predictive marker validation in cancer treatment trials
-
Sargent DJ, Conley BA, Allegra C, Collette L. Clinical trial designs for predictive marker validation in cancer treatment trials. J Clin Oncol. 2005;23:2020-2027.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2020-2027
-
-
Sargent, D.J.1
Conley, B.A.2
Allegra, C.3
Collette, L.4
-
97
-
-
70349125460
-
Pharmacogenetics in cardiovascular antithrombotic therapy
-
Maŕn F, González-Conejero R, Capranzano P, Bass TA, Roldán V, Angiolillo DJ. Pharmacogenetics in cardiovascular antithrombotic therapy. J Am Coll Cardiol. 2009;54:1041-1057.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 1041-1057
-
-
Maŕn, F.1
González-Conejero, R.2
Capranzano, P.3
Bass, T.A.4
Roldán, V.5
Angiolillo, D.J.6
|