메뉴 건너뛰기




Volumn 29, Issue 49, 2010, Pages 6452-6463

Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion

Author keywords

adhesion; breast cancer; integrin; invasion; MDGI; migration

Indexed keywords

ALPHA INTEGRIN; COLLAGEN TYPE 1; CYTOPLASM PROTEIN; FIBRONECTIN; HETERODIMER; MAMMARY DERIVED GROWTH INHIBITOR; UNCLASSIFIED DRUG;

EID: 78650018068     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.376     Document Type: Article
Times cited : (45)

References (47)
  • 1
    • 70450222316 scopus 로고    scopus 로고
    • The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
    • Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED et al. (2009). The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J28: 3623-3632.
    • (2009) EMBO J , vol.28 , pp. 3623-3632
    • Anthis, N.J.1    Wegener, K.L.2    Ye, F.3    Kim, C.4    Goult, B.T.5    Lowe, E.D.6
  • 2
    • 0028858576 scopus 로고
    • Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium
    • Bazzoni G, Shih DT, Buck CA, Hemler ME. (1995). Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium. J Biol Chem 270: 25570-25577.
    • (1995) J Biol Chem , vol.270 , pp. 25570-25577
    • Bazzoni, G.1    Shih, D.T.2    Buck, C.A.3    Hemler, M.E.4
  • 3
    • 44449148944 scopus 로고    scopus 로고
    • The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins
    • Bouaouina M, Lad Y, Calderwood DA. (2008). The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins. J Biol Chem 283: 6118-6125.
    • (2008) J Biol Chem , vol.283 , pp. 6118-6125
    • Bouaouina, M.1    Lad, Y.2    Calderwood, D.A.3
  • 5
    • 65449175981 scopus 로고    scopus 로고
    • SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin
    • Brandt DT, Baarlink C, Kitzing TM, Kremmer E, Ivaska J, Nollau P et al. (2009). SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin. Nat Cell Biol 11: 557-568.
    • (2009) Nat Cell Biol , vol.11 , pp. 557-568
    • Brandt, D.T.1    Baarlink, C.2    Kitzing, T.M.3    Kremmer, E.4    Ivaska, J.5    Nollau, P.6
  • 7
    • 70349309642 scopus 로고    scopus 로고
    • How ILK and kindlins cooperate to orchestrate integrin signaling
    • Bottcher RT, Lange A, Fassler R. (2009). How ILK and kindlins cooperate to orchestrate integrin signaling. Curr Opin Cell Biol 21: 670-675.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 670-675
    • Bottcher, R.T.1    Lange, A.2    Fassler, R.3
  • 8
    • 0034514074 scopus 로고    scopus 로고
    • Deletion of the gene encoding H-FABP/MDGI has no overt effects in the mammary gland
    • Clark AJ, Neil C, Gusterson B, McWhir J, Binas B. (2000). Deletion of the gene encoding H-FABP/MDGI has no overt effects in the mammary gland. Transgenic Res 9: 439-444.
    • (2000) Transgenic Res , vol.9 , pp. 439-444
    • Clark, A.J.1    Neil, C.2    Gusterson, B.3    McWhir, J.4    Binas, B.5
  • 10
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
    • Gietz RD, Woods RA. (2002). Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol 350: 87-96.
    • (2002) Methods Enzymol , vol.350 , pp. 87-96
    • Gietz, R.D.1    Woods, R.A.2
  • 11
    • 66449119343 scopus 로고    scopus 로고
    • Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects
    • Harburger DS, Bouaouina M, Calderwood DA. (2009). Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem 284: 11485-11497.
    • (2009) J Biol Chem , vol.284 , pp. 11485-11497
    • Harburger, D.S.1    Bouaouina, M.2    Calderwood, D.A.3
  • 12
    • 0043253165 scopus 로고    scopus 로고
    • The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function
    • Hertzel AV, Bernlohr DA. (2000). The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol Metab 11: 175-180.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 175-180
    • Hertzel, A.V.1    Bernlohr, D.A.2
  • 14
    • 0029960684 scopus 로고    scopus 로고
    • Silencing of the mammary-derived growth inhibitor (MDGI) gene in breast neoplasms is associated with epigenetic changes
    • Huynh H, Alpert L, Pollak M. (1996). Silencing of the mammary-derived growth inhibitor (MDGI) gene in breast neoplasms is associated with epigenetic changes. Cancer Res 56: 4865-4870.
    • (1996) Cancer Res , vol.56 , pp. 4865-4870
    • Huynh, H.1    Alpert, L.2    Pollak, M.3
  • 15
    • 0030659408 scopus 로고    scopus 로고
    • Stabilization of mammary-derived growth inhibitor messenger RNA by antiestrogens
    • Huynh H, Pollak M. (1997). Stabilization of mammary-derived growth inhibitor messenger RNA by antiestrogens. Clin Cancer Res 3: 2151-2156.
    • (1997) Clin Cancer Res , vol.3 , pp. 2151-2156
    • Huynh, H.1    Pollak, M.2
  • 16
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO. (2002). Integrins: bidirectional, allosteric signaling machines. Cell 110: 673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 17
    • 34848917292 scopus 로고    scopus 로고
    • In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method
    • Jarvius M, Paulsson J, Weibrecht I, Leuchowius KJ, Andersson AC, Wahlby C et al. (2007). In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method. Mol Cell Proteomics 6: 1500-1509.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1500-1509
    • Jarvius, M.1    Paulsson, J.2    Weibrecht, I.3    Leuchowius, K.J.4    Andersson, A.C.5    Wahlby, C.6
  • 18
    • 0034745356 scopus 로고    scopus 로고
    • Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration
    • Kiosses WB, Shattil SJ, Pampori N, Schwartz MA. (2001). Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration. Nat Cell Biol 3: 316-320.
    • (2001) Nat Cell Biol , vol.3 , pp. 316-320
    • Kiosses, W.B.1    Shattil, S.J.2    Pampori, N.3    Schwartz, M.A.4
  • 19
    • 1342346591 scopus 로고    scopus 로고
    • The kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion
    • Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC. (2004). The kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. J Biol Chem 279: 6824-6833.
    • (2004) J Biol Chem , vol.279 , pp. 6824-6833
    • Kloeker, S.1    Major, M.B.2    Calderwood, D.A.3    Ginsberg, M.H.4    Jones, D.A.5    Beckerle, M.C.6
  • 20
    • 0032586993 scopus 로고    scopus 로고
    • Depletion of alphaV integrins from osteosarcoma cells by intracel-lular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis
    • Koistinen P, Pulli T, Uitto VJ, Nissinen L, Hyypi T, Heino J. (1999). Depletion of alphaV integrins from osteosarcoma cells by intracel-lular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis. Matrix Biol 18: 239-251.
    • (1999) Matrix Biol , vol.18 , pp. 239-251
    • Koistinen, P.1    Pulli, T.2    Uitto, V.J.3    Nissinen, L.4    Hyypi, T.5    Heino, J.6
  • 21
    • 0025302568 scopus 로고
    • Developmental regulation of mammary-derived growth inhibitor expression in bovine mammary tissue
    • Kurtz A, Vogel F, Funa K, Heldin CH, Grosse R. (1990). Developmental regulation of mammary-derived growth inhibitor expression in bovine mammary tissue. J Cell Biol 110: 1779-1789.
    • (1990) J Cell Biol , vol.110 , pp. 1779-1789
    • Kurtz, A.1    Vogel, F.2    Funa, K.3    Heldin, C.H.4    Grosse, R.5
  • 22
    • 65649127175 scopus 로고    scopus 로고
    • The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
    • Lau TL, Kim C, Ginsberg MH, Ulmer TS. (2009). The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling. EMBO J 28: 1351-1361.
    • (2009) EMBO J , vol.28 , pp. 1351-1361
    • Lau, T.L.1    Kim, C.2    Ginsberg, M.H.3    Ulmer, T.S.4
  • 23
    • 61449220945 scopus 로고    scopus 로고
    • Genetic and cell biological analysis of integrin outside-in signaling
    • Legate KR, Wickstrom SA, Fassler R. (2009). Genetic and cell biological analysis of integrin outside-in signaling. Genes Dev 23: 397-418.
    • (2009) Genes Dev , vol.23 , pp. 397-418
    • Legate, K.R.1    Wickstrom, S.A.2    Fassler, R.3
  • 25
    • 0035151327 scopus 로고    scopus 로고
    • Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: Results from a nationwide study
    • Lundin J, Lundin M, Holli K, Kataja V, Elomaa L, Pylkkanen L et al. (2001). Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: results from a nationwide study. J Clin Oncol 19: 28-36.
    • (2001) J Clin Oncol , vol.19 , pp. 28-36
    • Lundin, J.1    Lundin, M.2    Holli, K.3    Kataja, V.4    Elomaa, L.5    Pylkkanen, L.6
  • 26
    • 16644396938 scopus 로고    scopus 로고
    • A specific interface between integrin transmembrane helices and affinity for ligand
    • Luo BH, Springer TA, Takagi J. (2004). A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol 2: e153.
    • (2004) PLoS Biol , vol.2
    • Luo, B.H.1    Springer, T.A.2    Takagi, J.3
  • 27
    • 15844363687 scopus 로고    scopus 로고
    • Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain
    • Luque A, Gomez M, Puzon W, Takada Y, Sanchez-Madrid F, Cabanas C. (1996). Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain. J Biol Chem 271: 11067-11075.
    • (1996) J Biol Chem , vol.271 , pp. 11067-11075
    • Luque, A.1    Gomez, M.2    Puzon, W.3    Takada, Y.4    Sanchez-Madrid, F.5    Cabanas, C.6
  • 28
    • 0035281806 scopus 로고    scopus 로고
    • Spin-system heterogeneities indicate a selected-fit mechanism in fatty acid binding to heart-type fatty acid-binding protein (H-FABP)
    • Lucke C, Rademacher M, Zimmerman AW, van Moerkerk HT, Veerkamp JH, Ruterjans H. (2001). Spin-system heterogeneities indicate a selected-fit mechanism in fatty acid binding to heart-type fatty acid-binding protein (H-FABP). Biochem J 354: 259-266.
    • (2001) Biochem J , vol.354 , pp. 259-266
    • Lucke, C.1    Rademacher, M.2    Zimmerman, A.W.3    Van Moerkerk, H.T.4    Veerkamp, J.H.5    Ruterjans, H.6
  • 29
    • 12344285901 scopus 로고    scopus 로고
    • Negative regulation of EGFR signalling through integrin-alpha1beta1- mediated activation of protein tyrosine phosphatase TCPTP
    • Mattila E, Pellinen T, Nevo J, Vuoriluoto K, Arjonen A, Ivaska J. (2005). Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP. Nat Cell Biol 7: 78-85.
    • (2005) Nat Cell Biol , vol.7 , pp. 78-85
    • Mattila, E.1    Pellinen, T.2    Nevo, J.3    Vuoriluoto, K.4    Arjonen, A.5    Ivaska, J.6
  • 30
    • 38749147215 scopus 로고    scopus 로고
    • Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity
    • Millon-Fremillon A, Bouvard D, Grichine A, Manet-Dupe S, Block MR, Albiges-Rizo C. (2008). Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity. J Cell Biol 180: 427-441.
    • (2008) J Cell Biol , vol.180 , pp. 427-441
    • Millon-Fremillon, A.1    Bouvard, D.2    Grichine, A.3    Manet-Dupe, S.4    Block, M.R.5    Albiges-Rizo, C.6
  • 31
    • 70350743119 scopus 로고    scopus 로고
    • Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance
    • Nevo J, Mattila E, Pellinen T, Yamamoto DL, Sara H, Iljin K et al. (2009). Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance. Clin Cancer Res 15: 6570-6581.
    • (2009) Clin Cancer Res , vol.15 , pp. 6570-6581
    • Nevo, J.1    Mattila, E.2    Pellinen, T.3    Yamamoto, D.L.4    Sara, H.5    Iljin, K.6
  • 32
    • 33747447033 scopus 로고    scopus 로고
    • Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins
    • Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J. (2006). Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins. J Cell Biol 173: 767-780.
    • (2006) J Cell Biol , vol.173 , pp. 767-780
    • Pellinen, T.1    Arjonen, A.2    Vuoriluoto, K.3    Kallio, K.4    Fransen, J.A.5    Ivaska, J.6
  • 33
    • 0026738947 scopus 로고
    • Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
    • Petersen OW, Ronnov-Jessen L, Howlett AR, Bissell MJ. (1992). Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci USA 89: 9064-9068.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9064-9068
    • Petersen, O.W.1    Ronnov-Jessen, L.2    Howlett, A.R.3    Bissell, M.J.4
  • 34
    • 34547120497 scopus 로고    scopus 로고
    • The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility
    • Shi X, Ma YQ, Tu Y, Chen K, Wu S, Fukuda K et al. (2007). The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility. J Biol Chem 282: 20455-20466.
    • (2007) J Biol Chem , vol.282 , pp. 20455-20466
    • Shi, X.1    Ma, Y.Q.2    Tu, Y.3    Chen, K.4    Wu, S.5    Fukuda, K.6
  • 36
    • 0141865705 scopus 로고    scopus 로고
    • Talin binding to integrin beta tails: A final common step in integrin activation
    • Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM et al. (2003). Talin binding to integrin beta tails: a final common step in integrin activation. Science 302: 103-106.
    • (2003) Science , vol.302 , pp. 103-106
    • Tadokoro, S.1    Shattil, S.J.2    Eto, K.3    Tai, V.4    Liddington, R.C.5    De Pereda, J.M.6
  • 37
    • 52649141494 scopus 로고    scopus 로고
    • Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding
    • Takala H, Nurminen E, Nurmi SM, Aatonen M, Strandin T, Takatalo M et al. (2008). Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding. Blood 112: 1853-1862.
    • (2008) Blood , vol.112 , pp. 1853-1862
    • Takala, H.1    Nurminen, E.2    Nurmi, S.M.3    Aatonen, M.4    Strandin, T.5    Takatalo, M.6
  • 38
    • 69849101598 scopus 로고    scopus 로고
    • PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells
    • Tuomi S, Mai A, Nevo J, Laine JO, Vilkki V, hman TJ et al. (2009). PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells. Sci Signal 2: ra32.
    • (2009) Sci Signal , vol.2
    • Tuomi, S.1    Mai, A.2    Nevo, J.3    Laine, J.O.4    Vilkki, V.5    Hman, T.J.6
  • 39
    • 0037009820 scopus 로고    scopus 로고
    • Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
    • Wang F, Hansen RK, Radisky D, Yoneda T, Barcellos-Hoff MH, Petersen OW et al. (2002). Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst 94: 1494-1503.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1494-1503
    • Wang, F.1    Hansen, R.K.2    Radisky, D.3    Yoneda, T.4    Barcellos-Hoff, M.H.5    Petersen, O.W.6
  • 40
    • 0034636457 scopus 로고    scopus 로고
    • Breast cancer growth inhibition by delivery of the MDGI-derived peptide P108
    • Wang HL, Kurtz A. (2000). Breast cancer growth inhibition by delivery of the MDGI-derived peptide P108. Oncogene 19: 2455-2460.
    • (2000) Oncogene , vol.19 , pp. 2455-2460
    • Wang, H.L.1    Kurtz, A.2
  • 41
    • 9244222742 scopus 로고    scopus 로고
    • Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
    • Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E et al. (2004). Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 64: 8585-8594.
    • (2004) Cancer Res , vol.64 , pp. 8585-8594
    • Wang, W.1    Goswami, S.2    Lapidus, K.3    Wells, A.L.4    Wyckoff, J.B.5    Sahai, E.6
  • 42
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C et al. (1997). Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137: 231-245.
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6
  • 44
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • White DE, Kurpios NA, Zuo D, Hassell JA, Blaess S, Mueller U et al. (2004). Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6: 159-170.
    • (2004) Cancer Cell , vol.6 , pp. 159-170
    • White, D.E.1    Kurpios, N.A.2    Zuo, D.3    Hassell, J.A.4    Blaess, S.5    Mueller, U.6
  • 45
    • 1642529548 scopus 로고    scopus 로고
    • Membrane-mediated structural transitions at the cytoplas-mic face during integrin activation
    • Vinogradova O, Vaynberg J, Kong X, Haas TA, Plow EF, Qin J. (2004). Membrane-mediated structural transitions at the cytoplas-mic face during integrin activation. Proc Natl Acad Sci USA 101: 4094-4099.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4094-4099
    • Vinogradova, O.1    Vaynberg, J.2    Kong, X.3    Haas, T.A.4    Plow, E.F.5    Qin, J.6
  • 46
    • 33846653542 scopus 로고    scopus 로고
    • Increased beta1 integrin is associated with decreased survival in invasive breast cancer
    • Yao ES, Zhang H, Chen YY, Lee B, Chew K, Moore D et al. (2007). Increased beta1 integrin is associated with decreased survival in invasive breast cancer. Cancer Res 67: 659-664.
    • (2007) Cancer Res , vol.67 , pp. 659-664
    • Yao, E.S.1    Zhang, H.2    Chen, Y.Y.3    Lee, B.4    Chew, K.5    Moore, D.6
  • 47
    • 51049100594 scopus 로고    scopus 로고
    • Talin depletion reveals independence of initial cell spreading from integrin activation and traction
    • Zhang X, Jiang G, Cai Y, Monkley SJ, Critchley DR, Sheetz MP. (2008). Talin depletion reveals independence of initial cell spreading from integrin activation and traction. Nat Cell Biol 10: 1062-1068.
    • (2008) Nat Cell Biol , vol.10 , pp. 1062-1068
    • Zhang, X.1    Jiang, G.2    Cai, Y.3    Monkley, S.J.4    Critchley, D.R.5    Sheetz, M.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.