-
1
-
-
0037152635
-
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer
-
Osada H, Takahashi T. Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer. Oncogene 2002;21:7421-34.
-
(2002)
Oncogene
, vol.21
, pp. 7421-7434
-
-
Osada, H.1
Takahashi, T.2
-
3
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434:864-70.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
-
4
-
-
37049016679
-
Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer
-
Ebi H, Matsuo K, Sugito N, et al. Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. Cancer Res 2007;67:11158-65.
-
(2007)
Cancer Res
, vol.67
, pp. 11158-11165
-
-
Ebi, H.1
Matsuo, K.2
Sugito, N.3
-
5
-
-
70349464806
-
Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers
-
Ebi H, Sato T, Sugito N, et al. Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers. Oncogene 2009;28:3371-9.
-
(2009)
Oncogene
, vol.28
, pp. 3371-3379
-
-
Ebi, H.1
Sato, T.2
Sugito, N.3
-
6
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005;434:907-13.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
-
7
-
-
0036141604
-
Identification of frequent G(2) checkpoint impairment and a homozygous deletion of 14-3-3ε at 17p13.3 in small cell lung cancers
-
Konishi H, Nakagawa T, Harano T, et al. Identification of frequent G(2) checkpoint impairment and a homozygous deletion of 14-3-3ε at 17p13.3 in small cell lung cancers. Cancer Res 2002;62:271-6.
-
(2002)
Cancer Res
, vol.62
, pp. 271-276
-
-
Konishi, H.1
Nakagawa, T.2
Harano, T.3
-
8
-
-
3142707257
-
Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines
-
Nakagawa T, Hayashita Y, Maeno K, et al. Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines. Cancer Res 2004;64:4826-32.
-
(2004)
Cancer Res
, vol.64
, pp. 4826-4832
-
-
Nakagawa, T.1
Hayashita, Y.2
Maeno, K.3
-
9
-
-
38349099227
-
Initiating the uninitiated: Replication of damaged DNA and carcinogenesis
-
Kaufmann WK. Initiating the uninitiated: replication of damaged DNA and carcinogenesis. Cell Cycle 2007;6:1460-7.
-
(2007)
Cell Cycle
, vol.6
, pp. 1460-1467
-
-
Kaufmann, W.K.1
-
10
-
-
17044411374
-
Mutator phenotype in cancer: Timing and perspectives
-
Bielas JH, Loeb LA. Mutator phenotype in cancer: timing and perspectives. Environ Mol Mutagen 2005;45:206-13.
-
(2005)
Environ Mol Mutagen
, vol.45
, pp. 206-213
-
-
Bielas, J.H.1
Loeb, L.A.2
-
11
-
-
0035890776
-
Heterogeneous transforming growth factor (TGF)-β unresponsiveness and loss of TGF-β receptor type II expression caused by histone deacetylation in lung cancer cell lines
-
Osada H, Tatematsu Y, Masuda A, et al. Heterogeneous transforming growth factor (TGF)-β unresponsiveness and loss of TGF-β receptor type II expression caused by histone deacetylation in lung cancer cell lines. Cancer Res 2001;61:8331-9.
-
(2001)
Cancer Res
, vol.61
, pp. 8331-8339
-
-
Osada, H.1
Tatematsu, Y.2
Masuda, A.3
-
12
-
-
28844469300
-
Histone modification in the TGFβRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines
-
Osada H, Tatematsu Y, Sugito N, Horio Y, Takahashi T. Histone modification in the TGFβRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. Mol Carcinog 2005;44:233-41.
-
(2005)
Mol Carcinog
, vol.44
, pp. 233-241
-
-
Osada, H.1
Tatematsu, Y.2
Sugito, N.3
Horio, Y.4
Takahashi, T.5
-
13
-
-
36749059976
-
Dynamics of human replication factors in the elongation phase of DNA replication
-
Masuda Y, Suzuki M, Piao J, Gu Y, Tsurimoto T, Kamiya K. Dynamics of human replication factors in the elongation phase of DNA replication. Nucleic Acids Res 2007;35:6904-16.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 6904-6916
-
-
Masuda, Y.1
Suzuki, M.2
Piao, J.3
Gu, Y.4
Tsurimoto, T.5
Kamiya, K.6
-
14
-
-
33645804773
-
Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors
-
Takeuchi T, Tomida S, Yatabe Y, et al. Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors. J Clin Oncol 2006;24:1679-88.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1679-1688
-
-
Takeuchi, T.1
Tomida, S.2
Yatabe, Y.3
-
15
-
-
30944452765
-
Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ
-
Pavlov YI, Frahm C, McElhinny SA, Niimi A, Suzuki M, Kunkel TA. Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ. Curr Biol 2006;16:202-7.
-
(2006)
Curr Biol
, vol.16
, pp. 202-207
-
-
Pavlov, Y.I.1
Frahm, C.2
McElhinny, S.A.3
Niimi, A.4
Suzuki, M.5
Kunkel, T.A.6
-
16
-
-
33845496081
-
Roles of DNA polymerases in replication, repair, and recombination in eukaryotes
-
Pavlov YI, Shcherbakova PV, Rogozin IB. Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Int Rev Cytol 2006;255:41-132.
-
(2006)
Int Rev Cytol
, vol.255
, pp. 41-132
-
-
Pavlov, Y.I.1
Shcherbakova, P.V.2
Rogozin, I.B.3
-
17
-
-
33744965571
-
Functional roles of p12, the fourth subunit of human DNA polymerase δ
-
Li H, Xie B, Zhou Y, et al. Functional roles of p12, the fourth subunit of human DNA polymerase δ. J Biol Chem 2006;281:14748-55.
-
(2006)
J Biol Chem
, vol.281
, pp. 14748-14755
-
-
Li, H.1
Xie, B.2
Zhou, Y.3
-
18
-
-
0037040170
-
Reconstitution of human DNA polymerase δ using recombinant baculoviruses: The p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme
-
Podust VN, Chang LS, Ott R, Dianov GL, Fanning E. Reconstitution of human DNA polymerase δ using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme. J Biol Chem 2002;277:3894-901.
-
(2002)
J Biol Chem
, vol.277
, pp. 3894-3901
-
-
Podust, V.N.1
Chang, L.S.2
Ott, R.3
Dianov, G.L.4
Fanning, E.5
-
19
-
-
77952101773
-
Functions of base selection step in human DNA polymerase α
-
(Amst)
-
Tanaka S, Cao K, Niimi A, et al. Functions of base selection step in human DNA polymerase α. DNA Repair (Amst) 2010;9:534-41.
-
(2010)
DNA Repair
, vol.9
, pp. 534-541
-
-
Tanaka, S.1
Cao, K.2
Niimi, A.3
-
20
-
-
0031757126
-
Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division
-
Reynolds N, Watt A, Fantes PA, MacNeill SA. Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division. Curr Genet 1998;34:250-8.
-
(1998)
Curr Genet
, vol.34
, pp. 250-258
-
-
Reynolds, N.1
Watt, A.2
Fantes, P.A.3
MacNeill, S.A.4
-
21
-
-
13944275951
-
FGF2-induced upregulation of DNA polymerase-δ p12 subunit in endothelial cells
-
Dell'Era P, Nicoli S, Peri G, Nieddu M, Ennas MG, Presta M. FGF2-induced upregulation of DNA polymerase-δ p12 subunit in endothelial cells. Oncogene 2005;24:1117-21.
-
(2005)
Oncogene
, vol.24
, pp. 1117-1121
-
-
Dell'Era, P.1
Nicoli, S.2
Peri, G.3
Nieddu, M.4
Ennas, M.G.5
Presta, M.6
-
22
-
-
72949101986
-
Roles of POLD4, smallest subunit of DNA polymerase δ, in nuclear structures and genomic stability of human cells
-
Huang QM, Akashi T, Masuda Y, Kamiya K, Takahashi T, Suzuki M. Roles of POLD4, smallest subunit of DNA polymerase δ, in nuclear structures and genomic stability of human cells. Biochem Biophys Res Commun 2010;391:542-6.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 542-546
-
-
Huang, Q.M.1
Akashi, T.2
Masuda, Y.3
Kamiya, K.4
Takahashi, T.5
Suzuki, M.6
-
23
-
-
0037037806
-
Chromosome instability in human lung cancers: Possible underlying mechanisms and potential consequences in the pathogenesis
-
Masuda A, Takahashi T. Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis. Oncogene 2002;21:6884-97.
-
(2002)
Oncogene
, vol.21
, pp. 6884-6897
-
-
Masuda, A.1
Takahashi, T.2
-
24
-
-
1642403670
-
Palm mutants in DNA polymerases α and η alter DNA replication fidelity and translesion activity
-
Niimi A, Limsirichaikul S, Yoshida S, et al. Palm mutants in DNA polymerases α and η alter DNA replication fidelity and translesion activity. Mol Cell Biol 2004;24:2734-46.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2734-2746
-
-
Niimi, A.1
Limsirichaikul, S.2
Yoshida, S.3
-
25
-
-
70350126567
-
DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice
-
Albertson TM, Ogawa M, Bugni JM, et al. DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci U S A 2009;106:17101-4.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17101-17104
-
-
Albertson, T.M.1
Ogawa, M.2
Bugni, J.M.3
-
26
-
-
0038604759
-
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase α
-
Ogawa M, Limsirichaikul S, Niimi A, Iwai S, Yoshida S, Suzuki M. Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase α. J Biol Chem 2003;278:19071-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 19071-19078
-
-
Ogawa, M.1
Limsirichaikul, S.2
Niimi, A.3
Iwai, S.4
Yoshida, S.5
Suzuki, M.6
-
27
-
-
0033800646
-
Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase δ or by decreases in the cellular levels of DNA polymerase δ
-
Kokoska RJ, Stefanovic L, DeMai J, Petes TD. Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase δ or by decreases in the cellular levels of DNA polymerase δ. Mol Cell Biol 2000;20:7490-504.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7490-7504
-
-
Kokoska, R.J.1
Stefanovic, L.2
DeMai, J.3
Petes, T.D.4
-
28
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance ED, Stephens PJ, O'Meara S, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010;463:184-90.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
Stephens, P.J.2
O'Meara, S.3
-
29
-
-
77953006634
-
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
-
Lee W, Jiang Z, Liu J, et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature 2010;465:473-7.
-
(2010)
Nature
, vol.465
, pp. 473-477
-
-
Lee, W.1
Jiang, Z.2
Liu, J.3
-
30
-
-
50249159576
-
Reduced levels of DNA polymerase δ induce chromosome fragile site instability in yeast
-
Lemoine FJ, Degtyareva NP, Kokoska RJ, Petes TD. Reduced levels of DNA polymerase δ induce chromosome fragile site instability in yeast. Mol Cell Biol 2008;28:5359-68.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5359-5368
-
-
Lemoine, F.J.1
Degtyareva, N.P.2
Kokoska, R.J.3
Petes, T.D.4
-
31
-
-
14844286404
-
Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
-
Lemoine FJ, Degtyareva NP, Lobachev K, Petes TD. Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell 2005;120:587-98.
-
(2005)
Cell
, vol.120
, pp. 587-598
-
-
Lemoine, F.J.1
Degtyareva, N.P.2
Lobachev, K.3
Petes, T.D.4
-
32
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
Weir BA, Woo MS, Getz G, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature 2007;450:893-8.
-
(2007)
Nature
, vol.450
, pp. 893-898
-
-
Weir, B.A.1
Woo, M.S.2
Getz, G.3
-
33
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L, Getz G, Wheeler DA, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008;455:1069-75.
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
Getz, G.2
Wheeler, D.A.3
-
34
-
-
0028270326
-
Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer
-
Merlo A, Gabrielson E, Mabry M, Vollmer R, Baylin SB, Sidransky D. Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer. Cancer Res 1994;54:2322-6.
-
(1994)
Cancer Res
, vol.54
, pp. 2322-2326
-
-
Merlo, A.1
Gabrielson, E.2
Mabry, M.3
Vollmer, R.4
Baylin, S.B.5
Sidransky, D.6
-
35
-
-
0029030266
-
Identification of novel regions of altered DNA copy number in small cell lung tumors
-
Levin NA, Brzoska PM, Warnock ML, Gray JW, Christman MF. Identification of novel regions of altered DNA copy number in small cell lung tumors. Genes Chromosomes Cancer 1995;13:175-85.
-
(1995)
Genes Chromosomes Cancer
, vol.13
, pp. 175-185
-
-
Levin, N.A.1
Brzoska, P.M.2
Warnock, M.L.3
Gray, J.W.4
Christman, M.F.5
-
36
-
-
0346096758
-
Small cell lung cancer: From molecular biology to novel therapeutics
-
Pisick E, Jagadeesh S, Salgia R. Small cell lung cancer: from molecular biology to novel therapeutics. J Exp Ther Oncol 2003;3:305-18.
-
(2003)
J Exp Ther Oncol
, vol.3
, pp. 305-318
-
-
Pisick, E.1
Jagadeesh, S.2
Salgia, R.3
-
37
-
-
0021273286
-
Serumdependent "cannibalism" and autodestruction in cultures of human small cell carcinoma of the lung
-
Brouwer M, de Ley L, Feltkamp CA, Elema J, Jongsma AP. Serumdependent "cannibalism" and autodestruction in cultures of human small cell carcinoma of the lung. Cancer Res 1984;44:2947-51.
-
(1984)
Cancer Res
, vol.44
, pp. 2947-2951
-
-
Brouwer, M.1
De Ley, L.2
Feltkamp, C.A.3
Elema, J.4
Jongsma, A.P.5
-
38
-
-
36348944160
-
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior
-
Liontos M, Koutsami M, Sideridou M, et al. Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res 2007;67:10899-909.
-
(2007)
Cancer Res
, vol.67
, pp. 10899-10909
-
-
Liontos, M.1
Koutsami, M.2
Sideridou, M.3
|