Simultaneous determination of 10 mycotoxins in grain by ultra-high-performance liquid chromatography-tandem mass spectrometry using 13C15-deoxynivalenol as internal standard

Food Additives and Contaminants - Part A

Volumn 27, Issue 12, 2010, Pages 1701-1713

  Jina, P G ^a   Hanb, Z ^b   Caia, Z X ^a   Wub, Y J ^b   Rena, Y P ^a  

^a ZHEJIANG PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Cereals and grain; LC MS; Method validation; Mycotoxins; Ochratoxin a; Trichothecenes; Zearalenone

Indexed keywords

ACETONITRILE; AMMONIA; ELECTROSPRAY IONIZATION; GRAIN (AGRICULTURAL PRODUCT); MASS SPECTROMETRY;

CEREALS AND GRAINS; LC/MS; METHOD VALIDATIONS; MYCOTOXINS; OCHRATOXIN A; TRICHOTHECENES; ZEARALENONE;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

15 ACETYLVOMITOXIN; 3 ACETYLDEOXYNIVALENOL; ACETONITRILE; FUSARENON X; MONILIFORMIN; MYCOTOXIN; NIVALENOL; OCHRATOXIN; TOXIN; UNCLASSIFIED DRUG; VOMITOXIN; ZEARALANONE; ZEARALENONE;

ARTICLE; CORN; GRAIN; MASS SPECTROMETRY; PRIORITY JOURNAL; STANDARD; TOXIN ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ZEA MAYS;

EID: 78649596798     PISSN: 19440049     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/19440049.2010.517222     Document Type: Article

References (37)

1. Bascaran V, de Rojas AH, Choucino P, Delgado T. 2007. Analysis of ochratoxin A in milk after direct immunoaffinity column clean-up by high-performance liquid chromatography with fluorescence detection. J Chromatogr A. 1167(1):95-101.
2. Berthiller F, Schuhmacher R, Buttinger G, Krska R. 2005. Rapid simultaneous determination of major type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 1062(2):209-216.
3. Bogialli S, Curini R, Di Corcia A, Nazzari M, Samperi R. 2003. A liquid chromatography-mass spectrometry assay for analyzing sulfonamide antibacterials in cattle and fish muscle tissues. Anal Chem. 75(8):1798-1804.
4. Bottalico A. 1998. Fusarium disease of cereals: species complex and related mycotoxin profiles in Europe. J Plant Pathol. 80(2):85-103.
5. Briones-Reyes D, Gomez-Martinez L, Cueva-Rolon R. 2007. Zearalenone contamination in corn for human consumption in the state of Tlaxcala, Mexico. Food Chem. 100(2):693-698.
6. Castillo MA, Montes R, Navarro A, Segarra R, Cuesta G, Hernandez E. 2008. Occurrence of deoxynivalenol and nivalenol in Spanish corn-based food products. J Food Compos Anal. 21(5):423-427.
7. Cavaliere C, D'Ascenzo G, Foglia P, Pastorini E, Samperi R, Lagana A. 2005. Determination of type B trichothecenes and macrocyclic lactone mycotoxins in field contaminated maize. Food Chem. 92(3):559-568.
8. Chinese Commission. 2005. Commission Regulation (GB) No. 2761/2005 of 1 October 2005 amending Regulations (GB) No. 9676/2003, No. 2761/1981, No. 16329/1996 and No. 14974/2003 as maximum levels of mycotoxins in foods. GuoBiao. L 53:1-2.
9. Cohen H, Lapointe M. 1982. Capillary gas-liquid chromatographic determination of vomitoxin in cereal grains. J Assoc Off Anal Chem. 65(6):1429-1434.
10. Cunha SC, Faria MA, Fernandes JO. 2009. Determination of patulin in apple and quince products by GC-MS using 13C5-7 patulin as internal standard. Food Chem. 115(1):352-359.
11. Di Mavungu DJ, Monbaliu S, Scippo ML, Maghuin-Rogister G, Schneider YJ, Larondelle Y, Callebaut A, Robbens J, Van Peteghem C, De Saeger S. 2009. LC-MS/ MS multi-analyte method for mycotoxin determination in food supplements. Food Addit Contam. 26(6):885-895.
12. D'Mello JPF, Placinta CM, Macdonald AMC. 1999. Fusarium mycotoxins: a review of global implications for animal health, welfare and productivity. Anim Feed Sci Technol. 80(3/4):183-205.
13. Eppley RM, Trucksess MW, Nesheim S, Thorpe CW, Pohland AE. 1986. Thin-Layer chromatographic method for determination of deoxynivalenol in wheat. Collaborative study. J Assoc Off Anal Chem. 69(1):37-40.
14. European Commission. 2002. Commission Regulation No. 472/2002, 2002. Off J Eur Union. L75:18-20.
15. European Commission. 2005. Commission Regulation (EC) No. 856/2005 of 6 June 2005 amending Regulation (EC) No. 466/2001 as regards Fusarium toxins (Text with EEA relevance). Off J Eur Union. L143:3-8.
16. European Commission. 2007. Commission Regulation (EC) No. 1126/2007 of 28 September 2007 amending Regulation (EC) No. 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Off J Eur Union. L255:14-17.
17. Gilbert J, Sharman M, Patel S, Boenke A, Wagstaffe PJ. 1992. Deoxynivalenol in wheat and maize flour reference materials. 2. Preparation and certification. Food Addit Contam. 9(2):119-135.
18. González-Osnaya L, Soriano JM, Molt JC, Maňes J. 2008. Simple liquid chromatography assay for analyzing ochratoxin A in bovine milk. Food Chem. 108(1):272-276.
19. Grabarkiewicz-Szczesna J, Kostecki M, Golinski P, Kiecana I. 2001. Fusariotoxins in kernels of winter wheat cultivars field samples collected during (1993) in Poland. Nahrung-Food. 45(1):28-30.
20. Häubl G, Berthiller F, Krska R, Schuhmacher R. 2006. Suitability of a fully 13C isotope labeled internal standard for the determination of the mycotoxin deoxynivalenol by LC-MS/MS without clean up. Anal Bioanal Chem. 384(3):692-696.
21. Kabak B. 2009. Ochratoxin A in cereal-derived products in Turkey: occurrence and exposure assessment. Food Chem Toxicol. 47(2):348-352.
22. Kebarle P, Tang L. 1993. From ions in solution to ions in the gas phase - the mechanism of electrospray mass spectrometry. Anal Chem. 65(22):972A-986A.
23. Klötzel M, Gutsche B, Lauber U, Humpf HU. 2005. Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry. J Agric Food Chem. 53(23):8904-8910.
24. Klötzel M, Lauber U, Humpf HU. 2006. A new solid phase extraction clean-up method for the determination of 12 type A and B trichothecenes in cereals and cereal-based food by LC-MS/MS. Mol Nutr Food Res. 50(3):261-269.
25. Krska R, Josephs R. 2001. The state-of-the-art in the analysis of estrogenic mycotoxins in cereals. Fresenius J Anal Chem. 369(6):469-476.
26. Krska R, Baumgartner S, Josephs R. 2001. The state-of-theart in the analysis of type-A and -B trichothecene mycotoxins in cereals. Fresenius J Anal Chem. 371(3):285-299.
27. Kuiper-Goodman T. 1995. Mycotoxins: risk assessment and legislation. Toxicol Lett. 82-83(7):853-859.
28. Maragos CM, Appell M. 2007. Capillary electrophoresis of the mycotoxin zearalenone using cyclodextrin-enhanced fluorescence. J Chromatogr A. 1143(1-2):252-257.
29. Mateo JJ, Mateo R, Hinojo MJ, Llorens A, Jimenez M. 2002. Liquid chromatographic determination of toxigenic secondary metabolites produced by Fusarium strains. J Chromatogr A. 955(2):245-256.
30. Mubatanhema W, Moss MO, Frank MJ, Wilson DM. 1999. Prevalence of Fusarium species of the Liseola section on Zimbabwean corn and their ability to produce the mycotoxinszearalenone, moniliformin and fumonisin B1. Mycopathologia. 148(3):157-163.
31. Omurtag GZ, Yazicioglu D. 2001. Occurrence of T-2 toxin in processed cereals and pulses in Turkey determined by HPLC and TLC. Food Addit Contam. 18(9):844-849.
32. Razzazi-Fazeli E, Rabus B, Cecon B, Bohm J. 2002. Simultaneous quantification of A-trichothecene mycotoxins in grains using liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry. J Chromatogr A. 968(1/2):129-142.
33. Ren Y, Zhang Y, Shao S, Cai Z, Feng L, Pan H, Wang Z. 2007. Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 1143(1/2):48-64.
34. Schollenberger M, Lauber U, Jara HT, Suchy S, Drochner W, Muller HM. 1998. Determination of eight trichothecenes by gas chromatography-mass spectrometry after sample clean-up by a two-stage solid-phase extraction. J Chromatogr A. 815(1):123-132.
35. Solovey MM, Somoza C, Cano G, Pacin A, Resnik S. 1999. A survey of fumonisins, deoxynivalenol, zearalenone and aflatoxins contamination in corn-based food products in Argentina. Food Addit Contam. 16(8):325-329.
36. Spanjer MC, Rensen PM, Scholten JM. 2008. LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. Food Addit Contam. 25(4):472-489.
37. Sulyok M, Berthiller F, Krska R, Schuhmacher R. 2006. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize. Rapid Commun Mass Spectrom. 20(18):2649-2659.