Fish oil prevents breast cancer cell metastasis to bone

Biochemical and Biophysical Research Communications

Volumn 402, Issue 4, 2010, Pages 602-607

  Mandal, Chandi Charan ^a   Ghosh Choudhury, Triparna ^a   Yoneda, Toshi ^c   Choudhury, Goutam Ghosh ^b,c   Ghosh Choudhury, Nandini ^a,b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

DHA; EPA; Fish oil diet; Osteolytic metastasis

Indexed keywords

DOCOSAHEXAENOIC ACID; HERMES ANTIGEN; ICOSAPENTAENOIC ACID; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER CELL CULTURE; CANCER INVASION; CANCER STEM CELL; CELL MIGRATION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD44; BONE NEOPLASMS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DIET; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; FEMALE; FISH OILS; HUMANS; MICE; NEOPLASM METASTASIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA; MUS;

EID: 78649446287     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.063     Document Type: Article

References (34)

1. Lands W.E., Hamazaki T., Yamazaki K., Okuyama H., Sakai K., Goto Y., Hubbard V.S. Changing dietary patterns. Am. J. Clin. Nutr. 1990, 51:991-993.
2. Chajes V., Sattler W., Stranzl A., Kostner G.M. Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. Breast Cancer Res. Treat. 1995, 34:199-212.
3. Rose D.P., Connolly J.M. Omega-3 fatty acids as cancer chemopreventive agents. Pharmacol. Ther. 1999, 83:217-244.
4. Schley P.D., Jijon H.B., Robinson L.E., Field C.J. Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells. Breast Cancer Res. Treat. 2005, 92:187-195.
5. Nguyen D.X., Bos P.D., Massague J. Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 2009, 9:274-284.
6. Klein C.A. The systemic progression of human cancer: a focus on the individual disseminated cancer cell--the unit of selection. Adv. Cancer Res. 2003, 89:35-67.
7. Minna J.D., Kurie J.M., Jacks T. A big step in the study of small cell lung cancer. Cancer Cell 2003, 4:163-166.
8. Gupta G.P., Nguyen D.X., Chiang A.C., Bos P.D., Kim J.Y., Nadal C., Gomis R.R., Manova-Todorova K., Massague J. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 2007, 446:765-770.
9. Padua D., Zhang X.H., Wang Q., Nadal C., Gerald W.L., Gomis R.R., Massague J. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 2008, 133:66-77.
10. Rose D.P., Connolly J.M., Rayburn J., Coleman M. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. J. Natl. Cancer Inst. 1995, 87:587-592.
11. Ghosh-Choudhury T., Mandal C.C., Woodruff K., St Clair P., Fernandes G., Choudhury G.G., Ghosh-Choudhury N. Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth. Breast Cancer Res. Treat. 2009, 118:213-228.
12. Rose D.P., Connolly J.M., Coleman M. Effect of omega-3 fatty acids on the progression of metastases after the surgical excision of human breast cancer cell solid tumors growing in nude mice. Clin. Cancer Res. 1996, 2:1751-1756.
13. Mundy G.R. Metastasis to bone: causes consequences and therapeutic opportunities. Nat. Rev. Cancer. 2002, 2:584-593.
14. Kopp H.G., Avecilla S.T., Hooper A.T., Rafii S. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda) 2005, 20:349-356.
15. Godar S., Ince T.A., Bell G.W., Feldser D., Donaher J.L., Bergh J., Liu A., Miu K., Watnick R.S., Reinhardt F., McAllister S.S., Jacks T., Weinberg R.A. Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 2008, 134:62-73.
16. Hiraga T., Williams P.J., Mundy G.R., Yoneda T. The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases. Cancer Res. 2001, 61:4418-4424.
17. Bange J., Prechtl D., Cheburkin Y., Specht K., Harbeck N., Schmitt M., Knyazeva T., Muller S., Gartner S., Sures I., Wang H., Imyanitov E., Haring H.U., Knayzev P., Iacobelli S., Hofler H., Ullrich A. Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele. Cancer Res. 2002, 62:840-847.
18. Mandal C.C., Ghosh Choudhury G., Ghosh-Choudhury N. Phosphatidylinositol 3 kinase/Akt signal relay cooperates with smad in bone morphogenetic protein-2-induced colony stimulating factor-1 (CSF-1) expression and osteoclast differentiation. Endocrinology 2009, 150:4989-4998.
19. Ghosh Choudhury G., Abboud H.E. Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFbeta-induced fibronectin expression in mesangial cells. Cell. Signal 2004, 16:31-41.
20. Ghosh-Choudhury N., Abboud S.L., Nishimura R., Celeste A., Mahimainathan L., Choudhury G.G. Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad- dependent BMP-2 gene transcription. J. Biol. Chem. 2002, 277:33361-33368.
21. Ghosh-Choudhury N., Mandal C.C., Choudhury G.G. Statin-induced Ras Activation Integrates the Phosphatidylinositol 3-Kinase Signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. J. Biol. Chem. 2007, 282:4983-4993.
22. Ghosh-Choudhury N., Singha P.K., Woodruff K., St Clair P., Bsoul S., Werner S.L., Choudhury G.G. Concerted action of Smad and CREB-binding protein regulates bone morphogenetic protein-2-stimulated osteoblastic colony-stimulating factor-1 expression. J. Biol. Chem. 2006, 281:20160-20170.
23. Ghosh-Choudhury N., Mandal C.C., Ghosh-Choudhury N., Ghosh Choudhury G. Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth. Cell. Signal 2010, 22:749-758.
24. Ouhtit A., Abd Elmageed Z.Y., Abdraboh M.E., Lioe T.F., Raj M.H. In vivo evidence for the role of CD44s in promoting breast cancer metastasis to the liver. Am. J. Pathol. 2007, 171:2033-2039.
25. Weber G.F., Bronson R.T., Ilagan J., Cantor H., Schmits R., Mak T.W. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res. 2002, 62:2281-2286.
26. Auvinen P., Tammi R., Tammi M., Johansson R., Kosma V.M. Expression of CD 44 s, CD 44 v 3 and CD 44 v 6 in benign and malignant breast lesions: correlation and colocalization with hyaluronan. Histopathology 2005, 47:420-428.
27. Gotte M., Yip G.W. Heparanase, hyaluronan, and CD44 in cancers: a breast carcinoma perspective. Cancer Res. 2006, 66:10233-10237.
28. Guise T.A., Yin J.J., Taylor S.D., Kumagai Y., Dallas M., Boyce B.F., Yoneda T., Mundy G.R. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J. Clin. Invest. 1996, 98:1544-1549.
29. Li F., Tiede B., Massague J., Kang Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Res. 2007, 17:3-14.
30. Uchino M., Kojima H., Wada K., Imada M., Onoda F., Satofuka H., Utsugi T., Murakami Y. Nuclear beta-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells. BMC Cancer 2010, 10:414-430.
31. Sheridan C., Kishimoto H., Fuchs R.K., Mehrotra S., Bhat-Nakshatri P., Turner C.H., Goulet R., Badve S., Nakshatri H. CD44+/CD24-breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res. 2006, 8:R59.
32. Nakamura H., Hiraga T., Ninomiya T., Hosoya A., Fujisaki N., Yoneda T., Ozawa H. Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice. J. Bone Miner. Metab. 2008, 26:642-647.
33. Ponta H., Sherman L., Herrlich P.A. CD44: from adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 2003, 4:33-45.
34. Hill A., McFarlane S., Johnston P.G., Waugh D.J. The emerging role of CD44 in regulating skeletal micrometastasis. Cancer Lett. 2006, 237:1-9.