메뉴 건너뛰기




Volumn 15, Issue 4, 2010, Pages 551-563

Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes

Author keywords

Extracellular matrix; Heart failure; Leptin; Obesity

Indexed keywords

COLLAGEN; GELATINASE A; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROCOLLAGEN; PROCOLLAGEN TYPE 1; PROCOLLAGEN TYPE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

EID: 78649708487     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-010-0027-z     Document Type: Article
Times cited : (46)

References (35)
  • 1
    • 15044351753 scopus 로고    scopus 로고
    • Cardiac remodeling and failure: From molecules to man Part II
    • Fedak, P., Verma, S., Weisel, R. D. and Li, R. K. Cardiac remodeling and failure: From molecules to man Part II. Cardiovasc. Pathol. 14 (2005) 49-60.
    • (2005) Cardiovasc. Pathol. , vol.14 , pp. 49-60
    • Fedak, P.1    Verma, S.2    Weisel, R.D.3    Li, R.K.4
  • 3
    • 13844312743 scopus 로고    scopus 로고
    • The cardiac fibroblast: therapeutic target in myocardial remodeling and failure
    • Brown, R., Ambler, S. K., Mitchell, M. D. and Long, C. S. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu. Rev. Pharmacol. Toxicol. 45 (2005) 657-687.
    • (2005) Annu. Rev. Pharmacol. Toxicol. , vol.45 , pp. 657-687
    • Brown, R.1    Ambler, S.K.2    Mitchell, M.D.3    Long, C.S.4
  • 6
    • 0026020191 scopus 로고
    • In vivo collagen turnover during development of thyroxine-induced left ventricular hypertrophy
    • Karim, M., Ferguson, A. G., Wakim, B. T. and Samarel, A. M. In vivo collagen turnover during development of thyroxine-induced left ventricular hypertrophy. Am. J. Physiol. Lung Cell. Mol. Physiol. 260 (1991) C316-C326.
    • (1991) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.260 , pp. 316-326
    • Karim, M.1    Ferguson, A.G.2    Wakim, B.T.3    Samarel, A.M.4
  • 7
    • 0028827534 scopus 로고
    • Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss
    • Alpert, M., Lambert, C. R., Panayioutu, H., Terry, B. E., Cohen, M. V., Massey, C. V., Hashimi, M. W. and Mukerji, V. Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss. Am. J. Cardiol. 76 (1995) 1194-1197.
    • (1995) Am. J. Cardiol. , vol.76 , pp. 1194-1197
    • Alpert, M.1    Lambert, C.R.2    Panayioutu, H.3    Terry, B.E.4    Cohen, M.V.5    Massey, C.V.6    Hashimi, M.W.7    Mukerji, V.8
  • 8
    • 0035832045 scopus 로고    scopus 로고
    • Risk factors for congestive heart failure in US men and women: NHANES I epdiemiologic follow-up study
    • Je, H., Ogden, L. G., Bazzano, L. A., Vupputure, S., Loria, C. and Whelton, P. K. Risk factors for congestive heart failure in US men and women: NHANES I epdiemiologic follow-up study. Arch. Intern. Med. 161 (2001) 996-1002.
    • (2001) Arch. Intern. Med. , vol.161 , pp. 996-1002
    • Je, H.1    Ogden, L.G.2    Bazzano, L.A.3    Vupputure, S.4    Loria, C.5    Whelton, P.K.6
  • 13
    • 31344444358 scopus 로고    scopus 로고
    • Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular cardiomyocytes
    • Madani, S., de Girolamo, S., Munoz, D. M., Li, R. K. and Sweeney, G. Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular cardiomyocytes. Cardiovasc. Res. 69 (2006) 716-725.
    • (2006) Cardiovasc. Res. , vol.69 , pp. 716-725
    • Madani, S.1    de Girolamo, S.2    Munoz, D.M.3    Li, R.K.4    Sweeney, G.5
  • 14
    • 33748130863 scopus 로고    scopus 로고
    • Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes
    • Zeidan, A., Javadov, S. and Karmazyn, M. Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes. Cardiovasc. Res. 72 (2006) 101-111.
    • (2006) Cardiovasc. Res. , vol.72 , pp. 101-111
    • Zeidan, A.1    Javadov, S.2    Karmazyn, M.3
  • 15
    • 34548091302 scopus 로고    scopus 로고
    • Actin cytoskeleton dynamics promotes leptin-induced vascular smooth muscle hypertrophy via RhoA/ROCK- and phosphatidylinositol 3-kinase/protein kinase B-dependent pathways
    • Zeidan, A., Paylor, B., Steinhoff, K. J., Javadov, S., Rajapurohitam, V., Chakrabarti, S. and Karmazyn, M. Actin cytoskeleton dynamics promotes leptin-induced vascular smooth muscle hypertrophy via RhoA/ROCK- and phosphatidylinositol 3-kinase/protein kinase B-dependent pathways. J. Pharmacol. Exper. Ther. 322 (2007) 1110-1116.
    • (2007) J. Pharmacol. Exper. Ther. , vol.322 , pp. 1110-1116
    • Zeidan, A.1    Paylor, B.2    Steinhoff, K.J.3    Javadov, S.4    Rajapurohitam, V.5    Chakrabarti, S.6    Karmazyn, M.7
  • 16
    • 42749090245 scopus 로고    scopus 로고
    • Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts
    • Schram, K., Wong, M. M., Palanivel, R., No, E. K., Dixon, I. M. and Sweeney G. Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts. J. Mol. Cell. Cardiol. 44 (2008) 874-881.
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 874-881
    • Schram, K.1    Wong, M.M.2    Palanivel, R.3    No, E.K.4    Dixon, I.M.5    Sweeney, G.6
  • 17
    • 49849103205 scopus 로고    scopus 로고
    • A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart
    • Purdham, D., Rajapurohitam, V., Zeidan, A., Huang, C., Gross, G. J. and Karmazyn, M. A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart. Am. J. Physiol. Heart Circ. Physiol. 295 (2008) H441-446.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.295 , pp. 441-446
    • Purdham, D.1    Rajapurohitam, V.2    Zeidan, A.3    Huang, C.4    Gross, G.J.5    Karmazyn, M.6
  • 18
    • 0036000280 scopus 로고    scopus 로고
    • Leptin signaling
    • Sweeney, G. Leptin signaling. Cell. Signal. 14 (2002) 655-663.
    • (2002) Cell. Signal. , vol.14 , pp. 655-663
    • Sweeney, G.1
  • 19
    • 38849188633 scopus 로고    scopus 로고
    • Leptin-induced cardiomyocyte hypertrophy involves selective calveolae and RhoA/ROCK-dependent p38 MAPK translocation to nuclei
    • Zeidan, A., Javadoc, S., Chakrabarti, S. and Karmazyn, M. Leptin-induced cardiomyocyte hypertrophy involves selective calveolae and RhoA/ROCK-dependent p38 MAPK translocation to nuclei. Cardiovasc. Res. 77 (2008) 64-72.
    • (2008) Cardiovasc. Res. , vol.77 , pp. 64-72
    • Zeidan, A.1    Javadoc, S.2    Chakrabarti, S.3    Karmazyn, M.4
  • 21
    • 0042018759 scopus 로고    scopus 로고
    • Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice
    • Barouch, L., Berkowitz, D. E., Harrison, R. W., O'Donnell, C. P. and Hare, J. M. Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. Circulation108 (2003) 754-759.
    • (2003) Circulation , vol.108 , pp. 754-759
    • Barouch, L.1    Berkowitz, D.E.2    Harrison, R.W.3    O'Donnell, C.P.4    Hare, J.M.5
  • 22
    • 41849131455 scopus 로고    scopus 로고
    • Decreased p110alpha catalytic activity accompanies increased myocyte apoptosis and cardiac hypertrophy in leptin deficient ob/ob mice
    • Trivedi, P., Yang, R. and Barouch, L. A. Decreased p110alpha catalytic activity accompanies increased myocyte apoptosis and cardiac hypertrophy in leptin deficient ob/ob mice. Cell Cycle7 (2008) 560-565.
    • (2008) Cell Cycle , vol.7 , pp. 560-565
    • Trivedi, P.1    Yang, R.2    Barouch, L.A.3
  • 24
    • 70350662888 scopus 로고    scopus 로고
    • Leptin and endothelin-1 mediated increased extracellular matrix protein production and cardiomyocyte hypertrophy in diabetic heart disease
    • Majumdar, P., Chen, S., George, B., Sen, S. Karmazyn, M. and Chakrabarti, S. Leptin and endothelin-1 mediated increased extracellular matrix protein production and cardiomyocyte hypertrophy in diabetic heart disease. Diabetes Metab. Res. Rev. 25 (2009) 452-463.
    • (2009) Diabetes Metab. Res. Rev. , vol.25 , pp. 452-463
    • Majumdar, P.1    Chen, S.2    George, B.3    Sen, S.4    Karmazyn, M.5    Chakrabarti, S.6
  • 25
    • 33745148603 scopus 로고    scopus 로고
    • Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease
    • Powell, B., Redifeld, M. M., Bybee, K. A., Freeman, W. K. and Rihal, C. S. Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease. Am. J. Cardiol. 98 (2006) 116-120.
    • (2006) Am. J. Cardiol. , vol.98 , pp. 116-120
    • Powell, B.1    Redifeld, M.M.2    Bybee, K.A.3    Freeman, W.K.4    Rihal, C.S.5
  • 27
    • 0035433660 scopus 로고    scopus 로고
    • Advanced glycation endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts
    • Daoud, S., Schinzel, R., Neumann, A., Loske, C., Fraccarollo, D., Diez, C. and Simm, A. Advanced glycation endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts. Mol. Med. 7 (2001) 543-551.
    • (2001) Mol. Med. , vol.7 , pp. 543-551
    • Daoud, S.1    Schinzel, R.2    Neumann, A.3    Loske, C.4    Fraccarollo, D.5    Diez, C.6    Simm, A.7
  • 28
    • 35748974863 scopus 로고    scopus 로고
    • Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function
    • Spinale, F. Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol. Rev. 87 (2007) 1285-1342.
    • (2007) Physiol. Rev. , vol.87 , pp. 1285-1342
    • Spinale, F.1
  • 29
    • 0035973147 scopus 로고    scopus 로고
    • Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
    • Park, H., Kwon, H. M., Lim, H. J., Hong, B. K., Lee, J. Y., Park, B. E., Jang, Y., Cho, S. Y. and Kim, H. S. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exper. Mol. Med. 33 (2001) 95-102.
    • (2001) Exper. Mol. Med. , vol.33 , pp. 95-102
    • Park, H.1    Kwon, H.M.2    Lim, H.J.3    Hong, B.K.4    Lee, J.Y.5    Park, B.E.6    Jang, Y.7    Cho, S.Y.8    Kim, H.S.9
  • 30
    • 34248401646 scopus 로고    scopus 로고
    • TGF-beta-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells
    • Kim, E. S., Sohn, Y. M. and Moon, A. TGF-beta-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells. Cancer Lett. 252 (2007) 147-156.
    • (2007) Cancer Lett. , vol.252 , pp. 147-156
    • Kim, E.S.1    Sohn, Y.M.2    Moon, A.3
  • 32
    • 0038644530 scopus 로고    scopus 로고
    • Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stelate cells
    • Saxena, N., Saliba, G., Floyd, J. J. and Anania, F. A. Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stelate cells. J. Cell. Biochem. 89 (2003) 311-320.
    • (2003) J. Cell. Biochem. , vol.89 , pp. 311-320
    • Saxena, N.1    Saliba, G.2    Floyd, J.J.3    Anania, F.A.4
  • 34
    • 0028587567 scopus 로고
    • Nonsynchronouse changes in myocardial collagen mRNA and protein during aging: effect of DOCA-salt hypertension
    • Besse, S., Robert, V., Assayag, P., Delcayre, C. and Swynghedauw, B. Nonsynchronouse changes in myocardial collagen mRNA and protein during aging: effect of DOCA-salt hypertension. AJP Heart Circ. Physiol. 267 (1994) H2237-H2244.
    • (1994) AJP Heart Circ. Physiol. , vol.267 , pp. 2237-2244
    • Besse, S.1    Robert, V.2    Assayag, P.3    Delcayre, C.4    Swynghedauw, B.5
  • 35
    • 0030013679 scopus 로고    scopus 로고
    • Relationship between insulin sensitivity and plasma leptin concentrations in lean and obese men
    • Segal, K. R., Landt, M. and Klein, S. Relationship between insulin sensitivity and plasma leptin concentrations in lean and obese men. Diabetes45 (1996) 988-991.
    • (1996) Diabetes , vol.45 , pp. 988-991
    • Segal, K.R.1    Landt, M.2    Klein, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.