Role of Ras-related C3 botulinum toxin substrate 2 (Rac2), NADPH oxidase and reactive oxygen species in diallyl disulphide-induced apoptosis of human leukaemia HL-60 cells

Clinical and Experimental Pharmacology and Physiology

Volumn 37, Issue 12, 2010, Pages 1147-1153

  Yi, Lan ^a   Ji, Xiao Xia ^a   Tan, Hui ^a   Lin, Min ^a   Tang, Yi ^a   Wen, Ling ^a   Ma, Yan Hua ^a   Su, Qi ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Diallyl disulphide; Leukaemia; NADPH oxidase; Rac2; Reactive oxygen species

Indexed keywords

CASPASE 3; DIALLYL DISULFIDE; MYC PROTEIN; RAC2 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; DNA FRAGMENTATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION;

ALLYL COMPOUNDS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; DISULFIDES; DNA FRAGMENTATION; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUKEMIA, MYELOID, ACUTE; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-MYC; RAC GTP-BINDING PROTEINS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 78649757590     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05444.x     Document Type: Article

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