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Volumn 297, Issue 4, 2009, Pages

Omega-3 fatty acid supplementation attenuates oxidative stress, inflammation, and tubulointerstitial fibrosis in the remnant kidney

Author keywords

Chronic kidney disease; Epithelial mesenchymal transition; MAP kinase; NAD(P)H oxidase; Smad; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; CYCLOOXYGENASE 2; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; OMEGA 3 FATTY ACID; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P22; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SCATTER FACTOR; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 70349649783     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00217.2009     Document Type: Article
Times cited : (119)

References (40)
  • 2
    • 0022997238 scopus 로고
    • Beneficial effects of polyunsaturated fatty acids in partially nephrectomized rats
    • DOI 10.1016/0090-6980(86)90126-7
    • Barcelli UO, Miyata J, Ito Y, Gallon L, Laskarzewski P, Weiss M, Hitzemann R, Pollak VE. Beneficial effects of polyunsaturated fatty acids in partially nephrectomized rats. Prostaglandins 32: 211-219, 1986. (Pubitemid 17179746)
    • (1986) Prostaglandins , vol.32 , Issue.2 , pp. 211-220
    • Barcelli, U.O.1    Miyata, J.2    Ito, Y.3
  • 3
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • DOI 10.1056/NEJM199411103311907
    • Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 331: 1286-1292, 1994. (Pubitemid 24333194)
    • (1994) New England Journal of Medicine , vol.331 , Issue.19 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 4
    • 34250733867 scopus 로고    scopus 로고
    • The role of tubular epithelial-mesenchymal transition in progressive kidney disease
    • DOI 10.1159/000101323
    • Burns WC, Kantharidis P, Thomas MC. The role of tubular epithelial-mesenchymal transition in progressive kidney disease. Cells Tissues Organs 185: 222-231, 2007. (Pubitemid 46956862)
    • (2007) Cells Tissues Organs , vol.185 , Issue.1-3 , pp. 222-231
    • Burns, W.C.1    Kantharidis, P.2    Thomas, M.C.3
  • 5
    • 67650686808 scopus 로고    scopus 로고
    • Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure
    • Cho K, Kim H, Rodriguez-Iturbe B, Vaziri ND. Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure. Am J Physiol Renal Physiol 297: F106-F113, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Cho, K.1    Kim, H.2    Rodriguez-Iturbe, B.3    Vaziri, N.D.4
  • 6
    • 0026181388 scopus 로고
    • Chronic effects of omega-3 fatty acids (fish oil) in a rat 5/6 renal ablation model
    • Clark WF, Parbtani A, Philbrick DJ, Holub BJ, Huff MW. Chronic effects of omega-3 fatty acids (fish oil) in a rat 5/6 renal ablation model. J Am Soc Nephrol 1: 1343-1353, 1991.
    • (1991) J Am Soc Nephrol , vol.1 , pp. 1343-1353
    • Clark, W.F.1    Parbtani, A.2    Philbrick, D.J.3    Holub, B.J.4    Huff, M.W.5
  • 7
    • 0028172777 scopus 로고
    • The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells
    • De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA Jr, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb 14: 1829-1836, 1994.
    • (1829) Arterioscler Thromb , vol.14 , pp. 1994
    • De Caterina, R.1    Cybulsky, M.I.2    Clinton, S.K.3    Gimbrone Jr., M.A.4    Libby, P.5
  • 9
    • 0032842108 scopus 로고    scopus 로고
    • The long-term outcome of patients with IgA nephropathy treated with fish oil in a controlled trial
    • Mayo Nephrology Collaborative Group
    • Donadio JV Jr, Grande JP, Bergstralh EJ, Dart RA, Larson TS, Spencer DC. The long-term outcome of patients with IgA nephropathy treated with fish oil in a controlled trial. Mayo Nephrology Collaborative Group. J Am Soc Nephrol 10: 1772-1777, 1999.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1772-1777
    • Donadio Jr., J.V.1    Grande, J.P.2    Bergstralh, E.J.3    Dart, R.A.4    Larson, T.S.5    Spencer, D.C.6
  • 11
    • 0345376772 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney
    • DOI 10.1046/j.1523-1755.2003.00319.x
    • Fujihara CK, Antunes GR, Mattar AL, Andreoli N, Malheiros DM, Noronha IL, Zatz R. Cyclooxygenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney. Kidney Int 64: 2172-2181, 2003. (Pubitemid 37449552)
    • (2003) Kidney International , vol.64 , Issue.6 , pp. 2172-2181
    • Fujihara, C.K.1    Antunes, G.R.2    Mattar, A.L.3    Andreoli, N.4    Costa Malheiros, D.M.A.5    Noronha, I.L.6    Zatz, R.7
  • 14
    • 0033802165 scopus 로고    scopus 로고
    • Connective tissue growth factor: Potential role in glomerulosclerosis and tubulointerstitial fibrosis
    • DOI 10.1046/j.1523-1755.2000.00301.x
    • Gupta S, Clarkson MR, Duggan J, Brady HR. Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. Kidney Int 58: 1389-1399, 2000. (Pubitemid 30739645)
    • (2000) Kidney International , vol.58 , Issue.4 , pp. 1389-1399
    • Gupta, S.1    Clarkson, M.R.2    Duggan, J.3    Brady, H.R.4
  • 16
    • 34249287061 scopus 로고    scopus 로고
    • Physiologic and pathophysiologic roles of lipid mediators in the kidney
    • Hao CM, Breyer MD. Physiologic and pathophysiologic roles of lipid mediators in the kidney. Kidney Int 71: 1105-1115, 2007.
    • (2007) Kidney Int , vol.71 , pp. 1105-1115
    • Hao, C.M.1    Breyer, M.D.2
  • 17
    • 4644336694 scopus 로고    scopus 로고
    • Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: Correlation with erythrocytes and response to supplementation
    • DOI 10.1161/01.CIR.0000142292.10048.B2
    • Harris WS, Sands SA, Windsor SL, Ali HA, Stevens TL, Magalski A, Porter CB, Borkon AM. Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: correlation with erythrocytes and response to supplementation. Circulation 110: 1645-1649, 2004. (Pubitemid 39297988)
    • (2004) Circulation , vol.110 , Issue.12 , pp. 1645-1649
    • Harris, W.S.1    Sands, S.A.2    Windsor, S.L.3    Ali, H.A.4    Stevens, T.L.5    Magalski, A.6    Porter, C.B.7    Borkon, A.M.8
  • 19
    • 0037315742 scopus 로고    scopus 로고
    • Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6 nephrectomized mice
    • Inoue T, Okada H, Kobayashi T, Watanabe Y, Kanno Y, Kopp JB, Nishida T, Takigawa M, Ueno M, Nakamura T, Suzuki H. Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6 nephrectomized mice. FASEB J 17: 268-270, 2003.
    • (2003) FASEB J , vol.17 , pp. 268-270
    • Inoue, T.1    Okada, H.2    Kobayashi, T.3    Watanabe, Y.4    Kanno, Y.5    Kopp, J.B.6    Nishida, T.7    Takigawa, M.8    Ueno, M.9    Nakamura, T.10    Suzuki, H.11
  • 20
    • 55449107515 scopus 로고    scopus 로고
    • Regulation of TGF-beta family signaling by E3 ubiquitin ligases
    • Inoue Y, Imamura T. Regulation of TGF-beta family signaling by E3 ubiquitin ligases. Cancer Sci 99: 2107-2112, 2008.
    • (2008) Cancer Sci , vol.99 , pp. 2107-2112
    • Inoue, Y.1    Imamura, T.2
  • 21
    • 0037229290 scopus 로고    scopus 로고
    • Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells
    • DOI 10.1097/00041552-200301000-00005
    • Lan HY. Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 12: 25-29, 2003. (Pubitemid 36092311)
    • (2003) Current Opinion in Nephrology and Hypertension , vol.12 , Issue.1 , pp. 25-29
    • Lan, H.Y.1
  • 22
    • 0037534877 scopus 로고    scopus 로고
    • Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils
    • Leaf A, Kang JX, Xiao YF, Billman GE. Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils. Circulation 107: 2646-2652, 2003. (Pubitemid 36667234)
    • (2003) Circulation , vol.107 , Issue.21 , pp. 2646-2652
    • Leaf, A.1    Kang, J.X.2    Xiao, Y.-F.3    Billman, G.E.4
  • 23
    • 1342268353 scopus 로고    scopus 로고
    • Advanced glycation end products activate Smad signaling via TGF-β-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
    • Li JH, Huang XR, Zhu HJ, Oldfield M, Cooper M, Truong LD, Johnson RJ, Lan HY. Advanced glycation end products activate Smad signaling via TGF-β-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J 18: 176-178, 2004.
    • (2004) FASEB J , vol.18 , pp. 176-178
    • Li, J.H.1    Huang, X.R.2    Zhu, H.J.3    Oldfield, M.4    Cooper, M.5    Truong, L.D.6    Johnson, R.J.7    Lan, H.Y.8
  • 24
    • 1642336325 scopus 로고    scopus 로고
    • Advanced Glycation End Products Induce Tubular Epithelial-Myofibroblast Transition through the RAGE-ERK1/2 MAP Kinase Signaling Pathway
    • Li JH, Wang W, Huang XR, Oldfield M, Schmidt AM, Cooper ME, Lan HY. Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol 164: 1389-1397, 2004. (Pubitemid 38387804)
    • (2004) American Journal of Pathology , vol.164 , Issue.4 , pp. 1389-1397
    • Li, J.H.1    Wang, W.2    Huang, X.R.3    Oldfield, M.4    Schmidt, A.M.5    Cooper, M.E.6    Lan, H.Y.7
  • 25
    • 13144255675 scopus 로고    scopus 로고
    • Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus
    • DOI 10.1016/S0026-0495(97)90148-7
    • Mori Y, Murakawa Y, Katoh S, Hata S, Yokoyama J, Tajima N, Ikeda Y, Nobukata H, Ishikawa T, Shibutani Y. Influence of highly purified eicosapentaenoic acid ethyl ester on insulin resistance in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous noninsul-independent diabetes mellitus. Metabolism 46: 1458-1464, 1997. (Pubitemid 28053213)
    • (1997) Metabolism: Clinical and Experimental , vol.46 , Issue.12 , pp. 1458-1464
    • Mori, Y.1    Murakawa, Y.2    Katoh, S.3    Hata, S.4    Yokoyama, J.5    Tajima, N.6    Ikeda, Y.7    Nobukata, H.8    Ishikawa, T.9    Shibutani, Y.10
  • 27
    • 0038723644 scopus 로고    scopus 로고
    • Participation of the interstitium in acute immune-complex nephritis: Interstitial antigen accumulation, cellular infiltrate, and MHC class II expression
    • DOI 10.1046/j.1365-2249.2003.02188.x
    • Parra G, Hernandez S, Moreno P, Rodriguez-Iturbe B. Participation of the interstitium in acute immune complex nephritis: interstitial antigen accumulation, cellular infiltrate, and MHC class II expression. Clin Exp Immunol 133: 44-49, 2003. (Pubitemid 36791941)
    • (2003) Clinical and Experimental Immunology , vol.133 , Issue.1 , pp. 44-49
    • Parra, G.1    Hernandez, S.2    Moreno, P.3    Rodriguez-Iturbe, B.4
  • 28
    • 38849140938 scopus 로고    scopus 로고
    • Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction
    • DOI 10.1152/ajprenal.00500.2007
    • Quiroz Y, Romero F, Ferrebuz A, Vaziri ND, Rodríguez-Iturbe B. Melatonin ameliorates oxidative stress, inflammation, proteinuria and progression in rats with renal mass reduction. Am J Physiol Renal Physiol 294: F336-F344, 2008. (Pubitemid 351199398)
    • (2008) American Journal of Physiology - Renal Physiology , vol.294 , Issue.2
    • Quiroz, Y.1    Ferrebuz, A.2    Romero, F.3    Vaziri, N.D.4    Rodriguez-Iturbe, B.5
  • 29
    • 32444451549 scopus 로고    scopus 로고
    • Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes
    • DOI 10.1172/JCI27699
    • Remuzzi G, Benigni A, Remuzzi A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. J Clin Invest 116: 288-296, 2006. (Pubitemid 43228342)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.2 , pp. 288-296
    • Remuzzi, G.1    Benigni, A.2    Remuzzi, A.3
  • 30
    • 32644457806 scopus 로고    scopus 로고
    • Mycophenolate mofetil ameliorates nephropathy in the obese Zucker rat
    • DOI 10.1111/j.1523-1755.2005.00496.x, PII 4494681
    • Rodriguez-Iturbe B, Quiroz Y, Shahkarami A, Li Z, Vaziri ND. Mycophenolate mofetil ameliorates nephropathy in the obese Zucker rat. Kidney Int 68: 1041-1047, 2005. (Pubitemid 43246420)
    • (2005) Kidney International , vol.68 , Issue.3 , pp. 1041-1047
    • Rodriguez-Iturbe, B.1    Quiroz, Y.2    Shahkarami, A.3    Li, Z.4    Vaziri, N.D.5
  • 32
    • 36749089036 scopus 로고    scopus 로고
    • Oral fish oil supplementation raises blood omega-3 levels and lowers C-reactive protein in haemodialysis patients - A pilot study
    • DOI 10.1093/ndt/gfm422
    • Saifullah A, Watkins BA, Saha C, Li Y, Moe SM, Friedman AN. Oral fish oil supplementation raises blood omega-3 levels and lowers C-reactive protein in haemodialysis patients - a pilot study. Nephrol Dial Transplant 22: 3561-3567, 2007. (Pubitemid 350212489)
    • (2007) Nephrology Dialysis Transplantation , vol.22 , Issue.12 , pp. 3561-3567
    • Saifullah, A.1    Watkins, B.A.2    Saha, C.3    Li, Y.4    Moe, S.M.5    Friedman, A.N.6
  • 33
    • 57349156568 scopus 로고    scopus 로고
    • Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells
    • Samarakoon R, Higgins PJ. Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells. Thromb Haemost 100: 976-983, 2008.
    • (2008) Thromb Haemost , vol.100 , pp. 976-983
    • Samarakoon, R.1    Higgins, P.J.2
  • 34
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • DOI 10.1172/JCI200319270
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003. (Pubitemid 38056275)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.10 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 37
    • 0037213489 scopus 로고    scopus 로고
    • Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency
    • DOI 10.1046/j.1523-1755.2003.00702.x
    • Vaziri ND, Dicus M, Ho ND, Boroujerdi-Rad L, Sindhu RK. Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. Kidney Int 63: 179-185, 2003. (Pubitemid 35463919)
    • (2003) Kidney International , vol.63 , Issue.1 , pp. 179-185
    • Vaziri, N.D.1    Dicus, M.2    Ho, N.D.3    Boroujerdi-Rad, L.4    Sindhu, R.K.5
  • 38
    • 14844337071 scopus 로고    scopus 로고
    • Transforming growth factor-beta and Smad signalling in kidney diseases
    • DOI 10.1111/j.1440-1797.2005.00334.x
    • Wang W, Koka V, Lan HY. Transforming growth factor-beta and Smad signalling in kidney diseases. Nephrology 10: 48-56, 2005. (Pubitemid 40349406)
    • (2005) Nephrology , vol.10 , Issue.1 , pp. 48-56
    • Wang, W.1    Koka, V.2    Lan, H.Y.3
  • 39
    • 47149083828 scopus 로고    scopus 로고
    • A fishy business: Omega-3 fatty acids and cardiovascular disease
    • Wierzbicki AS. A fishy business: omega-3 fatty acids and cardiovascular disease. Int J Clin Pract 62: 1142-1146, 2008.
    • (2008) Int J Clin Pract , vol.62 , pp. 1142-1146
    • Wierzbicki, A.S.1


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