Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Cohen, Joseph R ^a,b   Resnick, Daniel Z ^a,c   Niewiadomski, Pawel ^a,d   Dong, Hongmei ^a   Liau, Linda M ^e   Waschek, James A ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN P53; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; ADCYAP1 PROTEIN, MOUSE; ADCYAP1R1 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; ENZYME ACTIVATOR; G PROTEIN COUPLED RECEPTOR; GLI PROTEIN, MOUSE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR 1; ISOQUINOLINE DERIVATIVE; KRUPPEL LIKE FACTOR; MORPHOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PATCHED RECEPTORS; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PURINE DERIVATIVE; PURMORPHAMINE; PYRAZOLE DERIVATIVE; SANT 1 COMPOUND; SANT-1 COMPOUND; SMO PROTEIN, MOUSE; SULFONAMIDE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; MEDULLOBLASTOMA; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; CEREBELLUM TUMOR; DOSE RESPONSE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GENETICS; METABOLISM; MOUSE MUTANT; MULTICELLULAR SPHEROID; PATHOLOGY; POLYMERASE CHAIN REACTION; TIME; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CEREBELLAR NEOPLASMS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATORS; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; ISOQUINOLINES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEDULLOBLASTOMA; MICE; MICE, KNOCKOUT; MORPHOLINES; PIPERAZINES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POLYMERASE CHAIN REACTION; PROTEIN KINASE INHIBITORS; PURINES; PYRAZOLES; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; SULFONAMIDES; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78649778509     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-676     Document Type: Article

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