A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135

Molecular Biology of the Cell

Volumn 18, Issue 5, 2007, Pages 1710-1722

  Yu, Chun Ying ^a   Chen, Jen Yau ^a   Lin, Yu Yu ^a   Shen, Kuo Fang ^a   Lin, Wei Ling ^a   Chien, Chung Liang ^b   Ter Beest, Martin B A ^c   Jou, Tzuu Shuh ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EZRIN; MEMBRANE PROTEIN; NEUROMODULIN; PDZ PROTEIN; PODOCALYXIN;

ANIMAL CELL; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; CYTOPLASM; GLYCOSYLATION; GOLGI COMPLEX; MUTANT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN SYNTHESIS; PROTEIN TARGETING;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CELL POLARITY; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DOGS; ENDOCYTOSIS; GLYCOSYLATION; MEMBRANE MICRODOMAINS; MODELS, BIOLOGICAL; MUTATION; PROTEIN KINASE C; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; RNA, SMALL INTERFERING; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION;

EID: 34248196504     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-07-0629     Document Type: Article

References (40)

1. Bretscher, A. (1999). Regulation of cortical structure by the ezrin-radixinmoesin protein family. Curr. Opin. Cell Biol. 11, 109-116.
2. Bretscher, A., Reczek, D., and Berryman, M. (1997). Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures. J. Cell Sci. 110(Pt 24), 3011-3018.
3. Brone, B., and Eggermont, J. (2005). PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes. Am. J. Physiol. Cell Physiol. 288, C20-C29.
4. Brown, D. A., Crise, B., and Rose, J. K. (1989). Mechanism of membrane anchoring affects polarized expression of two proteins in MDCK cells. Science 245, 1499-1501.
5. Brown, D. A., and Rose, J. K. (1992). Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 68, 533-544.
6. Cao, T. T., Deacon, H. W., Reczek, D., Bretscher, A., and von Zastrow, M. (1999). A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature 401, 286-290.
7. Carrasco, M., Amorim, M. J., and Digard, P. (2004). Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane. Traffic 5, 979-992.
8. Chen, Y. T., Stewart, D. B., and Nelson, W. J. (1999). Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells. J. Cell Biol. 144, 687-699.
9. Cheng, H. Y. et al. (2005). Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator. J. Am. Soc. Nephrol. 16, 1612-1622.
10. Chuang, J. Z., and Sung, C. H. (1998). The cytoplasmic tail of rhodopsin acts as a novel apical sorting signal in polarized MDCK cells. J. Cell Biol. 142, 1245-1256.
11. Doyonnas, R., Kershaw, D. B., Duhme, C., Merkens, H., Chelliah, S., Graf, T., and McNagny, K. M. (2001). Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. J. Exp. Med. 194, 13-27.
12. Griffiths, G., and Simons, K. (1986). The trans Golgi network: sorting at the exit site of the Golgi complex. Science 234, 438-443.
13. Haller, C., and Alper, S. L. (1993). Nonpolarized surface distribution and delivery of human CD7 in polarized MDCK cells. Am. J. Physiol. 265, C1069-C1079.
14. Hannan, L. A., Lisanti, M. P., Rodriguez-Boulan, E., and Edidin, M. (1993). Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J. Cell Biol. 120, 353-358.
15. Harris, B. Z., and Lim, W. A. (2001). Mechanism and role of PDZ domains in signaling complex assembly. J. Cell Sci. 114, 3219-3231.
16. Hinck, L., Nathke, I. S., Papkoff, J., and Nelson, W. J. (1994). Dynamics of cadherin/ catenin complex formation: novel protein interactions and pathways of complex assembly. J. Cell Biol. 125, 1327-1340.
17. Hunziker, W., and Fumey, C. (1994). A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells. EMBO J. 13, 2963-2969.
18. Kerjaschki, D., Sharkey, D. J., and Farquhar, M. G. (1984). Identification and characterization of podocalyxin - the major sialoprotein of the renal glomerular epithelial cell. J. Cell Biol. 98, 1591-1596.
19. Kerjaschki, D., Vernillo, A. T., and Farquhar, M. G. (1985). Reduced sialylation of podocalyxin - the major sialoprotein of the rat kidney glomerulus - in aminonucleoside nephrosis. Am. J. Pathol. 118, 343-349.
20. Lau, A. G., and Hall, R. A. (2001). Oligomerization of NHERF-1 and NHERF-2 PDZ domains: differential regulation by association with receptor carboxyltermini and by phosphorylation. Biochemistry 40, 8572-8580.
21. Le Bivic, A., Real, F. X., and Rodriguez-Boulan, E. (1989). Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc. Natl. Acad. Sci. USA 86, 9313-9317.
22. Le, T. L., Joseph, S. R., Yap, A. S., and Stow, J. L. (2002). Protein kinase C regulates endocytosis and recycling of E-cadherin. Am. J. Physiol. Cell Physiol. 283, C489-C499.
23. Li, Y., Li, J., Straight, S. W., and Kershaw, D. B. (2002). PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2. Am. J. Physiol. Renal Physiol. 282, F1129-F1139.
24. Lisanti, M. P., Caras, I. W., Davitz, M. A., and Rodriguez-Boulan, E. (1989). A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J. Cell Biol. 109, 2145-2156.
25. Matlin, K. S., and Simons, K. (1983). Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation. Cell 34, 233-243.
26. Matter, K., Yamamoto, E. M., and Mellman, I. (1994). Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells. J. Cell Biol. 126, 991-1004.
27. Meder, D., Shevchenko, A., Simons, K., and Fullekrug, J. (2005). Gp135/ podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. J. Cell Biol. 168, 303-313.
28. Moyer, B. D. et al. (1999). A PDZ-interacting domain in CFTR is an apical membrane polarization signal. J. Clin. Invest. 104, 1353-1361.
29. Orlando, R. A., Takeda, T., Zak, B., Schmieder, S., Benoit, V. M., McQuistan, T., Furthmayr, H., and Farquhar, M. G. (2001). The glomerular epithelial cell anti-adhesin podocalyxin associates with the actin cytoskeleton through interactions with ezrin. J. Am. Soc. Nephrol. 12, 1589-1598.
30. Paladino, S., Sarnataro, D., Pillich, R., Tivodar, S., Nitsch, L., and Zurzolo, C. (2004). Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins. J. Cell Biol. 167, 699-709.
31. Reczek, D., Berryman, M., and Bretscher, A. (1997). Identification of EBP50, a PDZ-containing phosphoprotein that associates with members of the ezrinradixin-moesin family. J. Cell Biol. 139, 169-179.
32. Rodriguez-Boulan, E., and Musch, A. (2005). Protein sorting in the Golgi complex: shifting paradigms. Biochim. Biophys. Acta 1744, 455-464.
33. Scheiffele, P., Peranen, J., and Simons, K. (1995). N-glycans as apical sorting signals in epithelial cells. Nature 378, 96-98.
34. Schmieder, S., Nagai, M., Orlando, R. A., Takeda, T., and Farquhar, M. G. (2004). Podocalyxin activates RhoA and induces actin reorganization through NHERF1 and Ezrin in MDCK cells. J. Am. Soc. Nephrol. 15, 2289-2298.
35. Sheets, E. D., Lee, G. M., Simson, R., and Jacobson, K. (1997). Transient confinement of a glycosylphosphatidylinositol-anchored protein in the plasma membrane. Biochemistry 36, 12449-12458.
36. Shvartsman, D. E., Kotler, M., Tall, R. D., Roth, M. G., and Henis, Y. I. (2003). Differently anchored influenza hemagglutinin mutants display distinct interaction dynamics with mutual rafts. J. Cell Biol. 163, 879-888.
37. Simons, K., and Vaz, W. L. (2004). Model systems, lipid rafts, and cell membranes. Annu. Rev. Biophys. Biomol. Struct. 33, 269-295.
38. Takeda, T., McQuistan, T., Orlando, R. A., and Farquhar, M. G. (2001). Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. J. Clin. Invest. 108, 289-301.
39. Yeaman, C., Le Gall, A. H., Baldwin, A. N., Monlauzeur, L., Le Bivic, A., and Rodriguez-Boulan, E. (1997). The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. J. Cell Biol. 139, 929-940.
40. Zurzolo, C., van Meer, G., and Mayor, S. (2003). The order of rafts. Conference on microdomains, lipid rafts and caveolae. EMBO Rep. 4, 1117-1121.