Cytoplasmic dynein subunit heterogeneity: Implications for axonal transport

Journal of Neurocytology

Volumn 29, Issue 11-12, 2000, Pages 819-829

  Susalka, Stephen J ^a   Pfister, K Kevin ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN SUBUNIT;

ARTICLE; CELLULAR DISTRIBUTION; CYTOPLASM; HUMAN; MICROTUBULE; NERVE CELL; NERVE FIBER; NERVE FIBER TRANSPORT; NONHUMAN; PRIORITY JOURNAL; SYNAPSE;

ANIMALS; AXONAL TRANSPORT; AXONS; CYTOPLASM; DYNEIN ATPASE; MACROMOLECULAR SUBSTANCES; MICROTUBULES; MODELS, NEUROLOGICAL; MOLECULAR MOTOR PROTEINS; NEUROFILAMENT PROTEINS; PROTEIN SUBUNITS;

EID: 0034433637     PISSN: 03004864     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010995408343     Document Type: Article

References (77)

1. Microtubules and axonal growth
2. A composite model for establishing the microtubule arrays of the neuron
3. Interaction of the CD5 cytoplasmic domain with the Ca2+/calmodulin-dependent kinase IIdelta
4. Drosophila roadblock and Chlamydomonas LC7: A conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis
5. Neurofilaments run sprints not marathons
6. Biochemical and functional diversity of microtubule motors in the nervous system
7. I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain
8. Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome
9. Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport
10. Cytoplasmic dynein is associated with slow axonal transport
11. Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles
12. Pericentrin, a highly conserved centrosome protein involved in microtubule organization
13. Dynein light chain binding to a 3′-untranslated sequence mediates parathyroid hormone mRNA association with microtubules
14. An extended microtubule-binding structure within the dynein motor domain
15. Cytoplasmic dynein function is essential in Drosophila melanogaster
16. Characterization of DLC-A and DLC-B, two families of cytoplasmic dynein light chain subunits
17. Intracellular transport in neurons
18. A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA
19. Interaction mapping of a dynein heavy chain. Identification of dimerization and intermediate-chain binding domains
20. Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein
21. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
22. The mechanisms of fast and slow transport in neurons: Identification and characterization of the new kinesin superfamily motors
23. Kinesin and dynein superfamily proteins in organelle transport and cell division
24. Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo
25. Cellular and viral protein interactions regulating I kappa B alpha activity during human retrovirus infection
26. The role of the dynactin complex in intracellular motility
27. Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases
28. PIN: An associated protein inhibitor of neuronal nitric oxide synthase
29. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
30. A kinesin family tree
31. AAA domains and organization of the dynein motor unit
32. The dynein microtubule motor
33. Cytoplasmic dynein contains a family of differentially expressed light chains
34. Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain
35. The mouse t-complex-encoded protein Tctex-1 is a light chain of brain cytoplasmic dynein
36. The Mr 78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with alpha-tubulin in situ
37. Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy
38. Polymer sliding in axons
39. Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP
40. Cytoplasmic dynein conversion at a crush injury in rat peripheral axons
41. An adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis complexes with dynein and a small GTPase
42. Male sterility of the mouse t-complex is due to homozygosity of the distorter genes
43. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
44. Identification of a dynein molecular motor component in Torpedo electroplax; binding and phosphorylation of Tctex-1 by Fyn
45. Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport
46. Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein
47. The slow axonal transport debate
48. Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing
49. Isolated flagellar outer arm dynein translocates brain microtubules in vitro
50. Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function
51. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly
52. Cytoplasmic dynein and microtubule transport in the axon: The action connection
53. Identification and developmental regulation of a neuron-specific subunit of cytoplasmic dynein
54. Differential expression and phosphorylation of the 74-kDa intermediate chains of cytoplasmic dynein in cultured neurons and glia
55. Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas
56. Fast transport of neurofilament protein along microtubules in squid axoplasm
57. Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization
58. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
59. Signalling events regulating the retrograde axonal transport of 125I-beta nerve growth factor in vivo
60. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons
61. Neurofilaments are transported rapidly but intermittently in axons: Implications for slow axonal transport
62. Ultrastructural analysis of the dynactin complex: An actin-related protein is a component of a filament that resembles F-actin
63. Dynein is the motor for retrograde axonal transport of organelles
64. The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes
65. Bidirectional translocation of neurofilaments along microtubules mediated in part by Dynein/Dynactin
66. Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans
67. Immunogold localisation of the intermediate chain within the protein complex of cytoplasmic dynein
68. The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes
69. Distinct cytoplasmic dynein complexes are transported by different mechanisms in axons
70. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
71. Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain binding
72. Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin
73. The role of dynein in retrograde axonal transport
74. Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued
75. Rapid movement of axonal neurofilaments interrupted by prolonged pauses
76. The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)
77. The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport