-
1
-
-
0033620978
-
Genes differentially expressed in medulloblastoma and fetal brain
-
Michiels EM, Oussoren E, Van Groenigen M, et al. Genes differentially expressed in medulloblastoma and fetal brain. Physiol Genomics 1999;1:83-91.
-
(1999)
Physiol Genomics
, vol.1
, pp. 83-91
-
-
Michiels, E.M.1
Oussoren, E.2
Van Groenigen, M.3
-
2
-
-
13444249487
-
Genomic amplification of orthodenticle homologue 2 in medulloblastomas
-
Boon K, Eberhart CG, Riggins GJ. Genomic amplification of orthodenticle homologue 2 in medulloblastomas. Cancer Res 2005;65:703-7.
-
(2005)
Cancer Res
, vol.65
, pp. 703-707
-
-
Boon, K.1
Eberhart, C.G.2
Riggins, G.J.3
-
3
-
-
33645035911
-
OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas
-
de Haas T, Oussoren E, Grajkowska W, et al. OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas. J Neuropathol Exp Neurol 2006;65:176-86.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 176-186
-
-
De Haas, T.1
Oussoren, E.2
Grajkowska, W.3
-
4
-
-
13444279877
-
Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid
-
Di C, Liao S, Adamson DC, et al. Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Cancer Res 2005;65:919-24.
-
(2005)
Cancer Res
, vol.65
, pp. 919-924
-
-
Di, C.1
Liao, S.2
Adamson, D.C.3
-
5
-
-
0028807157
-
-/- mutants due to a defective anterior neuroectoderm specification during gastrulation
-
-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development 1995;121:3279-90.
-
(1995)
Development
, vol.121
, pp. 3279-3290
-
-
Acampora, D.1
Mazan, S.2
Lallemand, Y.3
-
6
-
-
0035069878
-
The isthmic organizer and brain regionalization
-
Martinez S. The isthmic organizer and brain regionalization. Int J Dev Biol 2001;45:367-71.
-
(2001)
Int J Dev Biol
, vol.45
, pp. 367-371
-
-
Martinez, S.1
-
7
-
-
0032993290
-
Otx1 and Otx2 activities are required for the normal development of the mouse inner ear
-
Morsli H, Tuorto F, Choo D, Postiglione MP, Simeone A, Wu DK. Otx1 and Otx2 activities are required for the normal development of the mouse inner ear. Development 1999;126:2335-43.
-
(1999)
Development
, vol.126
, pp. 2335-2343
-
-
Morsli, H.1
Tuorto, F.2
Choo, D.3
Postiglione, M.P.4
Simeone, A.5
Wu, D.K.6
-
8
-
-
33747765550
-
Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout
-
Fossat N, Chatelain G, Brun G, Lamonerie T. Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout. EMBO Rep 2006;7:824-30.
-
(2006)
EMBO Rep
, vol.7
, pp. 824-830
-
-
Fossat, N.1
Chatelain, G.2
Brun, G.3
Lamonerie, T.4
-
9
-
-
52449119078
-
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
-
Kool M, Koster J, Bunt J, et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS ONE 2008;3:e3088.
-
(2008)
PLoS ONE
, vol.3
-
-
Kool, M.1
Koster, J.2
Bunt, J.3
-
10
-
-
75149149855
-
OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas
-
Adamson DC, Shi Q, Wortham M, et al. OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. Cancer Res 2010;70:181-91.
-
(2010)
Cancer Res
, vol.70
, pp. 181-191
-
-
Adamson, D.C.1
Shi, Q.2
Wortham, M.3
-
11
-
-
33646429798
-
Gene expression analyses reveal molecular relationships among 20 regions of the human CNS
-
Roth RB, Hevezi P, Lee J, et al. Gene expression analyses reveal molecular relationships among 20 regions of the human CNS. Neurogenetics 2006;7:67-80.
-
(2006)
Neurogenetics
, vol.7
, pp. 67-80
-
-
Roth, R.B.1
Hevezi, P.2
Lee, J.3
-
12
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
Sun L, Hui AM, Su Q, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006;9:287-300.
-
(2006)
Cancer Cell
, vol.9
, pp. 287-300
-
-
Sun, L.1
Hui, A.M.2
Su, Q.3
-
13
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Saeed AI, Sharov V, White J, et al. TM4: a free, open-source system for microarray data management and analysis. Biotechniques 2003;34:374-8.
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
-
14
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
Dennis G, Jr., Sherman BT, Hosack DA, et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 2003;4:3.
-
(2003)
Genome Biol
, vol.4
, pp. 3
-
-
Dennis Jr., G.1
Sherman, B.T.2
Hosack, D.A.3
-
15
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53. Nat Genet 1992;1:45-9.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
El Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
16
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
Ren B, Robert F, Wyrick JJ, et al. Genome-wide location and function of DNA binding proteins. Science 2000;290:2306-9.
-
(2000)
Science
, vol.290
, pp. 2306-2309
-
-
Ren, B.1
Robert, F.2
Wyrick, J.J.3
-
17
-
-
33644906665
-
Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma
-
Langdon JA, Lamont JM, Scott DK, et al. Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma. Genes Chromosomes Cancer 2006;45:47-60.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 47-60
-
-
Langdon, J.A.1
Lamont, J.M.2
Scott, D.K.3
-
18
-
-
0021930508
-
Establishment of a human medulloblastoma cell line and its heterotransplantation into nude mice
-
Jacobsen PF, Jenkyn DJ, Papadimitriou JM. Establishment of a human medulloblastoma cell line and its heterotransplantation into nude mice. J Neuropathol Exp Neurol 1985;44:472-85.
-
(1985)
J Neuropathol Exp Neurol
, vol.44
, pp. 472-485
-
-
Jacobsen, P.F.1
Jenkyn, D.J.2
Papadimitriou, J.M.3
-
19
-
-
0242609163
-
Epigenetic Silencing of the HIC-1 Gene in Human Medulloblastomas
-
Waha A, Waha A, Koch A, et al. Epigenetic silencing of the HIC-1 gene in human medulloblastomas. J Neuropathol Exp Neurol 2003;62:1192-201. (Pubitemid 37413829)
-
(2003)
Journal of Neuropathology and Experimental Neurology
, vol.62
, Issue.11
, pp. 1192-1201
-
-
Waha, A.1
Waha, A.2
Koch, A.3
Meyer-Puttlitz, B.4
Weggen, S.5
Sorensen, N.6
Tonn, J.C.7
Albrecht, S.8
Goodyer, C.G.9
Berthold, F.10
Wiestler, O.D.11
Pietsch, T.12
-
20
-
-
0027290895
-
Absence of p53 mutations in childhood central nervous system primitive neuroectodermal tumors
-
Raffel C, Thomas GA, Tishler DM, Lassoff S, Allen JC. Absence of p53 mutations in childhood central nervous system primitive neuroectodermal tumors. Neurosurgery 1993;33:301-5.
-
(1993)
Neurosurgery
, vol.33
, pp. 301-305
-
-
Raffel, C.1
Thomas, G.A.2
Tishler, D.M.3
Lassoff, S.4
Allen, J.C.5
-
21
-
-
33745712849
-
The power and the promise of oncogene-induced senescence markers
-
Collado M, Serrano M. The power and the promise of oncogene-induced senescence markers. Nat Rev Cancer 2006;6:472-6.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 472-476
-
-
Collado, M.1
Serrano, M.2
-
22
-
-
42949129074
-
Many roads lead to oncogene-induced senescence
-
Courtois-Cox S, Jones SL, Cichowski K. Many roads lead to oncogene-induced senescence. Oncogene 2008;27:2801-9.
-
(2008)
Oncogene
, vol.27
, pp. 2801-2809
-
-
Courtois-Cox, S.1
Jones, S.L.2
Cichowski, K.3
-
24
-
-
44649095065
-
Unexpected pieces to the senescence puzzle
-
Cichowski K, Hahn WC. Unexpected pieces to the senescence puzzle. Cell 2008;133:958-61.
-
(2008)
Cell
, vol.133
, pp. 958-961
-
-
Cichowski, K.1
Hahn, W.C.2
-
25
-
-
75449097024
-
Oncogene-induced cellular senescence
-
Chandeck C, Mooi WJ. Oncogene-induced cellular senescence. Adv Anat Pathol 2010;17:42-8.
-
(2010)
Adv Anat Pathol
, vol.17
, pp. 42-48
-
-
Chandeck, C.1
Mooi, W.J.2
-
26
-
-
58849154235
-
Senescence-messaging secretome: SMS-ing cellular stress
-
Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer 2009;9:81-94.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 81-94
-
-
Kuilman, T.1
Peeper, D.S.2
-
27
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T, Michaloglou C, Vredeveld LC, et al. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008;133:1019-31.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
-
28
-
-
38849168162
-
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
-
Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 2008;132:363-74.
-
(2008)
Cell
, vol.132
, pp. 363-374
-
-
Wajapeyee, N.1
Serra, R.W.2
Zhu, X.3
Mahalingam, M.4
Green, M.R.5
-
29
-
-
0042698559
-
OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm
-
Acampora D, Annino A, Puelles E, Alfano I, Tuorto F, Simeone A. OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Gene Expr Patterns 2003;3:497-501.
-
(2003)
Gene Expr Patterns
, vol.3
, pp. 497-501
-
-
Acampora, D.1
Annino, A.2
Puelles, E.3
Alfano, I.4
Tuorto, F.5
Simeone, A.6
-
30
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a). Cell 1997;88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
31
-
-
0142166309
-
RAS oncogenes: The first 30 years (vol 3, pg 459, 2003)
-
Malumbres M, Barbacid M. RAS oncogenes: the first 30 years (vol 3, pg 459, 2003). Nat Rev Cancer 2003;3:708.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 708
-
-
Malumbres, M.1
Barbacid, M.2
-
32
-
-
56149126490
-
C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells
-
Zhuang D, Mannava S, Grachtchouk V, et al. C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells. Oncogene 2008;27:6623-34.
-
(2008)
Oncogene
, vol.27
, pp. 6623-6634
-
-
Zhuang, D.1
Mannava, S.2
Grachtchouk, V.3
-
33
-
-
33845970597
-
Rac1 GTPase regulates cell genomic stability and senescence
-
Debidda M, Williams DA, Zheng Y. Rac1 GTPase regulates cell genomic stability and senescence. J Biol Chem 2006;281:38519-28.
-
(2006)
J Biol Chem
, vol.281
, pp. 38519-38528
-
-
Debidda, M.1
Williams, D.A.2
Zheng, Y.3
-
34
-
-
0032192153
-
Senescence of human fibroblasts induced by oncogenic Raf
-
Zhu JY, Woods D, McMahon M, Bishop JM. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev 1998;12:2997-3007.
-
(1998)
Genes Dev
, vol.12
, pp. 2997-3007
-
-
Zhu, J.Y.1
Woods, D.2
McMahon, M.3
Bishop, J.M.4
-
35
-
-
15044351968
-
Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland
-
Lazzerini DE, Attwooll C, Pasini D, Helin K. Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland. Mol Cell Biol 2005;25:2660-72.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2660-2672
-
-
Lazzerini, D.E.1
Attwooll, C.2
Pasini, D.3
Helin, K.4
-
36
-
-
36849015753
-
Myc downregulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence
-
Mallette FA, Gaumont-Leclerc MF, Huot G, Ferbeyre G. Myc downregulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence. J Biol Chem 2007;282:34938-44.
-
(2007)
J Biol Chem
, vol.282
, pp. 34938-34944
-
-
Mallette, F.A.1
Gaumont-Leclerc, M.F.2
Huot, G.3
Ferbeyre, G.4
-
37
-
-
0033559698
-
Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells
-
Ravi RK, McMahon M, Yangang Z, et al. Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells. J Cell Biochem 1999;72:458-69.
-
(1999)
J Cell Biochem
, vol.72
, pp. 458-469
-
-
Ravi, R.K.1
McMahon, M.2
Yangang, Z.3
-
38
-
-
13944250623
-
Differential oncogenic Ras signaling and senescence in tumor cells
-
Bihani T, Mason DX, Jackson TJ, Chen SC, Boettner B, Lin AW. Differential oncogenic Ras signaling and senescence in tumor cells. Cell Cycle 2004;3:1201-7.
-
(2004)
Cell Cycle
, vol.3
, pp. 1201-1207
-
-
Bihani, T.1
Mason, D.X.2
Jackson, T.J.3
Chen, S.C.4
Boettner, B.5
Lin, A.W.6
-
39
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002;2:103-12.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
40
-
-
77949881221
-
The senescence-associated secretory phenotype: The dark side of tumor suppression
-
Coppe JP, Desprez PY, Krtolica A, Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 2010;5:99-118.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 99-118
-
-
Coppe, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
41
-
-
36048965126
-
Breaking news: High-speed race ends in arrest-how oncogenes induce senescence
-
Di Micco R, Fumagalli M. Breaking news: high-speed race ends in arrest-how oncogenes induce senescence. Trends Cell Biol 2007;17:529-36.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 529-536
-
-
Di Micco, R.1
Fumagalli, M.2
-
42
-
-
0037663490
-
Werner syndrome protein limits MYC-induced cellular senescence
-
Grandori C, Wu KJ, Fernandez P, et al. Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev 2003;17:1569-74.
-
(2003)
Genes Dev
, vol.17
, pp. 1569-1574
-
-
Grandori, C.1
Wu, K.J.2
Fernandez, P.3
-
43
-
-
0028172248
-
Cavenee WK. p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma
-
Adesina AM, Nalbantoglu J, Cavenee WK. p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 1994;54:5649-51.
-
(1994)
Cancer Res
, vol.54
, pp. 5649-5651
-
-
Adesina, A.M.1
Nalbantoglu, J.2
-
44
-
-
0027299875
-
P53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing
-
Badiali M, Iolascon A, Loda M, et al. p53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing. Diagn Mol Pathol 1993;2:23-8.
-
(1993)
Diagn Mol Pathol
, vol.2
, pp. 23-28
-
-
Badiali, M.1
Iolascon, A.2
Loda, M.3
-
45
-
-
0026513426
-
Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis
-
Cogen PH, Daneshvar L, Metzger AK, Duyk G, Edwards MS, Sheffield VC. Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis. Am J Hum Genet 1992;50:584-9.
-
(1992)
Am J Hum Genet
, vol.50
, pp. 584-589
-
-
Cogen, P.H.1
Daneshvar, L.2
Metzger, A.K.3
Duyk, G.4
Edwards, M.S.5
Sheffield, V.C.6
-
46
-
-
0942290729
-
Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization
-
Tong CY, Hui AB, Yin XL, et al. Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization. J Neurosurg 2004;100:187-93.
-
(2004)
J Neurosurg
, vol.100
, pp. 187-193
-
-
Tong, C.Y.1
Hui, A.B.2
Yin, X.L.3
-
47
-
-
38049074854
-
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D
-
Castellino RC, De Bortoli M, Lu X, et al. Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D. J Neurooncol 2008;86:245-56.
-
(2008)
J Neurooncol
, vol.86
, pp. 245-256
-
-
Castellino, R.C.1
De Bortoli, M.2
Lu, X.3
-
48
-
-
33644670527
-
Comprehensive genomic analysis of desmoplastic medulloblastomas: Identification of novel amplified genes and separate evaluation of the different histological components
-
Ehrbrecht A, Muller U, Wolter M, et al. Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components. J Pathol 2006;208:554-63.
-
(2006)
J Pathol
, vol.208
, pp. 554-563
-
-
Ehrbrecht, A.1
Muller, U.2
Wolter, M.3
-
49
-
-
31544450175
-
Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma
-
Mendrzyk F, Radlwimmer B, Joos S, et al. Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. J Clin Oncol 2005;23:8853-62.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8853-8862
-
-
Mendrzyk, F.1
Radlwimmer, B.2
Joos, S.3
-
50
-
-
0029897610
-
Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme
-
Rollbrocker B, Waha A, Louis DN, Wiestler OD, von Deimling A. Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathol 1996;92:70-4.
-
(1996)
Acta Neuropathol
, vol.92
, pp. 70-74
-
-
Rollbrocker, B.1
Waha, A.2
Louis, D.N.3
Wiestler, O.D.4
Von Deimling, A.5
-
51
-
-
33751075209
-
Overlay analysis of the oligonucleotide array gene expression profiles and copy number abnormalities as determined by array comparative genomic hybridization in medulloblastomas
-
DOI 10.1002/gcc.20388
-
Lo KC, Rossi MR, Burkhardt T, Pomeroy SL, Cowell JK. Overlay analysis of the oligonucleotide array gene expression profiles and copy number abnormalities as determined by array comparative genomic hybridization in medulloblastomas. Genes Chromosomes Cancer 2007;46:53-66. (Pubitemid 44772872)
-
(2007)
Genes Chromosomes and Cancer
, vol.46
, Issue.1
, pp. 53-66
-
-
Lo, K.C.1
Rossi, M.R.2
Burkhardt, T.3
Pomeroy, S.L.4
Cowell, J.K.5
-
52
-
-
33646362581
-
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
-
Thompson MC, Fuller C, Hogg TL, et al. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol 2006;24:1924-31.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1924-1931
-
-
Thompson, M.C.1
Fuller, C.2
Hogg, T.L.3
|