Therapy of thyroid carcinoma with the histone deacetylase inhibitor MS-275

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 37, Issue 12, 2010, Pages 2286-2297

  Altmann, Annette ^a   Eisenhut, Michael ^b   Bauder Wüst, Ulrike ^b   Markert, Annette ^a   Askoxylakis, Vasileios ^a   Hess Stumpp, Holger ^c   Haberkorn, Uwe ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c Research Laboratories   (Germany)

Author keywords

Apoptosis; Histone deacetylase inhibitor; Iodide uptake; p21CIP WAF1 expression; Thyroid carcinoma

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; 3 METHYLGLUCOSE; CARBON 14; CYCLIN DEPENDENT KINASE INHIBITOR 1; IODIDE; LIPOCORTIN 5; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PROPIDIUM IODIDE; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL DEATH; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PROTEIN EXPRESSION; RAT; THYROID CARCINOMA; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CELL LINE, TUMOR; FEMALE; HISTONE DEACETYLASE INHIBITORS; HUMANS; MALE; PYRIDINES; RATS; THYROID NEOPLASMS; TREATMENT OUTCOME;

EID: 78649774178     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-010-1573-3     Document Type: Article

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