Anti-neutrophil cytoplasmic antibodies target sequential functional proteinase 3 epitopes in the sera of patients with Wegener's granulomatosis

Clinical and Experimental Immunology

Volumn 162, Issue 2, 2010, Pages 262-270

  Bruner, B F ^a   Vista, E S ^a   Wynn, D M ^b   Harley, J B ^a   James, J A ^c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Epitope mapping; PR3; Vasculitis; Wegener's granulomatosis

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; EPITOPE; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; OCTAPEPTIDE;

ADULT; AGED; AMINO ACID SEQUENCE; ANTIGENICITY; ARTICLE; B LYMPHOCYTE; BINDING SITE; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOREACTIVITY; MALE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; SOLID PHASE SYNTHESIS; WEGENER GRANULOMATOSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; AMINO ACID SEQUENCE; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; EPITOPES, B-LYMPHOCYTE; FEMALE; HUMANS; ISOELECTRIC POINT; MALE; MIDDLE AGED; MODELS, MOLECULAR; MYELOBLASTIN; PEPTIDE FRAGMENTS; SURFACE PROPERTIES; WEGENER GRANULOMATOSIS; YOUNG ADULT;

EID: 78649308210     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2010.04251.x     Document Type: Article

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