Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death

Molecular Brain Research

Volumn 137, Issue 1-2, 2005, Pages 23-30

  Sengupta, Amitabha ^a   Hon, Thomas ^a   Zhang, Li ^a  

^a Mailman School of Public Health ^*  (United States)

Author keywords

Gene expression; Heme; Neuropathy; PC12; Porphyrias; Signaling pathways

Indexed keywords

ACETONE; HEME; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; NERVE GROWTH FACTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; PROTEIN SVOP; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; DNA MICROARRAY; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE EXPRESSION; GENETIC CODE; HEME DEFICIENCY; HEME SYNTHESIS; METABOLIC DISORDER; NERVE CELL; NONHUMAN; PHEOCHROMOCYTOMA CELL; PORPHYRIA; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPSE VESICLE;

ANIMALS; APOPTOSIS; CASPASES; CELL SURVIVAL; COLLAGEN TYPE XI; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME; HEPTANOATES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURAL CELL ADHESION MOLECULES; NEURONS; PC12 CELLS; POLY(ADP-RIBOSE) POLYMERASES; PORPHYRIAS; RATS; RNA, MESSENGER; RNA-BINDING PROTEINS; UP-REGULATION; VESICULAR TRANSPORT PROTEINS;

EID: 20444427541     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2005.02.007     Document Type: Article

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