Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions

Journal of Biological Chemistry

Volumn 285, Issue 51, 2010, Pages 39922-39934

  Deng, Wenhan ^a   Garrett, Caroline ^a   Dombert, Benjamin ^a   Soura, Violetta ^a   Banks, Gareth ^b   Fisher, Elizabeth M C ^b   Van Der Brug, Marcel P ^c   Hafezparast, Majid ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTEROGRADE TRANSPORTS; BINDING DOMAIN; BIOCHEMICAL METHODS; CYTOPLASMIC DYNEIN; HEAVY CHAIN; HOMODIMERIZATION; IN-VIVO; KINESIN LIGHT CHAIN 1; KINESINS; MICROTUBULES; MOLECULAR MECHANISM; NEURODEGENERATION; NEURODEGENERATIVE; SENSORY NEURONS; UP-REGULATION;

AMINO ACIDS;

NEURONS;

ADENOSINE TRIPHOSPHATASE; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; KINESIN LIGHT CHAIN 1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MICROTUBULE; MOUSE; NERVE CELL; NERVE DEGENERATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ANIMALS; CYTOPLASMIC DYNEINS; MICE; MICE, MUTANT STRAINS; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NEURODEGENERATIVE DISEASES;

MUS;

EID: 78650047411     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.178087     Document Type: Article

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