Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8- tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect

Journal of Biological Chemistry

Volumn 285, Issue 50, 2010, Pages 38801-38810

  Diani Moore, Silvia ^a   Ram, Payal ^a   Li, Xintian ^a,b   Mondal, Prosenjit ^a   Youn, Dou Yeon ^a   Sauve, Anthony A ^a   Rifkind, Arleen B ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYL HYDROCARBON RECEPTOR; COACTIVATORS; CYTOCHROMES P450; ENVIRONMENTAL TOXINS; GLUCONEOGENESIS; GLUCONEOGENIC GENES; GLUCOSE PRODUCTION; GLUCOSE-6-PHOSPHATASE; HEPATIC GLUCONEOGENESIS; OVER-EXPRESSION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE; POLY POLYMERASE; PROTEOSOMAL DEGRADATION; TARGET GENES; TETRACHLORODIBENZO P DIOXINS; TOXIC EFFECT; UBIQUITIN;

ACETYLATION; AMIDES; CYTOLOGY; ENZYME INHIBITION; GENES; GLUCOSE; HYDROCARBONS; METABOLISM; TOXICITY; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN INDUCIBLE POLY(ADENOSINE DIPHOSPHATE RIBOSE); AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; GLUCONEOGENESIS; LIVER; LIVER CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHICK EMBRYO; CYTOCHROME P-450 CYP1A1; GENE SILENCING; GLUCOSE; GLYCOGEN; HEPATOCYTES; LIVER; NAD; NIACINAMIDE; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, ARYL HYDROCARBON; SIRTUIN 1; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION FACTORS;

EID: 78649901987     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.131573     Document Type: Article

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