-
1
-
-
44249086425
-
Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
-
J.R. Molina, P. Yang, S.D. Cassivi, S.E. Schild, and A.A. Adjei Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship Mayo Clin Proc 83 2008 584 594
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 584-594
-
-
Molina, J.R.1
Yang, P.2
Cassivi, S.D.3
Schild, S.E.4
Adjei, A.A.5
-
2
-
-
0041891741
-
Clinical implications of p53 mutations in lung cancer
-
B.G. Campling, and W.S. el-Deiry Clinical implications of p53 mutations in lung cancer Methods Mol Med 75 2003 53 77
-
(2003)
Methods Mol Med
, vol.75
, pp. 53-77
-
-
Campling, B.G.1
El-Deiry, W.S.2
-
3
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
J. Li, C. Yen, and D. Liaw PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer Science 275 1997 1943 1947
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
4
-
-
0032581519
-
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers
-
A. Yokomizo, D.J. Tindall, and H. Drabkin PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers Oncogene 17 1998 475 479
-
(1998)
Oncogene
, vol.17
, pp. 475-479
-
-
Yokomizo, A.1
Tindall, D.J.2
Drabkin, H.3
-
5
-
-
0036094196
-
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
-
J.C. Soria, H.Y. Lee, and J.I. Lee Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation Clin Cancer Res 8 2002 1178 1184
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1178-1184
-
-
Soria, J.C.1
Lee, H.Y.2
Lee, J.I.3
-
6
-
-
0032806874
-
Alteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis
-
Y. Hosoya, A. Gemma, and M. Seike Alteration of the PTEN/MMAC1 gene locus in primary lung cancer with distant metastasis Lung Cancer 25 1999 87 93
-
(1999)
Lung Cancer
, vol.25
, pp. 87-93
-
-
Hosoya, Y.1
Gemma, A.2
Seike, M.3
-
8
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
V. Stambolic, D. MacPherson, and D. Sas Regulation of PTEN transcription by p53 Mol Cell 8 2001 317 325
-
(2001)
Mol Cell
, vol.8
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
-
9
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and independent mechanisms
-
D.J. Freeman, A.G. Li, and G. Wei PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and independent mechanisms Cancer Cell 3 2003 117 130
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, G.3
-
10
-
-
40949097860
-
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations
-
Y. Li, F. Guessous, and S. Kwon PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations Cancer Res 68 2008 1723 1731
-
(2008)
Cancer Res
, vol.68
, pp. 1723-1731
-
-
Li, Y.1
Guessous, F.2
Kwon, S.3
-
11
-
-
33846160505
-
Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA
-
J.S. Kim, C. Lee, C.L. Bonifant, H. Ressom, and T. Waldman Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA Mol Cell Biol 27 2007 662 677
-
(2007)
Mol Cell Biol
, vol.27
, pp. 662-677
-
-
Kim, J.S.1
Lee, C.2
Bonifant, C.L.3
Ressom, H.4
Waldman, T.5
-
12
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Z. Chen, L.C. Trotman, and D. Shaffer Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis Nature 436 2005 725 730
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
-
13
-
-
16244371591
-
-
IARC Press Lyon, France
-
W.D. Travis, E. Brambilla, H.K. Müller-Hermelink, C.C. Harris, WHO classification of tumors. Pathology and genetics of tumors of the lung, pleura, thymus and heart 2004 IARC Press Lyon, France
-
(2004)
WHO Classification of Tumors. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart
-
-
Travis, W.D.1
Brambilla, E.2
Müller-Hermelink, H.K.3
Harris, C.C.4
-
14
-
-
72549094017
-
Identification of genes associated with non-small-cell lung cancer promotion and progression
-
J. Bankovic, J. Stojsic, and D. Jovanovic Identification of genes associated with non-small-cell lung cancer promotion and progression Lung Cancer 67 2010 151 159
-
(2010)
Lung Cancer
, vol.67
, pp. 151-159
-
-
Bankovic, J.1
Stojsic, J.2
Jovanovic, D.3
-
16
-
-
40149084500
-
Genomic instability in patients with non-small cell lung cancer assessed by the arbitrarily primed polymerase chain reaction
-
J. Markovic, J. Stojsic, S. Zunic, S. Ruzdijic, and N. Tanic Genomic instability in patients with non-small cell lung cancer assessed by the arbitrarily primed polymerase chain reaction Cancer Invest 26 2008 262 268
-
(2008)
Cancer Invest
, vol.26
, pp. 262-268
-
-
Markovic, J.1
Stojsic, J.2
Zunic, S.3
Ruzdijic, S.4
Tanic, N.5
-
17
-
-
0024595101
-
Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
-
M. Orita, H. Iwahana, H. Kanazawa, K. Hayashi, and T. Sekiya Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms Proc Natl Acad Sci U S A 86 1989 2766 2770
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 2766-2770
-
-
Orita, M.1
Iwahana, H.2
Kanazawa, H.3
Hayashi, K.4
Sekiya, T.5
-
18
-
-
47949104284
-
Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)
-
T. Andjelkovic, M. Pesic, J. Bankovic, N. Tanic, I.D. Markovic, and S. Ruzdijic Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R) Cancer Biol Ther 7 2008 1024 1032
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1024-1032
-
-
Andjelkovic, T.1
Pesic, M.2
Bankovic, J.3
Tanic, N.4
Markovic, I.D.5
Ruzdijic, S.6
-
19
-
-
0032473921
-
Analysis of PTEN and the 10q23 region in primary prostate carcinomas
-
H.E. Feilotter, M.A. Nagai, A.H. Boag, C. Eng, and L.M. Mulligan Analysis of PTEN and the 10q23 region in primary prostate carcinomas Oncogene 16 1998 1743 1748
-
(1998)
Oncogene
, vol.16
, pp. 1743-1748
-
-
Feilotter, H.E.1
Nagai, M.A.2
Boag, A.H.3
Eng, C.4
Mulligan, L.M.5
-
20
-
-
0032835341
-
Genetic Alterations of the Tumor Suppressor Gene PTEN/MMAC1 in Human Brain Metastases
-
M. Hahn, I. Wieland, and O.N. Koufaki Genetic Alterations of the Tumor Suppressor Gene PTEN/MMAC1 in Human Brain Metastases Clin Cancer Res 5 1999 2431 2437
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2431-2437
-
-
Hahn, M.1
Wieland, I.2
Koufaki, O.N.3
-
21
-
-
0033572286
-
Clonal expansion, and loss of heterozygosity at chromosomes 9p, and 17p in premalignant esophageal (Barrett's) tissue
-
P.C. Galipeau, L.J. Prevo, C.A. Sanchez, G.M. Longton, and B.J. Reid Clonal expansion, and loss of heterozygosity at chromosomes 9p, and 17p in premalignant esophageal (Barrett's) tissue J Nat Cancer Inst 91 1999 2087 2095
-
(1999)
J Nat Cancer Inst
, vol.91
, pp. 2087-2095
-
-
Galipeau, P.C.1
Prevo, L.J.2
Sanchez, C.A.3
Longton, G.M.4
Reid, B.J.5
-
22
-
-
0034793846
-
Predictors of progression in Barrett's esophagus II: Baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression
-
B.J. Reid, L.J. Prevo, and P.C. Galipeau Predictors of progression in Barrett's esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression Am J Gastroenterol 96 2001 2839 2848
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2839-2848
-
-
Reid, B.J.1
Prevo, L.J.2
Galipeau, P.C.3
-
23
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
J.G. Herman, J.R. Graff, S. Myöhänen, B.D. Nelkin, and S.B. Baylin Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands Proc Natl Acad Sci U S A 93 1996 9821 9826
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myöhänen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
24
-
-
0036121266
-
Considerations when analyzing the methylation status of PTEN tumor suppressor gene
-
M.A. Zysman, W.B. Chapman, and B. Bapat Considerations when analyzing the methylation status of PTEN tumor suppressor gene Am J Pathol 160 2002 795 800
-
(2002)
Am J Pathol
, vol.160
, pp. 795-800
-
-
Zysman, M.A.1
Chapman, W.B.2
Bapat, B.3
-
25
-
-
0025783775
-
Polymorphism at codon 213 within the p53 gene
-
D. Carbone, I. Chiba, and T. Mitsudomi Polymorphism at codon 213 within the p53 gene Oncogene 6 1991 1691 1692
-
(1991)
Oncogene
, vol.6
, pp. 1691-1692
-
-
Carbone, D.1
Chiba, I.2
Mitsudomi, T.3
-
26
-
-
0036843937
-
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
-
K. Kurose, K. Gilley, S. Matsumoto, P.H. Watson, X.P. Zhou, and C. Eng Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas Nat Genet 32 2002 355 357
-
(2002)
Nat Genet
, vol.32
, pp. 355-357
-
-
Kurose, K.1
Gilley, K.2
Matsumoto, S.3
Watson, P.H.4
Zhou, X.P.5
Eng, C.6
-
27
-
-
55549090038
-
Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
-
S.A. Danielsen, G.E. Lind, and M. Bjørnslett Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status Hum Mutat 29 2008 E252 E262
-
(2008)
Hum Mutat
, vol.29
-
-
Danielsen, S.A.1
Lind, G.E.2
Bjørnslett, M.3
-
28
-
-
0344407448
-
Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma
-
T.H. Hu, C.C. Huang, and P.R. Lin Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma Cancer 97 2003 1929 1940
-
(2003)
Cancer
, vol.97
, pp. 1929-1940
-
-
Hu, T.H.1
Huang, C.C.2
Lin, P.R.3
-
29
-
-
22744452500
-
Genetic mutual relationship between PTEN and p53 in gastric cancer
-
E. Oki, E. Tokunaga, and T. Nakamura Genetic mutual relationship between PTEN and p53 in gastric cancer Cancer Lett 227 2005 33 38
-
(2005)
Cancer Lett
, vol.227
, pp. 33-38
-
-
Oki, E.1
Tokunaga, E.2
Nakamura, T.3
-
30
-
-
0035150974
-
Loss of heterozygosity is related to p53 mutations and smoking in lung cancer
-
S. Zienolddiny, D. Ryberg, M.O. Arab, V. Skaug, and A. Haugen Loss of heterozygosity is related to p53 mutations and smoking in lung cancer Br J Cancer 84 2001 226 231
-
(2001)
Br J Cancer
, vol.84
, pp. 226-231
-
-
Zienolddiny, S.1
Ryberg, D.2
Arab, M.O.3
Skaug, V.4
Haugen, A.5
-
31
-
-
31344479312
-
Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis
-
J.M. Tang, Q.Y. He, R.X. Guo, and X.J. Chang Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis Lung Cancer 51 2006 181 191
-
(2006)
Lung Cancer
, vol.51
, pp. 181-191
-
-
Tang, J.M.1
He, Q.Y.2
Guo, R.X.3
Chang, X.J.4
-
32
-
-
0031205544
-
Association between p53 mutation and clinicopathological features of non-small cell lung cancer
-
S.G. Guang, T. Ogura, and I. Sekine Association between p53 mutation and clinicopathological features of non-small cell lung cancer Jpn J Clin Oncol 27 1997 211 215
-
(1997)
Jpn J Clin Oncol
, vol.27
, pp. 211-215
-
-
Guang, S.G.1
Ogura, T.2
Sekine, I.3
-
33
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
M. Tamura, J. Gu, K. Matsumoto, S. Aota, R. Parsons, and K.M. Yamada Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN Science 280 1998 1614 1617
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
34
-
-
77956626576
-
Focal adhesion kinase and p53 signal transduction pathways in cancer
-
V.M. Golubovskaya, and W. Cance Focal adhesion kinase and p53 signal transduction pathways in cancer Front Biosci 15 2010 901 912
-
(2010)
Front Biosci
, vol.15
, pp. 901-912
-
-
Golubovskaya, V.M.1
Cance, W.2
-
35
-
-
0343183328
-
Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
-
J. Liliental, S.Y. Moon, and R. Lesche Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases Curr Biol 10 2000 401 404
-
(2000)
Curr Biol
, vol.10
, pp. 401-404
-
-
Liliental, J.1
Moon, S.Y.2
Lesche, R.3
-
36
-
-
0037093470
-
Regulation of Cdc42-mediated morphological effects: A novel function for p53
-
G. Gadéa, L. Lapasset, C. Gauthier-Rouvire, and P. Roux Regulation of Cdc42-mediated morphological effects: a novel function for p53 EMBO J 21 2002 2373 2382
-
(2002)
EMBO J
, vol.21
, pp. 2373-2382
-
-
Gadéa, G.1
Lapasset, L.2
Gauthier-Rouvire, C.3
Roux, P.4
-
37
-
-
0035196043
-
PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
-
H.B. Salvesen, N. MacDonald, and A. Ryan PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma Int J Cancer 91 2001 22 26
-
(2001)
Int J Cancer
, vol.91
, pp. 22-26
-
-
Salvesen, H.B.1
MacDonald, N.2
Ryan, A.3
-
38
-
-
2342504508
-
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
-
A. Goel, C.N. Arnold, and D. Niedzwiecki Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers Cancer Res 64 2004 3014 3021
-
(2004)
Cancer Res
, vol.64
, pp. 3014-3021
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
-
39
-
-
51849086880
-
PTEN: A new guardian of the genome
-
Y. Yin, and W.H. Shen PTEN: a new guardian of the genome Oncogene 27 2008 5443 5453
-
(2008)
Oncogene
, vol.27
, pp. 5443-5453
-
-
Yin, Y.1
Shen, W.H.2
-
40
-
-
33646814435
-
Double Bolt Regulation of Rad51 by p53
-
I. Lazaro-Trueba, C. Arias, and A. Silva Double Bolt Regulation of Rad51 by p53 Cell Cycle 5 2006 1062 1065
-
(2006)
Cell Cycle
, vol.5
, pp. 1062-1065
-
-
Lazaro-Trueba, I.1
Arias, C.2
Silva, A.3
-
41
-
-
0034011427
-
Significance of multiple mutations in cancer
-
K.R. Loeb, and L.A. Loeb Significance of multiple mutations in cancer Carcinogenesis 21 2000 379 385
-
(2000)
Carcinogenesis
, vol.21
, pp. 379-385
-
-
Loeb, K.R.1
Loeb, L.A.2
-
42
-
-
63049094489
-
Inactivation of p53 and Pten promotes invasive bladder cancer
-
A.M. Puzio-Kuter, M. Castillo-Martin, and C.W. Kinkade Inactivation of p53 and Pten promotes invasive bladder cancer Genes Dev 23 2009 675 680
-
(2009)
Genes Dev
, vol.23
, pp. 675-680
-
-
Puzio-Kuter, A.M.1
Castillo-Martin, M.2
Kinkade, C.W.3
-
43
-
-
63949083916
-
Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis
-
L. Catasus, A. Gallardo, M. Cuatrecasas, and J. Prat Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis Mod Pathol 22 2009 522 529
-
(2009)
Mod Pathol
, vol.22
, pp. 522-529
-
-
Catasus, L.1
Gallardo, A.2
Cuatrecasas, M.3
Prat, J.4
-
44
-
-
1542674341
-
Correlation of molecular genetic analysis of P53, MDM2, P16, PTEN, and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma
-
Y. Ushio, K. Tada, and S. Shiraishi Correlation of molecular genetic analysis of P53, MDM2, P16, PTEN, and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma Front Biosci 8 2003 e281 e288
-
(2003)
Front Biosci
, vol.8
-
-
Ushio, Y.1
Tada, K.2
Shiraishi, S.3
-
45
-
-
70349678707
-
Increased tissue factor expression is associated with reduced survival in non-small cell lung cancer and with mutations of TP53 and PTEN
-
S. Regina, J.B. Valentin, and S. Lachot Increased tissue factor expression is associated with reduced survival in non-small cell lung cancer and with mutations of TP53 and PTEN Clin Chem 55 2009 1834 1842
-
(2009)
Clin Chem
, vol.55
, pp. 1834-1842
-
-
Regina, S.1
Valentin, J.B.2
Lachot, S.3
|