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Volumn 5, Issue 11, 2010, Pages

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ALITRETINOIN; CAPTOPRIL; EPIGALLOCATECHIN GALLATE; ESTROGEN; LOSARTAN; METRIBOLONE; MYOSIN HEAVY CHAIN; PROTEIN INHIBITOR; RELAXIN; RESVERATROL; RETINOIC ACID; SIS 3; SMAD3 PROTEIN; TRANILAST; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VITAMIN D; 1,3 DIOXOLANE DERIVATIVE; 4 (5 BENZO(1,3)DIOXOL 5 YL 4 PYRIDIN 2 YL 1H IMIDAZOL 2 YL)BENZAMIDE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; ANTIOXIDANT; BENZAMIDE DERIVATIVE; CATECHIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DRUG DERIVATIVE; STILBENE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VITAMIN;

EID: 78649776286     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015511     Document Type: Article
Times cited : (19)

References (97)
  • 1
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 2
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-beta-Smad signalling
    • ten Dijke P, Hill CS (2004) New insights into TGF-beta-Smad signalling. Trends Biochem Sci 29: 265-273.
    • (2004) Trends Biochem Sci , vol.29 , pp. 265-273
    • ten Dijke, P.1    Hill, C.S.2
  • 3
    • 27244462856 scopus 로고
    • TGF-beta: Problems and prospects
    • Sporn MB, Roberts AB (1990) TGF-beta: problems and prospects. Cell Regul 1: 875-882.
    • (1990) Cell Regul , vol.1 , pp. 875-882
    • Sporn, M.B.1    Roberts, A.B.2
  • 4
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • Siegel PM, Massague J (2003) Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 3: 807-821.
    • (2003) Nat Rev Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 5
    • 75749131647 scopus 로고    scopus 로고
    • Narrative review: Fibrotic diseases: Cellular and molecular mechanisms and novel therapies
    • Rosenbloom J, Castro SV, Jimenez SA (2010) Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann Intern Med 152: 159-166.
    • (2010) Ann Intern Med , vol.152 , pp. 159-166
    • Rosenbloom, J.1    Castro, S.V.2    Jimenez, S.A.3
  • 6
    • 0011899697 scopus 로고
    • Type beta transforming growth factor is an inhibitor of myogenic differentiation
    • Massague J, Cheifetz S, Endo T, Nadal-Ginard B (1986) Type beta transforming growth factor is an inhibitor of myogenic differentiation. Proc Natl Acad SciUS A 83: 8206-8210.
    • (1986) Proc Natl Acad SciUS A , vol.83 , pp. 8206-8210
    • Massague, J.1    Cheifetz, S.2    Endo, T.3    Nadal-Ginard, B.4
  • 7
    • 0022977185 scopus 로고
    • Regulation of myogenic differentiation by type beta transforming growth factor
    • Olson EN, Sternberg E, Hu JS, Spizz G, Wilcox C (1986) Regulation of myogenic differentiation by type beta transforming growth factor. J Cell Biol 103: 1799-1805.
    • (1986) J Cell Biol , vol.103 , pp. 1799-1805
    • Olson, E.N.1    Sternberg, E.2    Hu, J.S.3    Spizz, G.4    Wilcox, C.5
  • 8
    • 0025909860 scopus 로고
    • Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding
    • Brennan TJ, Edmondson DG, Li L, Olson EN (1991) Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. Proc Natl Acad Sci U S A 88: 3822-3826.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3822-3826
    • Brennan, T.J.1    Edmondson, D.G.2    Li, L.3    Olson, E.N.4
  • 9
    • 0035890328 scopus 로고    scopus 로고
    • TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
    • Liu D, Black BL, Derynck R (2001) TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev 15: 2950-2966.
    • (2001) Genes Dev , vol.15 , pp. 2950-2966
    • Liu, D.1    Black, B.L.2    Derynck, R.3
  • 10
    • 2342514242 scopus 로고    scopus 로고
    • TGF-beta-activated Smad3 represses MEF2- dependent transcription in myogenic differentiation
    • Liu D, Kang JS, Derynck R (2004) TGF-beta-activated Smad3 represses MEF2- dependent transcription in myogenic differentiation. EMBO J 23: 1557-1566.
    • (2004) EMBO J , vol.23 , pp. 1557-1566
    • Liu, D.1    Kang, J.S.2    Derynck, R.3
  • 12
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron AC, Lawler AM, Lee SJ (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387: 83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 13
    • 0036436583 scopus 로고    scopus 로고
    • The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis
    • Amthor H, Huang R, McKinnell I, Christ B, Kambadur R, et al. (2002) The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis. Dev Biol 251: 241-257.
    • (2002) Dev Biol , vol.251 , pp. 241-257
    • Amthor, H.1    Huang, R.2    McKinnell, I.3    Christ, B.4    Kambadur, R.5
  • 14
    • 0032991133 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 and fibrosis in congenital muscular dystrophies
    • Bernasconi P, Di Blasi C, Mora M, Morandi L, Galbiati S, et al. (1999) Transforming growth factor-beta1 and fibrosis in congenital muscular dystrophies. Neuromuscul Disord 9: 28-33.
    • (1999) Neuromuscul Disord , vol.9 , pp. 28-33
    • Bernasconi, P.1    Di Blasi, C.2    Mora, M.3    Morandi, L.4    Galbiati, S.5
  • 15
    • 7444244384 scopus 로고    scopus 로고
    • Localization and early time course of TGF-beta 1 mRNA expression in dystrophic muscle
    • Gosselin LE, Williams JE, Deering M, Brazeau D, Koury S, et al. (2004) Localization and early time course of TGF-beta 1 mRNA expression in dystrophic muscle. Muscle Nerve 30: 645-653.
    • (2004) Muscle Nerve , vol.30 , pp. 645-653
    • Gosselin, L.E.1    Williams, J.E.2    Deering, M.3    Brazeau, D.4    Koury, S.5
  • 16
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G (1993) Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122: 103-111.
    • (1993) J Cell Biol , vol.122 , pp. 103-111
    • Desmouliere, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 18
    • 1242293760 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: A key event in muscle fibrogenesis
    • Li Y, Foster W, Deasy BM, Chan Y, Prisk V, et al. (2004) Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis. Am J Pathol 164: 1007-1019.
    • (2004) Am J Pathol , vol.164 , pp. 1007-1019
    • Li, Y.1    Foster, W.2    Deasy, B.M.3    Chan, Y.4    Prisk, V.5
  • 19
    • 0036731863 scopus 로고    scopus 로고
    • Differentiation of muscle-derived cells into myofibroblasts in injured skeletal muscle
    • Li Y, Huard J (2002) Differentiation of muscle-derived cells into myofibroblasts in injured skeletal muscle. Am J Pathol 161: 895-907.
    • (2002) Am J Pathol , vol.161 , pp. 895-907
    • Li, Y.1    Huard, J.2
  • 20
    • 33846946114 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states
    • Cohn RD, van Erp C, Habashi JP, Soleimani AA, Klein EC, et al. (2007) Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med 13: 204-210.
    • (2007) Nat Med , vol.13 , pp. 204-210
    • Cohn, R.D.1    van Erp, C.2    Habashi, J.P.3    Soleimani, A.A.4    Klein, E.C.5
  • 21
    • 22044450950 scopus 로고    scopus 로고
    • Bone marrow stromal cells generate muscle cells and repair muscle degeneration
    • Dezawa M, Ishikawa H, Itokazu Y, Yoshihara T, Hoshino M, et al. (2005) Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 309: 314-317.
    • (2005) Science , vol.309 , pp. 314-317
    • Dezawa, M.1    Ishikawa, H.2    Itokazu, Y.3    Yoshihara, T.4    Hoshino, M.5
  • 22
    • 34247236574 scopus 로고    scopus 로고
    • Stem and progenitor cells in skeletal muscle development, maintenance, and therapy
    • Peault B, Rudnicki M, Torrente Y, Cossu G, Tremblay JP, et al. (2007) Stem and progenitor cells in skeletal muscle development, maintenance, and therapy. Mol Ther 15: 867-877.
    • (2007) Mol Ther , vol.15 , pp. 867-877
    • Peault, B.1    Rudnicki, M.2    Torrente, Y.3    Cossu, G.4    Tremblay, J.P.5
  • 23
    • 0034213815 scopus 로고    scopus 로고
    • Regenerative capacity and the number of satellite cells in soleus muscles of normal and mdx mice
    • Reimann J, Irintchev A, Wernig A (2000) Regenerative capacity and the number of satellite cells in soleus muscles of normal and mdx mice. Neuromuscul Disord 10: 276-282.
    • (2000) Neuromuscul Disord , vol.10 , pp. 276-282
    • Reimann, J.1    Irintchev, A.2    Wernig, A.3
  • 24
    • 29244453607 scopus 로고    scopus 로고
    • Neutralization of transforming growth factor-beta attenuates hypertension and prevents renal injury in uremic rats
    • Lavoie P, Robitaille G, Agharazii M, Ledbetter S, Lebel M, et al. (2005) Neutralization of transforming growth factor-beta attenuates hypertension and prevents renal injury in uremic rats. J Hypertens 23: 1895-1903.
    • (2005) J Hypertens , vol.23 , pp. 1895-1903
    • Lavoie, P.1    Robitaille, G.2    Agharazii, M.3    Ledbetter, S.4    Lebel, M.5
  • 25
    • 0035852766 scopus 로고    scopus 로고
    • Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy
    • Lim DS, Lutucuta S, Bachireddy P, Youker K, Evans A, et al. (2001) Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation 103: 789-791.
    • (2001) Circulation , vol.103 , pp. 789-791
    • Lim, D.S.1    Lutucuta, S.2    Bachireddy, P.3    Youker, K.4    Evans, A.5
  • 26
    • 33645688929 scopus 로고    scopus 로고
    • Enhanced effect of combined treatment with SMP-534 (antifibrotic agent) and losartan in diabetic nephropathy
    • Sugaru E, Nakagawa T, Ono-Kishino M, Nagamine J, Tokunaga T, et al. (2006) Enhanced effect of combined treatment with SMP-534 (antifibrotic agent) and losartan in diabetic nephropathy. Am J Nephrol 26: 50-58.
    • (2006) Am J Nephrol , vol.26 , pp. 50-58
    • Sugaru, E.1    Nakagawa, T.2    Ono-Kishino, M.3    Nagamine, J.4    Tokunaga, T.5
  • 27
    • 33846482639 scopus 로고    scopus 로고
    • Amelioration of established diabetic nephropathy by combined treatment with SMP-534 (antifibrotic agent) and losartan in db/db mice
    • Sugaru E, Nakagawa T, Ono-Kishino M, Nagamine J, Tokunaga T, et al. (2007) Amelioration of established diabetic nephropathy by combined treatment with SMP-534 (antifibrotic agent) and losartan in db/db mice. Nephron Exp Nephrol 105: e45-e52.
    • (2007) Nephron Exp Nephrol , vol.105
    • Sugaru, E.1    Nakagawa, T.2    Ono-Kishino, M.3    Nagamine, J.4    Tokunaga, T.5
  • 28
    • 15844402989 scopus 로고    scopus 로고
    • Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect
    • Yu L, Border WA, Anderson I, McCourt M, Huang Y, et al. (2004) Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect. Kidney Int 66: 1774-1784.
    • (2004) Kidney Int , vol.66 , pp. 1774-1784
    • Yu, L.1    Border, W.A.2    Anderson, I.3    McCourt, M.4    Huang, Y.5
  • 29
    • 10444261212 scopus 로고    scopus 로고
    • Development of TGF-beta signalling inhibitors for cancer therapy
    • Yingling JM, Blanchard KL, Sawyer JS (2004) Development of TGF-beta signalling inhibitors for cancer therapy. Nat Rev Drug Discov 3: 1011-1022.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 1011-1022
    • Yingling, J.M.1    Blanchard, K.L.2    Sawyer, J.S.3
  • 30
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, et al. (2002) SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62: 65-74.
    • (2002) Mol Pharmacol , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5
  • 31
    • 77951280181 scopus 로고    scopus 로고
    • SB431542 treatment promotes the hypertrophy of skeletal muscle fibers but decreases specific force
    • Watt KI, Jaspers RT, Atherton P, Smith K, Rennie MJ, et al. (2010) SB431542 treatment promotes the hypertrophy of skeletal muscle fibers but decreases specific force. Muscle & Nerve.
    • (2010) Muscle & Nerve
    • Watt, K.I.1    Jaspers, R.T.2    Atherton, P.3    Smith, K.4    Rennie, M.J.5
  • 32
    • 73449089494 scopus 로고    scopus 로고
    • Companies waver in efforts to target transforming growth factor beta in cancer
    • Garber K (2009) Companies waver in efforts to target transforming growth factor beta in cancer. J Natl Cancer Inst 101: 1664-1667.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1664-1667
    • Garber, K.1
  • 33
    • 76649100088 scopus 로고    scopus 로고
    • TGF-beta in the pathogenesis and prevention of disease: A matter of aneurysmic proportions
    • Dietz HC (2010) TGF-beta in the pathogenesis and prevention of disease: a matter of aneurysmic proportions. J Clin Invest 120: 403-407.
    • (2010) J Clin Invest , vol.120 , pp. 403-407
    • Dietz, H.C.1
  • 34
    • 0032907332 scopus 로고    scopus 로고
    • Differentiation markers of mouse C2C12 and rat L6 myogenic cell lines and the effect of the differentiation medium
    • Portier GL, Benders AG, Oosterhof A, Veerkamp JH, van Kuppevelt TH (1999) Differentiation markers of mouse C2C12 and rat L6 myogenic cell lines and the effect of the differentiation medium. In Vitro Cell Dev Biol Anim 35: 219-227.
    • (1999) Vitro Cell Dev Biol Anim , vol.35 , pp. 219-227
    • Portier, G.L.1    Benders, A.G.2    Oosterhof, A.3    Veerkamp, J.H.4    van Kuppevelt, T.H.5
  • 35
    • 33845882497 scopus 로고    scopus 로고
    • Variation in ACE activity affects myogenic differentiation in C2C12 cells
    • Mori S, Tokuyama K (2007) Variation in ACE activity affects myogenic differentiation in C2C12 cells. Biochem Biophys Res Commun 353: 369-375.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 369-375
    • Mori, S.1    Tokuyama, K.2
  • 36
    • 1342343891 scopus 로고    scopus 로고
    • An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis
    • De Albuquerque DA, Saxena V, Adams DE, Boivin GP, Brunner HI, et al. (2004) An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis. Kidney Int 65: 846-859.
    • (2004) Kidney Int , vol.65 , pp. 846-859
    • de Albuquerque, D.A.1    Saxena, V.2    Adams, D.E.3    Boivin, G.P.4    Brunner, H.I.5
  • 37
    • 4644308778 scopus 로고    scopus 로고
    • Prevention of fibrosis in experimental colitis by captopril: The role of tgf-beta1
    • Wengrower D, Zanninelli G, Pappo O, Latella G, Sestieri M, et al. (2004) Prevention of fibrosis in experimental colitis by captopril: the role of tgf-beta1. Inflamm Bowel Dis 10: 536-545.
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 536-545
    • Wengrower, D.1    Zanninelli, G.2    Pappo, O.3    Latella, G.4    Sestieri, M.5
  • 38
    • 34848830408 scopus 로고    scopus 로고
    • ACE activity affects myogenic differentiation via mTOR signaling
    • Mori S, Tokuyama K (2007) ACE activity affects myogenic differentiation via mTOR signaling. Biochem Biophys Res Commun 363: 597-602.
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 597-602
    • Mori, S.1    Tokuyama, K.2
  • 39
    • 67650609666 scopus 로고    scopus 로고
    • Tranilast inhibits hormone refractory prostate cancer cell proliferation and suppresses transforming growth factor beta1-associated osteoblastic changes
    • Izumi K, Mizokami A, Li YQ, Narimoto K, Sugimoto K, et al. (2009) Tranilast inhibits hormone refractory prostate cancer cell proliferation and suppresses transforming growth factor beta1-associated osteoblastic changes. Prostate 69: 1222-1234.
    • (2009) Prostate , vol.69 , pp. 1222-1234
    • Izumi, K.1    Mizokami, A.2    Li, Y.Q.3    Narimoto, K.4    Sugimoto, K.5
  • 41
    • 23044431799 scopus 로고    scopus 로고
    • Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells
    • Iwata Y, Katanosaka Y, Shijun Z, Kobayashi Y, Hanada H, et al. (2005) Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells. Biochem Pharmacol 70: 740-751.
    • (2005) Biochem Pharmacol , vol.70 , pp. 740-751
    • Iwata, Y.1    Katanosaka, Y.2    Shijun, Z.3    Kobayashi, Y.4    Hanada, H.5
  • 42
    • 31044448265 scopus 로고    scopus 로고
    • Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression
    • Jinnin M, Ihn H, Tamaki K (2006) Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol 69: 597-607.
    • (2006) Mol Pharmacol , vol.69 , pp. 597-607
    • Jinnin, M.1    Ihn, H.2    Tamaki, K.3
  • 43
    • 50349094996 scopus 로고    scopus 로고
    • Myostatin directly regulates skeletal muscle fibrosis
    • Li ZB, Kollias HD, Wagner KR (2008) Myostatin directly regulates skeletal muscle fibrosis. J Biol Chem 283: 19371-19378.
    • (2008) J Biol Chem , vol.283 , pp. 19371-19378
    • Li, Z.B.1    Kollias, H.D.2    Wagner, K.R.3
  • 44
    • 24344505830 scopus 로고    scopus 로고
    • Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation
    • Yun BG, Matts RL (2005) Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation. Cell Signal 17: 1477-1485.
    • (2005) Cell Signal , vol.17 , pp. 1477-1485
    • Yun, B.G.1    Matts, R.L.2
  • 46
    • 48249099342 scopus 로고    scopus 로고
    • Critical regulation of TGFbeta signaling by Hsp90
    • Wrighton KH, Lin X, Feng XH (2008) Critical regulation of TGFbeta signaling by Hsp90. Proc Natl Acad Sci U S A 105: 9244-9249.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9244-9249
    • Wrighton, K.H.1    Lin, X.2    Feng, X.H.3
  • 47
    • 24944542890 scopus 로고    scopus 로고
    • The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway
    • Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, et al. (2005) The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway. Kidney Int 68: 96-109.
    • (2005) Kidney Int , vol.68 , pp. 96-109
    • Heeg, M.H.1    Koziolek, M.J.2    Vasko, R.3    Schaefer, L.4    Sharma, K.5
  • 48
    • 28344434182 scopus 로고    scopus 로고
    • The effect of relaxin treatment on skeletal muscle injuries
    • Negishi S, Li Y, Usas A, Fu FH, Huard J (2005) The effect of relaxin treatment on skeletal muscle injuries. Am J Sports Med 33: 1816-1824.
    • (2005) Am J Sports Med , vol.33 , pp. 1816-1824
    • Negishi, S.1    Li, Y.2    Usas, A.3    Fu, F.H.4    Huard, J.5
  • 49
    • 34548062188 scopus 로고    scopus 로고
    • Relaxin: Antifibrotic properties and effects in models of disease
    • Samuel CS (2005) Relaxin: antifibrotic properties and effects in models of disease. Clin Med Res 3: 241-249.
    • (2005) Clin Med Res , vol.3 , pp. 241-249
    • Samuel, C.S.1
  • 50
    • 71549162551 scopus 로고    scopus 로고
    • Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: A comparison study with methylprednisolone
    • Messina S, Bitto A, Aguennouz M, Mazzeo A, Migliorato A, et al. (2009) Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: a comparison study with methylprednisolone. Exp Neurol 220: 349-358.
    • (2009) Exp Neurol , vol.220 , pp. 349-358
    • Messina, S.1    Bitto, A.2    Aguennouz, M.3    Mazzeo, A.4    Migliorato, A.5
  • 51
    • 70450123699 scopus 로고    scopus 로고
    • Resveratrol: A natural polyphenol with multiple chemopreventive properties
    • Brisdelli F, D'Andrea G, Bozzi A (2009) Resveratrol: a natural polyphenol with multiple chemopreventive properties. Curr Drug Metab 10: 530-546.
    • (2009) Curr Drug Metab , vol.10 , pp. 530-546
    • Brisdelli, F.1    D'Andrea, G.2    Bozzi, A.3
  • 52
    • 63349112144 scopus 로고    scopus 로고
    • Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes
    • Hemdan DI, Hirasaka K, Nakao R, Kohno S, Kagawa S, et al. (2009) Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. J Med Invest 56: 26-32.
    • (2009) J Med Invest , vol.56 , pp. 26-32
    • Hemdan, D.I.1    Hirasaka, K.2    Nakao, R.3    Kohno, S.4    Kagawa, S.5
  • 53
    • 34247600642 scopus 로고    scopus 로고
    • Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
    • Park CE, Kim MJ, Lee JH, Min BI, Bae H, et al. (2007) Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase. Exp Mol Med 39: 222-229.
    • (2007) Exp Mol Med , vol.39 , pp. 222-229
    • Park, C.E.1    Kim, M.J.2    Lee, J.H.3    Min, B.I.4    Bae, H.5
  • 54
    • 65049089489 scopus 로고    scopus 로고
    • Cellular effects of resveratrol in skeletal muscle
    • Dirks Naylor AJ (2009) Cellular effects of resveratrol in skeletal muscle. Life Sci 84: 637-640.
    • (2009) Life Sci , vol.84 , pp. 637-640
    • Dirks, N.A.J.1
  • 55
    • 9144264926 scopus 로고    scopus 로고
    • Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation
    • Wyke SM, Russell ST, Tisdale MJ (2004) Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Br J Cancer 91: 1742-1750.
    • (2004) Br J Cancer , vol.91 , pp. 1742-1750
    • Wyke, S.M.1    Russell, S.T.2    Tisdale, M.J.3
  • 56
    • 41049092846 scopus 로고    scopus 로고
    • Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: A quantitative histological, immunohistochemical and electrophysiological study
    • Nakae Y, Hirasaka K, Goto J, Nikawa T, Shono M, et al. (2008) Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: a quantitative histological, immunohistochemical and electrophysiological study. Histochem Cell Biol 129: 489-501.
    • (2008) Histochem Cell Biol , vol.129 , pp. 489-501
    • Nakae, Y.1    Hirasaka, K.2    Goto, J.3    Nikawa, T.4    Shono, M.5
  • 57
    • 67651022162 scopus 로고    scopus 로고
    • Mouse model of testosterone-induced muscle fiber hypertrophy: Involvement of p38 mitogenactivated protein kinase-mediated Notch signaling
    • Brown D, Hikim AP, Kovacheva EL, Sinha-Hikim I (2009) Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of p38 mitogenactivated protein kinase-mediated Notch signaling. J Endocrinol 201: 129-139.
    • (2009) J Endocrinol , vol.201 , pp. 129-139
    • Brown, D.1    Hikim, A.P.2    Kovacheva, E.L.3    Sinha-Hikim, I.4
  • 58
    • 74949086718 scopus 로고    scopus 로고
    • Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways
    • Kovacheva EL, Hikim AP, Shen R, Sinha I, Sinha-Hikim I. Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways. Endocrinology 151: 628-638.
    • Endocrinology , vol.151 , pp. 628-638
    • Kovacheva, E.L.1    Hikim, A.P.2    Shen, R.3    Sinha, I.4    Sinha-Hikim, I.5
  • 59
    • 14844293101 scopus 로고    scopus 로고
    • Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene
    • Vlahopoulos S, Zimmer WE, Jenster G, Belaguli NS, Balk SP, et al. (2005) Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene. J Biol Chem 280: 7786-7792.
    • (2005) J Biol Chem , vol.280 , pp. 7786-7792
    • Vlahopoulos, S.1    Zimmer, W.E.2    Jenster, G.3    Belaguli, N.S.4    Balk, S.P.5
  • 60
    • 33846253532 scopus 로고    scopus 로고
    • SRF is a nuclear repressor of Smad3-mediated TGF-beta signaling
    • Lee HJ, Yun CH, Lim SH, Kim BC, Baik KG, et al. (2007) SRF is a nuclear repressor of Smad3-mediated TGF-beta signaling. Oncogene 26: 173-185.
    • (2007) Oncogene , vol.26 , pp. 173-185
    • Lee, H.J.1    Yun, C.H.2    Lim, S.H.3    Kim, B.C.4    Baik, K.G.5
  • 61
    • 0037059735 scopus 로고    scopus 로고
    • The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3
    • Chipuk JE, Cornelius SC, Pultz NJ, Jorgensen JS, Bonham MJ, et al. (2002) The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3. J Biol Chem 277: 1240-1248.
    • (2002) J Biol Chem , vol.277 , pp. 1240-1248
    • Chipuk, J.E.1    Cornelius, S.C.2    Pultz, N.J.3    Jorgensen, J.S.4    Bonham, M.J.5
  • 62
    • 0035900710 scopus 로고    scopus 로고
    • Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3
    • Matsuda T, Yamamoto T, Muraguchi A, Saatcioglu F (2001) Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3. J Biol Chem 276: 42908-42914.
    • (2001) J Biol Chem , vol.276 , pp. 42908-42914
    • Matsuda, T.1    Yamamoto, T.2    Muraguchi, A.3    Saatcioglu, F.4
  • 63
    • 72849137025 scopus 로고    scopus 로고
    • The influence of estrogen on skeletal muscle: Sex matters
    • Enns DL, Tiidus PM (2010) The influence of estrogen on skeletal muscle: sex matters. Sports Med 40: 41-58.
    • (2010) Sports Med , vol.40 , pp. 41-58
    • Enns, D.L.1    Tiidus, P.M.2
  • 64
    • 70349311253 scopus 로고    scopus 로고
    • Estrogen receptor regulates MyoD gene expression by preventing AP-1-mediated repression
    • Pedraza-Alva G, Zingg JM, Donda A, Perez-Martinez L (2009) Estrogen receptor regulates MyoD gene expression by preventing AP-1-mediated repression. Biochem Biophys Res Commun 389: 360-365.
    • (2009) Biochem Biophys Res Commun , vol.389 , pp. 360-365
    • Pedraza-Alva, G.1    Zingg, J.M.2    Donda, A.3    Perez-Martinez, L.4
  • 67
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester G (2008) Retinoic acid synthesis and signaling during early organogenesis. Cell 134: 921-931.
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 68
    • 45549091674 scopus 로고    scopus 로고
    • Retinoic acid in development: Towards an integrated view
    • Niederreither K, Dolle P (2008) Retinoic acid in development: towards an integrated view. Nat Rev Genet 9: 541-553.
    • (2008) Nat Rev Genet , vol.9 , pp. 541-553
    • Niederreither, K.1    Dolle, P.2
  • 69
    • 0026783879 scopus 로고
    • Retinoic acid induces myogenin synthesis and myogenic differentiation in the rat rhabdomyosarcoma cell line BA-Han-1C
    • Arnold HH, Gerharz CD, Gabbert HE, Salminen A (1992) Retinoic acid induces myogenin synthesis and myogenic differentiation in the rat rhabdomyosarcoma cell line BA-Han-1C. J Cell Biol 118: 877-887.
    • (1992) J Cell Biol , vol.118 , pp. 877-887
    • Arnold, H.H.1    Gerharz, C.D.2    Gabbert, H.E.3    Salminen, A.4
  • 70
    • 0027332392 scopus 로고
    • 9-cis-retinoic acid regulates the expression of the muscle determination gene Myf5
    • Carnac G, Albagli-Curiel O, Levin A, Bonnieu A (1993) 9-cis-retinoic acid regulates the expression of the muscle determination gene Myf5. Endocrinology 133: 2171-2176.
    • (1993) Endocrinology , vol.133 , pp. 2171-2176
    • Carnac, G.1    Albagli-Curiel, O.2    Levin, A.3    Bonnieu, A.4
  • 71
    • 0029069371 scopus 로고
    • Regulation of a muscle-specific transgene by retinoic acid
    • Xiao Y, Grieshammer U, Rosenthal N (1995) Regulation of a muscle-specific transgene by retinoic acid. J Cell Biol 129: 1345-1354.
    • (1995) J Cell Biol , vol.129 , pp. 1345-1354
    • Xiao, Y.1    Grieshammer, U.2    Rosenthal, N.3
  • 72
    • 70350225306 scopus 로고    scopus 로고
    • Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells
    • Zhu GH, Huang J, Bi Y, Su Y, Tang Y, et al. (2009) Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation 78: 195-204.
    • (2009) Differentiation , vol.78 , pp. 195-204
    • Zhu, G.H.1    Huang, J.2    Bi, Y.3    Su, Y.4    Tang, Y.5
  • 73
    • 0034907668 scopus 로고    scopus 로고
    • Synergistic anti-proliferative effects of vitamin D derivatives and 9-cis retinoic acid in SH-SY5Y human neuroblastoma cells
    • Stio M, Celli A, Treves C (2001) Synergistic anti-proliferative effects of vitamin D derivatives and 9-cis retinoic acid in SH-SY5Y human neuroblastoma cells. J Steroid Biochem Mol Biol 77: 213-222.
    • (2001) J Steroid Biochem Mol Biol , vol.77 , pp. 213-222
    • Stio, M.1    Celli, A.2    Treves, C.3
  • 74
    • 0036280792 scopus 로고    scopus 로고
    • Synergistic effect of vitamin D derivatives and retinoids on C2C12 skeletal muscle cells
    • Stio M, Celli A, Treves C (2002) Synergistic effect of vitamin D derivatives and retinoids on C2C12 skeletal muscle cells. IUBMB Life 53: 175-181.
    • (2002) IUBMB Life , vol.53 , pp. 175-181
    • Stio, M.1    Celli, A.2    Treves, C.3
  • 75
    • 0030910440 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1
    • Blutt SE, Allegretto EA, Pike JW, Weigel NL (1997) 1,25-dihydroxyvitamin D3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1. Endocrinology 138: 1491-1497.
    • (1997) Endocrinology , vol.138 , pp. 1491-1497
    • Blutt, S.E.1    Allegretto, E.A.2    Pike, J.W.3    Weigel, N.L.4
  • 76
    • 8344285665 scopus 로고    scopus 로고
    • 1 alpha,25-dihydroxyvitamin D3 transrepresses retinoic acid transcriptional activity via vitamin D receptor in myeloid cells
    • Bastie JN, Balitrand N, Guidez F, Guillemot I, Larghero J, et al. (2004) 1 alpha,25-dihydroxyvitamin D3 transrepresses retinoic acid transcriptional activity via vitamin D receptor in myeloid cells. Mol Endocrinol 18: 2685-2699.
    • (2004) Mol Endocrinol , vol.18 , pp. 2685-2699
    • Bastie, J.N.1    Balitrand, N.2    Guidez, F.3    Guillemot, I.4    Larghero, J.5
  • 77
    • 0026777853 scopus 로고
    • Mechanistic interrelationships between two superfamilies: The steroid/retinoid receptors and transforming growth factorbeta
    • Roberts AB, Sporn MB (1992) Mechanistic interrelationships between two superfamilies: the steroid/retinoid receptors and transforming growth factorbeta. Cancer Surv 14: 205-220.
    • (1992) Cancer Surv , vol.14 , pp. 205-220
    • Roberts, A.B.1    Sporn, M.B.2
  • 78
    • 66549093379 scopus 로고    scopus 로고
    • TGFbeta and retinoic acid intersect in immuneregulation
    • Mucida D, Cheroutre H (2007) TGFbeta and retinoic acid intersect in immuneregulation. Cell Adh Migr 1: 142-144.
    • (2007) Cell Adh Migr , vol.1 , pp. 142-144
    • Mucida, D.1    Cheroutre, H.2
  • 79
    • 30144440756 scopus 로고    scopus 로고
    • All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-beta/Smad signaling
    • Yu Z, Xing Y (2006) All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-beta/Smad signaling. Biochem Biophys Res Commun 340: 929-934.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 929-934
    • Yu, Z.1    Xing, Y.2
  • 80
    • 60549083689 scopus 로고    scopus 로고
    • Negative functional interaction of retinoic acid and TGF-beta signaling mediated by TG-interactingfactor during chondrogenesis
    • Zhang H, Li N, Tang Y, Wu W, Zhang Q, et al. (2009) Negative functional interaction of retinoic acid and TGF-beta signaling mediated by TG-interactingfactor during chondrogenesis. Cell Physiol Biochem 23: 157-164.
    • (2009) Cell Physiol Biochem , vol.23 , pp. 157-164
    • Zhang, H.1    Li, N.2    Tang, Y.3    Wu, W.4    Zhang, Q.5
  • 81
    • 0344393456 scopus 로고    scopus 로고
    • Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner
    • Pendaries V, Verrecchia F, Michel S, Mauviel A (2003) Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner. Oncogene 22: 8212-8220.
    • (2003) Oncogene , vol.22 , pp. 8212-8220
    • Pendaries, V.1    Verrecchia, F.2    Michel, S.3    Mauviel, A.4
  • 82
    • 0029262749 scopus 로고
    • Retinoic acid inhibition of transforming growth factor-beta-induced collagen production by human lung fibroblasts
    • Redlich CA, Delisser HM, Elias JA (1995) Retinoic acid inhibition of transforming growth factor-beta-induced collagen production by human lung fibroblasts. Am J Respir Cell Mol Biol 12: 287-295.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 287-295
    • Redlich, C.A.1    Delisser, H.M.2    Elias, J.A.3
  • 83
    • 0024755673 scopus 로고
    • Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis
    • Glick AB, Flanders KC, Danielpour D, Yuspa SH, Sporn MB (1989) Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regul 1: 87-97.
    • (1989) Cell Regul , vol.1 , pp. 87-97
    • Glick, A.B.1    Flanders, K.C.2    Danielpour, D.3    Yuspa, S.H.4    Sporn, M.B.5
  • 84
    • 0034630912 scopus 로고    scopus 로고
    • Retinoic acid resistance at late stages of human papillomavirus type 16-mediated transformation of human keratinocytes arises despite intact retinoid signaling and is due to a loss of sensitivity to transforming growth factor-beta
    • Borger DR, Mi Y, Geslani G, Zyzak LL, Batova A, et al. (2000) Retinoic acid resistance at late stages of human papillomavirus type 16-mediated transformation of human keratinocytes arises despite intact retinoid signaling and is due to a loss of sensitivity to transforming growth factor-beta. Virology 270: 397-407.
    • (2000) Virology , vol.270 , pp. 397-407
    • Borger, D.R.1    Mi, Y.2    Geslani, G.3    Zyzak, L.L.4    Batova, A.5
  • 85
    • 0030020288 scopus 로고    scopus 로고
    • Effects of endogenously activated transforming growth factor-beta on growth and differentiation of retinoic acidtreated HL-60 cells
    • Nunes I, Kojima S, Rifkin DB (1996) Effects of endogenously activated transforming growth factor-beta on growth and differentiation of retinoic acidtreated HL-60 cells. Cancer Res 56: 495-499.
    • (1996) Cancer Res , vol.56 , pp. 495-499
    • Nunes, I.1    Kojima, S.2    Rifkin, D.B.3
  • 86
    • 0030029703 scopus 로고    scopus 로고
    • Induction of transforming growth factor-beta autocrine activity by all-trans-retinoic acid and 1 alpha,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells
    • Danielpour D (1996) Induction of transforming growth factor-beta autocrine activity by all-trans-retinoic acid and 1 alpha,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells. J Cell Physiol 166: 231-239.
    • (1996) J Cell Physiol , vol.166 , pp. 231-239
    • Danielpour, D.1
  • 87
    • 0030810959 scopus 로고    scopus 로고
    • 9,13-di-cis- Retinoic acid induces the production of tPA and activation of latent TGF-beta via RAR alpha in a human liver stellate cell line, LI90
    • Imai S, Okuno M, Moriwaki H, Muto Y, Murakami K, et al. (1997) 9,13-di-cis- Retinoic acid induces the production of tPA and activation of latent TGF-beta via RAR alpha in a human liver stellate cell line, LI90. FEBS Lett 411: 102-106.
    • (1997) FEBS Lett , vol.411 , pp. 102-106
    • Imai, S.1    Okuno, M.2    Moriwaki, H.3    Muto, Y.4    Murakami, K.5
  • 88
    • 0027298030 scopus 로고
    • Mechanism of retinoid-induced activation of latent transforming growth factor-beta in bovine endothelial cells
    • Kojima S, Rifkin DB (1993) Mechanism of retinoid-induced activation of latent transforming growth factor-beta in bovine endothelial cells. J Cell Physiol 155: 323-332.
    • (1993) J Cell Physiol , vol.155 , pp. 323-332
    • Kojima, S.1    Rifkin, D.B.2
  • 89
    • 0037448691 scopus 로고    scopus 로고
    • Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells
    • La P, Morgan TA, Sykes SM, Mao H, Schnepp RW, et al. (2003) Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells. Oncogene 22: 198-210.
    • (2003) Oncogene , vol.22 , pp. 198-210
    • La, P.1    Morgan, T.A.2    Sykes, S.M.3    Mao, H.4    Schnepp, R.W.5
  • 90
    • 0037438639 scopus 로고    scopus 로고
    • Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells
    • Cao Z, Flanders KC, Bertolette D, Lyakh LA, Wurthner JU, et al. (2003) Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells. Blood 101: 498-507.
    • (2003) Blood , vol.101 , pp. 498-507
    • Cao, Z.1    Flanders, K.C.2    Bertolette, D.3    Lyakh, L.A.4    Wurthner, J.U.5
  • 93
    • 72049106099 scopus 로고    scopus 로고
    • Neuromuscular adverse effects associated with systemic retinoid dermatotherapy: Monitoring and treatment algorithm for clinicians
    • Chroni E, Monastirli A, Tsambaos D (2010) Neuromuscular adverse effects associated with systemic retinoid dermatotherapy: monitoring and treatment algorithm for clinicians. Drug Saf 33: 25-34.
    • (2010) Drug Saf , vol.33 , pp. 25-34
    • Chroni, E.1    Monastirli, A.2    Tsambaos, D.3
  • 94
    • 45549088781 scopus 로고    scopus 로고
    • Systemic retinoids in chemoprevention of onmelanoma skin cancer
    • Lens M, Medenica L (2008) Systemic retinoids in chemoprevention of onmelanoma skin cancer. Expert Opin Pharmacother 9: 1363-1374.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 1363-1374
    • Lens, M.1    Medenica, L.2
  • 96
    • 0345735908 scopus 로고    scopus 로고
    • Topical and systemic retinoid therapy for cutaneous T-cell lymphoma
    • Kempf W, Kettelhack N, Duvic M, Burg G (2003) Topical and systemic retinoid therapy for cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 17: 1405-1419.
    • (2003) Hematol Oncol Clin North Am , vol.17 , pp. 1405-1419
    • Kempf, W.1    Kettelhack, N.2    Duvic, M.3    Burg, G.4
  • 97
    • 0346099399 scopus 로고    scopus 로고
    • Retinoids: Therapeutic applications and mechanisms of action in cutaneous T-cell lymphoma
    • Zhang C, Duvic M (2003) Retinoids: therapeutic applications and mechanisms of action in cutaneous T-cell lymphoma. Dermatol Ther 16: 322-330.
    • (2003) Dermatol Ther , vol.16 , pp. 322-330
    • Zhang, C.1    Duvic, M.2


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