Genomic profiling of Tumor Necrosis Factor alpha (TNF-α) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-α signaling and increased severity of 1918 pandemic influenza virus infection

Journal of Virology

Volumn 84, Issue 24, 2010, Pages 12576-12588

  Belisle, Sarah E ^a   Tisoncik, Jennifer R ^a   Korth, Marcus J ^a   Carter, Victoria S ^a   Proll, Sean C ^a   Swayne, David E ^b   Pantin Jackwood, Mary ^b   Tumpey, Terrence M ^c   Katze, Michael G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MOTION; DENDRITIC CELL; DISEASE SEVERITY; GENE DISRUPTION; GENE EXPRESSION PROFILING; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; INNATE IMMUNITY; INOCULATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PANDEMIC INFLUENZA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR GENE; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL COMMUNICATION; CELL MOVEMENT; DENDRITIC CELLS; GENE EXPRESSION PROFILING; INFLUENZA A VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORTHOMYXOVIRIDAE INFECTIONS; PANDEMICS; RECEPTORS, INTERLEUKIN-1 TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

MUS; ORTHOMYXOVIRIDAE;

EID: 78649404732     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01310-10     Document Type: Article

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