-
1
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M, et al: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 18:2938-2947, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
de Gramont, A.1
Figer, A.2
Seymour, M.3
-
2
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, et al: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial. Lancet 355:1041-1047, 2000
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
-
4
-
-
24944452378
-
Reporting recommendations for tumour MARKer prognostic studies (REMARK)
-
and Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics
-
McShane LM, Altman DG, Sauerbrei W, et al: and Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics: Reporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 93:387-391, 2005
-
(2005)
Br J Cancer
, vol.93
, pp. 387-391
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
-
5
-
-
0037010411
-
-
Barratt PL, Seymour MT, Stenning SP, et al: and the AXIS Collaborators: DNA markers predicting benefit from adjuvant 5-fluorouracil in colon cancer patients: A molecular study. Lancet 360:1381-1391, 2002
-
Barratt PL, Seymour MT, Stenning SP, et al: and the AXIS Collaborators: DNA markers predicting benefit from adjuvant 5-fluorouracil in colon cancer patients: A molecular study. Lancet 360:1381-1391, 2002
-
-
-
-
6
-
-
7244249977
-
Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours?
-
Grabsch H, Kerr D, Quirke P: Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours? Histopathology 45:312-334, 2004
-
(2004)
Histopathology
, vol.45
, pp. 312-334
-
-
Grabsch, H.1
Kerr, D.2
Quirke, P.3
-
7
-
-
15244362062
-
p53 abnormalities and outcomes in colorectal cancer: A systematic review
-
Munro AJ, Lain S, Lane DP: p53 abnormalities and outcomes in colorectal cancer: A systematic review. Br J Cancer 92:434-444, 2005
-
(2005)
Br J Cancer
, vol.92
, pp. 434-444
-
-
Munro, A.J.1
Lain, S.2
Lane, D.P.3
-
8
-
-
34447255724
-
Different strategies of sequential and combination chemotherapy for patients with poor-prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
-
for the FOCUS Trial Investigators and the National Cancer Res Institute Colorectal Clinical Studies Group
-
Seymour MT, Maughan TS, Ledermann JA, et al: for the FOCUS Trial Investigators and the National Cancer Res Institute Colorectal Clinical Studies Group: Different strategies of sequential and combination chemotherapy for patients with poor-prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial. Lancet 370:143-152, 2007
-
(2007)
Lancet
, vol.370
, pp. 143-152
-
-
Seymour, M.T.1
Maughan, T.S.2
Ledermann, J.A.3
-
9
-
-
0037068330
-
A 'modified de Gramont' regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer
-
Cheeseman SL, Joel SP, Chester JD, et al: A 'modified de Gramont' regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer. Br J Cancer 87:393-399, 2002
-
(2002)
Br J Cancer
, vol.87
, pp. 393-399
-
-
Cheeseman, S.L.1
Joel, S.P.2
Chester, J.D.3
-
10
-
-
0037132332
-
Phase II study of irinotecan with bolus and high dose infusional 5-FU and folinic acid (modified de Gramont) for first or second line treatment of advanced or metastatic colorectal cancer
-
Leonard P, Seymour MT, Janes R, et al: Phase II study of irinotecan with bolus and high dose infusional 5-FU and folinic acid (modified de Gramont) for first or second line treatment of advanced or metastatic colorectal cancer. Br J Cancer 87:1216-1220, 2002
-
(2002)
Br J Cancer
, vol.87
, pp. 1216-1220
-
-
Leonard, P.1
Seymour, M.T.2
Janes, R.3
-
11
-
-
0242266500
-
Modified de Gramont with oxaliplatin in the first-line treatment of advanced colorectal cancer
-
Braun MS, Adab F, Bradley C, et al: Modified de Gramont with oxaliplatin in the first-line treatment of advanced colorectal cancer. Br J Cancer 89:1155-1158, 2003
-
(2003)
Br J Cancer
, vol.89
, pp. 1155-1158
-
-
Braun, M.S.1
Adab, F.2
Bradley, C.3
-
12
-
-
0031982522
-
ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
-
Metzger R, Leichman CG, Danenberg KD, et al: ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 16:309-316, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 309-316
-
-
Metzger, R.1
Leichman, C.G.2
Danenberg, K.D.3
-
13
-
-
0029758307
-
Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity
-
McLeod HL, Keith WN: Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity. Br J Cancer 74:508-512, 1996
-
(1996)
Br J Cancer
, vol.74
, pp. 508-512
-
-
McLeod, H.L.1
Keith, W.N.2
-
14
-
-
0036722801
-
Cellular effects of CPT-11 on colon carcinoma cells: Dependence on p53 and hMLH1 status
-
Magrini R, Bhonde MR, Hanski ML, et al: Cellular effects of CPT-11 on colon carcinoma cells: Dependence on p53 and hMLH1 status. Int J Cancer 101:23-31, 2002
-
(2002)
Int J Cancer
, vol.101
, pp. 23-31
-
-
Magrini, R.1
Bhonde, M.R.2
Hanski, M.L.3
-
15
-
-
0036160987
-
O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives
-
Okamoto R, Takano H, Okamura T, et al: O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives. Jpn J Cancer Res 93:93-102, 2002
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 93-102
-
-
Okamoto, R.1
Takano, H.2
Okamura, T.3
-
16
-
-
0037108880
-
Cyclooxygenase-2 inhibition with celecoxib enhances antitumour efficacy and reduces diarrhea side effect of CPT-11
-
Trifan OC, Durham WF, Salazar VS, et al: Cyclooxygenase-2 inhibition with celecoxib enhances antitumour efficacy and reduces diarrhea side effect of CPT-11. Cancer Res 62:5778-5784, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 5778-5784
-
-
Trifan, O.C.1
Durham, W.F.2
Salazar, V.S.3
-
17
-
-
0032789079
-
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair
-
Cawkwell L, Gray S, Murgatroyd H, et al: Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut 45:409-415, 1999
-
(1999)
Gut
, vol.45
, pp. 409-415
-
-
Cawkwell, L.1
Gray, S.2
Murgatroyd, H.3
-
18
-
-
0037134707
-
Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
-
Stoehlmacher J, Park DJ, Zhang W, et al: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer J Natl Cancer Inst 94:936-942, 2002
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 936-942
-
-
Stoehlmacher, J.1
Park, D.J.2
Zhang, W.3
-
19
-
-
12144286615
-
Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan
-
Sai K, Kaniwa N, Itoda M, et al: Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan. Pharmacogenetics 13:741-757, 2003
-
(2003)
Pharmacogenetics
, vol.13
, pp. 741-757
-
-
Sai, K.1
Kaniwa, N.2
Itoda, M.3
-
20
-
-
0036731995
-
MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
-
Illmer T, Schuler US, Thiede C, et al: MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 62:4955-4962, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 4955-4962
-
-
Illmer, T.1
Schuler, U.S.2
Thiede, C.3
-
21
-
-
0037081269
-
X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance
-
Park SY, Lam W, Cheng YC: X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance. Cancer Res 62:459-465, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 459-465
-
-
Park, S.Y.1
Lam, W.2
Cheng, Y.C.3
-
22
-
-
0035174375
-
A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer
-
Stoehlmacher J, Ghaderi V, Iobal S, et al: A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. Anticancer Res 21:3075-3079, 2001
-
(2001)
Anticancer Res
, vol.21
, pp. 3075-3079
-
-
Stoehlmacher, J.1
Ghaderi, V.2
Iobal, S.3
-
23
-
-
0035893755
-
A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer
-
Park DJ, Stoehlmacher J, Zhang W, et al: A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res 61:8654-8658, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 8654-8658
-
-
Park, D.J.1
Stoehlmacher, J.2
Zhang, W.3
-
24
-
-
0242442751
-
Pharmacogenetic analysis of systemic toxicity and response after 5-fluorouracil (5FU)/CPT-11, 5FU/oxaliplatin (oxal), or CPT-11/oxal therapy for advanced colorectal cancer: Results from an intergroup trial
-
suppl; abstr 1013, 253s
-
McLeod HL, Sargent DJ, Marsh S, et al: Pharmacogenetic analysis of systemic toxicity and response after 5-fluorouracil (5FU)/CPT-11, 5FU/oxaliplatin (oxal), or CPT-11/oxal therapy for advanced colorectal cancer: Results from an intergroup trial. Proc Am Soc Clin Oncol 22:253s, 2003 (suppl; abstr 1013)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
McLeod, H.L.1
Sargent, D.J.2
Marsh, S.3
-
25
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Innocenti F, Undevia SD, Iyer L, et al: Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 22:1382-1388, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
-
26
-
-
84871470104
-
-
Richman SD, Braun MS, Adlard JW, et al: Prognostic value of thymidylate synthase expression on failure-free survival of fluorouracil-treated metastatic colorectal cancer patients. J Clin Oncol 2006 ASCO Annual Meeting Proceedings 24:543s, 2006 (suppl 18S; abstr 10011)
-
Richman SD, Braun MS, Adlard JW, et al: Prognostic value of thymidylate synthase expression on failure-free survival of fluorouracil-treated metastatic colorectal cancer patients. J Clin Oncol 2006 ASCO Annual Meeting Proceedings 24:543s, 2006 (suppl 18S; abstr 10011)
-
-
-
-
27
-
-
0037967461
-
Planning for subgroup analysis: A case study of treatment-marker interaction in metastatic colorectal cancer
-
Gönen M: Planning for subgroup analysis: A case study of treatment-marker interaction in metastatic colorectal cancer. Control Clin Trials 24:355-363, 2003
-
(2003)
Control Clin Trials
, vol.24
, pp. 355-363
-
-
Gönen, M.1
-
28
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, et al: Assessing the probability that a positive report is false: An approach for molecular epidemiology studies. J Natl Cancer Inst 96:434-442, 2004
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
-
29
-
-
0036858423
-
Topoisomerase I protein expression in primary colorectal cancer and lymph node metastases
-
Boonsong A, Curran S, McKay JA, et al: Topoisomerase I protein expression in primary colorectal cancer and lymph node metastases. Hum Pathol 33:1114-1119, 2002
-
(2002)
Hum Pathol
, vol.33
, pp. 1114-1119
-
-
Boonsong, A.1
Curran, S.2
McKay, J.A.3
-
30
-
-
3142660249
-
Topoisomerase-I, thymidylate synthase primary tumour expression and clinical efficacy of 5-FU/CPT-11 chemotherapy in advanced colorectal cancer patients
-
Paradiso A, Xu J, Mangia A, et al: Topoisomerase-I, thymidylate synthase primary tumour expression and clinical efficacy of 5-FU/CPT-11 chemotherapy in advanced colorectal cancer patients. Int J Cancer 111:252-258, 2004
-
(2004)
Int J Cancer
, vol.111
, pp. 252-258
-
-
Paradiso, A.1
Xu, J.2
Mangia, A.3
-
31
-
-
0033208192
-
Topoisomerase I inhibitors: Selectivity and cellular resistance
-
Pommier Y, Pourquier P, Urasaki Y, et al: Topoisomerase I inhibitors: Selectivity and cellular resistance. Drug Resist Updat 2:307-318, 1999
-
(1999)
Drug Resist Updat
, vol.2
, pp. 307-318
-
-
Pommier, Y.1
Pourquier, P.2
Urasaki, Y.3
-
32
-
-
2442449490
-
Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan: A preliminary study
-
Pavillard V, Charasson V, Laroche-Clary A, et al: Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan: A preliminary study. Anticancer Res 24:579-585, 2004
-
(2004)
Anticancer Res
, vol.24
, pp. 579-585
-
-
Pavillard, V.1
Charasson, V.2
Laroche-Clary, A.3
-
33
-
-
33749587322
-
Molecular determinants of irinotecan efficacy
-
Vallböhmer D, Iqbal S, Yang DY, et al: Molecular determinants of irinotecan efficacy. Int J Cancer 119:2435-2442, 2006
-
(2006)
Int J Cancer
, vol.119
, pp. 2435-2442
-
-
Vallböhmer, D.1
Iqbal, S.2
Yang, D.Y.3
-
34
-
-
11144232327
-
Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin
-
van Waardenburg RC, de Jong LA, van Eijndhoven MA, et al: Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin. J Biol Chem 279:54502-54509, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 54502-54509
-
-
van Waardenburg, R.C.1
de Jong, L.A.2
van Eijndhoven, M.A.3
-
35
-
-
0000482574
-
Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2
-
Juan CC, Hwang JL, Liu AA, et al: Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2. Proc Natl Acad Sci U S A 85:8910-8913, 1988
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 8910-8913
-
-
Juan, C.C.1
Hwang, J.L.2
Liu, A.A.3
-
36
-
-
0032911521
-
Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization
-
Korn WM, Yasutake T, Kuo WL, et al: Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization. Genes Chromosomes Cancer 25:82-90, 1999
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 82-90
-
-
Korn, W.M.1
Yasutake, T.2
Kuo, W.L.3
-
37
-
-
0035545841
-
Chromosomal aberrations in colorectal cancers and liver metastases analyzed by comparative genomic hybridization
-
Aragane H, Sakakura C, Nakanishi M, et al: Chromosomal aberrations in colorectal cancers and liver metastases analyzed by comparative genomic hybridization. Int J Cancer 94:623-629, 2001
-
(2001)
Int J Cancer
, vol.94
, pp. 623-629
-
-
Aragane, H.1
Sakakura, C.2
Nakanishi, M.3
-
38
-
-
20144366958
-
Chromosomal instability in flat adenomas and carcinomas of the colon
-
Postma C, Hermsen MA, Coffa J, et al: Chromosomal instability in flat adenomas and carcinomas of the colon. J Pathol 205:514-521, 2005
-
(2005)
J Pathol
, vol.205
, pp. 514-521
-
-
Postma, C.1
Hermsen, M.A.2
Coffa, J.3
-
39
-
-
0037440051
-
Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
-
Allegra CJ, Paik S, Colangelo LH, et al: Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 21:241-250, 2003
-
(2003)
J Clin Oncol
, vol.21
, pp. 241-250
-
-
Allegra, C.J.1
Paik, S.2
Colangelo, L.H.3
-
40
-
-
0038002279
-
Tumour microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
-
Ribic CM, Sargent DJ, Moore MJ, et al: Tumour microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349:247-257, 2003
-
(2003)
N Engl J Med
, vol.349
, pp. 247-257
-
-
Ribic, C.M.1
Sargent, D.J.2
Moore, M.J.3
-
41
-
-
34447277453
-
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial
-
Koopman M, Antonini NF, Douma J, et al: Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial. Lancet 370:135-142, 2007
-
(2007)
Lancet
, vol.370
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
-
42
-
-
43549084892
-
Capecitabine and oxaliplatin in elderly and/or frail patients with metastatic colorectal cancer: The FOCUS2 trial
-
suppl; abstr 9030, 500s
-
Seymour MT, Maughan TS, Wasan HS, et al: Capecitabine and oxaliplatin in elderly and/or frail patients with metastatic colorectal cancer: The FOCUS2 trial. J Clin Oncol 25:500s, 2007 (suppl; abstr 9030)
-
(2007)
J Clin Oncol
, vol.25
-
-
Seymour, M.T.1
Maughan, T.S.2
Wasan, H.S.3
-
43
-
-
42649145667
-
Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Freeman D, et al: Wildtype KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 26:1626-1634, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Freeman, D.3
|