Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase α

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 19071-19078

  Ogawa, Masanori ^a   Limsirichaikul, Siripan ^a   Niimi, Atsuko ^a   Iwai, Shigenori ^b   Yoshida, Shonen ^a   Suzuki, Motoshi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CATALYSIS; DNA; GENETIC ENGINEERING; YEAST;

DNA POLYMERASES;

AMINO ACIDS;

AMINO ACID; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; FUNGAL DNA; GLYCINE; LYSINE; 2'-DEOXYGUANOSINE 5'-PHOSPHATE; DEOXYGUANOSINE PHOSPHATE; TAQ POLYMERASE;

ACCURACY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; CATALYSIS; CATALYST; COLONY FORMATION; DNA SYNTHESIS; ENZYME ACTIVITY; GENETIC COMPLEMENTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PURIFICATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; TEMPERATURE SENSITIVE MUTANT; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENE LIBRARY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; BASE PAIRING; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; DEOXYGUANINE NUCLEOTIDES; DNA POLYMERASE I; DNA, FUNGAL; GENE DELETION; GENE LIBRARY; GLYCINE; KINETICS; LYSINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TAQ POLYMERASE;

EID: 0038604759     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208605200     Document Type: Article

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