Epigenetic control of the immune system: Histone demethylation as a target for drug discovery

Drug Discovery Today: Technologies

Volumn 7, Issue 1, 2010, Pages

  Lora, Jose M ^a,b   Wilson, David M ^a   Lee, Kevin ^a   Larminie, Christopher G C ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Department of Structural Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTURATE; 2,4 PYRIDINEDICARBOXYLIC ACID; DICARBOXYLIC ACID DERIVATIVE; DNA; ENZYME; ENZYME INHIBITOR; HISTONE; HISTONE DEMETHYLASE; HISTONE METHYLTRANSFERASE; N OXALYL DEXTRO TYROSINE DERIVATIVE; N OXALYLGLYCINE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ARTICLE; AUTOIMMUNITY; CHROMATIN IMMUNOPRECIPITATION; DEMETHYLATION; DNA SEQUENCE; DRUG MECHANISM; DRUG TARGETING; EPIGENETICS; HUMAN; IMMUNE SYSTEM; INFLAMMATION; INNATE IMMUNITY; METHYLATION; NONHUMAN; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROCESSING;

EID: 78649906287     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2010.10.001     Document Type: Review

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