Salidroside protects human fibroblast cells from premature senescence induced by H2O2 partly through modulating oxidative status

Mechanisms of Ageing and Development

Volumn 131, Issue 11-12, 2010, Pages 723-731

  Mao, Gen Xiang ^a,d   Wang, Yan ^a   Qiu, Qiang ^b   Deng, Hong Bin ^a   Yuan, Long Guo ^a   Li, Rui Guo ^c   Song, Dan Qing ^a   Li, Yi yang Yvonne ^a   Li, Dian Dong ^a   Wang, Zhen ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c China National Center for Biotechnology Development   (China)

^d ZHEJIANG HOSPITAL   (China)

Author keywords

Antioxidant; Cellular senescence; DNA damage; Oxidative stress; Salidroside

Indexed keywords

HYDROGEN PEROXIDE; PROTEIN P16; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SALIDROSIDE; TETRAZOLIUM;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL AGING; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; FETUS; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; LUNG FIBROBLAST; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGING, PREMATURE; ANTIOXIDANTS; BIOLOGICAL MARKERS; CELL AGING; CELL CYCLE; CELL LINE; CYTOPROTECTION; DNA DAMAGE; FIBROBLASTS; GLUCOSIDES; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; PHENOLS; PROTEINS; RHODIOLA; SUPEROXIDE DISMUTASE;

RHODIOLA ROSEA;

EID: 78649905999     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2010.10.003     Document Type: Article

References (44)

1. Anderson D., Yu T.W., Phillips B.J., Schmezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay. Mutat. Res. 1994, 307:261-271.
2. Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev. 1998, 78:547-581.
3. Ben-Porath I., Weinberg R.A. The signals and pathways activating cellular senescence. Int. J. Biochem. Cell Biol. 2005, 37:961-976.
4. Blander G., de Oliveira R.M., Conboy C.M., Haigis M., Guarente L. Superoxide dismutase 1 knock-down induces senescence in human fibroblasts. J. Biol. Chem. 2003, 278:38966-38969.
5. Bokov A., Chaudhuri A., Richardson A. The role of oxidative damage and stress in aging. Mech. Ageing Dev. 2004, 125:811-826.
6. Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120:513-522.
7. Chen L., Jiang J., Cheng C., Yang A., He Q., Li D., Wang Z. P53 dependent and independent apoptosis induced by lidamycin in human colorectal cancer cells. Cancer Biol. Ther. 2007, 6:965-973.
8. Chen Q., Ames B.N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:4130-4134.
9. Chen Q.M. Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints. Ann. N. Y. Acad. Sci. 2000, 908:111-125.
10. 2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem. J. 1998, 332(Pt 1):43-50.
11. Chiu C.P., Harley C.B. Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc. Soc. Exp. Biol. Med. 1997, 214:99-106.
12. Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O., et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:9363-9367.
13. Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
14. Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11:298-300.
15. He Q.Y., Liang Y.Y., Wang D.S., Li D.D. Characteristics of mitotic cell death induced by enediyne antibiotic lidamycin in human epithelial tumor cells. Int. J. Oncol. 2002, 20:261-266.
16. Itahana K., Zou Y., Itahana Y., Martinez J.L., Beausejour C., Jacobs J.J., Van Lohuizen M., Band V., Campisi J., Dimri G.P. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol. Cell. Biol. 2003, 23:389-401.
17. Jang Y.C., Remmen V.H. The mitochondrial theory of aging: insight from transgenic and knockout mouse models. Exp. Gerontol. 2009, 44:256-260.
18. Kelly G.S. Rhodiola rosea: a possible plant adaptogen. Altern. Med. Rev. 2001, 6:293-302.
19. Kim S.H., Hyun S.H., Choung S.Y. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. Biofactors 2006, 26:209-219.
20. Lenaz G., D'Aurelio M., Merlo Pich M., Genova M.L., Ventura B., Bovina C., Formiggini G., Parenti Castelli G. Mitochondrial bioenergetics in aging. Biochim. Biophys. Acta 2000, 1459:397-404.
21. Li J., Zhang Z., Tong T. The proliferative response and anti-oncogene expression in old 2BS cells after growth factor stimulation. Mech. Ageing Dev. 1995, 80:25-34.
22. Loeb L.A., Wallace D.C., Martin G.M. The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:18769-18770.
23. Mao G.X., Deng H.B., Yuan L.G., Li D.D., Li Y.Y., Wang Z. Protective role of salidroside against aging in a mouse model induced by d-galactose. Biomed. Environ. Sci. 2010, 23:161-166.
24. Martin-Ruiz C., Saretzki G., Petrie J., Ladhoff J., Jeyapalan J., Wei W., Sedivy J., von Zglinicki T. Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. J. Biol. Chem. 2004, 279:17826-17833.
25. Ohtani N., Yamakoshi K., Takahashi A., Hara E. The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression. J. Med. Invest. 2004, 51:146-153.
26. Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., Boulianne G.L. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat. Genet. 1998, 19:171-174.
27. Petkov V.D., Yonkov D., Mosharoff A., Kambourova T., Alova L., Petkov V.V., Todorov I. Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory. Acta Physiol. Pharmacol. Bulg. 1986, 12:3-16.
28. Schriner S.E., Abrahamyan A., Avanessian A., Bussel I., Maler S., Gazarian M., Holmbeck M.A., Jafari M. Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea. Free Radic. Res. 2009, 43:836-843.
29. Schriner S.E., Avanesian A., Liu Y., Luesch H., Jafari M. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses. Free Radic. Biol. Med. 2009, 47:577-584.
30. Tang Z., Zhang Z., Zheng Y., Corbley M.J., Tong T. Cell aging of human diploid fibroblasts is associated with changes in responsiveness to epidermal growth factor and changes in HER-2 expression. Mech. Ageing Dev. 1994, 73:57-67.
31. Toussaint O., Medrano E.E., von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp. Gerontol. 2000, 35:927-945.
32. Udintsev S.N., Shakhov V.P. The role of humoral factors of regenerating liver in the development of experimental tumors and the effect of Rhodiola rosea extract on this process. Neoplasma 1991, 38:323-331.
33. Verdun R.E., Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 2006, 127:709-720.
34. Vidal A., Koff A. Cell-cycle inhibitors: three families united by a common cause. Gene 2000, 247:1-15.
35. von Zglinicki T. Role of oxidative stress in telomere length regulation and replicative senescence. Ann. N. Y. Acad. Sci. 2000, 908:99-110.
36. von Zglinicki T., Saretzki G., Ladhoff J., d'Adda di Fagagna F., Jackson S.P. Human cell senescence as a DNA damage response. Mech. Ageing Dev. 2005, 126:111-117.
37. Wang P., Zhang Z., Ma X., Huang Y., Liu X., Tu P., Tong T. HDTIC-1 and HDTIC-2, two compounds extracted from Astragali Radix, delay replicative senescence of human diploid fibroblasts. Mech. Ageing Dev. 2003, 124:1025-1034.
38. Wang Z., Sun Y. Targeting p53 for novel anticancer therapy. Transl. Oncol. 2010, 3:1-12.
39. Wiegant F.A., Surinova S., Ytsma E., Langelaar-Makkinje M., Wikman G., Post J.A. Plant adaptogens increase lifespan and stress resistance in C. elegans. Biogerontology 2009, 10:27-42.
40. Wu Y.L., Lian L.H., Jiang Y.Z., Nan J.X. Hepatoprotective effects of salidroside on fulminant hepatic failure induced by d-galactosamine and lipopolysaccharide in mice. J. Pharm. Pharmacol. 2009, 61:1375-1382.
41. Yang X., Zhao Y., Zhou Y., Lv Y., Mao J., Zhao P. Component and antioxidant properties of polysaccharide fractions isolated from Angelica sinensis (OLIV.) DIELS. Biol. Pharm. Bull. 2007, 30:1884-1890.
42. Yu S., Liu M., Gu X., Ding F. Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation. Cell. Mol. Neurobiol. 2008, 28:1067-1078.
43. Yu S., Shen Y., Liu J., Ding F. Involvement of ERK1/2 pathway in neuroprotection by salidroside against hydrogen peroxide-induced apoptotic cell death. J. Mol. Neurosci. 2010, 40:321-331.
44. Zhang L., Yu H., Sun Y., Lin X., Chen B., Tan C., Cao G., Wang Z. Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells. Eur. J. Pharmacol. 2007, 564:18-25.