메뉴 건너뛰기




Volumn 7, Issue 7, 2008, Pages 1024-1032

Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)

Author keywords

Curcumin; Drug combination; Gene expression; Lung carcinoma; Multidrug resistance; p53 status; Sulfinosine

Indexed keywords

CURCUMIN; SULFINOSINE;

EID: 47949104284     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.7.6036     Document Type: Article
Times cited : (57)

References (54)
  • 2
    • 0027474456 scopus 로고
    • How cancer cells evade chemotherapy: Sixteenth Richard and Hinda Rosenthal Foundation Award Lecture
    • Gottesman MM. How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res 1993; 53:747-54.
    • (1993) Cancer Res , vol.53 , pp. 747-754
    • Gottesman, M.M.1
  • 3
    • 0033628853 scopus 로고    scopus 로고
    • Cellular mechanisms of multidrug resistance of tumor cells
    • Stavrovskaya AA. Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry (Mosc) 2000; 65:95-106.
    • (2000) Biochemistry (Mosc) , vol.65 , pp. 95-106
    • Stavrovskaya, A.A.1
  • 5
    • 0037037822 scopus 로고    scopus 로고
    • The p53 network in lung carcinogenesis
    • Robles AI, Linke SP, Harris CC. The p53 network in lung carcinogenesis. Oncogene 2002; 21:6898-907.
    • (2002) Oncogene , vol.21 , pp. 6898-6907
    • Robles, A.I.1    Linke, S.P.2    Harris, C.C.3
  • 6
    • 3242803674 scopus 로고    scopus 로고
    • Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis
    • Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis. JAMA 2004; 292:470-84.
    • (2004) JAMA , vol.292 , pp. 470-484
    • Delbaldo, C.1    Michiels, S.2    Syz, N.3    Soria, J.C.4    Le Chevalier, T.5    Pignon, J.P.6
  • 7
    • 0025056721 scopus 로고
    • Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6- sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides
    • Revankar GR, Hanna NB, Imamura N, Lewis AF, Larson SB, Finch RA, Avery TL, Robins RK. Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6- sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides. J Med Chem 1990; 33:121-8.
    • (1990) J Med Chem , vol.33 , pp. 121-128
    • Revankar, G.R.1    Hanna, N.B.2    Imamura, N.3    Lewis, A.F.4    Larson, S.B.5    Finch, R.A.6    Avery, T.L.7    Robins, R.K.8
  • 8
    • 0025278171 scopus 로고
    • Chemotherapeutic characterization in mice of 2-amino-9-beta-D- ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties
    • Avery TL, Finch RA, Vasquez KM, Radparvar S, Hanna NB, Revankar GR, Robins RK. Chemotherapeutic characterization in mice of 2-amino-9-beta-D- ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties. Cancer Res 1990; 50:2625-30.
    • (1990) Cancer Res , vol.50 , pp. 2625-2630
    • Avery, T.L.1    Finch, R.A.2    Vasquez, K.M.3    Radparvar, S.4    Hanna, N.B.5    Revankar, G.R.6    Robins, R.K.7
  • 10
    • 31644445018 scopus 로고    scopus 로고
    • The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro
    • Jankovic D, Pesic M, Markovic J, Kanazir S, Markovic I, Rakic L, Ruzdijic S. The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro. Invest New Drugs 2006; 24:15-25.
    • (2006) Invest New Drugs , vol.24 , pp. 15-25
    • Jankovic, D.1    Pesic, M.2    Markovic, J.3    Kanazir, S.4    Markovic, I.5    Rakic, L.6    Ruzdijic, S.7
  • 11
    • 47949088823 scopus 로고
    • Cellular metabolism of the antitumor nucleoside, sulfinosine, 2-amino-9-(β-D-ribofuranosyl)purine-6-sulfinamide
    • Fujitaki JM, Nord LD, Willis RC. Cellular metabolism of the antitumor nucleoside, sulfinosine, 2-amino-9-(β-D-ribofuranosyl)purine-6-sulfinamide. Proc Am Assoc Cancer Res 1989; 30:596.
    • (1989) Proc Am Assoc Cancer Res , vol.30 , pp. 596
    • Fujitaki, J.M.1    Nord, L.D.2    Willis, R.C.3
  • 12
    • 33645109974 scopus 로고    scopus 로고
    • Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs
    • Pesic M, Markovic JZ, Jankovic D, Kanazir S, Markovic ID, Rakic L, Ruzdijic S. Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs. J Chemother 2006; 18:66-73.
    • (2006) J Chemother , vol.18 , pp. 66-73
    • Pesic, M.1    Markovic, J.Z.2    Jankovic, D.3    Kanazir, S.4    Markovic, I.D.5    Rakic, L.6    Ruzdijic, S.7
  • 13
    • 5644283296 scopus 로고    scopus 로고
    • Role of chemopreventive agents in cancer therapy
    • Dorai T, Aggarwal BB. Role of chemopreventive agents in cancer therapy. Cancer Lett 2004; 215:129-40.
    • (2004) Cancer Lett , vol.215 , pp. 129-140
    • Dorai, T.1    Aggarwal, B.B.2
  • 14
    • 84934443974 scopus 로고    scopus 로고
    • Curcumin as chemosensitizer
    • Limtrakul P. Curcumin as chemosensitizer. Adv Exp Med Biol 2007; 595:269-300.
    • (2007) Adv Exp Med Biol , vol.595 , pp. 269-300
    • Limtrakul, P.1
  • 15
    • 0000163138 scopus 로고
    • Analysis and cloning of eucaryotic genomic DNA
    • Nolan C, ed, Second edition. New York: Cold Spring Harbor Laboratory Press, USA
    • Sambrook J, Fritsch EF, Maniatis T. Analysis and cloning of eucaryotic genomic DNA. In: Nolan C, ed. Molecular cloning: a laboratory manual. Second edition. New York: Cold Spring Harbor Laboratory Press, USA 1982; 16-19.
    • (1982) Molecular cloning: A laboratory manual , pp. 16-19
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 16
    • 0024595101 scopus 로고
    • Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
    • Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 1989; 86:2766-70.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2766-2770
    • Orita, M.1    Iwahana, H.2    Kanazawa, H.3    Hayashi, K.4    Sekiya, T.5
  • 19
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984; 22:27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 21
    • 2642690680 scopus 로고    scopus 로고
    • Correlation between multidrug resistance and the degree of differentiation of non-small-cell bronchopulmonary carcinoma (NSCLC) in vitro and in vivo
    • Bosch S, Siavoshian S, Jacquot C, Tomasoni C, Dabouis G, Elanbaloussi Y, Leneel T, More MT, Roussakis C. Correlation between multidrug resistance and the degree of differentiation of non-small-cell bronchopulmonary carcinoma (NSCLC) in vitro and in vivo. Anticancer Res 1997; 17:4595-8.
    • (1997) Anticancer Res , vol.17 , pp. 4595-4598
    • Bosch, S.1    Siavoshian, S.2    Jacquot, C.3    Tomasoni, C.4    Dabouis, G.5    Elanbaloussi, Y.6    Leneel, T.7    More, M.T.8    Roussakis, C.9
  • 22
    • 0027711809 scopus 로고
    • The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells
    • O'Driscoll L, Daly C, Saleh M, Clynes M. The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells. Cytotechnology 1993; 12:289-314.
    • (1993) Cytotechnology , vol.12 , pp. 289-314
    • O'Driscoll, L.1    Daly, C.2    Saleh, M.3    Clynes, M.4
  • 23
    • 0031304677 scopus 로고    scopus 로고
    • Evaluation of three rapid RNA extraction reagents: Relevance for use in RT-PCR's and measurement of low level gene expression in clinical samples
    • Chadderton T, Wilson C, Bewick M, Gluck S. Evaluation of three rapid RNA extraction reagents: relevance for use in RT-PCR's and measurement of low level gene expression in clinical samples. Cell Mol Biol (Noisy-le-grand) 1997; 43:1227-34.
    • (1997) Cell Mol Biol (Noisy-le-grand) , vol.43 , pp. 1227-1234
    • Chadderton, T.1    Wilson, C.2    Bewick, M.3    Gluck, S.4
  • 24
    • 0028151418 scopus 로고
    • Monitoring mRNA expression by polymerase chain reaction: The "primer-dropping" method
    • Wong H, Anderson WD, Cheng T, Riabowol KT. Monitoring mRNA expression by polymerase chain reaction: the "primer-dropping" method. Anal Biochem 1994; 223:251-8.
    • (1994) Anal Biochem , vol.223 , pp. 251-258
    • Wong, H.1    Anderson, W.D.2    Cheng, T.3    Riabowol, K.T.4
  • 25
    • 0021759199 scopus 로고
    • Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA
    • Ponte P, Ng SY, Engel J, Gunning P, Kedes L. Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res 1984; 12:1687-96.
    • (1984) Nucleic Acids Res , vol.12 , pp. 1687-1696
    • Ponte, P.1    Ng, S.Y.2    Engel, J.3    Gunning, P.4    Kedes, L.5
  • 28
    • 23844455227 scopus 로고    scopus 로고
    • Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR
    • Tang XQ, Bi H, Feng JQ, Cao JG. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Acta Pharmacol Sin 2005; 26:1009-16.
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 1009-1016
    • Tang, X.Q.1    Bi, H.2    Feng, J.Q.3    Cao, J.G.4
  • 29
    • 33745884111 scopus 로고    scopus 로고
    • Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II
    • Cantero G, Pastor N, Mateos S, Campanella C, Cortes F. Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II. Mutat Res 2006; 599:160-6.
    • (2006) Mutat Res , vol.599 , pp. 160-166
    • Cantero, G.1    Pastor, N.2    Mateos, S.3    Campanella, C.4    Cortes, F.5
  • 30
    • 0018852426 scopus 로고
    • 2 blocks and their significance to the mechanism of cytotoxicity
    • 2 blocks and their significance to the mechanism of cytotoxicity. Cancer Res 1980; 40:1458-62.
    • (1980) Cancer Res , vol.40 , pp. 1458-1462
    • Wotring, L.L.1    Roti Roti, J.L.2
  • 31
    • 37549050536 scopus 로고    scopus 로고
    • Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1)
    • Srivastava RK, Chen Q, Siddiqui I, Sarva K, Shankar S. Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1). Cell Cycle 2007; 6:2953-61.
    • (2007) Cell Cycle , vol.6 , pp. 2953-2961
    • Srivastava, R.K.1    Chen, Q.2    Siddiqui, I.3    Sarva, K.4    Shankar, S.5
  • 34
    • 0026622878 scopus 로고
    • Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-pi in human lung tumors
    • Volm M, Mattern J, Samsel B. Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-pi in human lung tumors. Cancer 1992; 70:764-9.
    • (1992) Cancer , vol.70 , pp. 764-769
    • Volm, M.1    Mattern, J.2    Samsel, B.3
  • 35
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDR1 gene by Ras and p53
    • Chin KV, Ueda K, Pastan I, Gottesman MM. Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science 1992; 255:459-62.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 36
    • 0035920197 scopus 로고    scopus 로고
    • Transcriptional repression by p53 through direct binding to a novel DNA element
    • Johnson RA, Ince TA, Scotto KW. Transcriptional repression by p53 through direct binding to a novel DNA element. J Biol Chem 2001; 276:27716-20.
    • (2001) J Biol Chem , vol.276 , pp. 27716-27720
    • Johnson, R.A.1    Ince, T.A.2    Scotto, K.W.3
  • 38
  • 40
    • 36849021582 scopus 로고    scopus 로고
    • Curcumin downregulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NFkappaB pathway
    • Choi BH, Kim CG, Lim Y, Shin SY, Lee YH. Curcumin downregulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NFkappaB pathway. Cancer Lett 2008; 259:111-8.
    • (2008) Cancer Lett , vol.259 , pp. 111-118
    • Choi, B.H.1    Kim, C.G.2    Lim, Y.3    Shin, S.Y.4    Lee, Y.H.5
  • 41
    • 0028106016 scopus 로고
    • Glutathione-associated enzymes in anticancer drug resistance
    • Tew KD. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res 1994; 54:4313-20.
    • (1994) Cancer Res , vol.54 , pp. 4313-4320
    • Tew, K.D.1
  • 44
    • 0026664058 scopus 로고
    • Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression
    • Giaccone G, Gazdar AF, Beck H, Zunino F, Capranico G. Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression. Cancer Res 1992; 52:1666-74.
    • (1992) Cancer Res , vol.52 , pp. 1666-1674
    • Giaccone, G.1    Gazdar, A.F.2    Beck, H.3    Zunino, F.4    Capranico, G.5
  • 46
    • 0031014797 scopus 로고    scopus 로고
    • Inhibition of DNA topoisomerase IIalpha gene expression by the p53 tumor suppressor
    • Wang Q, Zambetti GP, Suttle DP. Inhibition of DNA topoisomerase IIalpha gene expression by the p53 tumor suppressor. Mol Cell Biol 1997; 17:389-97.
    • (1997) Mol Cell Biol , vol.17 , pp. 389-397
    • Wang, Q.1    Zambetti, G.P.2    Suttle, D.P.3
  • 47
    • 0037089019 scopus 로고    scopus 로고
    • Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in nonsmall cell lung carcinoma patients
    • Liu D, Huang CL, Kameyama K, Hayashi E, Yamauchi A, Sumitomo S, Yokomise H. Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in nonsmall cell lung carcinoma patients. Cancer 2002; 94:2239-47.
    • (2002) Cancer , vol.94 , pp. 2239-2247
    • Liu, D.1    Huang, C.L.2    Kameyama, K.3    Hayashi, E.4    Yamauchi, A.5    Sumitomo, S.6    Yokomise, H.7
  • 49
    • 0034741578 scopus 로고    scopus 로고
    • DNA topoisomerase IIalpha in multiple myeloma. a marker of cell proliferation and not drug resistance
    • Wilson CS, Medeiros LJ, Lai R, Butch AW, McCourty A, Kelly K, Brynes RK. DNA topoisomerase IIalpha in multiple myeloma. a marker of cell proliferation and not drug resistance. Mod Pathol 2001; 14:886-91.
    • (2001) Mod Pathol , vol.14 , pp. 886-891
    • Wilson, C.S.1    Medeiros, L.J.2    Lai, R.3    Butch, A.W.4    McCourty, A.5    Kelly, K.6    Brynes, R.K.7
  • 50
    • 47949092645 scopus 로고
    • Cysteine and glutathione competition for adduct formation with 2-amino-9-(β-D-ribofuranosyl)purine- 6-sulfinamide (sulfinosine, fin) modulates therapeutic efficacy
    • Crabtree GW, Finch RA, Vasquez KM, et al. Cysteine and glutathione competition for adduct formation with 2-amino-9-(β-D-ribofuranosyl)purine- 6-sulfinamide (sulfinosine, fin) modulates therapeutic efficacy. Proc Am Assoc Cancer Res 1989; 30:597.
    • (1989) Proc Am Assoc Cancer Res , vol.30 , pp. 597
    • Crabtree, G.W.1    Finch, R.A.2    Vasquez, K.M.3
  • 51
    • 47949107157 scopus 로고
    • Isolation, identification, synthesis and therapeutic evaluation of selected metabolites of sulfinosine, a novel purine nucleoside analog active against thiopurine refractory experimental leukemia
    • Riley TA, Finch RA, Vasquez KM, et al. Isolation, identification, synthesis and therapeutic evaluation of selected metabolites of sulfinosine, a novel purine nucleoside analog active against thiopurine refractory experimental leukemia. Proc Am Assoc Cancer Res 1989; 30:599.
    • (1989) Proc Am Assoc Cancer Res , vol.30 , pp. 599
    • Riley, T.A.1    Finch, R.A.2    Vasquez, K.M.3
  • 52
    • 0033231351 scopus 로고    scopus 로고
    • Gene expression and the thiol redox state
    • Arrigo AP. Gene expression and the thiol redox state. Free Radic Biol Med 1999; 27:936-44.
    • (1999) Free Radic Biol Med , vol.27 , pp. 936-944
    • Arrigo, A.P.1
  • 53
    • 0030922309 scopus 로고    scopus 로고
    • DNA elements recognizing NF-Y and Sp1 regulate the human multidrug-resistance gene promoter
    • Sundseth R, MacDonald G, Ting J, King AC. DNA elements recognizing NF-Y and Sp1 regulate the human multidrug-resistance gene promoter. Mol Pharmacol 1997; 51:963-71.
    • (1997) Mol Pharmacol , vol.51 , pp. 963-971
    • Sundseth, R.1    MacDonald, G.2    Ting, J.3    King, A.C.4
  • 54
    • 0141456100 scopus 로고    scopus 로고
    • Modulation of DNA topoisomerase IIalpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors
    • Magan N, Szremska AP, Isaacs RJ, Stowell KM. Modulation of DNA topoisomerase IIalpha promoter activity by members of the Sp (specificity protein) and NF-Y (nuclear factor Y) families of transcription factors. Biochem J 2003; 374:723-9.
    • (2003) Biochem J , vol.374 , pp. 723-729
    • Magan, N.1    Szremska, A.P.2    Isaacs, R.J.3    Stowell, K.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.