The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium

American Journal of Respiratory Cell and Molecular Biology

Volumn 43, Issue 6, 2010, Pages 692-702

  Barlow, Peter G ^a   Beaumont, Paula E ^a   Cosseau, Celine ^b   Mackellar, Annie ^a   Wilkinson, Thomas S ^c   Hancock, Robert E W ^b   Haslett, Chris ^a   Govan, John R W ^d   Simpson, A John ^a   Davidson, Donald J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c SWANSEA UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Antimicrobial peptide; Apoptosis; Cationic host defense peptide; Innate immunity; Pseudomonas

Indexed keywords

CASPASE 3; CASPASE 9; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYTOCHROME C;

APOPTOSIS; ARTICLE; CELL DEATH; CELL INTERACTION; CELL MEMBRANE DEPOLARIZATION; DRUG POTENTIATION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; LUNG CLEARANCE; NONHUMAN; OUTCOME ASSESSMENT; PSEUDOMONAS AERUGINOSA; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; UPREGULATION;

ANTIMICROBIAL CATIONIC PEPTIDES; APOPTOSIS; BACTERIAL PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BRONCHI; CASPASES; CELL COMMUNICATION; CYTOCHROMES C; DNA FRAGMENTATION; ENDOCYTOSIS; ENZYME ACTIVATION; EPITHELIAL CELLS; EPITHELIUM; FIMBRIAE, BACTERIAL; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 78649736596     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0250OC     Document Type: Article

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