Ca2+-dependent activity of human DNase I and its hyperactive variants

Protein Science

Volumn 8, Issue 9, 1999, Pages 1780-1788

  Pan, Clark Q ^a   Lazarus, Robert A ^a  

^a GENENTECH INC   (United States)

Author keywords

Ca2+ binding effects; DNase I; Protein DNA interactions; Site directed mutagenesis; Structure function analysis

Indexed keywords

AMINO ACID; CALCIUM ION; DEOXYRIBONUCLEASE I; DOUBLE STRANDED DNA; MAGNESIUM ION; CALCIUM; DNA; ISOENZYME;

ARTICLE; BINDING SITE; CALCIUM BINDING; CATALYSIS; ENZYME ACTIVITY; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; CELL LINE; DNA SUPERCOILING; ENZYME STABILITY; GENETICS; METABOLISM; PHYSIOLOGY; POINT MUTATION;

BINDING SITES; CALCIUM; CELL LINE; DEOXYRIBONUCLEASE I; DNA; DNA, SUPERHELICAL; ENZYME STABILITY; HUMANS; ISOENZYMES; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION;

EID: 0032586271     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.9.1780     Document Type: Article

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