Differential induction of heme oxygenase-1 against nicotine-induced cytotoxicity via the PI3K, MAPK, and NF-kappa B pathways in immortalized and malignant human oral keratinocytes

Journal of Oral Pathology and Medicine

Volumn 37, Issue 5, 2008, Pages 278-286

  Lee, Hwa Jeong ^a   Lee, Jun ^a   Min, Seung Ki ^a   Guo, Han Young ^a   Lee, Sun Kyung ^a   Kim, Hyung Ryong ^a   Pae, Hyun Ock ^a   Chung, Hun Taeg ^a   Hong, Seung Heon ^a   Lee, Suk Keun ^b   Kim, Eun Cheol ^a  

^a Wonkwang University   (South Korea)

^b Gangneung Wonju National University   (South Korea)

Author keywords

Cytotoxicity; Heme oxygenase 1; Immortalized oral keratinocytes; Mitogen activated protein kinase; Nicotine; Nuclear factor appa B; Oral cancer; PI3 K Akt

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETYLCYSTEINE; ANTIOXIDANT; BILIRUBIN; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NICOTINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR;

ARTICLE; CELL IMMORTALIZATION; CELL PROTECTION; CELL TYPE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME INDUCTION; GINGIVA; HUMAN; HUMAN CELL; KERATINOCYTE; MOUTH CANCER; MOUTH MUCOSA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIME; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIOXIDANTS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; ENZYME INDUCTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GINGIVA; HEME OXYGENASE-1; HUMANS; KERATINOCYTES; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; NICOTINE; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 42149119118     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2007.00616.x     Document Type: Article

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