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Volumn 403, Issue 1, 2010, Pages 30-35

Heme controls the regulation of protein tyrosine kinases Jak2 and Src

Author keywords

Heme; Heme regulation; Jak2; Phosphorylation; Src; Tyrosine kinase

Indexed keywords

HEME; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE KINASE;

EID: 78649704465     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.101     Document Type: Article
Times cited : (40)

References (45)
  • 1
    • 0042203565 scopus 로고    scopus 로고
    • SH2 and PTB domains in tyrosine kinase signaling
    • Schlessinger J., Lemmon M.A. SH2 and PTB domains in tyrosine kinase signaling. Sci. STKE 2003, RE12.
    • (2003) Sci. STKE
    • Schlessinger, J.1    Lemmon, M.A.2
  • 2
    • 33646847329 scopus 로고    scopus 로고
    • Cell signalling: growth factors and tyrosine kinase receptors
    • Perona R. Cell signalling: growth factors and tyrosine kinase receptors. Clin. Transl. Oncol. 2006, 8:77-82.
    • (2006) Clin. Transl. Oncol. , vol.8 , pp. 77-82
    • Perona, R.1
  • 3
    • 33646358721 scopus 로고    scopus 로고
    • Structural and functional diversity of adaptor proteins involved in tyrosine kinase signalling
    • Csiszar A. Structural and functional diversity of adaptor proteins involved in tyrosine kinase signalling. Bioessays 2006, 28:465-479.
    • (2006) Bioessays , vol.28 , pp. 465-479
    • Csiszar, A.1
  • 4
    • 70649096122 scopus 로고    scopus 로고
    • SH2 domains: modulators of nonreceptor tyrosine kinase activity
    • Filippakopoulos P., Muller S., Knapp S. SH2 domains: modulators of nonreceptor tyrosine kinase activity. Curr. Opin. Struct. Biol. 2009, 19:643-649.
    • (2009) Curr. Opin. Struct. Biol. , vol.19 , pp. 643-649
    • Filippakopoulos, P.1    Muller, S.2    Knapp, S.3
  • 5
    • 66549103238 scopus 로고    scopus 로고
    • Protein tyrosine kinase, syk: a key player in phagocytic cells
    • Tohyama Y., Yamamura H. Protein tyrosine kinase, syk: a key player in phagocytic cells. J. Biochem. 2009, 145:267-273.
    • (2009) J. Biochem. , vol.145 , pp. 267-273
    • Tohyama, Y.1    Yamamura, H.2
  • 6
    • 61849130484 scopus 로고    scopus 로고
    • The tyrosine kinase network regulating mast cell activation
    • Gilfillan A.M., Rivera J. The tyrosine kinase network regulating mast cell activation. Immunol. Rev. 2009, 228:149-169.
    • (2009) Immunol. Rev. , vol.228 , pp. 149-169
    • Gilfillan, A.M.1    Rivera, J.2
  • 7
    • 77952887713 scopus 로고    scopus 로고
    • The SYK tyrosine kinase: a crucial player in diverse biological functions
    • Mocsai A., Ruland J., Tybulewicz V.L. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat. Rev. Immunol. 2010, 10:387-402.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 387-402
    • Mocsai, A.1    Ruland, J.2    Tybulewicz, V.L.3
  • 8
    • 68449093415 scopus 로고    scopus 로고
    • Exploring Rak tyrosine kinase function in breast cancer
    • Yim E.K., Siwko S., Lin S.Y. Exploring Rak tyrosine kinase function in breast cancer. Cell Cycle 2009, 8:2360-2364.
    • (2009) Cell Cycle , vol.8 , pp. 2360-2364
    • Yim, E.K.1    Siwko, S.2    Lin, S.Y.3
  • 9
    • 77956154092 scopus 로고    scopus 로고
    • Receptor tyrosine kinase alterations in AML - biology and therapy
    • Stirewalt D.L., Meshinchi S. Receptor tyrosine kinase alterations in AML - biology and therapy. Cancer Treat Res. 2009, 145:85-108.
    • (2009) Cancer Treat Res. , vol.145 , pp. 85-108
    • Stirewalt, D.L.1    Meshinchi, S.2
  • 10
    • 46749115181 scopus 로고    scopus 로고
    • Met-related receptor tyrosine kinase Ron in tumor growth and metastasis
    • Wagh P.K., Peace B.E., Waltz S.E. Met-related receptor tyrosine kinase Ron in tumor growth and metastasis. Adv. Cancer Res. 2008, 100:1-33.
    • (2008) Adv. Cancer Res. , vol.100 , pp. 1-33
    • Wagh, P.K.1    Peace, B.E.2    Waltz, S.E.3
  • 11
    • 39649116928 scopus 로고    scopus 로고
    • EGFR tyrosine kinase inhibitors in lung cancer: an evolving story
    • Sequist L.V., Lynch T.J. EGFR tyrosine kinase inhibitors in lung cancer: an evolving story. Annu. Rev. Med. 2008, 59:429-442.
    • (2008) Annu. Rev. Med. , vol.59 , pp. 429-442
    • Sequist, L.V.1    Lynch, T.J.2
  • 12
    • 47949106116 scopus 로고    scopus 로고
    • Activated c-Abl tyrosine kinase in malignant solid tumors
    • Lin J., Arlinghaus R. Activated c-Abl tyrosine kinase in malignant solid tumors. Oncogene 2008, 27:4385-4391.
    • (2008) Oncogene , vol.27 , pp. 4385-4391
    • Lin, J.1    Arlinghaus, R.2
  • 13
    • 75749103348 scopus 로고    scopus 로고
    • Src signaling in cancer invasion
    • Guarino M. Src signaling in cancer invasion. J. Cell Physiol. 2010, 223:14-26.
    • (2010) J. Cell Physiol. , vol.223 , pp. 14-26
    • Guarino, M.1
  • 14
    • 36248973171 scopus 로고    scopus 로고
    • The role of Src in prostate cancer
    • Fizazi K. The role of Src in prostate cancer. Ann. Oncol. 2007, 18:1765-1773.
    • (2007) Ann. Oncol. , vol.18 , pp. 1765-1773
    • Fizazi, K.1
  • 15
    • 34447104040 scopus 로고    scopus 로고
    • Src kinase signaling in leukaemia
    • Li S. Src kinase signaling in leukaemia. Int. J. Biochem. Cell Biol. 2007, 39:1483-1488.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 1483-1488
    • Li, S.1
  • 18
    • 32144453842 scopus 로고    scopus 로고
    • JAK/STAT signal transduction: regulators and implication in hematological malignancies
    • Valentino L., Pierre J. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem. Pharmacol. 2006, 71:713-721.
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 713-721
    • Valentino, L.1    Pierre, J.2
  • 20
    • 33747453769 scopus 로고    scopus 로고
    • Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases
    • Mense S.M., Zhang L. Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases. Cell Res. 2006, 16:681-692.
    • (2006) Cell Res. , vol.16 , pp. 681-692
    • Mense, S.M.1    Zhang, L.2
  • 23
    • 0028821439 scopus 로고
    • Heme binds to a short sequence that serves a regulatory function in diverse proteins
    • Zhang L., Guarente L. Heme binds to a short sequence that serves a regulatory function in diverse proteins. EMBO J. 1995, 14:313-320.
    • (1995) EMBO J. , vol.14 , pp. 313-320
    • Zhang, L.1    Guarente, L.2
  • 24
    • 34547948422 scopus 로고    scopus 로고
    • Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure
    • Hira S., Tomita T., Matsui T., Igarashi K., Ikeda-Saito M. Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure. IUBMB Life 2007, 59:542-551.
    • (2007) IUBMB Life , vol.59 , pp. 542-551
    • Hira, S.1    Tomita, T.2    Matsui, T.3    Igarashi, K.4    Ikeda-Saito, M.5
  • 25
    • 51249094266 scopus 로고    scopus 로고
    • Haem-regulated eIF2alpha kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency
    • Liu S., Bhattacharya S., Han A., Suragani R.N., Zhao W., Fry R.C., Chen J.J. Haem-regulated eIF2alpha kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency. Br. J. Haematol. 2008, 143:129-137.
    • (2008) Br. J. Haematol. , vol.143 , pp. 129-137
    • Liu, S.1    Bhattacharya, S.2    Han, A.3    Suragani, R.N.4    Zhao, W.5    Fry, R.C.6    Chen, J.J.7
  • 26
    • 24344444080 scopus 로고    scopus 로고
    • Interdomain interactions regulate the activation of the heme-regulated eIF 2 alpha kinase
    • Yun B.G., Matts J.A., Matts R.L. Interdomain interactions regulate the activation of the heme-regulated eIF 2 alpha kinase. Biochim. Biophys. Acta 2005, 1725:174-181.
    • (2005) Biochim. Biophys. Acta , vol.1725 , pp. 174-181
    • Yun, B.G.1    Matts, J.A.2    Matts, R.L.3
  • 27
    • 49649105752 scopus 로고    scopus 로고
    • Elucidation of the heme binding site of heme-regulated eukaryotic initiation factor 2alpha kinase and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins
    • Igarashi J., Murase M., Iizuka A., Pichierri F., Martinkova M., Shimizu T. Elucidation of the heme binding site of heme-regulated eukaryotic initiation factor 2alpha kinase and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins. J. Biol. Chem. 2008, 283:18782-18791.
    • (2008) J. Biol. Chem. , vol.283 , pp. 18782-18791
    • Igarashi, J.1    Murase, M.2    Iizuka, A.3    Pichierri, F.4    Martinkova, M.5    Shimizu, T.6
  • 29
    • 1242340434 scopus 로고    scopus 로고
    • Heme controls the expression of cell cycle regulators and cell growth in HeLa cells
    • Ye W., Zhang L. Heme controls the expression of cell cycle regulators and cell growth in HeLa cells. Biochem. Biophys. Res. Commun. 2004, 315:546-554.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 546-554
    • Ye, W.1    Zhang, L.2
  • 30
    • 0036741718 scopus 로고    scopus 로고
    • Heme deficiency interferes with the Ras-mitogen-activated protein kinase signaling pathway and expression of a subset of neuronal genes
    • Zhu Y., Hon T., Ye W., Zhang L. Heme deficiency interferes with the Ras-mitogen-activated protein kinase signaling pathway and expression of a subset of neuronal genes. Cell Growth Differ. 2002, 13:431-439.
    • (2002) Cell Growth Differ. , vol.13 , pp. 431-439
    • Zhu, Y.1    Hon, T.2    Ye, W.3    Zhang, L.4
  • 31
    • 0033049803 scopus 로고    scopus 로고
    • A new class of repression modules is critical for heme regulation of the yeast transcriptional activator Hap1
    • Hach A., Hon T., Zhang L. A new class of repression modules is critical for heme regulation of the yeast transcriptional activator Hap1. Mol. Cell. Biol. 1999, 19:4324-4333.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4324-4333
    • Hach, A.1    Hon, T.2    Zhang, L.3
  • 32
    • 0033873749 scopus 로고    scopus 로고
    • Functional analysis of heme regulatory elements of the transcriptional activator Hap1
    • Hon T., Hach A., Lee H.C., Cheng T., Zhang L. Functional analysis of heme regulatory elements of the transcriptional activator Hap1. Biochem. Biophys. Res. Commun. 2000, 273:584-591.
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 584-591
    • Hon, T.1    Hach, A.2    Lee, H.C.3    Cheng, T.4    Zhang, L.5
  • 33
    • 20444427541 scopus 로고    scopus 로고
    • Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death
    • Sengupta A., Hon T., Zhang L. Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death. Brain Res. Mol. Brain Res. 2005, 137:23-30.
    • (2005) Brain Res. Mol. Brain Res. , vol.137 , pp. 23-30
    • Sengupta, A.1    Hon, T.2    Zhang, L.3
  • 35
    • 0033614468 scopus 로고    scopus 로고
    • Heme initiates changes in the expression of a wide array of genes during the early erythroid differentiation stage
    • Zhu Y., Hon T., Zhang L. Heme initiates changes in the expression of a wide array of genes during the early erythroid differentiation stage. Biochem. Biophys. Res. Commun. 1999, 258:87-93.
    • (1999) Biochem. Biophys. Res. Commun. , vol.258 , pp. 87-93
    • Zhu, Y.1    Hon, T.2    Zhang, L.3
  • 36
    • 0036263356 scopus 로고    scopus 로고
    • An examination of heme action in gene expression: heme and heme deficiency affect the expression of diverse genes in erythroid k562 and neuronal PC12 cells
    • Zhu Y., Lee H.C., Zhang L. An examination of heme action in gene expression: heme and heme deficiency affect the expression of diverse genes in erythroid k562 and neuronal PC12 cells. DNA Cell Biol. 2002, 21:333-346.
    • (2002) DNA Cell Biol. , vol.21 , pp. 333-346
    • Zhu, Y.1    Lee, H.C.2    Zhang, L.3
  • 37
    • 2942635307 scopus 로고    scopus 로고
    • Heme deficiency causes apoptosis but does not increase ROS generation in HeLa cells
    • Ye W., Zhang L. Heme deficiency causes apoptosis but does not increase ROS generation in HeLa cells. Biochem. Biophys. Res. Commun. 2004, 319:1065-1071.
    • (2004) Biochem. Biophys. Res. Commun. , vol.319 , pp. 1065-1071
    • Ye, W.1    Zhang, L.2
  • 38
    • 77952299611 scopus 로고    scopus 로고
    • The Src, Syk, and Tec family kinases: distinct types of molecular switches
    • Bradshaw J.M. The Src, Syk, and Tec family kinases: distinct types of molecular switches. Cell Signal. 2010, 22:1175-1184.
    • (2010) Cell Signal. , vol.22 , pp. 1175-1184
    • Bradshaw, J.M.1
  • 39
    • 0030953469 scopus 로고    scopus 로고
    • Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
    • Feng J., Witthuhn B.A., Matsuda T., Kohlhuber F., Kerr I.M., Ihle J.N. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Mol. Cell. Biol. 1997, 17:2497-2501.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2497-2501
    • Feng, J.1    Witthuhn, B.A.2    Matsuda, T.3    Kohlhuber, F.4    Kerr, I.M.5    Ihle, J.N.6
  • 40
    • 70350440089 scopus 로고    scopus 로고
    • JAK redux: a second look at the regulation and role of JAKs in the heart
    • Kurdi M., Booz G.W. JAK redux: a second look at the regulation and role of JAKs in the heart. Am. J. Physiol. Heart Circ. Physiol. 2009, 297:H1545-H1556.
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.297
    • Kurdi, M.1    Booz, G.W.2
  • 41
    • 33744493616 scopus 로고    scopus 로고
    • Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects
    • Tsiftsoglou A.S., Tsamadou A.I., Papadopoulou L.C. Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects. Pharmacol Ther. 2006, 111:327-345.
    • (2006) Pharmacol Ther. , vol.111 , pp. 327-345
    • Tsiftsoglou, A.S.1    Tsamadou, A.I.2    Papadopoulou, L.C.3
  • 42
    • 0032729833 scopus 로고    scopus 로고
    • Molecular mechanism of heme signaling in yeast: the transcriptional activator Hap1 serves as the key mediator
    • Zhang L., Hach A. Molecular mechanism of heme signaling in yeast: the transcriptional activator Hap1 serves as the key mediator. Cell. Mol. Life Sci. 1999, 56:415-426.
    • (1999) Cell. Mol. Life Sci. , vol.56 , pp. 415-426
    • Zhang, L.1    Hach, A.2
  • 44
    • 44949200347 scopus 로고    scopus 로고
    • Heme-binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms
    • Kitanishi K., Igarashi J., Hayasaka K., Hikage N., Saiful I., Yamauchi S., Uchida T., Ishimori K., Shimizu T. Heme-binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms. Biochemistry 2008, 47:6157-6168.
    • (2008) Biochemistry , vol.47 , pp. 6157-6168
    • Kitanishi, K.1    Igarashi, J.2    Hayasaka, K.3    Hikage, N.4    Saiful, I.5    Yamauchi, S.6    Uchida, T.7    Ishimori, K.8    Shimizu, T.9


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