Molecular dynamics simulation studies of GLUT4: Substrate-free and substrate-induced dynamics and ATP-mediated glucose transport inhibition

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Mohan, Suma ^a   Sheena, Aswathy ^a   Poulose, Ninu ^a   Anilkumar, Gopalakrishnapillai ^a  

^a AMRITA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE TRANSPORTER 4; ISOPROTEIN; ALPHA-GLYCEROPHOSPHORIC ACID; GLUCOSE; GLUCOSE TRANSPORTER 1; GLYCEROPHOSPHATE; SLC2A1 PROTEIN, HUMAN; SLC2A4 PROTEIN, HUMAN;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GLUCOSE TRANSPORT; HYDROGEN BOND; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STABILITY; STRUCTURE ANALYSIS; CHEMISTRY; COMPUTER SIMULATION; GENETICS; HUMAN; LIPID BILAYER; METABOLISM; METHODOLOGY; TRANSPORT AT THE CELLULAR LEVEL; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; GLYCEROPHOSPHATES; HUMANS; HYDROGEN BONDING; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION;

EID: 78649949857     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014217     Document Type: Article

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