Phosphodiesterase 4B is essential for TH2-cell function and development of airway hyperresponsiveness in allergic asthma

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 6, 2010, Pages

  Jin, S L Catherine ^b,e   Goya, Sho ^c   Nakae, Susumu ^d   Wang, Dan ^a   Bruss, Matthew ^e   Hou, Chiaoyin ^b   Umetsu, Dale ^c   Conti, Marco ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF TOKYO   (Japan)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

airway hyperresponsiveness; airway inflammation; Asthma; cAMP signaling; PDE4B

Indexed keywords

GAMMA INTERFERON; METHACHOLINE; OVALBUMIN; PHOSPHODIESTERASE 4B; PHOSPHODIESTERASE IV; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE COURSE; IN VITRO STUDY; LEUKOCYTE; LUNG LAVAGE; LYMPH NODE CELL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; WILD TYPE;

EID: 78649829956     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.08.014     Document Type: Article

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