Involvement of the p38 pathway in the differential induction of heme oxygenase-1 by statins in Neuro-2A cells exposed to lipopolysaccharide

Drug and Chemical Toxicology

Volumn 34, Issue 1, 2011, Pages 8-19

  Hsieh, Ching Hua ^a   Jeng, Jennifer Chyau Yau ^b   Hsieh, Min Wei ^a   Chen, Yi Chun ^a   Lu, Tsu Hsiang ^a   Rau, Cheng Shyuan ^a   Jeng, Seng Feng ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Atorvastatin; Desferrioxamine (DFO); Heme oxygenase 1 (HO 1); Lipopolysaccharide (LPS); Nuclear factor kappa B (NF ); ; P38; Rosuvastatin; Simvastatin; Superoxide; Zinc protoprophyrin (ZnPP)

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ATORVASTATIN; DEFEROXAMINE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; ROSUVASTATIN; SIMVASTATIN; SUPEROXIDE; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; MOUSE; NERVE CELL; NEURO 2A CELL; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; FLUOROBENZENES; HEME OXYGENASE-1; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IRON; IRON CHELATING AGENTS; LIPOPOLYSACCHARIDES; MICE; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIMIDINES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIMVASTATIN; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 78649937393     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2010.482587     Document Type: Article

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