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Volumn 14, Issue 9, 2010, Pages 2257-2263

Individualized medicine 2010

Author keywords

Array analyses; Disease prognosis; Disease risk; Genome wide association studies; Genomics; Individualized medicine; Metabolomics; MicroRNA; Prediction of therapeutic efficacy; Proteomics; Transcriptomics

Indexed keywords

GENE EXPRESSION PROFILING; GENETICS; GENOMICS; HAPLOTYPE; HUMAN; MUTATION; NEOPLASM; PERSONALIZED MEDICINE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 78649364942     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01155.x     Document Type: Review
Times cited : (2)

References (80)
  • 2
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature. 2001; 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 3
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science. 2001; 291: 1304-51.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 4
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracilbased adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracilbased adjuvant chemotherapy for colon cancer. N Engl J Med. 2003; 349: 247-57.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 5
    • 0037010411 scopus 로고    scopus 로고
    • DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study
    • Barratt PL, Seymour MT, Stenning SP, et al. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study. Lancet. 2002; 360: 1381-91.
    • (2002) Lancet , vol.360 , pp. 1381-1391
    • Barratt, P.L.1    Seymour, M.T.2    Stenning, S.P.3
  • 6
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • Roth AD, Tejpar S, Delorenzi M, et al. (2010) Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol. 2010; 28: 466-74.
    • (2010) J Clin Oncol , vol.2010 , Issue.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3
  • 7
    • 0141731323 scopus 로고    scopus 로고
    • Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer
    • Fallik D, Borrini F, Boige V, et al. Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer. Cancer Res. 2003; 63: 5738-44.
    • (2003) Cancer Res , vol.63 , pp. 5738-5744
    • Fallik, D.1    Borrini, F.2    Boige, V.3
  • 8
    • 45749127481 scopus 로고    scopus 로고
    • Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial
    • Braun MS, Richman SD, Quirke P, et al. Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. J Clin Oncol. 2008; 26: 2690-8.
    • (2008) J Clin Oncol , vol.26 , pp. 2690-2698
    • Braun, M.S.1    Richman, S.D.2    Quirke, P.3
  • 9
    • 40849147041 scopus 로고    scopus 로고
    • EGFR antagonists in cancer treatment
    • Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med. 2008; 358: 1160-74.
    • (2008) N Engl J Med , vol.358 , pp. 1160-1174
    • Ciardiello, F.1    Tortora, G.2
  • 10
    • 54949110541 scopus 로고    scopus 로고
    • Targeting EGFR in colorectal cancer
    • Messersmith WA, Ahnen DJ. Targeting EGFR in colorectal cancer. N Engl J Med. 2008; 359: 1834-6.
    • (2008) N Engl J Med , vol.359 , pp. 1834-1836
    • Messersmith, W.A.1    Ahnen, D.J.2
  • 11
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008; 359: 1757-65.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 12
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med. 2009; 360: 563-72.
    • (2009) N Engl J Med , vol.360 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3
  • 13
    • 59749089432 scopus 로고    scopus 로고
    • Targeted therapy for advanced colorectal cancer-more is not always better
    • Mayer RJ. Targeted therapy for advanced colorectal cancer-more is not always better. N Engl J Med. 2009; 360: 623-5.
    • (2009) N Engl J Med , vol.360 , pp. 623-625
    • Mayer, R.J.1
  • 14
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009; 360: 1408-17.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 15
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol. 2008; 26: 5705-12.
    • (2008) J Clin Oncol , vol.26 , pp. 5705-5712
    • Di Nicolantonio, F.1    Martini, M.2    Molinari, F.3
  • 16
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009; 361: 947-57.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 17
    • 67650290547 scopus 로고    scopus 로고
    • Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3
    • Van Cutsem E, Labianca R, Bodoky G, et al. Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3. J Clin Oncol. 2009; 27: 3117-25.
    • (2009) J Clin Oncol , vol.27 , pp. 3117-3125
    • Van Cutsem, E.1    Labianca, R.2    Bodoky, G.3
  • 18
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    • Van Cutsem E, Vervenne WL, Bennouna J, et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. J Clin Oncol. 2009; 27: 2231-7.
    • (2009) J Clin Oncol , vol.27 , pp. 2231-2237
    • Van Cutsem, E.1    Vervenne, W.L.2    Bennouna, J.3
  • 19
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M. Pancreatic cancer. N Engl J Med. 2010; 362: 1605-17.
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 21
    • 70349966196 scopus 로고    scopus 로고
    • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
    • Thomas DL, Thio CL, Martin MP, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature. 2009; 461: 798-801.
    • (2009) Nature , vol.461 , pp. 798-801
    • Thomas, D.L.1    Thio, C.L.2    Martin, M.P.3
  • 22
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferonalpha and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G, et al. (2009) IL28B is associated with response to chronic hepatitis C interferonalpha and ribavirin therapy. Nat Genet. 2009; 41: 1100-4.
    • (2009) Nat Genet. 2009 , vol.41 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3
  • 23
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet. 2009; 41: 1105-9.
    • (2009) Nat Genet , vol.41 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 24
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study
    • e1331-7
    • Rauch A, Kutalik Z, Descombes P, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology. 2010; 138: 1338-45, e1331-7.
    • (2010) Gastroenterology , vol.138 , pp. 1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3
  • 25
    • 77949773445 scopus 로고    scopus 로고
    • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
    • Fellay J, Thompson AJ, Ge D, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature. 2010; 464: 405-8.
    • (2010) Nature , vol.464 , pp. 405-408
    • Fellay, J.1    Thompson, A.J.2    Ge, D.3
  • 26
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Project. Nature. 2003; 426: 789-96.
    • (2003) Nature , vol.426 , pp. 789-796
  • 27
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • A haplotype map of the human genome. Nature. 2005; 437: 1299-320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 28
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • Manolio TA, Brooks LD, Collins FS. A HapMap harvest of insights into the genetics of common disease. J Clin Invest. 2008; 118: 1590-605.
    • (2008) J Clin Invest , vol.118 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 29
    • 66349121862 scopus 로고    scopus 로고
    • The HapMap and genome-wide association studies in diagnosis and therapy
    • Manolio TA, Collins FS. The HapMap and genome-wide association studies in diagnosis and therapy. Annu Rev Med. 2009; 60: 443-56.
    • (2009) Annu Rev Med , vol.60 , pp. 443-456
    • Manolio, T.A.1    Collins, F.S.2
  • 30
    • 34547623750 scopus 로고    scopus 로고
    • Genomewide association analysis of coronary artery disease
    • Samani NJ, Erdmann J, Hall AS, et al. Genomewide association analysis of coronary artery disease. N Engl J Med. 2007; 357: 443-53.
    • (2007) N Engl J Med , vol.357 , pp. 443-453
    • Samani, N.J.1    Erdmann, J.2    Hall, A.S.3
  • 31
    • 34547629039 scopus 로고    scopus 로고
    • Scanning the genome for coronary risk
    • Rosenzweig A. Scanning the genome for coronary risk. N Engl J Med. 2007; 357: 497-9.
    • (2007) N Engl J Med , vol.357 , pp. 497-499
    • Rosenzweig, A.1
  • 32
    • 34547926806 scopus 로고    scopus 로고
    • A genetic risk factor for periodic limb movements in sleep
    • Stefansson H, Rye DB, Hicks A, et al. A genetic risk factor for periodic limb movements in sleep. N Engl J Med. 2007; 357: 639-47.
    • (2007) N Engl J Med , vol.357 , pp. 639-647
    • Stefansson, H.1    Rye, D.B.2    Hicks, A.3
  • 33
    • 34548083742 scopus 로고    scopus 로고
    • Whole-genome analysis of sporadic amyotrophic lateral sclerosis
    • Dunckley T, Huentelman MJ, Craig DW, et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. N Engl J Med. 2007; 357: 775-88.
    • (2007) N Engl J Med , vol.357 , pp. 775-788
    • Dunckley, T.1    Huentelman, M.J.2    Craig, D.W.3
  • 34
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genomewide study
    • Hafler DA, Compston A, Sawcer S, et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med. 2007; 357: 851-62.
    • (2007) N Engl J Med , vol.357 , pp. 851-862
    • Hafler, D.A.1    Compston, A.2    Sawcer, S.3
  • 35
    • 77950202777 scopus 로고    scopus 로고
    • Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease
    • Petersen KF, Dufour S, Hariri A, et al. Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. N Engl J Med. 2010; 362: 1082-9.
    • (2010) N Engl J Med , vol.362 , pp. 1082-1089
    • Petersen, K.F.1    Dufour, S.2    Hariri, A.3
  • 36
    • 38049059334 scopus 로고    scopus 로고
    • Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis
    • Tanabe KK, Lemoine A, Finkelstein DM, et al. Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis. JAMA. 2008; 299: 53-60.
    • (2008) JAMA , vol.299 , pp. 53-60
    • Tanabe, K.K.1    Lemoine, A.2    Finkelstein, D.M.3
  • 37
    • 77949578084 scopus 로고    scopus 로고
    • Performance of common genetic variants in breast-cancer risk models
    • Wacholder S, Hartge P, Prentice R, et al. Performance of common genetic variants in breast-cancer risk models. N Engl J Med. 2010; 362: 986-93.
    • (2010) N Engl J Med , vol.362 , pp. 986-993
    • Wacholder, S.1    Hartge, P.2    Prentice, R.3
  • 38
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • Goldstein DB. Common genetic variation and human traits. N Engl J Med. 2009; 360: 1696-8.
    • (2009) N Engl J Med , vol.360 , pp. 1696-1698
    • Goldstein, D.B.1
  • 39
    • 65949099120 scopus 로고    scopus 로고
    • Genetic risk prediction - are we there yet?
    • Kraft P, Hunter DJ. Genetic risk prediction - are we there yet? N Engl J Med. 2009; 360: 1701-3.
    • (2009) N Engl J Med , vol.360 , pp. 1701-1703
    • Kraft, P.1    Hunter, D.J.2
  • 40
    • 7444253428 scopus 로고    scopus 로고
    • Systems biology and new technologies enable predictive and preventative medicine
    • Hood L, Heath JR, Phelps ME, et al. Systems biology and new technologies enable predictive and preventative medicine. Science. 2004; 306: 640-3.
    • (2004) Science , vol.306 , pp. 640-643
    • Hood, L.1    Heath, J.R.2    Phelps, M.E.3
  • 41
    • 77951902009 scopus 로고    scopus 로고
    • Using genetic diagnosis to determine individual therapeutic utility
    • Caskey CT. Using genetic diagnosis to determine individual therapeutic utility. Annu Rev Med. 2010; 61: 1-15.
    • (2010) Annu Rev Med , vol.61 , pp. 1-15
    • Caskey, C.T.1
  • 42
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000; 403: 503-11.
    • (2000) Nature. 2000 , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 43
    • 57149089307 scopus 로고    scopus 로고
    • Stromal gene signatures in large-B-cell lymphomas
    • Lenz G, Wright G, Dave SS, et al. Stromal gene signatures in large-B-cell lymphomas. N Engl J Med. 2008; 359: 2313-23.
    • (2008) N Engl J Med , vol.359 , pp. 2313-2323
    • Lenz, G.1    Wright, G.2    Dave, S.S.3
  • 44
    • 77949345555 scopus 로고    scopus 로고
    • Tumorassociated macrophages and survival in classic Hodgkin's lymphoma
    • Steidl C, Lee T, Shah SP, et al. Tumorassociated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med. 2010. 362: 875-85.
    • (2010) N Engl J Med , vol.362 , pp. 875-885
    • Steidl, C.1    Lee, T.2    Shah, S.P.3
  • 45
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature. 2006; 439: 353-7.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3
  • 46
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002; 347: 1999-2009.
    • (2002) N Engl J Med , vol.347 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3
  • 47
    • 0038244058 scopus 로고    scopus 로고
    • Gene expression predictors of breast cancer outcomes
    • Huang E, Cheng SH, Dressman H, et al. Gene expression predictors of breast cancer outcomes. Lancet. 2003; 361: 1590-6.
    • (2003) Lancet , vol.361 , pp. 1590-1596
    • Huang, E.1    Cheng, S.H.2    Dressman, H.3
  • 48
    • 0042125511 scopus 로고    scopus 로고
    • Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
    • Chang JC, Wooten EC, Tsimelzon A, et al. Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet. 2003; 362: 362-9.
    • (2003) Lancet , vol.362 , pp. 362-369
    • Chang, J.C.1    Wooten, E.C.2    Tsimelzon, A.3
  • 49
    • 33646681444 scopus 로고    scopus 로고
    • HER2 and responsiveness of breast cancer to adjuvant chemotherapy
    • Pritchard KI, Shepherd LE, O'Malley FP, et al. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med. 2006; 354: 2103-11.
    • (2006) N Engl J Med , vol.354 , pp. 2103-2111
    • Pritchard, K.I.1    Shepherd, L.E.2    O'Malley, F.P.3
  • 50
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • Liu R, Wang X, Chen GY, et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med. 2007; 356: 217-26.
    • (2007) N Engl J Med , vol.356 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3
  • 51
    • 33846459466 scopus 로고    scopus 로고
    • Sorting out breast-cancer gene signatures
    • Massague J. Sorting out breast-cancer gene signatures. N Engl J Med. 2007; 356: 294-7.
    • (2007) N Engl J Med , vol.356 , pp. 294-297
    • Massague, J.1
  • 52
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med. 2009; 360: 790-800.
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 53
    • 0041735992 scopus 로고    scopus 로고
    • Proteomic patterns of tumour subsets in non-small-cell lung cancer
    • Yanagisawa K, Shyr Y, Xu BJ, et al. Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet. 2003; 362: 433-9.
    • (2003) Lancet , vol.362 , pp. 433-439
    • Yanagisawa, K.1    Shyr, Y.2    Xu, B.J.3
  • 54
    • 33846011470 scopus 로고    scopus 로고
    • A fivegene signature and clinical outcome in non-small-cell lung cancer
    • Chen HY, Yu SL, Chen CH, et al. A fivegene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med. 2007; 356: 11-20.
    • (2007) N Engl J Med , vol.356 , pp. 11-20
    • Chen, H.Y.1    Yu, S.L.2    Chen, C.H.3
  • 55
    • 33846031169 scopus 로고    scopus 로고
    • Molecular signatures of lung cancer-toward personalized therapy
    • Herbst RS, Lippman SM. Molecular signatures of lung cancer-toward personalized therapy. N Engl J Med. 2007; 356: 76-8.
    • (2007) N Engl J Med , vol.356 , pp. 76-78
    • Herbst, R.S.1    Lippman, S.M.2
  • 56
    • 67649446283 scopus 로고    scopus 로고
    • Metabolic profiling identifies lung tumor responsiveness to erlotinib
    • Fan TW, Lane AN, Higashi RM, et al. Metabolic profiling identifies lung tumor responsiveness to erlotinib. Exp Mol Pathol. 2009; 87: 83-6.
    • (2009) Exp Mol Pathol , vol.87 , pp. 83-86
    • Fan, T.W.1    Lane, A.N.2    Higashi, R.M.3
  • 57
    • 60149091657 scopus 로고    scopus 로고
    • Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
    • Sreekumar A, Poisson LM, Rajendiran TM, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009; 2009; 457: 910-4.
    • (2009) Nature , vol.2009 , Issue.457 , pp. 910-914
    • Sreekumar, A.1    Poisson, L.M.2    Rajendiran, T.M.3
  • 58
    • 77951826127 scopus 로고    scopus 로고
    • Retrospective analysis of prostate cancer recurrence potential with tissue metabolomic profiles
    • Maxeiner A, Adkins CB, Zhang Y, et al. Retrospective analysis of prostate cancer recurrence potential with tissue metabolomic profiles. Prostate. 2010. 70: 710-7.
    • (2010) Prostate , vol.70 , pp. 710-717
    • Maxeiner, A.1    Adkins, C.B.2    Zhang, Y.3
  • 59
    • 75349084543 scopus 로고    scopus 로고
    • Risk of HCC: genetic heterogeneity and complex genetics
    • Dragani TA. Risk of HCC: genetic heterogeneity and complex genetics. J Hepatol. 2010; 52: 252-7.
    • (2010) J Hepatol , vol.52 , pp. 252-257
    • Dragani, T.A.1
  • 60
    • 75349110931 scopus 로고    scopus 로고
    • Liver cancer: from molecular pathogenesis to new therapies: summary of the EASL single topic conference
    • Dufour JF, Johnson P. Liver cancer: from molecular pathogenesis to new therapies: summary of the EASL single topic conference. J Hepatol. 2010; 52: 296-304.
    • (2010) J Hepatol , vol.52 , pp. 296-304
    • Dufour, J.F.1    Johnson, P.2
  • 61
    • 77951915307 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: novel molecular approaches for diagnosis, prognosis, and therapy
    • Villanueva A, Minguez B, Forner A, et al. Hepatocellular carcinoma: novel molecular approaches for diagnosis, prognosis, and therapy. Annu Rev Med. 2010; 61: 317-28.
    • (2010) Annu Rev Med , vol.61 , pp. 317-328
    • Villanueva, A.1    Minguez, B.2    Forner, A.3
  • 62
    • 33644913732 scopus 로고    scopus 로고
    • Molecular prognostication of liver cancer: end of the beginning
    • Thorgeirsson SS, Lee JS, Grisham JW. Molecular prognostication of liver cancer: end of the beginning. J Hepatol. 2006 44: 798-805.
    • (2006) J Hepatol , vol.44 , pp. 798-805
    • Thorgeirsson, S.S.1    Lee, J.S.2    Grisham, J.W.3
  • 63
    • 33750613935 scopus 로고    scopus 로고
    • Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas
    • Luo JH, Ren B, Keryanov S, et al. Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas. Hepatology. 2006; 44: 1012-24.
    • (2006) Hepatology , vol.44 , pp. 1012-1024
    • Luo, J.H.1    Ren, B.2    Keryanov, S.3
  • 64
    • 33745577640 scopus 로고    scopus 로고
    • Comparative and integrative functional genomics of HCC
    • Lee JS, Thorgeirsson SS. Comparative and integrative functional genomics of HCC. Oncogene. 2006; 25: 3801-9.
    • (2006) Oncogene , vol.25 , pp. 3801-3809
    • Lee, J.S.1    Thorgeirsson, S.S.2
  • 65
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • Boyault S, Rickman DS, de Reynies A, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology. 2007; 45: 42-52.
    • (2007) Hepatology , vol.45 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    de Reynies, A.3
  • 66
    • 0037443891 scopus 로고    scopus 로고
    • Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection
    • Iizuka N, Oka M, Yamada-Okabe H, et al. Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet. 2003; 361: 923-9.
    • (2003) Lancet , vol.361 , pp. 923-929
    • Iizuka, N.1    Oka, M.2    Yamada-Okabe, H.3
  • 67
    • 70349871321 scopus 로고    scopus 로고
    • MicroRNA expression, survival, and response to interferon in liver cancer
    • Ji J, Shi J, Budhu A, et al. MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med. 2009; 361: 1437-47.
    • (2009) N Engl J Med , vol.361 , pp. 1437-1447
    • Ji, J.1    Shi, J.2    Budhu, A.3
  • 68
    • 76249128792 scopus 로고    scopus 로고
    • miR-221 overexpression contributes to liver tumorigenesis
    • Pineau P, Volinia S, McJunkin K, et al. miR-221 overexpression contributes to liver tumorigenesis. Proc Natl Acad Sci USA. 2010; 107: 264-9.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 264-269
    • Pineau, P.1    Volinia, S.2    McJunkin, K.3
  • 69
    • 77950622025 scopus 로고    scopus 로고
    • MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma
    • Yao J, Liang L, Huang S, et al. MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma. Hepatology. 2010; 51: 846-56.
    • (2010) Hepatology , vol.51 , pp. 846-856
    • Yao, J.1    Liang, L.2    Huang, S.3
  • 70
    • 77950602604 scopus 로고    scopus 로고
    • Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    • Xiong Y, Fang JH, Yun JP, et al. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology. 2010; 51: 836-45.
    • (2010) Hepatology , vol.51 , pp. 836-845
    • Xiong, Y.1    Fang, J.H.2    Yun, J.P.3
  • 71
    • 75549086735 scopus 로고    scopus 로고
    • A new NMR-based metabolomics approach for the diagnosis of biliary tract cancer
    • Wen H, Yoo SS, Kang J, et al. A new NMR-based metabolomics approach for the diagnosis of biliary tract cancer. J Hepatol. 2010; 52: 228-33.
    • (2010) J Hepatol , vol.52 , pp. 228-233
    • Wen, H.1    Yoo, S.S.2    Kang, J.3
  • 72
    • 59349098653 scopus 로고    scopus 로고
    • Regulation of the hepatitis C virus genome replication by miR-199a
    • Murakami Y, Aly HH, Tajima A, et al. Regulation of the hepatitis C virus genome replication by miR-199a. J Hepatol. 2009; 50: 453-60.
    • (2009) J Hepatol , vol.50 , pp. 453-460
    • Murakami, Y.1    Aly, H.H.2    Tajima, A.3
  • 73
    • 59349089182 scopus 로고    scopus 로고
    • Regulation of hepatitis C virus replication by microRNAs
    • Pietschmann T. Regulation of hepatitis C virus replication by microRNAs. J Hepatol. 2009; 50: 441-4.
    • (2009) J Hepatol , vol.50 , pp. 441-444
    • Pietschmann, T.1
  • 74
    • 28844464258 scopus 로고    scopus 로고
    • Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C
    • Asselah T, Bieche I, Laurendeau I, et al. Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C. Gastroenterology. 2005; 129: 2064-75.
    • (2005) Gastroenterology , vol.129 , pp. 2064-2075
    • Asselah, T.1    Bieche, I.2    Laurendeau, I.3
  • 75
    • 70350054801 scopus 로고    scopus 로고
    • A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C
    • Marcolongo M, Young B, Dal Pero F, et al. A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C. Hepatology. 2009; 50: 1038-44.
    • (2009) Hepatology , vol.50 , pp. 1038-1044
    • Marcolongo, M.1    Young, B.2    Dal Pero, F.3
  • 76
    • 60849098754 scopus 로고    scopus 로고
    • The metabonomic signature of celiac disease
    • Bertini I, Calabro A, De Carli V, et al. The metabonomic signature of celiac disease. J Proteome Res. 2009; 8: 170-7.
    • (2009) J Proteome Res , vol.8 , pp. 170-177
    • Bertini, I.1    Calabro, A.2    De Carli, V.3
  • 77
    • 77952470787 scopus 로고    scopus 로고
    • Gene-expression profiling for rejection surveillance after cardiac transplantation
    • Pham MX, Teuteberg JJ, Kfoury AG, et al. Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med. 2010; 362: 1890-900.
    • (2010) N Engl J Med , vol.362 , pp. 1890-1900
    • Pham, M.X.1    Teuteberg, J.J.2    Kfoury, A.G.3
  • 78
    • 77953151708 scopus 로고    scopus 로고
    • CISH and susceptibility to infectious diseases
    • Khor CC, Vannberg FO, Chapman SJ, et al. CISH and susceptibility to infectious diseases. N Engl J Med. 2010; 362: 2092-101.
    • (2010) N Engl J Med , vol.362 , pp. 2092-2101
    • Khor, C.C.1    Vannberg, F.O.2    Chapman, S.J.3
  • 79
    • 77951589703 scopus 로고    scopus 로고
    • Clinical assessment incorporating a personal genome
    • Ashley EA, Butte AJ, Wheeler MT, et al. Clinical assessment incorporating a personal genome. Lancet. 2010; 375: 1525-35.
    • (2010) Lancet , vol.375 , pp. 1525-1535
    • Ashley, E.A.1    Butte, A.J.2    Wheeler, M.T.3
  • 80
    • 77951547487 scopus 로고    scopus 로고
    • The personal genome-the future of personalised medicine?
    • Samani NJ, Tomaszewski M, Schunkert H. The personal genome-the future of personalised medicine? Lancet. 2010; 375: 1497-8.
    • (2010) Lancet , vol.375 , pp. 1497-1498
    • Samani, N.J.1    Tomaszewski, M.2    Schunkert, H.3


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