Plasma levels of endothelial protein C receptor respond to anticoagulant treatment

Blood

Volumn 99, Issue 2, 2002, Pages 526-530

  Stearns Kurosawa, Deborah J ^a,b,c   Swindle, Kandice ^a,b,c   D'Angelo, Armando ^a,b,c   Della Valle, Patrizia ^a,b,c   Fattorini, Annalisa ^a,b,c   Caron, Nathalie ^a,b,c   Grimaux, Marc ^a,b,c   Woodhams, Barry ^a,b,c   Kurosawa, Shinichiro ^a,b,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c Serbio Diagnostica Stago   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; COUMARIN; HEPARIN; METALLOPROTEINASE; PROTEIN C; PROTEIN C RECEPTOR; PROTHROMBIN; RECEPTOR PROTEIN; THROMBIN; UNCLASSIFIED DRUG; WARFARIN;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEMALE; HEART ATRIUM FIBRILLATION; HEART DILATATION; HEART INFARCTION; HUMAN; HUMAN EXPERIMENT; HYPERCOAGULABILITY; IN VIVO STUDY; INTERNATIONAL STANDARD UNIT; MALE; MITRAL VALVE DISEASE; NORMAL HUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THROMBOEMBOLISM; THROMBOSIS; UNSTABLE ANGINA PECTORIS; VASCULAR ENDOTHELIUM;

EID: 0037079736     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.2.526     Document Type: Article

References (28)

1. Disseminated intravascular coagulation: Clinical and laboratory aspects
2. Management of patients with hereditary hypercoagulable disorders
3. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease
4. Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
5. Oral anticoagulant drugs: Pharmacokinetic aspects
6. Regulation and functions of the protein C anticoagulant pathway
7. Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR): The structural and functional conservation in human, bovine, and murine EPCR
8. Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor
9. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
10. Human protein C receptor is present primarily on endothelium of large blood vessels: Implications for the control of the protein C pathway
11. The endothelial cell protein C receptor (EPCR) functions as a primary receptor for protein C activation on endothelial cells in arteries, veins, and capillaries
12. Identification of functional endothelial protein C receptor in human plasma
13. The soluble endothelial protein C receptor binds to activated neutrophils: Involvement of proteinase-3 and CDllb/CD18
14. Metalloproteolytic release of endothelial protein C receptor
15. Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo
16. Characterization and regulation of the 5′-flanking region of the murine endothelial protein C receptor gene
17. Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: Lack of correlation with thrombomodulin suggests involvement of different pathological processes
18. Relationship between protein C antigen and anticoagulant activity during oral anticoagulation and in selected disease states
19. The endothelial cell protein C receptor: Cell surface expression and direct ligand binding by the soluble receptor
20. Effective warfarin-dependent inhibition of prothrombin activation occurs after the reduction of plasma factor II
21. Aspects of anticoagulant action: A review of the pharmacology, metabolism and toxicology of warfarin and congeners
22. Granulocyte proteases and hydrogen peroxide synergistically inactivate thrombomodulin of endothelial cells in vitro
23. Plasma thrombomodulin in health and diseases
24. Circulating thrombomodulin as a novel endothelial cell marker: Comparison of its behavior with von Willebrand factor and tissue-type plasminogen activator
25. Thrombomodulin: An overview and potential implications in vascular disorders
26. The thrombogram: Monitoring thrombin generation in platelet rich plasma
27. Clinical utilization of the international normalized ratio (INR)
28. Dosing practices of physicians for anticoagulation with warfarin during inpatient rehabilitation