Quantitative proteomics discloses MET expression in mitochondria as a direct target of MET kinase inhibitor in cancer cells

Molecular and Cellular Proteomics

Volumn 9, Issue 12, 2010, Pages 2629-2641

  Guo, Tiannan ^a,b   Zhu, Yi ^a   Gan, Chee Sian ^a   Lee, Sze Sing ^b   Zhu, Jiang ^c   Wang, Haixia ^c   Li, Xin ^a   Christensen, James ^d   Huang, Shiang ^c   Kon, Oi Lian ^b   Sze, Siu Kwan ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL PROTEIN; OXIDOREDUCTASE; SCATTER FACTOR RECEPTOR;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONFOCAL MICROSCOPY; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEOMICS; QUANTITATIVE ANALYSIS; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; GENE EXPRESSION PROFILING; HUMANS; MITOCHONDRIA; PROTEOMICS; PROTO-ONCOGENE PROTEINS C-MET; STOMACH NEOPLASMS; TANDEM MASS SPECTROMETRY;

EID: 78650076613     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M110.001776     Document Type: Article

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