How cations can assist dnase i in DNA binding and hydrolysis

PLoS Computational Biology

Volumn 6, Issue 11, 2010, Pages

  Guéroult, Marc ^a,b   Picot, Daniel ^a   Abi Ghanem, Joséphine ^b   Hartmann, Brigitte ^b   Baaden, Marc ^a  

^a INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

^b INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOINFORMATICS; CONSERVATION; ELECTROSTATICS; HYDROLYSIS; MOLECULAR DYNAMICS; POSITIVE IONS;

BINDING POCKETS; CA 2+; COUNTERIONS; CRYSTALLOGRAPHIC STRUCTURE; DNA-BINDING; DNASE I; DYNAMICS SIMULATION; HYDROLYTIC MECHANISMS; ION BINDING; ION BINDING SITES;

DNA;

AMINO ACID; CALCIUM ION; DEOXYRIBONUCLEASE I; DOUBLE STRANDED DNA; MAGNESIUM ION; CALCIUM; CATION; DNA; MAGNESIUM;

ARTICLE; BINDING SITE; CALCULATION; DNA BINDING; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROLYSIS; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PROTEIN DNA INTERACTION; SIMULATION; AMINO ACID SEQUENCE; ANIMAL; CATTLE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; POISSON DISTRIBUTION; REPRODUCIBILITY; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

BOVINAE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCIUM; CATIONS; CATTLE; CRYSTALLOGRAPHY, X-RAY; DEOXYRIBONUCLEASE I; DNA; HYDROLYSIS; MAGNESIUM; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE ANNOTATION; MOLECULAR SEQUENCE DATA; POISSON DISTRIBUTION; REPRODUCIBILITY OF RESULTS; SEQUENCE ALIGNMENT;

EID: 78649649423     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1001000     Document Type: Article

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