-
1
-
-
33745728461
-
Fatty acid synthase and cancer: New application of an old pathway
-
Kuhajda FP. Fatty acid synthase and cancer: new application of an old pathway. Cancer Res 2006;66:5977-80.
-
(2006)
Cancer Res
, vol.66
, pp. 5977-5980
-
-
Kuhajda, F.P.1
-
2
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 2007;7:763-77.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
5
-
-
56649086770
-
Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer
-
Fiorentino M, Zadra G, Palescandolo E, et al. Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer. Lab Invest 2008;88:1340-8.
-
(2008)
Lab Invest
, vol.88
, pp. 1340-1348
-
-
Fiorentino, M.1
Zadra, G.2
Palescandolo, E.3
-
6
-
-
63649099458
-
Fatty acid synthase: A metabolic enzyme and candidate oncogene in prostate cancer
-
Migita T, Ruiz S, Fornari A, et al. Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst 2009;101:519-32.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 519-532
-
-
Migita, T.1
Ruiz, S.2
Fornari, A.3
-
7
-
-
0028306459
-
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
-
Turner DL, Weintraub H. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev 1994;8:1434-47.
-
(1994)
Genes Dev
, vol.8
, pp. 1434-1447
-
-
Turner, D.L.1
Weintraub, H.2
-
8
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferre P, Foufelle F. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci U S A 1999;96:12737-42.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferre, P.3
Foufelle, F.4
-
9
-
-
84988075033
-
Isolation and structure elucidation of soraphen A1, a novel antifungal macrolide from Sorangium cellulosum
-
Bedorf N, Schomburg D, Gerth K, Reichenbach H, Hofle G. Isolation and structure elucidation of soraphen A1, a novel antifungal macrolide from Sorangium cellulosum. Liebigs Ann Chem 1993;9:1017-21.
-
(1993)
Liebigs Ann Chem
, vol.9
, pp. 1017-1021
-
-
Bedorf, N.1
Schomburg, D.2
Gerth, K.3
Reichenbach, H.4
Hofle, G.5
-
10
-
-
0028154083
-
The soraphens: A family of novel antifungal compounds from Sorangium cellulosum (Myxobacteria). I. Soraphen A1 α: Fermentation, isolation, biological properties
-
Gerth K, Bedorf N, Irschik H, Hofle G, Reichenbach H. The soraphens: a family of novel antifungal compounds from Sorangium cellulosum (Myxobacteria). I. Soraphen A1 α: fermentation, isolation, biological properties. J Antibiot 1994;47:23-31.
-
(1994)
J Antibiot
, vol.47
, pp. 23-31
-
-
Gerth, K.1
Bedorf, N.2
Irschik, H.3
Hofle, G.4
Reichenbach, H.5
-
11
-
-
34548580317
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
-
Beckers A, Organe S, Timmermans L, et al. Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. Cancer Res 2007;67:8180-7.
-
(2007)
Cancer Res
, vol.67
, pp. 8180-8187
-
-
Beckers, A.1
Organe, S.2
Timmermans, L.3
-
12
-
-
0034718771
-
Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
-
Swinnen JV, Heemers H, Deboel L, Foufelle F, Heyns W, Verhoeven G. Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene 2000;19:5173-81.
-
(2000)
Oncogene
, vol.19
, pp. 5173-5181
-
-
Swinnen, J.V.1
Heemers, H.2
Deboel, L.3
Foufelle, F.4
Heyns, W.5
Verhoeven, G.6
-
13
-
-
0027401529
-
Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus
-
Christian JL, Moon RT. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev 1993;7:13-28.
-
(1993)
Genes Dev
, vol.7
, pp. 13-28
-
-
Christian, J.L.1
Moon, R.T.2
-
14
-
-
0028948854
-
Cyclopamine, a steroidal alkaloid, disrupts development of cranial neural crest cells in Xenopus
-
Dunn MK, Mercola M, Moore DD. Cyclopamine, a steroidal alkaloid, disrupts development of cranial neural crest cells in Xenopus. Dev Dyn 1995;202:255-70.
-
(1995)
Dev Dyn
, vol.202
, pp. 255-270
-
-
Dunn, M.K.1
Mercola, M.2
Moore, D.D.3
-
15
-
-
26644460824
-
Vertebrate smoothened functions at the primary cilium
-
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. Vertebrate smoothened functions at the primary cilium. Nature 2005;437:1018-21.
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
16
-
-
37749054886
-
Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
-
Corbit KC, Shyer AE, Dowdle WE, et al. Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat Cell Biol 2008;10:70-6.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 70-76
-
-
Corbit, K.C.1
Shyer, A.E.2
Dowdle, W.E.3
-
17
-
-
35648985644
-
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
-
Gerdes JM, Liu Y, Zaghloul NA, et al. Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nat Genet 2007;39:1350-60.
-
(2007)
Nat Genet
, vol.39
, pp. 1350-1360
-
-
Gerdes, J.M.1
Liu, Y.2
Zaghloul, N.A.3
-
18
-
-
23844485210
-
Cilia and Hedgehog responsiveness in the mouse
-
Huangfu D, Anderson KV. Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 2005;102:11325-30.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 11325-11330
-
-
Huangfu, D.1
Anderson, K.V.2
-
19
-
-
37549052499
-
Ciliary proteins link basal body polarization to planar cell polarity regulation
-
Jones C, Roper VC, Foucher I, et al. Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet 2008;40:69-77.
-
(2008)
Nat Genet
, vol.40
, pp. 69-77
-
-
Jones, C.1
Roper, V.C.2
Foucher, I.3
-
20
-
-
23144466931
-
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
-
Liu A, Wang B, Niswander LA. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 2005;132:3103-11.
-
(2005)
Development
, vol.132
, pp. 3103-3111
-
-
Liu, A.1
Wang, B.2
Niswander, L.A.3
-
21
-
-
33644624937
-
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
-
Park TJ, Haigo SL, Wallingford JB. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet 2006;38:303-11.
-
(2006)
Nat Genet
, vol.38
, pp. 303-311
-
-
Park, T.J.1
Haigo, S.L.2
Wallingford, J.B.3
-
22
-
-
63049116544
-
The vertebrate primary cilium in development, homeostasis, and disease
-
Gerdes JM, Davis EE, Katsanis N. The vertebrate primary cilium in development, homeostasis, and disease. Cell 2009;137:32-45.
-
(2009)
Cell
, vol.137
, pp. 32-45
-
-
Gerdes, J.M.1
Davis, E.E.2
Katsanis, N.3
-
23
-
-
33947384151
-
Overview of structure and function of mammalian cilia
-
Satir P, Christensen ST. Overview of structure and function of mammalian cilia. Ann Rev Physiol 2007;69:377-400.
-
(2007)
Ann Rev Physiol
, vol.69
, pp. 377-400
-
-
Satir, P.1
Christensen, S.T.2
-
24
-
-
33746891890
-
The primary cilium as the cell's antenna: Signaling at a sensory organelle
-
Singla V, Reiter JF. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 2006;313:629-33.
-
(2006)
Science
, vol.313
, pp. 629-633
-
-
Singla, V.1
Reiter, J.F.2
-
25
-
-
0029041316
-
Human acetyl-CoA carboxylase: Characterization, molecular cloning, and evidence for two isoforms
-
Abu-Elheiga L, Jayakumar A, Baldini A, Chirala SS, Wakil SJ. Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms. Proc Natl Acad Sci U S A 1995;92:4011-5.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4011-4015
-
-
Abu-Elheiga, L.1
Jayakumar, A.2
Baldini, A.3
Chirala, S.S.4
Wakil, S.J.5
-
26
-
-
63049100252
-
Deciliation is associated with dramatic remodeling of epithelial cell junctions and surface domains
-
Overgaard CE, Sanzone KM, Spiczka KS, Sheff DR, Sandra A, Yeaman C. Deciliation is associated with dramatic remodeling of epithelial cell junctions and surface domains. Mol Biol Cell 2008;20:102-13.
-
(2008)
Mol Biol Cell
, vol.20
, pp. 102-113
-
-
Overgaard, C.E.1
Sanzone, K.M.2
Spiczka, K.S.3
Sheff, D.R.4
Sandra, A.5
Yeaman, C.6
-
27
-
-
33845487091
-
FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells
-
Vieira OV, Gaus K, Verkade P, Fullekrug J, Vaz WL, Simons K. FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells. Proc Natl Acad Sci U S A 2006;103:18556-61.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18556-18561
-
-
Vieira, O.V.1
Gaus, K.2
Verkade, P.3
Fullekrug, J.4
Vaz, W.L.5
Simons, K.6
-
28
-
-
34248196504
-
A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135
-
Yu CY, Chen JY, Lin YY, et al. A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135. Mol Biol Cell 2007;18:1710-22.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1710-1722
-
-
Yu, C.Y.1
Chen, J.Y.2
Lin, Y.Y.3
-
29
-
-
25444443688
-
Modelling glandular epithelial cancers in three-dimensional cultures
-
Debnath J, Brugge JS. Modelling glandular epithelial cancers in three-dimensional cultures. Nat Rev Cancer 2005;5:675-88.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 675-688
-
-
Debnath, J.1
Brugge, J.S.2
-
30
-
-
0037428084
-
Tube morphogenesis: Making and shaping biological tubes
-
Lubarsky B, Krasnow MA. Tube morphogenesis: making and shaping biological tubes. Cell 2003;112:19-28.
-
(2003)
Cell
, vol.112
, pp. 19-28
-
-
Lubarsky, B.1
Krasnow, M.A.2
-
31
-
-
0036636095
-
Opinion: Building epithelial architecture: insights from three-dimensional culture models
-
O'Brien LE, Zegers MM, Mostov KE. Opinion: building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol 2002;3:531-7.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 531-537
-
-
O'Brien, L.E.1
Zegers, M.M.2
Mostov, K.E.3
-
32
-
-
56049120376
-
All along the watchtower: Is the cilium a tumor suppressor organelle?
-
Mans DA, Voest EE, Giles RH. All along the watchtower: is the cilium a tumor suppressor organelle? Biochim Biophys Acta 2008;1786:114-25.
-
(2008)
Biochim Biophys Acta
, vol.1786
, pp. 114-125
-
-
Mans, D.A.1
Voest, E.E.2
Giles, R.H.3
-
33
-
-
33746528106
-
Cilia: Tuning in to the cell's antenna
-
Marshall WF, Nonaka S. Cilia: tuning in to the cell's antenna. Curr Biol 2006;16:R604-14.
-
(2006)
Curr Biol
, vol.16
-
-
Marshall, W.F.1
Nonaka, S.2
-
35
-
-
58349099851
-
Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia
-
Seeley ES, Carriere C, Goetze T, Longnecker DS, Korc M. Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia. Cancer Res 2009;69:422-30.
-
(2009)
Cancer Res
, vol.69
, pp. 422-430
-
-
Seeley, E.S.1
Carriere, C.2
Goetze, T.3
Longnecker, D.S.4
Korc, M.5
-
36
-
-
33846785192
-
Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
-
Dawe HR, Farr H, Gull K. Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells. J Cell Sci 2007;120:7-15.
-
(2007)
J Cell Sci
, vol.120
, pp. 7-15
-
-
Dawe, H.R.1
Farr, H.2
Gull, K.3
-
38
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
Porstmann T, Santos CR, Griffiths B, et al. SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab 2008;8:224-36.
-
(2008)
Cell Metab
, vol.8
, pp. 224-236
-
-
Porstmann, T.1
Santos, C.R.2
Griffiths, B.3
-
39
-
-
71949088022
-
Can faulty antennae increase adiposity? The link between cilia proteins and obesity
-
Sen Gupta P, Prodromou N, Chapple J. Can faulty antennae increase adiposity? The link between cilia proteins and obesity. J Endocrinol 2009;203:327-36.
-
(2009)
J Endocrinol
, vol.203
, pp. 327-336
-
-
Sen Gupta, P.1
Prodromou, N.2
Chapple, J.3
|