An L-RNA-based aquaretic agent that inhibits vasopressin in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 13, 2006, Pages 5173-5178

  Purschke, Werner G ^a   Eulberg, Dirk ^a   Buchner, Klaus ^a   Vonhoff, Stefan ^a   Klussmann, Sven ^a  

^a NOXXON PHARMA AG   (Germany)

Author keywords

Aptamer; Congestive heart failure; Diureses; Spiegelmer; Water homeostasis

Indexed keywords

APTAMER; DIURETIC AGENT; NOX F37; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; VASOPRESSIN; VASOPRESSIN V1 RECEPTOR; VASOPRESSIN V2 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR DISEASE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DIURESIS; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HORMONE INHIBITION; IC 50; MALE; NEUROENDOCRINE DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; URINE VOLUME;

ANIMALS; BASE SEQUENCE; BINDING SITES; CARBOHYDRATE CONFORMATION; CELL LINE; KIDNEY; MALE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGORIBONUCLEOTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASOPRESSIN; RNA; SWINE; VASOPRESSINS;

ANIMALIA;

EID: 33645511033     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509663103     Document Type: Article

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